Hub : Genes

DNAJC27

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1400 0.0380 5.0e-12 0.145 0.108 0.122 0.119 0.138 2.7e-17 5.0e-13 1.2e-14 2.9e-14 2.0e-16
2 GTEx Artery Coronary 0.1170 0.0470 3.9e-03 0.030 NA -0.008 NA 0.003 3.4e-02 NA 8.8e-01 NA 2.5e-01
3 GTEx Cells Transformed fibroblasts 0.1270 0.0510 1.4e-03 0.000 NA -0.003 NA -0.001 3.3e-01 NA 6.4e-01 NA 3.9e-01
4 GTEx Whole Blood 0.0810 0.0330 1.6e-04 0.105 NA 0.087 NA 0.099 7.1e-10 NA 2.0e-08 NA 2.2e-09
5 ROSMAP Brain Pre-frontal Cortex 0.0954 0.0298 4.9e-07 0.059 0.060 0.047 0.057 0.049 4.5e-08 3.7e-08 1.0e-06 8.4e-08 5.7e-07
6 YFS Blood 0.0689 0.0192 3.9e-16 0.045 0.054 0.047 NA 0.043 1.7e-14 3.1e-17 3.7e-15 NA 4.7e-14
7 TCGA Breast Invasive Carcinoma 0.0368 0.0193 2.1e-04 0.007 0.012 0.019 NA 0.015 1.1e-02 1.1e-03 6.7e-05 NA 3.2e-04
8 TCGA Kidney Renal Clear Cell Carcinoma 0.0713 0.0416 8.3e-05 0.017 0.033 0.013 NA 0.015 4.4e-03 1.2e-04 1.2e-02 NA 7.6e-03
9 TCGA Lung Adenocarcinoma 0.0455 0.0221 2.6e-06 0.014 0.037 0.033 NA 0.022 7.2e-03 3.2e-05 9.5e-05 NA 1.2e-03
10 TCGA Ovarian Serous Cystadenocarcinoma 0.0350 0.0220 6.5e-03 0.038 0.011 0.004 NA 0.022 1.2e-03 5.7e-02 1.6e-01 NA 1.2e-02
11 TCGA Pancreatic Adenocarcinoma 0.1190 0.0640 4.7e-05 0.117 0.084 0.044 NA 0.087 1.3e-05 2.1e-04 6.1e-03 NA 1.7e-04
12 TCGA Pheochromocytoma and Paraganglioma 0.0740 0.0480 4.9e-03 0.092 0.077 0.095 NA 0.101 1.6e-04 5.6e-04 1.3e-04 NA 8.2e-05
13 TCGA Prostate Adenocarcinoma 0.0748 0.0374 8.9e-06 0.032 0.049 0.057 NA 0.053 2.5e-04 6.3e-06 1.3e-06 NA 2.7e-06
14 TCGA Stomach Adenocarcinoma 0.1090 0.0740 4.4e-03 0.013 0.019 0.009 NA 0.003 3.6e-02 1.4e-02 6.9e-02 NA 2.0e-01
15 TCGA Thyroid Carcinoma 0.0700 0.0470 2.2e-03 0.012 0.027 0.041 NA 0.033 2.0e-02 1.1e-03 6.8e-05 NA 3.5e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bipolar Disorder (2018) 2.8 4.4 6.7 1.8 -1.7 1.7 0.6 1.9 2.6 2.5 2.2 2.3 1.8 1.8 1.8 2.6 2.6 2.6
Bipolar Disorder or Schizophrenia 0.4 0.9 6.0 -0.1 -0.4 2.5 0.6 0.5 1.5 1.4 0.1 0.5 -0.2 -0.1 -0.1 1.0 0.2 1.2
Depressed Affect (Nagel 2018) 2.6 5.4 8.3 -2.3 2.6 -1.8 2.0 -2.7 -2.4 -2.4 -1.9 -2.9 -2.3 -2.3 -2.3 -2.5 -2.0 -2.4
Depression (Nagel 2018) 3.8 5.7 14.4 -2.4 2.7 -0.1 1.7 -3.8 -1.9 -2.5 -2.1 -2.7 -2.3 -2.3 -2.3 -2.6 -1.9 -2.6
Intelligence (Savage-Jansen 2018) 0.5 1.4 8.1 -1.0 1.9 -0.0 2.8 -0.3 -1.4 -0.2 0.4 -1.7 -0.9 -1.0 -1.0 -0.4 0.8 0.1
Neuroticism (Nagel 2018) 1.9 4.4 7.6 -2.4 2.4 -0.2 1.5 -2.8 -1.7 -1.5 -2.3 -2.5 -2.4 -2.4 -2.4 -1.9 -2.3 -1.8
Schizophrenia (2018) 0.8 1.6 3.5 -1.7 0.8 1.7 0.3 -0.9 -0.2 -0.2 -1.7 -1.2 -1.7 -1.7 -1.7 -0.8 -1.9 -0.5
Schizophrenia vs Biploar Disorder 0.7 0.9 2.2 -1.2 0.5 1.1 -0.1 -1.0 -0.7 -0.2 -1.1 -1.1 -1.1 -1.1 -1.1 -0.6 -1.5 -0.4
Worry (Nagel 2018) 0.4 0.9 2.6 -1.0 0.6 1.1 -1.0 -1.3 -0.2 0.0 -1.6 -0.4 -1.1 -1.0 -1.0 -0.4 -1.2 -0.4
Alzheimer’s Disease (in mother) 0.1 0.1 0.4 -0.3 0.3 -0.0 0.3 -0.1 -0.1 0.6 0.2 -0.1 -0.2 -0.2 -0.2 0.3 0.1 0.5
Alzheimer’s Disease (in father) 2.6 2.8 5.6 -2.4 1.9 0.0 0.6 -1.6 -0.9 -0.6 -1.6 -2.2 -2.4 -2.4 -2.4 -1.6 -1.3 -0.8
Alzheimer’s Disease (including proxy) 0.3 0.4 1.0 -1.0 0.8 0.6 0.1 -0.5 0.1 0.6 -0.3 -0.8 -1.0 -0.8 -0.9 0.1 -0.5 0.4
Crohns Disease (2017) 2.3 5.0 23.3 1.2 0.0 1.6 4.8 1.3 1.5 1.4 3.9 -0.7 1.4 1.2 1.2 1.6 3.9 2.0
Irritable Bowel Disease (IBD) 2.7 6.4 25.2 1.9 -0.9 1.4 5.0 2.2 1.8 1.4 4.2 -0.2 2.1 1.8 1.8 2.0 4.1 2.2
Ulcerative Colitis (UC) 1.2 2.2 11.0 1.3 -1.1 0.4 3.3 1.3 0.9 0.4 2.4 -0.2 1.3 1.1 1.1 0.9 2.2 1.0
Major Depression (MDD) 1.0 1.3 3.2 1.0 -0.5 0.7 1.2 0.9 0.7 1.1 1.8 0.5 1.0 1.1 1.1 1.2 1.8 1.4
Reaction Time 1.1 2.1 11.6 1.2 -2.0 -0.2 -3.4 1.3 0.1 0.6 -0.3 2.1 1.3 1.3 1.3 0.8 -1.1 0.5
Verbal and Numeric Reasoning (VNR) 1.1 2.6 11.4 -1.4 2.4 -0.8 3.4 -1.3 -1.6 -0.9 -0.0 -2.2 -1.4 -1.4 -1.4 -1.1 0.9 -0.6
Breast Cancer 2.4 5.7 41.0 -0.5 2.2 -2.0 6.4 -2.0 -2.6 -2.3 0.9 -3.2 -0.6 -0.6 -0.6 -1.6 1.6 -1.6
Ovarian Cancer 2.1 2.8 5.9 -1.7 1.7 -0.7 -0.8 -2.4 -1.6 -1.6 -2.2 -0.9 -1.8 -1.8 -1.8 -1.7 -1.7 -1.8
Prostate Cancer 1.2 1.7 3.5 1.4 -1.4 0.6 1.0 0.5 1.2 1.0 1.9 0.9 1.5 1.5 1.5 1.3 1.8 1.3
Age at First Birth 0.6 0.9 2.0 -1.2 1.2 0.8 -0.1 -1.1 0.1 -0.3 -1.2 -1.0 -1.4 -1.1 -1.1 -0.8 -0.6 -0.5
Bipolar Disorder (2011) 0.1 0.1 0.4 -0.1 0.2 0.7 -0.5 0.2 0.2 -0.1 -0.2 0.3 -0.2 -0.0 -0.0 -0.1 0.1 -0.2
Body Mass Index (BMI) (2010) 2.3 3.2 20.4 -1.2 1.7 -0.5 4.5 -1.8 -0.7 -1.5 0.6 -2.9 -1.3 -1.3 -1.3 -1.5 0.5 -1.0
Coronary Artery Disease (CAD) 1.1 1.4 2.4 1.3 -0.9 -0.3 -0.2 1.5 1.5 1.3 1.4 0.9 1.1 0.8 0.9 1.2 1.5 1.4
Crohns Disease (2012) 1.6 2.6 7.3 0.9 -0.2 2.5 2.1 0.8 1.5 1.8 2.7 0.2 0.9 0.9 0.9 1.7 2.2 2.0
Mean Putamen Volume 0.4 0.4 1.8 -0.2 -0.4 -1.1 -0.2 -0.4 0.1 -1.3 -0.5 -0.1 -0.1 -0.1 -0.1 -1.0 -0.4 -1.2
Fasting Glucose 1.0 1.2 4.8 -1.2 1.0 2.2 0.6 -1.9 -0.1 0.4 -0.5 -1.3 -1.3 -1.2 -1.2 -0.4 0.2 0.3
HbA1C 0.2 0.2 1.1 0.3 -0.1 0.3 0.4 -0.3 -0.9 -0.0 0.9 -0.1 0.1 0.1 0.1 -0.0 1.1 0.2
HDL Cholesterol 0.8 1.3 6.0 -0.2 -0.4 -1.0 -2.0 -1.0 -1.0 -1.2 -1.3 0.2 -0.1 -0.1 -0.1 -0.8 -2.4 -1.3
LDL Cholesterol 0.1 0.1 0.4 -0.1 0.6 0.1 -0.0 0.2 -0.2 -0.5 0.1 -0.3 0.0 0.5 0.5 -0.1 0.4 -0.3
Lupus 1.2 1.8 3.0 -1.4 1.2 -0.2 -0.8 -1.3 -1.2 -1.0 -1.7 -0.8 -1.7 -1.7 -1.7 -1.3 -1.7 -1.2
Neuroticism (2016) 0.8 1.1 3.0 0.9 -1.2 1.5 -0.7 0.0 1.7 1.2 0.5 1.2 0.9 0.8 0.8 1.4 0.0 1.1
Primary Biliary Cirrhosis 0.8 1.1 4.7 0.5 0.5 1.6 2.2 -0.1 0.4 1.1 1.5 0.0 0.5 0.5 0.5 1.2 1.1 1.2
Rheumatoid Arthritis 0.4 0.5 2.7 0.1 0.4 1.6 1.2 -1.1 0.7 -0.2 0.7 -0.7 0.2 0.2 0.2 -0.1 0.4 0.1
Schizophrenia (2014) 0.3 0.7 5.1 -0.5 -0.1 2.2 0.2 0.7 1.1 1.1 -0.5 0.1 -0.6 -0.6 -0.6 0.5 -0.8 0.7
Triglycerides 0.6 1.0 2.5 0.7 -0.4 1.6 -0.5 0.2 1.5 1.4 0.8 1.0 0.5 0.6 0.6 1.2 1.4 1.2
Type 2 Diabetes (T2D) (2012) 1.2 1.4 2.4 -1.0 0.7 -0.1 0.1 -1.4 -1.2 -1.0 -1.6 -0.9 -1.3 -1.5 -1.5 -1.3 -1.2 -1.2
Ulcerative Colitis 0.7 1.0 9.5 0.0 0.4 0.8 3.1 0.9 0.7 0.1 0.9 -1.1 -0.1 -0.2 -0.2 0.0 1.0 0.4
Blood Eosinophil Count 0.3 2.4 17.0 0.5 0.3 -2.2 4.1 1.2 1.3 0.1 1.6 -0.7 0.5 0.5 0.5 0.4 2.6 0.5
Blood Platelet Count 0.1 1.5 4.7 -1.3 2.1 0.4 2.2 -1.9 0.3 0.7 -0.3 -1.7 -1.3 -1.3 -1.3 -0.1 -0.1 0.5
Blood Red Count 0.5 4.5 9.2 2.5 -2.0 -0.1 -0.2 2.3 1.8 1.3 2.3 2.8 2.5 2.5 2.5 2.1 3.0 1.6
Blood White Count 0.6 4.3 10.2 2.2 -1.7 -1.5 3.1 1.4 1.8 0.4 3.2 1.0 2.3 2.3 2.3 1.5 3.0 1.1
Heel T-Score 1.6 12.5 20.6 -3.4 3.6 -1.8 3.0 -4.3 -3.8 -3.7 -3.1 -4.5 -3.2 -3.2 -3.2 -3.9 -3.5 -3.7
BMI 7.9 46.1 269.0 -5.1 8.2 -1.8 16.4 -5.1 -5.5 -5.6 0.6 -10.4 -5.2 -5.2 -5.2 -5.5 1.8 -4.1
Height 4.9 95.3 412.1 8.3 -12.4 2.1 -20.3 10.7 7.6 7.4 0.8 16.0 8.3 8.3 8.3 8.1 -0.8 5.9
Waist Hip Ratio (WHR) 2.5 11.1 27.0 3.1 -3.4 1.9 -2.8 3.7 3.2 4.0 1.8 5.2 3.1 3.1 3.1 4.4 2.0 3.5
Systolic Blood Pressure 3.8 19.1 60.4 3.7 -5.0 2.1 -7.8 3.5 3.7 4.6 1.2 7.3 3.8 3.8 3.8 4.7 1.2 3.9
Smoking Status 0.7 1.8 14.1 -0.6 0.7 -0.8 3.8 -0.5 -1.1 -1.4 0.4 -2.0 -0.6 -0.6 -0.6 -1.2 -0.0 -1.0
Allergy or Eczema 1.9 4.9 9.9 -2.7 2.4 -1.2 1.3 -1.0 -2.1 -1.4 -2.4 -2.5 -2.7 -2.7 -2.7 -2.0 -3.1 -1.7
Cardiovascular Disease 0.4 1.3 5.5 0.7 -0.6 0.0 -1.5 1.1 0.3 1.7 0.4 2.3 0.8 0.8 0.8 1.7 0.7 1.4
Hypothyroidism (self reported) 0.4 0.8 3.2 0.4 -0.4 1.4 1.8 -0.8 0.4 0.2 1.3 -0.3 0.5 0.5 0.5 0.4 1.7 0.5
Respiratory disease 0.5 1.1 2.8 -1.4 1.1 -1.7 1.3 -0.4 -0.5 0.2 -0.7 -1.3 -1.5 -1.4 -1.4 -0.5 -0.3 0.1
Type 2 Diabetes (T2D) (2018) 1.6 2.9 6.2 -2.4 2.5 1.0 1.3 -1.9 -0.6 -0.4 -1.5 -1.9 -2.4 -2.4 -2.4 -1.3 -0.6 -0.5
Lung FEV1/FVC ratio 1.0 5.0 42.4 0.4 1.1 2.1 6.5 -0.3 0.7 1.1 2.9 -1.5 0.4 0.4 0.4 1.2 3.2 1.7
Lung FVC 0.5 2.3 9.1 1.0 -1.5 -2.3 -3.0 -0.2 0.2 -1.1 -1.2 2.0 1.0 1.0 1.0 -0.2 -2.4 -1.2
Neuroticism 2.9 7.0 10.8 -3.0 3.3 -0.7 1.6 -2.7 -2.7 -2.3 -2.7 -3.0 -3.0 -3.0 -3.0 -2.6 -2.4 -2.6
Chronotype (morning person) 3.0 7.0 14.7 2.4 -3.0 2.2 -3.8 1.4 3.0 3.2 1.3 3.8 2.3 2.3 2.3 3.0 1.1 2.8
Hair Pigment 0.1 3.6 18.7 0.8 1.3 1.5 4.3 1.1 2.5 1.1 2.8 -0.9 0.7 0.8 0.8 1.4 2.6 1.5
Tanning 3.0 36.4 60.8 6.4 -7.8 1.0 -5.5 6.9 6.1 5.6 4.8 7.5 6.5 6.5 6.5 6.2 4.7 5.7
Hand grip strength (left) 2.2 5.8 51.1 0.0 -1.4 -1.1 -7.2 0.2 -0.8 -1.2 -2.8 2.2 0.0 0.0 0.0 -1.0 -3.7 -1.9
Number of treatments/medications taken 0.3 0.6 1.6 0.4 -0.4 1.3 -0.2 0.4 0.5 1.2 0.9 0.8 0.4 0.4 0.4 1.2 -0.0 1.2
Average weekly spirits intake 0.7 0.8 4.3 0.2 0.1 1.6 -0.6 0.8 2.1 0.8 1.0 0.2 0.2 0.2 0.2 0.5 1.1 0.9
Sensitivity / hurt feelings 1.0 1.6 4.5 -1.4 2.1 1.0 2.0 -1.6 -0.5 -0.5 -0.4 -1.9 -1.3 -1.3 -1.3 -0.8 -0.0 -0.5
Frequency of depressed mood in last 2 weeks 1.5 2.1 6.2 -1.3 1.2 -0.6 1.8 -2.5 -1.5 -1.7 -0.9 -1.6 -1.2 -1.2 -1.2 -1.5 -0.7 -1.5
Hearing difficulty/problems: Yes 1.2 1.8 5.2 -1.5 1.6 1.2 2.3 -1.1 -1.1 -0.2 -0.8 -1.8 -1.6 -1.6 -1.6 -0.7 -0.4 -0.3
Relative age of first facial hair 0.3 0.7 3.2 -0.5 1.4 0.4 1.8 -0.3 -1.1 0.6 0.2 -1.2 -0.7 -0.7 -0.7 0.4 -0.5 0.5
Other serious medical condition/disability diagnosed by doctor 3.2 4.2 7.6 2.0 -1.6 1.9 -0.5 1.9 1.3 2.5 2.4 2.1 2.0 2.0 2.0 2.8 1.9 2.5
Ever used hormone-replacement therapy (HRT) 0.2 0.2 1.2 -0.0 -0.4 -0.4 -1.1 0.6 -0.4 0.5 -0.4 0.6 -0.0 -0.0 -0.0 0.4 -0.6 0.3
Ever had hysterectomy (womb removed) 0.1 0.2 0.8 0.4 -0.9 -0.4 -0.3 0.4 0.5 -0.3 -0.0 0.6 0.3 0.3 0.4 -0.0 -0.3 -0.1
Systolic blood pressure, automated reading 1.2 3.6 12.8 1.4 -1.7 0.5 -3.4 1.6 1.5 2.3 0.2 3.6 1.4 1.4 1.4 2.3 0.3 1.8
Eye problems/disorders: Diabetes related eye disease 4.9 5.4 8.2 -2.7 2.9 -0.9 1.9 -2.6 -1.2 -2.1 -2.2 -2.7 -2.7 -2.7 -2.7 -2.6 -1.7 -2.2
Angina 1.6 2.1 6.9 1.6 -1.0 0.6 1.2 1.0 0.5 1.0 2.6 0.5 1.6 1.6 1.6 1.4 2.2 1.4
Medication for hormone replacement therapy 1.2 1.3 6.1 -1.2 0.8 0.0 -1.4 -0.5 -0.8 -0.4 -1.6 -0.6 -1.2 -1.3 -1.3 -0.8 -2.5 -0.8
Vitamin and mineral supplements 0.4 0.5 2.7 -0.6 1.2 0.4 1.6 -0.2 -0.1 0.0 0.2 -1.0 -0.6 -0.6 -0.6 -0.2 1.1 0.0
Supplements: Zinc 0.4 0.4 1.6 -0.7 0.6 0.1 -0.6 -0.1 0.1 -0.4 -0.9 -0.5 -0.7 -0.7 -0.7 -0.5 -1.2 -0.5
Medication: Co-codamol 1.0 1.2 2.1 0.9 -1.3 0.0 1.4 0.2 1.4 1.0 1.5 0.6 1.0 1.0 1.0 1.2 1.4 1.2
Medication: Metformin 3.0 4.2 7.8 -2.7 2.8 -0.9 2.3 -1.8 -0.5 -1.1 -1.6 -2.7 -2.7 -2.7 -2.7 -1.9 -0.4 -1.2
Diabetes (father) 0.5 0.7 3.2 0.5 -1.3 0.9 -1.2 -1.8 0.0 0.5 0.4 0.9 0.5 0.5 0.5 0.5 0.4 0.5
Diabetes (mother) 0.4 0.5 2.6 -0.7 0.3 -0.0 -0.5 -0.0 0.6 1.6 -0.3 0.2 -0.7 -0.7 -0.7 0.6 0.5 1.4
Severe depression (siblings) 0.4 0.4 2.5 0.0 -0.1 0.2 1.6 -0.4 0.6 -0.0 0.8 -0.5 0.0 0.0 0.0 -0.1 1.4 0.3
Pack years adult smoking proportion 0.8 1.3 5.3 -0.8 1.2 1.6 2.3 -1.2 -0.5 -1.0 0.1 -1.6 -0.8 -0.8 -0.8 -0.9 0.1 -0.7
Impedance of leg (right) 2.7 13.0 35.0 3.0 -3.9 2.2 -5.9 3.7 3.6 4.4 1.1 5.2 2.9 3.0 3.0 4.1 0.5 3.7
Leg fat-free mass (left) 0.5 2.5 7.4 -1.1 1.1 -1.6 1.8 -0.6 -2.2 -2.7 -0.7 -1.5 -1.0 -1.0 -1.0 -2.3 -0.1 -2.3
Trunk fat percentage 3.6 14.4 108.2 -2.4 4.3 -0.7 10.4 -2.0 -2.8 -2.9 1.2 -5.4 -2.4 -2.4 -2.4 -2.6 2.0 -2.0
Hand grip strength (right) 2.1 5.6 44.2 -0.3 -1.2 -1.2 -6.7 -0.4 -0.8 -1.8 -2.9 1.7 -0.3 -0.3 -0.3 -1.6 -3.6 -2.2
Townsend deprivation index at recruitment 0.2 0.3 0.7 -0.8 0.4 0.2 0.8 -0.5 -0.3 -0.4 -0.3 -0.6 -0.8 -0.8 -0.8 -0.5 -0.1 -0.3
Current tobacco smoking 0.4 0.7 3.5 0.8 -0.6 -0.6 1.9 0.4 -0.3 -0.8 1.1 -0.2 0.7 0.7 0.7 -0.2 1.2 -0.3
Average weekly fortified wine intake 0.8 1.0 2.4 -1.2 1.2 1.0 0.5 -1.5 0.0 -0.5 -0.6 -1.3 -1.2 -1.2 -1.2 -0.8 -0.7 -0.6
Maternal smoking around birth 0.5 0.7 1.6 -1.2 1.2 0.2 0.2 0.3 -0.3 0.1 -0.8 -0.9 -1.2 -1.2 -1.2 -0.4 -0.6 -0.1
Fed-up feelings 3.5 6.4 9.7 -3.0 2.9 -1.1 1.7 -2.0 -2.8 -2.1 -2.4 -3.1 -2.9 -2.9 -2.9 -2.6 -2.2 -2.3
Frequency of unenthusiasm / disinterest in last 2 weeks 3.5 4.7 12.7 -2.0 2.0 -0.3 1.1 -3.6 -1.5 -2.8 -2.0 -2.3 -1.9 -1.9 -1.9 -2.6 -1.8 -2.8
Relative age voice broke 0.5 0.7 3.0 -0.3 0.8 0.7 1.7 -1.5 -1.1 -0.4 -0.2 -0.9 -0.4 -0.4 -0.4 -0.1 -1.2 -0.4
Taking other prescription medications 0.7 1.1 3.7 -0.2 -0.0 1.5 0.9 -0.0 1.6 1.9 1.0 0.1 -0.2 -0.2 -0.2 1.3 1.0 1.8
Age when periods started (menarche) 1.5 3.6 19.9 -0.3 -0.7 -0.9 -4.5 -0.5 -1.1 -1.2 -2.7 1.3 -0.2 -0.2 -0.2 -0.9 -4.2 -1.7
Bilateral oophorectomy (both ovaries removed) 0.4 0.4 1.6 0.6 -0.8 -0.3 -1.2 0.9 -0.0 0.2 0.1 1.3 0.6 0.6 0.6 0.4 0.3 0.2
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.4 2.6 -1.5 1.4 1.2 0.4 -1.6 -1.6 0.2 -0.4 -1.5 -1.4 -1.4 -1.4 -0.4 -1.3 -0.1
Tinnitus: Yes, but not now, but have in the past 2.0 2.1 4.2 -1.7 1.7 -0.7 -0.4 -1.0 -2.0 -1.3 -1.4 -1.5 -1.7 -1.7 -1.7 -1.8 -0.7 -1.4
Qualifications: CSEs or equivalent 0.6 0.7 3.3 0.7 -0.5 1.0 0.7 -0.4 1.3 0.4 1.0 0.4 0.8 0.8 0.8 0.4 1.8 0.7
Serious illness, injury or assault to yourself 1.6 1.9 7.2 0.6 -0.4 1.4 -0.8 1.5 0.8 2.7 1.4 1.0 0.6 0.6 0.6 2.0 1.1 2.5
High blood pressure 0.5 1.4 6.1 0.9 -0.6 -0.8 -1.9 1.1 0.2 1.4 0.3 2.5 0.8 0.8 0.8 1.5 0.7 1.2
Hayfever, allergic rhinitis or eczema 1.6 3.6 9.4 -2.3 1.9 -0.6 0.8 -0.8 -1.5 -1.2 -2.1 -2.1 -2.3 -2.3 -2.3 -1.6 -3.1 -1.5
Multivitamins +/- minerals 0.4 0.5 4.4 0.1 -0.7 -0.4 -2.1 0.3 0.0 0.3 -0.4 0.7 0.2 0.2 0.2 0.2 -1.1 0.1
Stomach or abdominal pain in last month 0.7 0.9 1.5 -0.9 1.0 -0.7 -0.7 -0.9 -0.7 -1.1 -1.1 -0.8 -0.9 -0.9 -0.9 -1.1 -1.0 -1.2
Supplements: Glucosamine 0.5 0.6 2.5 0.6 -1.0 -1.6 -0.2 0.1 -0.7 -1.4 0.1 0.3 0.6 0.6 0.6 -0.7 -0.5 -1.1
Diverticular disease/diverticulitis (self-reported) 1.1 1.3 2.5 1.3 -1.3 -0.7 -0.5 1.6 1.2 1.1 0.7 1.4 1.2 1.2 1.2 1.3 0.6 1.1
Medication: Atenolol 0.6 0.8 4.0 -0.8 1.0 -0.6 0.5 -1.1 -2.0 -0.7 -0.6 -0.3 -0.7 -0.7 -0.7 -0.5 -0.9 -0.6
Medication: Levothyroxine sodium 0.6 0.9 1.9 0.7 -0.9 1.1 1.0 0.1 0.8 1.3 1.2 0.3 0.7 0.7 0.7 1.2 1.4 1.4
Sitting height 2.6 18.1 171.6 1.8 -4.7 0.5 -13.1 2.8 1.4 1.4 -2.8 5.9 1.8 1.8 1.8 0.9 -3.1 0.4
Chronic bronchitis/emphysema (father) 0.3 0.4 0.7 -0.6 0.8 -0.6 0.2 -0.3 -0.2 -0.6 -0.9 -0.6 -0.6 -0.6 -0.6 -0.7 -0.7 -0.7
High blood pressure (mother) 1.1 1.6 3.5 1.6 -1.6 -0.6 -0.8 0.9 1.2 0.6 1.1 1.9 1.5 1.5 1.5 1.1 1.2 0.7
Body mass index (BMI) 7.4 31.4 169.0 -4.1 6.6 -2.4 13.0 -4.5 -5.1 -5.1 0.4 -8.4 -4.2 -4.2 -4.2 -4.8 1.7 -3.8
Impedance of leg (left) 2.5 12.2 31.1 3.1 -4.1 1.8 -5.6 3.5 3.7 4.0 1.1 5.1 3.0 3.1 3.0 3.8 0.5 3.4
Leg predicted mass (left) 0.4 2.3 7.1 -1.0 1.1 -1.6 1.8 -0.5 -2.1 -2.7 -0.6 -1.4 -0.9 -0.9 -0.9 -2.2 -0.0 -2.2
Trunk fat mass 2.7 11.6 77.6 -2.2 3.8 -1.0 8.8 -1.9 -3.0 -3.2 0.7 -4.7 -2.3 -2.3 -2.3 -2.8 1.5 -2.3
Waist circumference 2.5 9.0 69.9 -1.6 3.3 -0.8 8.4 -1.4 -2.6 -2.4 1.2 -4.0 -1.6 -1.6 -1.6 -1.9 2.2 -1.6
Number of incorrect matches in round 0.7 1.2 9.7 0.3 -1.3 -0.3 -3.1 0.2 0.6 -0.1 -1.1 1.3 0.2 0.2 0.2 -0.0 -1.6 -0.3
Past tobacco smoking 2.2 4.0 16.8 1.7 -1.9 0.2 -4.1 1.7 2.4 2.0 0.7 2.7 1.7 1.7 1.7 2.0 1.0 1.6
Alcohol usually taken with meals 1.3 2.0 3.9 1.6 -2.0 0.9 -1.4 1.4 0.2 1.2 1.3 1.8 1.6 1.6 1.6 1.4 1.4 1.3
Nervous feelings 0.6 1.1 2.1 -1.4 0.9 1.3 -1.0 -0.9 0.1 0.2 -1.4 -0.8 -1.3 -1.3 -1.3 -0.4 -1.4 -0.2
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.4 0.9 0.7 -0.9 -0.3 0.5 -0.2 0.8 -0.2 0.4 0.7 0.8 0.8 0.8 0.3 0.5 -0.1
Hearing difficulty/problems with background noise 1.7 2.6 5.2 -2.2 1.4 1.0 1.4 -1.6 -1.3 -0.5 -1.8 -1.7 -2.3 -2.3 -2.3 -1.3 -1.3 -0.8
Hair/balding pattern: Pattern 2 0.6 0.8 2.2 1.3 -0.8 -0.2 0.6 0.4 0.2 0.0 1.1 0.7 1.3 1.3 1.3 0.6 1.5 0.3
Had menopause 0.8 1.0 2.8 0.7 -1.2 0.8 -0.9 0.8 0.5 1.7 0.5 1.4 0.7 0.7 0.7 1.5 0.1 1.5
Had other major operations 0.1 0.1 0.8 0.1 0.1 -0.2 0.2 0.9 -0.6 0.1 0.3 -0.0 0.1 0.0 0.0 0.2 0.0 0.2
Forced vital capacity (FVC) 2.9 11.2 76.0 2.3 -4.0 -0.5 -8.7 2.6 1.3 1.2 -1.4 5.6 2.4 2.4 2.4 1.7 -2.7 0.6
Heel bone mineral density (BMD) T-score, automated (right) 0.0 0.1 0.4 -0.1 -0.0 -0.1 0.4 -0.6 -0.5 -0.1 0.4 -0.3 0.1 0.1 0.1 -0.1 0.2 -0.0
Ever unenthusiastic/disinterested for a whole week 2.3 2.8 5.2 -1.8 1.9 -1.6 1.5 -0.6 -1.0 -2.0 -1.4 -2.3 -1.7 -1.7 -1.7 -2.1 -1.1 -1.9
Qualifications: None of the above 0.1 0.2 0.7 0.3 -0.4 0.0 0.5 0.1 -0.3 -0.7 -0.1 -0.2 0.2 0.2 0.2 -0.3 -0.8 -0.6
Financial difficulties in last 2 years 1.1 1.4 3.9 -1.2 1.0 -1.1 1.0 -2.0 -1.0 -1.4 -0.9 -1.3 -1.1 -1.1 -1.1 -1.4 -0.7 -1.3
Mouth/teeth dental problems 1.7 2.6 8.4 1.9 -2.1 0.5 -2.9 1.2 0.3 0.9 1.0 2.2 1.9 1.9 1.9 1.3 0.4 0.9
Heart attack 1.2 1.6 3.5 1.9 -1.4 0.0 -0.2 0.9 0.9 0.3 1.8 1.0 1.8 1.8 1.8 1.0 0.8 0.6
Allergy 0.4 0.9 1.9 1.4 -0.9 -0.1 -0.6 0.5 0.5 -0.1 0.9 1.1 1.3 1.3 1.3 0.4 1.4 0.1
Pain all over the body in last month 0.9 1.0 3.3 -0.9 0.2 -0.6 -0.8 -0.5 -1.1 -1.1 -1.4 -0.4 -0.9 -0.9 -0.9 -1.2 -1.8 -1.1
Diabetes (self-reported) 5.8 8.9 14.7 -3.7 3.8 -0.1 1.8 -3.4 -1.9 -2.0 -2.9 -3.6 -3.8 -3.8 -3.8 -2.9 -2.1 -2.2
Hayfever/allergic rhinitis (self-reported) 3.0 3.9 9.5 -2.1 1.7 0.0 -1.0 -1.6 -2.1 -1.8 -2.5 -1.4 -2.2 -2.2 -2.2 -2.1 -3.1 -2.1
Medication: Ramipril 0.2 0.3 1.3 -0.4 0.4 -0.8 -1.1 -0.4 -0.9 -0.1 -0.5 0.5 -0.4 -0.4 -0.4 -0.2 -0.3 -0.2
Medication: Simvastatin 0.1 0.2 0.8 -0.6 0.9 -0.1 0.9 -0.1 0.1 0.1 0.1 -0.5 -0.5 -0.5 -0.5 -0.0 0.4 -0.0
Fluid intelligence score 2.1 4.5 9.7 -2.5 3.1 -0.3 3.0 -1.7 -2.0 -1.2 -1.0 -3.1 -2.4 -2.4 -2.4 -1.8 -0.4 -1.1
Illnesses of siblings 0.7 1.0 2.2 -0.5 0.3 -0.8 -1.5 -0.2 -1.3 -1.2 -1.3 -0.4 -0.5 -0.5 -0.5 -1.3 -1.3 -1.3
Neuroticism score 2.6 5.5 8.2 -2.6 2.8 0.2 2.3 -2.7 -2.1 -2.2 -2.1 -2.9 -2.6 -2.6 -2.6 -2.5 -1.6 -2.2
Weight 1.3 6.2 33.2 -1.5 2.5 -1.7 5.8 -1.3 -2.9 -3.1 0.3 -3.1 -1.5 -1.5 -1.5 -2.5 1.0 -2.3
Impedance of arm (right) 0.9 4.2 8.2 1.7 -2.2 2.3 -2.4 2.2 2.7 2.4 0.7 2.9 1.6 1.6 1.6 2.3 0.6 2.1
Arm fat percentage (right) 7.9 31.2 185.0 -4.2 6.8 -1.2 13.6 -4.1 -4.3 -4.6 0.7 -8.3 -4.3 -4.3 -4.3 -4.5 2.1 -3.4
Trunk fat-free mass 0.4 2.0 13.2 0.2 -0.9 -1.4 -3.6 0.6 -1.4 -1.5 -1.3 1.6 0.3 0.2 0.2 -1.0 -1.2 -1.6
Hip circumference 3.4 14.5 70.1 -2.8 4.2 -1.4 8.4 -2.2 -3.8 -4.1 0.2 -5.7 -2.9 -2.9 -2.9 -3.9 1.2 -3.1
Time employed in main current job 5.8 6.7 13.5 2.9 -3.7 0.6 -2.1 3.0 2.7 2.2 1.9 3.3 2.9 2.9 2.9 2.6 1.3 2.2
Alcohol intake versus 10 years previously 0.2 0.3 1.2 0.3 -1.1 -0.6 0.5 -0.5 -0.2 -0.9 0.2 -0.1 0.3 0.3 0.3 -0.6 0.0 -0.7
Father’s age at death 0.3 0.4 1.7 0.8 -1.2 -1.3 -0.4 0.5 -0.3 -0.0 0.3 0.6 0.8 0.8 0.8 0.4 -0.1 0.0
Worrier / anxious feelings 0.6 1.0 3.6 -1.0 0.3 0.6 -1.9 -0.6 -0.3 -0.2 -1.8 -0.1 -1.0 -1.0 -0.9 -0.6 -1.8 -0.6
Frequency of tiredness / lethargy in last 2 weeks 0.8 1.3 5.3 -1.1 1.2 1.2 2.3 -1.9 -0.7 -0.6 -0.1 -1.3 -1.0 -1.0 -1.0 -0.8 0.5 -0.4
Falls in the last year 0.7 1.0 3.0 0.5 -0.3 0.1 0.1 1.7 1.0 1.6 1.0 0.8 0.5 0.5 0.5 1.4 1.1 1.5
Hair/balding pattern: Pattern 3 0.8 1.2 2.9 -1.0 0.2 -0.4 -1.1 -1.0 -0.6 -1.3 -1.7 -0.5 -1.0 -1.0 -1.0 -1.4 -1.6 -1.5
Number of live births 0.3 0.4 0.8 0.6 -0.7 -0.6 -0.9 0.5 0.3 0.6 0.6 0.9 0.6 0.6 0.6 0.6 0.9 0.5
Forced expiratory volume in 1-second (FEV1) 2.3 7.6 44.0 2.1 -3.2 -0.3 -6.6 2.6 1.4 1.5 -0.6 4.7 2.2 2.2 2.2 1.9 -1.5 1.0
Pulse rate 2.0 3.4 7.2 -2.5 2.3 -0.4 -0.6 -0.7 -1.2 -0.4 -2.5 -1.4 -2.7 -2.7 -2.7 -1.4 -1.9 -0.9
Happiness 0.3 0.4 1.2 0.6 -0.9 -0.7 0.8 0.2 0.7 -0.0 0.6 0.4 0.7 0.7 0.7 0.3 1.1 0.1
Noisy workplace 0.3 0.4 0.7 0.7 -0.8 -0.2 -0.0 0.5 0.4 0.8 0.3 0.8 0.6 0.6 0.6 0.7 0.5 0.7
Qualifications: A levels/AS levels or equivalent 0.2 0.4 4.3 -0.1 0.1 -0.0 -2.1 0.5 0.0 0.4 -0.3 0.6 -0.1 -0.1 -0.1 0.2 -0.2 0.1
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 1.7 0.0 0.5 0.1 1.3 -0.2 -0.3 -0.3 0.3 -0.7 0.1 0.1 0.1 -0.1 -0.5 -0.2
Mouth/teeth dental problems: Dentures 1.0 1.6 11.2 -1.0 1.3 1.1 3.4 -0.8 0.3 0.1 0.7 -1.8 -1.0 -1.1 -1.1 -0.2 1.0 0.3
Asthma 0.3 0.6 1.6 -0.9 0.8 -1.2 1.1 -0.7 0.0 0.5 -0.0 -0.7 -0.9 -0.9 -0.9 -0.1 0.5 0.5
Medication: Ibuprofen (e.g. Nurofen) 0.7 0.9 2.7 0.1 -0.5 -1.1 -1.2 -0.8 -1.6 -1.4 -0.9 0.6 0.1 0.1 0.1 -0.9 -1.2 -1.4
Medication: Cholesterol lowering 0.0 0.1 0.6 -0.1 0.4 0.2 0.0 0.1 -0.8 -0.1 0.1 -0.2 -0.2 -0.2 -0.2 0.0 -0.3 -0.1
Depression (self-reported) 0.1 0.1 1.4 0.1 -0.2 0.0 0.1 -1.2 -0.0 -0.1 -0.1 0.2 0.2 0.2 0.2 0.0 -0.2 -0.1
Medication: Lansoprazole 2.7 3.1 7.7 1.1 -0.4 2.4 0.2 1.0 1.6 2.8 2.0 1.2 1.2 1.2 1.2 2.5 2.2 2.7
Prospective memory result 0.6 0.7 1.3 0.9 -1.1 0.2 -0.4 1.0 1.1 0.8 0.6 1.0 0.9 0.9 0.9 0.9 0.7 0.7
Lung cancer (father) 0.4 0.5 1.9 0.7 -0.9 -0.1 -0.9 0.8 1.4 0.2 0.6 0.7 0.7 0.7 0.7 0.4 0.4 0.4
Illnesses of mother 2.2 2.7 4.2 -1.9 2.0 0.8 -0.3 -1.7 -1.6 -1.2 -1.8 -1.9 -1.8 -1.8 -1.8 -1.8 -1.8 -1.3
Forced expiratory volume in 1-second (FEV1), Best measure 1.8 5.8 28.6 2.1 -3.0 -0.3 -5.3 2.4 1.1 1.1 -0.1 4.2 2.2 2.2 2.2 1.6 -0.9 0.8
Pulse wave Arterial Stiffness index 0.2 0.2 1.3 -0.5 -0.0 -0.3 -0.2 -1.1 0.1 -0.5 -0.4 -0.3 -0.5 -0.5 -0.5 -0.7 -0.3 -0.4
Impedance of arm (left) 1.3 6.2 11.0 2.2 -2.5 2.3 -2.4 3.0 3.0 3.0 1.3 3.3 2.2 2.2 2.2 3.0 0.8 2.6
Arm fat mass (right) 5.2 21.6 116.6 -3.5 5.6 -1.3 10.8 -3.4 -4.2 -4.3 0.3 -6.7 -3.6 -3.6 -3.6 -4.1 1.5 -3.3
Trunk predicted mass 0.4 2.1 13.2 0.2 -0.9 -1.5 -3.6 0.5 -1.4 -1.6 -1.4 1.6 0.2 0.2 0.2 -1.1 -1.3 -1.7
Standing height 4.0 39.9 207.4 5.2 -8.2 1.0 -14.4 6.6 3.8 3.6 -0.4 10.6 5.3 5.3 5.3 4.3 -1.5 2.6
Length of working week for main job 0.5 0.6 1.1 -1.0 0.6 0.1 -0.1 -0.4 -0.6 -1.0 -0.9 -0.6 -0.8 -0.8 -0.8 -1.0 -0.9 -1.1
Exposure to tobacco smoke at home 1.4 1.6 3.9 1.5 -2.0 0.4 -0.3 1.1 1.3 0.4 1.1 1.5 1.6 1.6 1.6 0.8 1.3 0.6
Breastfed as a baby 0.5 0.7 3.2 0.9 -1.8 -0.7 -1.0 -0.4 0.4 -0.5 0.2 1.0 0.9 1.0 1.0 -0.2 0.3 -0.3
Tense / ‘highly strung’ 0.2 0.3 1.5 0.1 -0.3 0.8 -0.7 -0.6 1.2 0.3 -0.4 0.6 0.1 0.1 0.1 0.2 -0.0 0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 1.7 2.7 5.3 -1.9 2.3 -0.2 2.2 -2.1 -0.4 -1.0 -1.3 -2.1 -1.9 -1.9 -1.9 -1.2 -1.1 -1.1
Hair/balding pattern: Pattern 4 0.1 0.4 2.0 -0.1 0.5 1.4 1.2 -0.0 0.5 -0.4 0.3 -0.6 -0.2 -0.2 -0.2 -0.4 0.6 -0.2
Birth weight of first child 0.2 0.4 1.7 -0.2 -0.6 -0.5 -1.3 -0.5 0.1 0.1 -1.1 0.6 -0.3 -0.3 -0.3 -0.1 -1.2 -0.2
Peak expiratory flow (PEF) 1.3 2.9 12.5 1.4 -1.9 -1.0 -3.5 2.6 1.0 1.0 -0.0 2.7 1.4 1.5 1.5 1.2 -0.6 0.7
Pulse wave reflection index 0.2 0.3 1.0 0.3 -1.0 -0.9 0.3 -0.8 -0.1 -0.7 0.5 0.0 0.4 0.4 0.4 -0.5 0.2 -0.4
Ever highly irritable/argumentative for 2 days 0.2 0.2 0.4 0.5 -0.7 -0.5 0.6 0.3 -0.3 0.4 0.4 0.4 0.6 0.6 0.6 0.6 0.3 0.4
Loud music exposure frequency 0.4 0.5 1.1 0.5 -0.9 0.6 -0.8 -0.2 1.1 0.8 -0.0 0.8 0.5 0.5 0.5 0.8 -0.8 0.6
Qualifications: O levels/GCSEs or equivalent 0.2 0.4 2.0 0.3 -0.2 0.7 -1.4 0.2 0.1 0.4 0.3 0.9 0.4 0.4 0.4 0.4 1.0 0.4
Mouth/teeth dental problems: Bleeding gums 0.8 1.0 3.3 -1.3 1.8 -0.3 0.9 -0.7 -0.5 -0.2 -0.9 -1.2 -1.4 -1.4 -1.4 -0.7 -0.5 -0.3
Blood clot in the leg (DVT) 1.9 2.5 4.2 1.6 -1.3 2.0 0.8 0.9 1.7 1.6 2.0 0.9 1.6 1.6 1.6 1.7 1.9 1.7
Medication: Paracetamol 0.1 0.1 0.6 0.3 -0.4 0.0 0.3 -0.0 -0.8 -0.5 0.2 0.3 0.4 0.3 0.3 -0.1 -0.3 -0.4
Headache pain in last month 0.1 0.2 0.6 -0.2 0.2 -0.8 0.3 -0.3 -0.3 -0.7 -0.3 -0.2 -0.1 -0.1 -0.1 -0.5 0.2 -0.6
Medication for cholesterol, blood pressure or diabetes 0.2 0.4 1.0 -0.6 0.6 -0.0 1.0 -0.7 0.1 -0.6 -0.6 -1.0 -0.6 -0.6 -0.6 -0.8 -0.2 -0.6
Glaucoma (self-reported) 0.3 0.4 1.4 -0.7 0.7 -0.6 0.2 -0.0 -1.2 -0.3 -0.4 -0.5 -0.6 -0.6 -0.6 -0.3 -1.0 -0.4
Gout (self-reported) 0.4 0.5 4.0 -0.1 0.1 -0.1 0.7 1.0 2.0 0.8 -0.1 -0.1 -0.1 -0.1 -0.1 0.6 -0.6 0.7
Hypothyroidism/myxoedema (self-reported) 0.3 0.7 1.8 0.8 -0.9 0.9 1.4 -0.9 0.2 -0.0 1.2 -0.1 0.8 0.8 0.8 0.3 1.2 0.4
Medication: Amlodipine 0.2 0.2 0.6 -0.4 0.8 -0.7 0.4 -0.4 -0.7 -0.5 -0.4 -0.1 -0.4 -0.4 -0.4 -0.3 -0.2 -0.6
Medication: Ventolin 100micrograms inhaler 0.3 0.4 1.8 0.5 -0.7 -1.3 -0.2 0.8 0.9 0.3 0.2 0.7 0.5 0.5 0.5 0.4 0.1 0.4
Birth weight 1.5 3.4 5.8 -2.2 2.4 0.1 0.2 -1.9 -1.8 -1.0 -2.1 -1.4 -2.2 -2.3 -2.3 -1.4 -2.4 -1.4
Chronic bronchitis/emphysema (mother) 0.7 0.8 2.5 -1.1 0.8 0.5 -0.4 -0.3 -1.0 -0.4 -1.2 -0.6 -1.2 -1.2 -1.2 -0.7 -1.6 -0.7
High blood pressure (siblings) 0.8 1.1 2.3 0.9 -0.7 0.9 -0.9 0.7 1.4 1.3 0.8 1.5 0.9 0.9 0.9 1.5 0.4 1.2
Forced vital capacity (FVC), Best measure 2.6 9.7 60.8 2.4 -3.9 -0.4 -7.8 2.7 1.2 1.0 -0.8 5.3 2.5 2.5 2.5 1.6 -1.9 0.5
Body fat percentage 4.9 19.3 139.2 -2.9 5.1 -1.0 11.8 -2.5 -3.3 -3.2 1.3 -6.4 -2.9 -2.9 -2.9 -3.0 2.3 -2.2
Leg fat percentage (right) 5.1 18.5 134.6 -2.8 5.3 -0.9 11.6 -2.6 -3.1 -2.6 1.6 -6.4 -2.8 -2.8 -2.8 -2.5 2.4 -1.6
Arm fat-free mass (right) 0.3 1.4 4.0 -0.2 -0.2 -2.0 -1.3 0.3 -1.9 -1.9 -1.0 0.4 -0.2 -0.2 -0.2 -1.4 -1.1 -1.8
Exposure to tobacco smoke outside home 0.6 0.8 3.2 -0.6 1.1 0.4 1.8 -1.0 -0.5 -1.0 0.1 -1.2 -0.6 -0.6 -0.6 -0.9 0.0 -0.8
Comparative body size at age 10 19.7 54.4 392.0 -4.7 8.9 -0.8 19.8 -6.7 -3.7 -4.1 3.0 -10.8 -4.7 -4.7 -4.7 -4.2 5.7 -2.3
Number of full brothers 0.4 0.5 5.6 -0.3 0.1 -0.7 2.4 -0.0 -0.9 0.1 0.3 -0.8 -0.2 -0.2 -0.2 0.2 -0.2 0.2
Worry too long after embarrassment 1.7 2.9 5.3 -2.0 2.2 0.4 2.1 -1.6 -1.1 -1.3 -1.5 -2.3 -2.0 -2.0 -2.0 -1.7 -1.0 -1.2
Seen a psychiatrist for nerves, anxiety, tension or depression 1.4 1.9 3.1 -1.7 1.5 0.2 -0.2 -1.5 -0.2 -0.9 -1.4 -1.6 -1.7 -1.7 -1.7 -1.3 -1.5 -1.1
Wheeze or whistling in the chest in last year 0.2 0.3 1.6 -0.3 0.1 -1.2 0.9 -0.0 -0.4 -0.7 -0.0 -0.4 -0.3 -0.3 -0.3 -0.7 0.5 -0.5
Number of children fathered 1.6 1.8 2.9 1.7 -1.3 -0.5 -0.9 1.1 1.3 0.9 1.2 1.7 1.7 1.7 1.7 1.4 1.0 1.0
Reason for reducing amount of alcohol drunk: Health precaution 2.7 3.2 9.7 1.1 -2.1 1.8 -3.1 0.6 2.2 2.3 0.5 2.4 1.1 1.1 1.1 1.9 0.4 2.0
Age at first live birth 0.8 1.5 4.5 -1.0 0.9 -0.8 -1.1 -0.7 -0.3 -1.6 -2.1 -0.7 -0.9 -0.9 -0.9 -1.5 -1.7 -1.8
Pulse wave peak to peak time 0.4 0.5 2.2 0.7 -0.4 0.3 -0.8 1.5 0.1 0.6 0.2 0.8 0.7 0.7 0.7 0.9 0.0 0.4
Health satisfaction 0.3 0.4 1.1 -0.6 0.9 1.1 0.9 -0.2 -0.5 0.7 -0.3 -0.5 -0.7 -0.6 -0.6 0.4 -0.9 0.5
Shortness of breath walking on level ground 0.3 0.3 0.6 0.6 -0.7 0.3 0.2 0.3 -0.7 0.3 0.8 0.6 0.6 0.6 0.6 0.6 0.5 0.4
Qualifications: College or University degree 0.4 1.1 2.1 -1.4 1.2 -0.3 -1.2 -0.4 -1.0 0.5 -1.4 -0.4 -1.4 -1.4 -1.4 -0.2 -1.2 0.0
Eye problems/disorders: None of the above 2.4 2.8 5.3 2.0 -2.3 -0.9 -1.3 2.0 1.5 1.0 1.1 1.9 2.0 2.0 2.0 1.2 1.6 1.2
Mouth/teeth dental problems: Loose teeth 9.9 11.7 19.7 -3.9 4.4 -0.1 2.2 -3.3 -3.7 -2.9 -2.8 -4.3 -3.9 -3.9 -3.9 -3.4 -3.2 -3.0
Emphysema/chronic bronchitis 1.9 2.1 3.0 1.4 -1.6 1.6 -0.3 1.4 1.7 1.7 1.3 1.6 1.4 1.4 1.4 1.7 1.1 1.7
Medication for pain relief, constipation, heartburn 0.2 0.3 0.9 -0.7 0.7 0.0 0.6 -0.2 0.7 0.0 -0.4 -0.9 -0.6 -0.6 -0.6 -0.4 0.4 0.0
Neck or shoulder pain in last month 0.4 0.6 2.3 0.9 -0.5 -0.5 0.7 0.4 -0.3 -0.0 1.3 0.1 1.0 1.0 1.0 0.4 1.5 0.1
Medication: Blood pressure 0.5 0.8 2.6 1.1 -1.0 -0.5 -1.5 0.5 -0.3 0.3 0.6 1.6 1.1 1.1 1.1 0.7 0.2 0.3
Angina (self-reported) 1.3 1.6 6.2 1.2 -0.6 0.6 1.5 0.7 0.3 0.8 2.5 0.1 1.3 1.3 1.3 1.1 2.2 1.3
Migraine (self-reported) 0.3 0.4 2.8 -0.0 -0.1 -0.2 1.7 -0.6 -0.1 -0.8 0.6 -0.9 -0.0 -0.0 -0.0 -0.7 0.9 -0.4
Medication: Ibuprofen 0.3 0.4 1.0 0.6 -0.8 -0.5 -1.0 -0.3 -1.0 -0.6 0.0 0.9 0.6 0.6 0.6 -0.1 -0.4 -0.5
Medication: Allopurinol 0.3 0.4 1.0 -0.5 0.5 -0.6 0.8 0.5 0.8 0.6 -0.5 -0.6 -0.6 -0.6 -0.6 0.3 -1.0 0.4
Medication: Omeprazole 1.0 1.2 4.4 0.5 -0.6 1.2 -1.2 0.7 -0.0 2.1 0.4 1.6 0.6 0.5 0.5 1.9 -0.3 1.6
Medication: Seretide 50 evohaler 0.2 0.2 2.2 -0.3 0.4 -1.5 0.1 -0.1 0.3 0.2 -0.3 -0.2 -0.3 -0.3 -0.3 0.0 0.4 0.1
Mean time to correctly identify matches 0.6 1.1 6.9 0.7 -1.3 -0.2 -2.6 1.1 -0.1 0.5 -0.5 1.4 0.7 0.7 0.7 0.5 -1.4 0.2
Heart disease (mother) 8.1 9.9 14.7 3.8 -3.6 -0.3 0.8 3.6 2.7 2.1 3.7 3.2 3.8 3.8 3.8 3.2 3.4 2.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 2.3 -0.1 -0.4 1.2 -1.5 0.7 1.1 0.9 -0.3 0.6 -0.1 -0.2 -0.2 0.3 0.6 0.8
Whole body fat mass 3.6 15.0 92.5 -2.7 4.4 -1.3 9.6 -2.3 -3.5 -3.6 0.7 -5.5 -2.7 -2.7 -2.7 -3.3 1.6 -2.6
Leg fat mass (right) 4.3 16.6 106.1 -2.8 4.7 -1.4 10.3 -2.7 -3.5 -3.5 1.0 -6.0 -2.8 -2.8 -2.8 -3.2 1.9 -2.4
Arm predicted mass (right) 0.3 1.4 4.3 -0.3 -0.2 -2.1 -1.3 0.2 -1.9 -2.0 -1.0 0.3 -0.2 -0.2 -0.2 -1.5 -0.9 -1.9
Pulse rate, automated reading 2.1 6.7 13.2 -3.2 2.8 -0.7 -2.4 -1.0 -3.1 -1.0 -3.6 -1.4 -3.3 -3.3 -3.3 -2.1 -3.1 -1.7
Alcohol intake frequency. 0.9 2.2 5.2 -1.2 1.7 -0.5 1.7 -1.0 -0.8 -2.3 -0.7 -2.2 -1.2 -1.2 -1.2 -2.0 -0.5 -2.0
Comparative height size at age 10 2.5 13.6 56.6 3.1 -5.0 0.4 -7.5 3.6 2.1 2.7 0.4 6.6 3.2 3.2 3.2 3.1 0.2 2.1
Number of full sisters 0.2 0.2 0.8 -0.3 0.6 0.3 0.9 -0.9 -0.2 -0.3 -0.3 -0.7 -0.4 -0.4 -0.4 -0.4 -0.1 -0.3
Suffer from ‘nerves’ 0.7 1.2 2.7 -1.4 0.8 -0.0 0.2 -1.4 -0.9 -0.7 -1.6 -0.9 -1.3 -1.4 -1.4 -1.1 -0.6 -0.9
Overall health rating 0.3 0.6 2.6 -0.2 0.3 1.1 1.6 0.6 0.4 0.9 0.7 -0.2 -0.2 -0.2 -0.2 0.6 1.3 1.0
Chest pain or discomfort 0.1 0.1 0.4 0.2 -0.3 0.3 0.7 -0.1 -0.3 0.0 0.2 -0.1 0.2 0.2 0.2 0.3 -0.4 0.1
Had major operations 0.4 0.4 0.9 -0.5 0.3 -0.1 -0.8 -0.2 -0.2 -0.8 -0.7 -0.6 -0.6 -0.6 -0.6 -0.9 -1.0 -0.8
Age at last live birth 0.9 1.3 3.8 -0.1 -0.5 -2.0 -1.6 0.3 0.1 -1.7 -1.8 0.2 -0.1 -0.1 -0.1 -1.3 -1.7 -1.7
Family relationship satisfaction 0.1 0.2 1.1 -0.3 -0.4 1.1 -0.7 -0.1 0.4 0.3 -0.4 0.2 -0.2 -0.2 -0.2 0.1 -0.3 0.1
Leg pain on walking 0.3 0.4 1.0 0.4 -0.1 0.8 0.6 0.8 -0.5 1.0 0.9 0.2 0.3 0.3 0.3 1.0 -0.2 0.9
Qualifications: NVQ or HND or HNC or equivalent 0.1 0.2 0.6 0.3 -0.2 -0.7 0.5 -0.8 0.6 -0.1 0.1 0.1 0.4 0.4 0.4 0.1 0.4 -0.1
Commuting to job workplace: Car/motor vehicle 0.5 0.6 2.2 0.5 -0.3 -1.5 -0.3 -1.0 -0.3 -1.5 0.1 -0.1 0.6 0.6 0.6 -0.7 -0.2 -1.2
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 1.0 -0.7 0.4 0.1 -0.9 -0.5 -0.3 -0.5 -1.0 -0.1 -0.7 -0.7 -0.7 -0.6 -0.1 -0.7
Medication: Aspirin 0.5 0.7 1.3 1.2 -1.1 -1.1 -0.4 0.8 0.0 -0.6 0.9 0.6 1.1 1.1 1.1 -0.1 0.8 -0.2
Supplements: Vitamin C 0.3 0.4 1.0 0.9 -1.0 0.6 -0.5 -0.1 0.3 -0.3 0.4 0.7 0.9 0.9 0.9 0.1 -0.1 -0.0
Knee pain experienced in last month 2.9 4.5 8.0 -1.9 1.7 -2.4 0.5 -1.5 -2.5 -2.8 -2.0 -2.1 -1.9 -1.9 -1.9 -2.6 -2.1 -2.8
Hypertension (Self-reported) 0.7 2.1 8.2 1.3 -0.9 -0.8 -2.2 1.3 0.6 1.5 0.5 2.9 1.2 1.2 1.2 1.7 0.9 1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.0 1.1 2.9 0.6 -0.5 1.2 -0.1 0.8 1.3 1.7 1.1 1.0 0.8 0.8 0.8 1.6 0.8 1.6
Illnesses of father: Heart disease 1.2 1.7 3.8 1.1 -0.6 1.8 1.0 0.3 1.5 1.3 1.9 0.5 1.2 1.2 1.2 1.7 1.4 1.5
Illnesses of siblings: Diabetes 0.9 1.1 3.9 0.3 -0.2 1.8 -0.5 0.5 0.8 2.0 0.9 0.8 0.4 0.4 0.4 1.5 1.0 1.8
Smoking status: Previous 3.5 5.3 14.2 -2.5 2.8 0.1 3.8 -1.9 -2.5 -1.6 -1.3 -3.1 -2.4 -2.5 -2.5 -2.0 -1.6 -1.5
Forced expiratory volume in 1-second (FEV1), predicted 2.3 4.7 25.6 1.7 -2.5 0.9 -5.1 2.3 1.4 1.6 0.3 3.4 1.8 1.8 1.8 1.6 0.3 1.4
Whole body fat-free mass 0.3 1.5 4.6 -0.3 -0.1 -1.7 -1.5 0.1 -1.8 -2.1 -1.1 0.4 -0.2 -0.2 -0.2 -1.6 -0.9 -2.0
Leg fat-free mass (right) 0.4 2.3 8.2 -0.9 0.8 -1.7 1.4 -0.6 -1.9 -2.9 -0.7 -1.3 -0.8 -0.8 -0.8 -2.3 -0.1 -2.4
Arm fat percentage (left) 7.7 30.6 187.7 -4.0 6.7 -1.3 13.7 -3.9 -4.4 -4.5 0.9 -8.3 -4.1 -4.1 -4.1 -4.3 2.1 -3.2
Average weekly red wine intake 0.7 1.0 3.0 1.1 -1.3 -1.7 -0.5 1.5 -0.3 -0.2 0.8 1.2 1.2 1.2 1.2 0.3 0.5 0.2
Handedness (chirality/laterality): Left-handed 0.4 0.5 1.5 -0.8 1.2 -0.8 -0.3 0.0 -0.3 -0.3 -1.1 -0.5 -0.7 -0.7 -0.7 -0.5 -0.9 -0.6
Mood swings 0.8 1.4 2.9 -1.2 1.6 0.0 1.2 -1.7 -0.8 -1.1 -1.2 -1.2 -1.1 -1.1 -1.1 -1.2 -1.2 -1.1
Loneliness, isolation 3.3 4.6 9.2 -1.4 1.8 -2.5 2.0 -2.6 -2.6 -3.0 -1.1 -2.7 -1.4 -1.4 -1.4 -2.6 -1.0 -2.8
Long-standing illness, disability or infirmity 0.6 0.9 2.4 0.1 0.1 1.1 1.5 0.2 1.3 1.3 1.2 -0.3 0.0 0.0 0.0 1.0 1.3 1.4
Ever had bowel cancer screening 1.1 1.3 4.2 0.8 -0.6 0.8 -1.4 1.4 0.6 2.0 0.5 1.4 0.7 0.7 0.7 1.8 0.3 1.6
Diabetes diagnosed by doctor 3.8 6.3 11.1 -3.2 3.3 0.2 2.1 -3.0 -1.2 -1.6 -2.1 -3.2 -3.2 -3.2 -3.2 -2.4 -1.2 -1.7
Ever had stillbirth, spontaneous miscarriage or termination 1.0 1.0 3.4 -0.7 0.1 -1.2 -1.1 -0.5 -1.2 -1.2 -1.4 -0.3 -0.6 -0.6 -0.6 -1.1 -1.8 -1.4
Friendships satisfaction 0.6 0.8 1.8 0.8 -1.3 -0.1 -0.6 1.3 1.0 0.6 0.6 0.9 0.9 0.9 0.9 0.6 1.2 0.7
Qualifications: nursing, teaching 1.5 2.3 3.8 1.5 -0.9 0.7 -0.4 1.9 1.6 1.7 2.0 1.2 1.5 1.5 1.5 1.9 1.8 1.8
Commuting to job workplace: Walk 0.2 0.2 0.9 -0.3 0.0 0.9 -0.2 0.7 0.1 0.8 -0.2 0.1 -0.3 -0.3 -0.3 0.3 0.2 0.6
Eye problems/disorders: Cataract 1.1 1.3 2.6 -1.2 1.3 -0.0 0.8 -0.9 -1.6 -0.8 -1.3 -1.1 -1.3 -1.3 -1.3 -0.9 -1.4 -1.0
Mouth/teeth dental problems: Mouth ulcers 0.3 0.4 2.2 -0.1 -0.1 -1.5 -0.9 0.0 -0.2 -0.7 -0.9 0.5 0.0 0.0 0.0 -0.5 -0.7 -0.8
Medication for cholesterol 0.2 0.4 1.5 0.5 -0.7 -0.1 0.8 -0.2 -0.2 -1.2 0.2 -0.6 0.4 0.4 0.4 -0.8 0.2 -0.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.8 0.9 2.2 -1.2 1.3 1.2 -1.1 -0.8 -0.2 0.4 -1.0 -0.4 -1.1 -1.1 -1.1 -0.2 -1.5 -0.0
Back pain experienced in last month 0.5 0.8 1.8 1.0 -0.8 1.4 -0.8 0.7 0.8 0.4 0.9 0.8 1.0 1.0 1.0 0.6 1.0 0.5
Mineral and other dietary supplements 0.2 0.2 1.1 0.1 0.2 0.6 1.1 -0.2 0.4 0.3 0.4 -0.3 0.0 0.0 0.0 0.1 1.0 0.5
Breast cancer (self-reported) 1.1 1.3 3.5 -1.2 0.4 -1.4 -0.5 -0.1 -0.9 -1.3 -1.9 -0.6 -1.1 -1.1 -1.1 -1.5 -1.3 -1.5
Asthma (self-reported) 0.4 0.8 2.0 -1.0 1.0 -1.4 1.4 -1.0 -0.1 0.1 -0.2 -1.0 -1.0 -1.1 -1.1 -0.4 0.4 0.2
Osteoporosis (self-reported) 0.5 0.6 1.7 0.8 -0.7 -0.1 -0.2 0.0 1.2 -0.0 0.9 0.8 0.9 0.9 0.9 0.4 1.3 0.1
Osteoarthritis (self-reported) 0.6 0.8 8.7 0.3 -0.0 -0.7 3.0 0.3 -0.7 -0.5 0.9 -0.7 0.3 0.3 0.3 -0.1 0.8 -0.1
Medication: Aspirin 1.1 1.4 2.9 1.7 -1.7 -0.8 -0.5 1.2 0.3 -0.2 1.4 1.1 1.6 1.6 1.6 0.5 1.3 0.3
Medication: Gliclazide 0.1 0.1 0.9 0.1 0.0 -0.1 0.4 -0.4 0.9 -0.5 0.0 -0.1 0.0 0.0 0.0 -0.4 0.6 -0.4
Illnesses of father: None of the above (group 1) 1.1 1.4 3.2 -1.5 1.8 0.2 0.9 -0.2 -0.7 -0.5 -1.0 -1.7 -1.6 -1.6 -1.6 -1.1 -0.9 -0.6
Smoking status: Current 0.8 1.3 3.0 1.5 -1.3 -0.5 1.6 0.9 0.3 -0.4 1.6 0.4 1.4 1.4 1.4 0.3 1.7 0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.4 1.2 0.5 -0.5 -0.8 -0.9 0.9 0.3 0.7 0.2 1.1 0.5 0.5 0.5 0.8 -0.2 0.6
Whole body water mass 0.3 1.5 4.6 -0.4 -0.1 -1.7 -1.5 0.1 -1.8 -2.1 -1.2 0.3 -0.3 -0.3 -0.3 -1.6 -0.9 -2.0
Leg predicted mass (right) 0.4 2.1 7.7 -0.8 0.7 -1.7 1.3 -0.5 -1.9 -2.8 -0.7 -1.2 -0.8 -0.8 -0.8 -2.2 -0.1 -2.3
Arm fat mass (left) 5.3 21.6 116.6 -3.5 5.5 -1.6 10.8 -3.4 -4.3 -4.4 0.3 -6.7 -3.5 -3.5 -3.5 -4.1 1.4 -3.3
Number of self-reported non-cancer illnesses 1.3 2.3 6.9 1.1 -1.1 1.8 -0.3 0.5 1.0 2.6 1.5 1.8 1.0 1.0 1.0 2.5 0.9 2.4
Average weekly champagne plus white wine intake 1.0 1.4 4.0 1.3 -1.5 0.0 -0.7 2.0 0.8 1.0 0.7 1.6 1.3 1.3 1.3 1.1 0.7 1.0
Miserableness 2.5 4.3 9.7 -1.4 1.6 -2.1 3.0 -1.9 -2.3 -3.1 -1.2 -2.4 -1.4 -1.4 -1.4 -2.7 -0.6 -2.7
Guilty feelings 4.2 6.4 10.0 -2.4 3.0 -0.8 2.5 -2.2 -2.4 -3.2 -2.2 -3.1 -2.4 -2.4 -2.4 -2.9 -2.0 -3.1
Wears glasses or contact lenses 0.1 0.1 0.4 0.1 -0.6 -0.1 0.0 -0.2 -0.1 0.4 0.2 0.4 0.0 0.0 0.0 0.3 0.2 0.3
Ever taken oral contraceptive pill 1.2 1.3 2.8 -1.2 0.8 -0.3 -0.5 -0.9 -1.3 -1.2 -1.6 -0.7 -1.1 -1.1 -1.1 -1.4 -1.7 -1.3
Hearing aid user 2.0 2.3 15.1 -1.1 1.7 -0.3 3.9 -1.3 -1.5 -0.8 -0.3 -2.0 -1.2 -1.2 -1.2 -0.8 -0.1 -0.7
Mother’s age at death 0.1 0.2 0.7 -0.4 0.3 -0.8 0.8 0.4 0.1 0.1 0.1 -0.7 -0.4 -0.4 -0.4 -0.1 0.2 0.1
Financial situation satisfaction 0.4 0.5 1.1 -0.3 -0.0 -1.1 0.5 -0.9 -0.7 -1.0 -0.7 -0.4 -0.3 -0.3 -0.3 -0.8 -0.7 -0.9
Tinnitus: Yes, now most or all of the time 0.2 0.2 1.9 0.0 0.4 -0.7 1.4 0.1 -0.7 -0.1 0.1 -0.4 0.0 0.0 0.0 0.1 -0.1 -0.1
Commuting to job workplace: Public transport 0.8 0.9 1.8 -1.3 0.8 -0.4 1.3 1.1 -0.4 0.4 -0.8 -1.0 -1.3 -1.3 -1.3 -0.3 -1.0 0.2
Eye problems/disorders: Glaucoma 0.1 0.1 0.4 0.2 -0.2 0.6 0.1 0.1 -0.0 0.2 0.5 0.3 0.3 0.3 0.3 0.3 0.1 0.3
Medication: Blood pressure 0.4 0.7 3.7 0.1 -0.2 -0.7 -1.9 0.2 -0.0 1.3 -0.3 1.7 0.1 0.1 0.1 1.0 0.1 0.9
Pain type(s) experienced in last month: Hip pain 1.1 1.4 3.0 1.4 -1.6 -0.6 0.3 0.8 0.7 0.4 1.5 1.1 1.4 1.4 1.4 1.0 1.7 0.6
Supplements: Fish oil (including cod liver oil) 0.3 0.4 1.0 0.4 -0.7 -0.6 -1.0 0.8 0.1 0.8 0.1 0.8 0.5 0.5 0.5 0.9 -0.5 0.6
High cholesterol (Self-reported) 0.3 0.6 2.6 -0.1 0.3 1.1 0.4 0.5 -0.1 1.6 0.8 0.3 0.0 0.0 0.0 1.3 0.4 1.5
Medication: Bendroflumethiazide 0.5 0.7 1.8 -1.1 1.1 -1.2 -0.0 -0.8 -1.4 -0.4 -0.7 -0.3 -1.0 -1.0 -1.0 -0.5 -0.6 -0.5
Medication: Paracetamol 0.4 0.6 1.1 0.9 -0.9 0.3 0.8 0.8 -0.4 0.2 1.1 0.8 1.0 1.0 1.0 0.8 0.2 0.4
Medication: Lisinopril 0.2 0.2 1.7 0.0 -0.1 0.2 -1.3 -0.8 -0.1 0.4 -0.3 0.7 -0.1 -0.1 -0.1 0.3 -0.2 0.1
Medication: Atorvastatin 0.4 0.4 1.4 0.1 0.4 1.2 -0.9 0.6 -1.1 0.9 0.3 0.2 0.1 0.1 0.1 0.8 -0.7 0.8
Illnesses of father: High blood pressure 2.2 2.7 8.1 1.8 -2.5 0.1 -2.2 0.7 1.2 0.9 0.9 2.9 1.8 1.8 1.8 1.4 1.1 1.0
Alcohol drinker status: Never 0.5 0.6 2.2 -0.7 0.7 -0.2 0.6 -0.1 -0.0 -1.2 -0.5 -1.5 -0.7 -0.7 -0.7 -1.3 -0.3 -1.1
Ever smoked 1.7 2.9 9.7 -1.4 1.3 -0.3 3.1 -2.0 -1.8 -2.0 -0.7 -2.2 -1.4 -1.4 -1.4 -1.9 -1.0 -1.7
Basal metabolic rate 0.3 1.7 6.2 -0.7 0.6 -1.8 0.4 -0.3 -2.1 -2.5 -0.8 -0.6 -0.6 -0.6 -0.6 -1.9 -0.3 -2.1
Leg fat percentage (left) 5.2 18.7 139.2 -2.6 5.1 -1.1 11.8 -2.8 -3.0 -2.9 1.7 -6.4 -2.7 -2.7 -2.7 -2.7 2.5 -1.8
Arm fat-free mass (left) 0.5 2.4 6.9 -0.9 0.5 -2.1 -0.9 -0.4 -2.3 -2.6 -1.5 -0.4 -0.9 -0.9 -0.9 -2.2 -1.2 -2.5
Number of operations (self-reported) 0.3 0.4 0.9 0.9 -0.8 -0.1 0.5 0.8 -0.0 -0.4 0.8 0.6 0.9 0.9 0.9 0.3 0.1 -0.1
Average weekly beer plus cider intake 0.2 0.2 0.5 -0.5 0.6 0.7 0.5 -0.7 -0.1 0.7 -0.1 -0.2 -0.5 -0.5 -0.5 0.3 -0.4 0.5
Irritability 0.8 1.3 4.6 -1.4 1.1 1.3 2.1 -1.0 -0.8 0.1 -0.5 -1.3 -1.4 -1.4 -1.4 -0.5 -0.3 0.1
Risk taking 0.3 0.4 1.6 -0.5 0.9 0.1 -0.1 -0.7 -0.4 -0.6 -0.7 -0.6 -0.5 -0.5 -0.5 -0.6 -1.3 -0.7
Ever had prostate specific antigen (PSA) test 0.6 0.7 1.7 1.0 -1.3 -0.5 -1.0 0.8 1.0 0.5 0.3 0.9 1.0 1.0 1.0 0.7 0.1 0.5
Fractured/broken bones in last 5 years 0.6 0.7 2.3 0.7 -1.0 -0.3 0.9 0.6 1.4 0.6 1.0 0.5 0.6 0.6 0.6 0.7 1.5 0.8
Age started oral contraceptive pill 0.4 0.6 1.1 -0.9 1.0 -0.7 0.8 -0.4 -0.4 0.6 -0.5 -0.9 -1.0 -0.9 -0.9 0.2 -1.0 0.3
Diastolic blood pressure, automated reading 0.4 1.2 9.1 0.3 -0.6 0.0 -3.0 0.2 -0.2 1.1 -0.5 2.2 0.3 0.3 0.3 0.9 -0.4 0.7
Ever depressed for a whole week 1.3 1.6 2.7 -0.9 1.5 -1.6 1.4 -0.6 -0.5 -1.6 -1.1 -1.5 -0.9 -1.0 -1.0 -1.4 -1.4 -1.6
Unable to work because of sickness or disability 0.3 0.4 1.4 -0.3 0.3 1.1 1.2 -0.3 0.6 0.6 0.8 -0.4 -0.2 -0.2 -0.2 0.4 0.8 0.6
Commuting to job workplace: Cycle 0.6 0.7 3.0 -1.0 1.7 0.3 1.0 -0.1 -1.1 0.1 -0.6 -1.0 -1.0 -1.1 -1.0 -0.2 -0.3 -0.1
Myopia 0.9 1.3 7.4 0.7 -1.5 -1.6 -2.7 0.8 0.8 0.6 -0.5 1.6 0.7 0.7 0.7 0.5 0.5 0.3
Vascular/heart problems diagnosed by doctor 0.4 1.2 4.5 -1.2 0.8 0.9 1.2 -0.9 -0.1 -1.0 -0.8 -2.1 -1.1 -1.1 -1.1 -1.3 -1.0 -1.0
Cholesterol lowering medication 0.5 0.8 3.7 -0.2 0.4 1.2 -0.5 0.1 0.7 1.9 0.5 0.7 -0.1 -0.1 -0.1 1.4 0.5 1.6
Medication: Omeprazole (e.g. Zanprol) 1.2 1.5 5.9 0.3 -0.5 1.9 -1.0 0.3 -0.1 2.4 0.3 1.6 0.3 0.3 0.3 2.1 -0.4 1.9
Pain experienced in last month 1.5 2.5 8.2 0.8 -0.6 2.4 -0.1 1.0 1.7 2.9 1.1 1.4 0.8 0.8 0.8 2.4 0.7 2.6
Supplements: Calcium 0.9 1.0 5.2 -0.9 0.7 2.3 -1.6 -0.5 1.0 0.7 -0.8 -0.1 -1.0 -1.0 -1.0 0.1 -1.0 0.4
Basal cell carcinoma (self-reported) 1.1 1.3 2.2 1.1 -1.1 0.6 -0.7 1.4 1.4 1.2 0.9 1.4 1.2 1.2 1.2 1.5 0.7 1.1
Heart attack/myocardial infarction (self-reported) 1.4 1.8 4.2 2.0 -1.6 -0.2 -0.1 0.9 0.9 0.2 1.9 1.1 2.0 2.0 2.0 1.1 0.8 0.6
Deep venous thrombosis (DVT) (self-reported) 1.7 2.2 3.4 1.5 -1.3 1.8 0.8 0.8 1.5 1.5 1.9 0.9 1.5 1.5 1.5 1.6 1.8 1.6
Heart disease (siblings) 0.7 0.9 8.6 -0.3 0.6 -0.8 2.9 -0.3 -0.3 -0.1 0.7 -1.4 -0.4 -0.4 -0.4 -0.1 0.8 0.2
Alcohol drinker status: Previous 0.9 1.1 1.9 -0.8 1.3 -0.6 0.8 -1.1 -1.2 -1.4 -0.8 -1.1 -0.8 -0.8 -0.8 -1.1 -1.1 -1.3
Pack years of smoking 1.2 1.7 5.5 -1.2 1.6 2.0 2.3 -1.4 -0.5 -1.0 -0.2 -1.9 -1.2 -1.2 -1.2 -1.1 -0.2 -0.9
Impedance of whole body 1.9 9.8 20.0 2.7 -3.5 2.4 -4.5 3.4 3.5 3.6 1.1 4.4 2.7 2.7 2.7 3.6 0.5 3.1
Leg fat mass (left) 4.3 16.6 108.2 -2.7 4.6 -1.5 10.4 -2.7 -3.4 -3.6 1.0 -6.0 -2.7 -2.7 -2.7 -3.2 1.9 -2.5
Arm predicted mass (left) 0.4 1.8 5.9 -0.6 0.1 -1.7 -0.9 -0.4 -2.1 -2.4 -1.3 -0.1 -0.6 -0.6 -0.6 -1.9 -1.0 -2.2