[Hub]/) : Traits : Breast Cancer : ← →

chr2:24,324,172-25,889,403

Best TWAS P=3.27e-12 · Best GWAS P=1.02e-11 conditioned to 0.27

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ADCY3 0.16 0.12 lasso 10 0.14 3.2e-17 6.1 -6.0 1.4e-09 -0.78 0.13 0.87 FALSE
2 CommonMind Brain Pre-frontal Cortex CENPO 0.07 0.03 bslmm 322 0.03 7.0e-05 3.3 -5.3 1.0e-07 -0.54 0.44 0.32 FALSE
3 GTEx Adipose Subcutaneous ADCY3 0.07 0.04 lasso 6 0.01 3.2e-02 6.8 6.3 2.2e-10 0.96 0.01 0.99 FALSE
4 GTEx Artery Tibial ADCY3 0.21 0.14 lasso 6 0.15 4.3e-12 6.4 6.7 2.9e-11 0.84 0.03 0.97 FALSE
5 GTEx Artery Tibial RP11-443B20.1 0.17 0.08 enet 40 0.09 8.2e-08 6.4 6.3 3.1e-10 0.65 0.03 0.96 FALSE
6 GTEx Cells EBV-transformed lymphocytes ADCY3 0.25 0.23 enet 10 0.12 9.2e-05 6.8 -6.0 2.3e-09 -0.90 0.00 0.99 FALSE
7 GTEx Cells EBV-transformed lymphocytes RP11-443B20.1 0.13 0.13 enet 9 0.05 9.2e-03 6.8 -6.5 8.8e-11 -0.95 0.01 0.97 FALSE
8 GTEx Nerve Tibial ADCY3 0.09 0.05 enet 6 0.03 2.2e-03 6.4 -7.0 3.3e-12 -0.91 0.03 0.97 TRUE
9 GTEx Nerve Tibial RP11-443B20.1 0.07 0.03 enet 6 0.02 1.1e-02 6.4 -6.8 1.1e-11 -0.88 0.03 0.96 FALSE
10 GTEx Whole Blood DNAJC27 0.08 0.10 lasso 1 0.10 2.2e-09 6.4 6.4 1.5e-10 0.95 0.02 0.98 FALSE
11 GTEx Whole Blood ADCY3 0.23 0.24 enet 24 0.27 5.5e-25 6.1 6.6 4.3e-11 0.95 0.02 0.98 FALSE
12 GTEx Whole Blood RP11-443B20.1 0.21 0.17 enet 32 0.20 1.8e-18 6.4 6.7 2.5e-11 0.93 0.02 0.98 FALSE
13 ROSMAP Brain Pre-frontal Cortex ADCY3 0.17 0.26 enet 32 0.26 6.8e-33 6.1 -6.6 4.6e-11 -0.91 0.04 0.96 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma ADCY3 0.03 0.02 blup 81 0.02 7.1e-04 4.1 -5.8 5.0e-09 -0.89 0.03 0.94 FALSE