Best TWAS P=3.78e-10 · Best GWAS P=5.79e-19 conditioned to NaN
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | KIF9-AS1 | 0.08 | 0.01 | enet | 20 | 0.04 | 1.6e-05 | 3.6 | -5.2 | 2.1e-07 | -0.38 | 0.38 | 0.11 | TRUE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | PRSS45 | 0.03 | 0.00 | blup | 35 | 0.00 | 2.4e-01 | 4.3 | 6.3 | 3.8e-10 | 0.54 | 0.01 | 0.84 | TRUE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | ALS2CL | 0.08 | 0.00 | blup | 74 | 0.03 | 9.3e-03 | 6.0 | 5.4 | 8.4e-08 | 0.41 | 0.01 | 0.89 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | PRSS45 | 0.08 | 0.00 | blup | 35 | 0.02 | 3.5e-02 | 5.6 | 6.0 | 2.4e-09 | 0.49 | 0.01 | 0.66 | FALSE |
| 5 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | PRSS45 | 0.27 | 0.00 | enet | 5 | 0.03 | 2.0e-02 | 6.1 | 5.8 | 9.0e-09 | 0.55 | 0.00 | 0.68 | TRUE |