Best TWAS P=7.45e-17 · Best GWAS P=3.18e-93 conditioned to 5.6e-93
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | DIRC3 | 0.03 | 0.01 | blup | 275 | 0.01 | 1.4e-03 | -7.3 | -5.4 | 6.0e-08 | 0.15 | 0.33 | 0.5 | TRUE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | DIRC3 | 0.09 | 0.10 | lasso | 2 | 0.09 | 2.5e-10 | -8.0 | -8.3 | 7.5e-17 | 0.03 | 1.00 | 0.0 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | DIRC3 | 0.08 | 0.06 | lasso | 5 | 0.07 | 2.7e-07 | -5.5 | 8.3 | 1.2e-16 | -0.01 | 0.00 | 1.0 | TRUE |