Best TWAS P=5.48e-17 · Best GWAS P=3.26e-20 conditioned to 0.000149
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | CACNA2D4 | 0.19 | 0.04 | lasso | 5 | 0.01 | 9.2e-02 | 8.9 | -8.4 | 5.5e-17 | -0.87 | 0.04 | 0.50 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | DCP1B | 0.08 | 0.00 | blup | 553 | 0.04 | 1.8e-05 | 4.9 | -6.0 | 2.1e-09 | -0.30 | 0.08 | 0.16 | TRUE |