TWAS hub - ALS2CL

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2580	0.0470	1.7e-13	0.082	0.134	0.134	NA	0.147	3.5e-10	5.3e-16	5.5e-16	NA	1.8e-17
2	GTEx	Adipose Subcutaneous	0.0660	0.0290	2.4e-03	0.015	NA	0.004	NA	0.009	1.8e-02	NA	1.4e-01	NA	6.1e-02
3	GTEx	Adrenal Gland	0.3213	0.0786	2.2e-04	0.256	NA	0.199	NA	0.207	1.1e-09	NA	1.1e-07	NA	5.7e-08
4	GTEx	Artery Aorta	0.2010	0.0580	1.7e-04	0.073	NA	0.126	NA	0.106	7.7e-05	NA	2.0e-07	NA	1.9e-06
5	GTEx	Artery Tibial	0.2284	0.0585	3.9e-05	0.112	NA	0.097	NA	0.109	4.4e-09	NA	5.0e-08	NA	7.3e-09
6	GTEx	Brain Cortex	0.2670	0.1020	4.2e-03	0.247	NA	0.148	NA	0.208	1.8e-07	NA	7.1e-05	NA	2.0e-06
7	GTEx	Cells Transformed fibroblasts	0.1790	0.0530	6.0e-05	0.021	NA	0.066	NA	0.075	1.0e-02	NA	1.1e-05	NA	3.0e-06
8	GTEx	Esophagus Mucosa	0.2080	0.0530	5.0e-07	0.097	NA	0.106	NA	0.113	4.8e-07	NA	1.5e-07	NA	5.7e-08
9	GTEx	Heart Left Ventricle	0.2574	0.0723	1.0e-04	0.097	NA	0.030	NA	0.057	7.4e-06	NA	1.0e-02	NA	5.7e-04
10	GTEx	Muscle Skeletal	0.1781	0.0537	1.8e-05	0.072	NA	0.101	NA	0.098	1.5e-07	NA	3.8e-10	NA	8.2e-10
11	GTEx	Skin Not Sun Exposed Suprapubic	0.2570	0.0680	1.6e-06	0.123	NA	0.166	NA	0.165	3.0e-07	NA	2.1e-09	NA	2.4e-09
12	GTEx	Skin Sun Exposed Lower leg	0.1760	0.0480	2.3e-06	0.082	NA	0.131	NA	0.132	2.4e-07	NA	5.3e-11	NA	5.0e-11
13	GTEx	Thyroid	0.1710	0.0450	4.8e-07	0.117	NA	0.127	NA	0.128	3.2e-09	NA	6.2e-10	NA	5.2e-10
14	METSIM	Adipose	0.0334	0.0147	6.9e-04	0.019	0.019	0.019	0.020	0.024	6.0e-04	5.8e-04	6.6e-04	4.8e-04	1.5e-04
15	ROSMAP	Brain Pre-frontal Cortex	0.3495	0.0502	0.0e+00	0.247	0.280	0.306	0.305	0.309	1.8e-31	3.9e-36	6.6e-40	7.0e-40	2.1e-40
16	TCGA	Colon Adenocarcinoma	0.0830	0.0420	2.7e-03	-0.001	0.028	0.007	NA	0.008	3.6e-01	9.3e-03	1.2e-01	NA	1.0e-01
17	TCGA	Lung Adenocarcinoma	0.0437	0.0293	3.5e-03	0.009	0.022	0.016	NA	0.007	2.9e-02	1.2e-03	5.4e-03	NA	4.1e-02
18	TCGA	Ovarian Serous Cystadenocarcinoma	0.0850	0.0380	2.9e-04	0.007	0.051	0.023	NA	0.007	9.5e-02	2.2e-04	1.0e-02	NA	1.0e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Average weekly spirits intake	4.9	6.1	12.7	-2.4	-2.7	-2.5	-0.9	-1.7	-2.2	-0.9	-3.1	-2.5	-3.0	-2.6	-2.8	-2.2	-3.0	-2.6	2.6	1.0	-3.6
Blood White Count	4.6	34.3	163.8	6.0	7.7	4.4	2.8	2.8	5.9	-5.8	5.3	4.8	4.3	6.5	6.4	5.5	12.8	5.7	-4.2	-2.8	3.2
Alzheimer’s Disease (in father)	4.3	4.6	8.2	-2.4	-2.9	-1.4	-1.5	-2.8	-2.4	0.2	-2.1	-1.5	-2.0	-2.1	-2.6	-2.5	-0.7	-2.4	2.6	2.1	-2.4
Type 2 Diabetes (T2D) (2012)	4.3	5.0	13.6	2.3	2.6	2.8	1.5	1.9	1.4	-2.1	2.4	3.1	3.3	2.4	2.3	1.1	3.7	2.1	-0.3	0.5	0.8
Blood clot in the leg (DVT)	4.2	5.4	15.1	2.7	1.8	3.2	1.7	2.3	1.2	-1.7	3.2	3.1	2.3	2.1	2.8	1.2	1.4	2.2	-1.9	-0.0	3.9
Number of children fathered	4.1	4.6	8.7	-2.8	-1.9	-2.5	-2.3	-2.8	-2.5	0.4	-2.8	-2.7	-1.6	-2.5	-3.0	-1.9	0.5	-2.8	0.8	0.3	-0.3
Eye problems/disorders: Cataract	4.1	4.7	7.8	2.4	2.7	2.0	2.5	2.1	2.2	1.4	2.5	1.9	2.5	2.8	2.6	2.1	0.2	2.6	-2.0	-0.8	1.8
Breast Cancer	3.7	8.9	28.7	-2.4	-3.8	-2.1	-2.3	-0.3	-2.4	-1.1	-2.4	-1.6	-3.8	-2.9	-2.9	-3.0	-3.0	-2.8	5.4	2.0	-5.1
Risk taking	3.7	5.4	18.8	2.4	3.3	-0.1	0.7	1.7	3.5	-0.1	0.9	0.2	-0.2	2.6	2.2	3.6	1.9	2.5	-3.1	-4.3	1.3
Deep venous thrombosis (DVT) (self-reported)	3.6	4.6	12.7	2.4	1.6	2.9	1.4	2.2	1.1	-2.1	2.9	2.9	2.2	2.0	2.5	1.1	1.4	1.9	-1.6	-0.1	3.6
Medication: Lansoprazole	3.5	4.0	11.0	2.1	2.4	1.9	1.6	1.6	2.2	-1.0	1.9	1.9	1.6	2.2	2.3	1.9	3.3	2.5	-1.6	-1.6	1.0
Type 2 Diabetes (T2D) (2018)	3.0	5.6	17.4	1.8	2.0	3.2	1.8	2.1	1.3	0.3	3.1	3.3	3.4	2.7	2.6	0.9	4.2	2.5	-1.1	0.8	1.6
Pain all over the body in last month	3.0	3.2	8.3	1.8	1.7	1.6	2.1	2.9	1.9	0.8	2.0	1.7	1.9	2.2	2.1	1.7	-0.8	2.1	-1.5	-0.5	1.0
Illnesses of father: Heart disease	3.0	4.1	8.4	2.4	2.2	2.6	2.9	1.6	1.4	-0.4	2.9	2.7	2.5	2.3	2.7	1.2	0.5	2.0	-0.3	1.6	0.7
Bilateral oophorectomy (both ovaries removed)	2.9	3.4	8.2	1.3	0.6	2.9	1.5	2.4	0.7	1.4	2.9	2.7	2.8	1.2	2.1	0.1	0.5	1.6	-0.5	2.1	1.9
Waist Hip Ratio (WHR)	2.8	12.7	53.0	3.8	3.7	3.8	2.5	3.0	3.2	-1.9	3.7	3.8	3.5	3.5	4.1	2.3	7.3	4.2	-1.9	-1.1	2.5
Forced expiratory volume in 1-second (FEV1), predicted	2.8	5.8	13.2	-2.4	-2.4	-3.1	-2.4	-1.6	-2.0	0.0	-3.5	-3.3	-2.6	-3.6	-3.2	-2.1	0.2	-2.5	1.3	-0.4	-2.3
Major Depression (MDD)	2.7	3.2	8.6	2.4	2.8	0.5	0.9	2.0	2.9	0.2	1.1	1.0	1.3	2.2	1.8	2.9	0.6	2.2	-1.2	-2.1	0.3
Diabetes (father)	2.6	3.2	5.3	1.7	2.1	1.4	0.8	1.8	2.1	0.9	1.7	1.3	2.1	2.1	1.9	2.2	2.3	2.0	-2.1	-1.2	1.8
Illness, injury, bereavement, stress in last 2 years	2.5	3.1	6.7	-2.1	-2.6	-0.7	-0.7	-1.1	-2.5	1.7	-1.3	-1.0	-0.9	-2.6	-2.1	-2.6	-1.1	-2.1	1.0	2.2	-0.5
Age at First Birth	2.4	3.5	8.8	-2.2	-2.4	-0.5	-2.0	-0.8	-2.8	-0.9	-1.2	-0.7	-0.9	-2.3	-2.1	-3.0	0.8	-2.1	2.1	2.6	-1.1
Osteoarthritis (self-reported)	2.4	3.0	10.4	1.3	2.7	-0.4	0.4	1.2	2.7	-1.0	0.4	-0.1	0.6	2.0	1.5	2.6	0.7	1.8	-2.6	-3.2	1.1
Ever had prostate specific antigen (PSA) test	2.4	2.8	6.7	-1.3	-2.6	-0.8	-1.6	-2.0	-2.1	0.3	-1.7	-1.0	-0.5	-2.3	-2.2	-2.1	-0.5	-1.9	1.9	1.7	-0.9
Eye problems/disorders: None of the above	2.3	2.7	5.9	-1.7	-2.4	-1.6	-1.7	-1.4	-1.9	-0.4	-1.7	-1.6	-2.1	-2.2	-2.0	-1.5	-1.0	-2.1	0.9	0.5	-0.5
Age at last live birth	2.3	3.4	7.3	-2.0	-2.5	-0.6	-0.2	-1.8	-2.4	0.9	-1.4	-0.7	-1.5	-2.2	-2.0	-2.7	-0.6	-2.1	2.4	2.6	-1.4
Mean Putamen Volume	2.1	2.4	6.8	-1.7	-1.0	-2.6	-2.0	-1.3	-0.6	-0.7	-2.0	-2.4	-2.2	-1.8	-1.7	-0.2	-0.1	-1.8	0.2	-1.3	-1.0
Sensitivity / hurt feelings	2.1	3.6	8.3	2.5	2.9	1.4	1.4	1.4	2.6	-1.4	2.1	1.5	1.5	2.7	2.5	2.2	0.3	2.3	-1.4	-1.2	0.9
Medication: Levothyroxine sodium	2.1	3.6	13.8	2.2	2.1	1.7	1.3	3.7	2.2	0.9	1.9	1.9	1.6	1.5	2.2	2.1	-1.0	2.4	-1.0	-1.2	0.9
Medication: Seretide 50 evohaler	2.1	2.5	6.2	-1.5	-0.7	-2.5	-1.2	-1.6	-0.1	0.8	-2.0	-2.4	-2.4	-1.2	-1.4	0.1	-2.5	-1.4	0.8	-0.6	-1.7
Loneliness, isolation	2.1	2.9	6.3	1.9	2.5	1.2	1.0	2.0	2.4	-1.1	1.6	1.5	1.6	2.3	2.2	2.3	0.3	2.1	-0.4	-1.1	0.1
Medication for cholesterol	2.1	3.2	6.3	-2.1	-2.1	-2.0	-1.9	-1.8	-2.2	-0.2	-2.3	-2.1	-1.3	-2.4	-2.5	-1.5	-0.7	-2.5	0.5	0.5	-0.2
Medication for hormone replacement therapy	2.0	2.2	6.8	1.6	1.7	-0.2	1.2	1.7	2.6	0.7	0.5	0.1	-0.5	1.6	1.5	2.1	0.2	2.0	-1.2	-2.6	-0.6
Time employed in main current job	2.0	2.4	4.6	-1.6	-2.0	-0.3	-1.1	-1.0	-1.9	-0.9	-1.0	-0.5	-1.8	-1.8	-1.4	-2.1	-0.8	-1.5	2.2	2.0	-1.8
Medication: Allopurinol	1.9	2.5	7.1	-1.9	-1.2	-1.6	-1.6	-1.7	-1.5	0.8	-2.0	-1.2	-0.8	-1.4	-2.1	-1.0	0.1	-1.9	2.7	0.4	-2.3
Pain experienced in last month	1.9	3.2	9.4	-1.3	-2.3	0.1	-1.1	-1.3	-2.2	-2.0	-0.8	-0.1	-0.9	-1.9	-1.5	-2.5	-1.5	-1.5	2.8	3.1	-1.7
Lupus	1.8	2.7	7.2	-1.3	-1.4	-2.7	-1.2	-1.3	-0.4	-0.1	-2.6	-2.6	-2.7	-1.9	-2.0	-0.5	0.3	-1.4	0.3	-1.6	-1.2
Multivitamins +/- minerals	1.8	2.3	11.0	-0.8	-0.9	-2.1	0.2	-1.6	-0.3	2.2	-1.7	-2.4	-1.8	-1.2	-1.3	0.2	-3.3	-0.9	-0.4	-1.1	-0.5
Heart attack	1.8	2.3	7.7	1.3	2.8	0.8	0.4	0.8	1.8	-0.7	1.5	0.9	1.0	2.7	2.1	1.8	1.6	1.5	-1.2	-1.3	0.4
Impedance of arm (left)	1.8	8.3	32.6	-1.4	-4.7	1.8	0.3	-0.1	-4.8	-0.5	0.3	1.3	0.1	-3.2	-2.0	-5.6	0.3	-2.3	3.6	5.7	0.1
Knee pain experienced in last month	1.8	2.7	10.3	1.1	2.6	-0.5	0.3	0.9	2.0	0.1	0.3	-0.1	0.4	1.8	1.2	2.5	2.3	1.2	-2.5	-3.2	1.5
Alcohol drinker status: Previous	1.8	2.0	6.4	1.7	1.0	2.0	2.5	1.3	1.3	-1.1	1.4	2.1	1.5	1.1	1.6	0.6	-0.6	1.8	0.5	0.6	-0.2
Body Mass Index (BMI) (2010)	1.7	2.3	9.1	0.6	2.3	-0.8	0.4	0.0	2.6	-1.0	-0.1	-0.6	-0.4	1.4	1.1	2.6	-0.6	1.4	-2.1	-3.0	0.3
Eye problems/disorders: Diabetes related eye disease	1.7	1.8	5.8	0.8	1.0	2.1	0.5	1.3	0.2	-0.8	1.5	2.3	2.2	1.1	1.1	-0.3	2.4	1.1	0.8	1.3	-0.1
Hand grip strength (right)	1.7	4.6	10.2	-1.5	-1.8	-2.8	-2.2	-2.0	-1.2	-1.1	-3.2	-2.5	-2.7	-2.6	-2.5	-1.0	-1.8	-2.1	1.9	-0.5	-3.1
Qualifications: CSEs or equivalent	1.7	2.2	6.8	0.7	2.5	-1.0	0.2	-0.0	2.0	1.2	0.2	-0.9	-0.1	1.7	1.2	2.6	2.0	0.9	-1.8	-2.5	0.5
Serious illness, injury or assault to yourself	1.7	2.1	4.1	1.8	1.6	0.9	1.2	2.0	1.6	-1.0	1.2	1.3	1.1	2.0	1.6	1.7	-0.7	1.6	-0.9	-1.9	0.7
Hypothyroidism/myxoedema (self-reported)	1.7	3.4	12.3	2.2	1.8	2.2	1.0	3.5	1.9	0.3	2.2	2.4	1.8	1.5	2.2	1.4	-0.8	2.3	-0.3	-0.8	0.8
Age at first live birth	1.7	3.0	9.0	-1.3	-2.5	-0.0	0.5	-0.5	-2.5	1.1	-1.1	-0.2	-0.7	-2.4	-1.9	-3.0	0.0	-1.7	2.3	3.0	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.7	2.0	5.5	1.3	2.3	1.0	1.4	0.8	1.8	0.7	1.6	1.3	1.4	2.3	1.9	1.8	-0.1	1.6	-0.5	-0.6	-0.2
Number of full sisters	1.7	2.1	9.0	-0.2	1.2	-1.8	-0.8	-1.0	1.1	1.4	-0.9	-2.1	-0.8	0.8	0.1	1.7	-0.3	0.2	-2.8	-3.0	1.0
Mouth/teeth dental problems: Mouth ulcers	1.7	2.8	15.7	-0.9	1.1	-1.7	-4.0	-2.1	0.7	2.4	-0.3	-1.7	-0.6	1.4	-0.0	1.7	-1.3	-0.4	-1.7	-2.2	1.1
Depression (self-reported)	1.6	1.9	6.9	-1.0	-0.5	-2.0	-1.6	-1.1	0.0	0.0	-1.6	-2.0	-2.6	-1.0	-0.9	0.6	-2.2	-0.8	-0.6	-1.6	-0.6
Worry too long after embarrassment	1.6	2.7	5.3	1.8	2.3	1.2	1.0	1.2	2.1	0.5	1.6	1.2	2.0	2.1	1.9	1.9	2.2	2.0	-1.1	-1.0	0.7
Tinnitus: Yes, now most or all of the time	1.6	1.8	5.7	1.3	1.4	1.4	1.1	0.6	0.4	-1.1	1.6	1.3	2.4	1.9	1.3	1.0	1.9	0.9	-1.0	0.3	1.6
Medication: Lisinopril	1.6	2.1	5.3	1.4	1.4	2.2	0.7	1.4	0.3	-2.1	2.1	2.3	1.9	1.3	1.6	0.1	0.7	1.1	0.3	1.7	0.1
Height	1.5	28.6	60.5	-5.7	-7.3	-5.7	-5.6	-2.1	-5.1	4.3	-6.5	-5.7	-5.5	-7.8	-6.9	-5.0	-0.9	-6.0	4.3	1.9	-4.4
Ever had hysterectomy (womb removed)	1.5	1.7	5.2	1.3	0.8	1.3	1.3	1.4	1.0	2.1	1.4	1.1	1.0	0.8	1.3	0.6	-0.4	1.4	-1.7	-0.4	2.3
Exposure to tobacco smoke outside home	1.5	2.0	10.9	0.3	1.8	-2.0	-0.9	-0.3	1.8	0.7	-1.0	-1.6	-1.1	0.8	0.2	2.3	0.2	0.3	-1.2	-3.3	-0.4
Medication: Bendroflumethiazide	1.5	2.3	5.8	1.2	1.2	2.2	1.6	2.2	0.7	-1.7	2.0	2.4	1.1	1.3	1.8	-0.2	-1.2	1.5	0.8	1.7	-0.6
Fractured/broken bones in last 5 years	1.5	2.0	5.8	1.4	1.6	-0.4	1.2	1.2	2.4	1.7	-0.2	-0.3	-0.6	1.2	0.9	2.0	-0.7	1.9	-1.5	-2.4	-0.8
Heart attack/myocardial infarction (self-reported)	1.5	2.0	6.9	1.2	2.6	0.7	0.4	0.6	1.7	-0.9	1.3	0.9	0.8	2.6	1.9	1.7	1.3	1.4	-0.8	-1.2	-0.0
Coronary Artery Disease (CAD)	1.4	1.7	4.8	1.6	1.4	1.1	1.5	0.8	1.2	-2.2	1.4	1.4	1.2	1.8	1.8	1.1	1.0	1.4	-0.1	-0.4	-0.1
Vitamin and mineral supplements	1.4	1.9	13.6	0.5	1.1	1.8	-0.4	0.9	0.2	-0.9	1.4	2.0	1.9	1.3	1.1	-0.1	3.7	0.7	0.4	0.6	0.4
Impedance of arm (right)	1.4	6.3	27.0	-0.9	-4.2	1.8	0.7	0.3	-4.1	-0.4	0.5	1.3	0.3	-2.7	-1.5	-4.8	0.2	-1.8	3.1	5.2	0.1
Myopia	1.4	2.1	6.0	-0.6	-2.3	1.1	-0.1	1.1	-2.0	0.9	0.7	1.1	1.0	-0.7	-0.7	-2.1	-2.4	-1.0	2.1	2.1	0.6
Cardiovascular Disease	1.3	4.3	9.0	2.2	3.0	2.3	0.4	2.1	2.2	-1.4	2.9	2.6	1.8	2.6	2.9	1.7	2.0	2.3	-0.5	0.5	0.2
Diabetes (self-reported)	1.3	1.9	8.4	1.0	0.9	2.0	0.9	1.2	0.9	0.7	1.5	2.1	1.9	1.3	1.3	0.3	2.9	1.5	0.1	1.1	0.0
Medication: Ramipril	1.3	1.6	4.8	0.6	1.5	1.1	1.1	1.2	1.0	0.3	1.9	1.2	1.1	2.2	1.8	1.4	0.1	1.0	-1.4	-0.6	1.5
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	2.8	1.6	1.5	0.8	0.9	1.5	1.4	-0.2	1.3	0.8	0.8	1.1	1.5	1.5	0.7	1.7	-1.4	-1.0	1.3
Diabetes diagnosed by doctor	1.3	2.1	11.6	0.9	1.2	1.9	0.9	0.9	1.0	-0.1	1.6	2.0	1.9	1.6	1.4	0.5	3.4	1.5	-0.0	0.7	-0.1
Mineral and other dietary supplements	1.3	1.8	5.2	0.3	0.3	2.0	-0.2	-0.1	-0.8	-2.3	1.3	2.1	1.5	0.7	0.7	-1.1	2.2	0.1	1.5	2.1	0.1
Medication: Aspirin	1.3	1.7	5.1	0.3	1.4	1.8	-1.2	-0.5	0.0	-2.0	1.9	1.7	1.0	2.3	1.6	0.5	1.1	0.3	-0.2	1.0	1.1
Illnesses of father: None of the above (group 1)	1.3	1.6	5.4	-0.9	-0.9	-2.2	-0.5	-0.9	-0.0	1.4	-1.9	-2.3	-1.8	-1.1	-1.4	0.2	0.0	-0.7	-0.6	-1.5	-0.6
Financial situation satisfaction	1.3	1.6	4.3	-1.1	-0.1	-1.4	-1.0	-1.8	-0.4	-1.9	-1.3	-1.2	-1.1	-0.3	-0.8	-0.0	2.0	-1.2	1.6	0.3	-2.1
HDL Cholesterol	1.2	2.0	7.3	-1.9	-1.8	-0.9	-1.3	-0.8	-1.4	0.2	-1.0	-0.9	-1.7	-1.9	-1.4	-1.6	-2.7	-1.4	0.8	0.3	-0.4
Respiratory disease	1.2	2.7	6.5	1.4	2.1	-0.3	0.9	1.6	2.5	1.9	0.6	-0.1	1.1	1.7	1.3	2.5	-0.1	1.7	-2.3	-2.5	1.2
Hand grip strength (left)	1.2	3.2	7.7	-0.7	-0.7	-2.7	-1.6	-1.6	0.2	-1.5	-2.8	-2.4	-2.5	-1.4	-1.7	0.5	-2.6	-1.1	0.9	-1.8	-2.4
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.9	15.4	1.6	1.7	1.2	1.2	0.5	1.7	-0.7	1.7	1.1	1.4	2.5	2.1	1.9	3.9	1.7	-0.8	-0.3	0.2
Financial difficulties in last 2 years	1.2	1.6	7.0	1.1	1.8	-0.8	0.5	0.3	2.2	-0.4	-0.3	-0.3	0.1	1.8	0.7	2.1	0.5	1.2	-0.4	-2.6	-0.6
Shortness of breath walking on level ground	1.2	1.4	5.5	0.9	1.8	-0.3	0.0	1.3	1.7	-1.5	0.2	0.0	0.2	1.6	1.0	2.0	-0.2	1.0	-0.4	-2.3	-0.2
Family relationship satisfaction	1.2	1.5	6.3	-1.1	0.3	-2.3	-0.6	-1.1	0.1	0.2	-1.8	-2.0	-1.2	-0.6	-1.1	0.4	0.2	-1.0	0.9	-1.0	-2.5
Leg pain on walking	1.2	1.6	5.6	0.2	1.9	-1.6	0.0	0.1	1.9	0.5	-0.7	-1.4	-0.8	0.9	0.5	2.4	1.6	0.7	-0.8	-2.0	-1.0
Basal cell carcinoma (self-reported)	1.2	1.4	3.7	-1.3	-1.7	-0.3	-1.0	-1.2	-1.9	-1.0	-0.8	-0.4	-1.0	-1.4	-1.5	-1.6	-1.2	-1.5	0.7	0.4	0.3
Ulcerative Colitis	1.1	1.5	4.8	0.8	2.2	0.8	1.3	0.1	1.4	-1.7	1.4	1.0	0.9	1.9	1.7	1.4	0.7	1.2	-0.5	0.0	-0.2
Pack years adult smoking proportion	1.1	1.7	7.8	-0.5	1.3	-2.1	-0.9	-1.5	0.7	-0.6	-1.3	-1.8	-1.6	0.4	-0.5	1.3	0.7	-0.7	-1.0	-2.8	-0.3
Falls in the last year	1.1	1.5	7.0	0.5	0.8	-1.2	1.3	1.1	1.6	2.6	-0.5	-1.1	-0.3	0.1	0.2	1.4	-0.5	1.0	-1.4	-2.4	0.0
Standing height	1.1	11.2	26.0	-3.1	-4.7	-3.3	-3.6	-0.5	-2.9	2.5	-4.2	-3.1	-3.3	-5.1	-4.5	-3.2	0.0	-3.4	3.4	1.1	-3.5
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.8	3.5	1.4	1.4	1.2	0.7	1.4	1.6	0.4	1.6	1.0	0.8	1.6	1.9	1.8	-1.3	1.5	-1.0	-0.3	1.5
Birth weight	1.1	2.4	10.8	-0.7	-1.9	-2.0	-0.5	-0.2	-0.9	0.1	-2.2	-1.9	-1.8	-2.2	-1.9	-0.7	-3.3	-1.2	0.5	-0.5	-1.2
Osteoporosis (self-reported)	1.1	1.4	4.1	-1.1	-1.6	-0.6	-0.3	0.7	-1.3	2.0	-1.0	-0.8	-0.2	-2.0	-1.6	-1.5	-0.7	-0.9	0.9	1.1	-0.6
Medication: Blood pressure	1.1	2.2	6.9	1.1	1.2	2.2	1.4	1.2	0.9	-0.8	2.6	2.2	1.4	2.1	2.1	0.6	-0.5	1.3	0.1	1.4	0.5
Diastolic blood pressure, automated reading	1.1	3.5	9.6	-1.7	0.1	-2.9	-2.7	-1.8	0.3	-1.0	-2.2	-2.5	-3.1	-1.1	-1.3	0.8	0.2	-1.7	1.7	-0.4	-3.1
Ulcerative Colitis (UC)	1.0	1.9	6.0	0.8	2.3	1.1	1.0	-0.3	1.6	-0.7	1.9	1.2	1.1	2.5	2.1	1.6	0.4	1.4	-1.4	-0.2	0.2
Heel T-Score	1.0	7.7	50.4	1.5	3.2	2.2	-0.2	-0.6	1.9	-4.0	2.9	2.2	3.0	3.4	3.0	1.7	7.1	2.0	-0.3	0.7	0.3
Ever used hormone-replacement therapy (HRT)	1.0	1.3	2.8	1.4	1.0	1.6	1.2	1.4	1.0	-0.4	1.6	1.5	0.9	0.8	1.7	0.8	0.9	1.5	-0.6	-0.3	0.9
Systolic blood pressure, automated reading	1.0	3.0	9.9	-1.8	0.4	-3.1	-2.3	-1.8	0.4	-0.3	-2.1	-2.7	-3.1	-0.9	-1.1	0.9	-0.1	-1.5	0.5	-1.4	-1.8
Medication: Metformin	1.0	1.3	6.2	0.3	1.0	1.4	-0.2	0.0	0.6	-2.3	1.2	1.4	1.2	1.2	1.1	0.4	2.5	0.9	-0.1	0.8	-0.0
Medication: Atenolol	1.0	1.2	4.8	0.7	-0.1	1.9	-0.0	0.8	-0.2	-2.0	1.4	2.2	1.0	1.2	1.0	-0.3	-0.3	0.6	1.2	1.0	0.1
Sitting height	1.0	6.8	12.1	-3.0	-3.1	-2.7	-3.5	-1.8	-2.3	0.9	-3.1	-2.4	-2.4	-2.8	-3.4	-2.2	-2.3	-3.0	2.5	1.1	-2.7
Mouth/teeth dental problems	1.0	1.6	5.2	0.8	0.1	1.5	2.3	1.5	-0.4	-2.2	0.7	1.6	1.1	-0.4	0.5	-0.9	0.8	0.4	1.2	2.2	-1.1
Medication: Amlodipine	1.0	1.4	9.2	-0.7	-0.2	0.2	0.0	0.4	-0.6	-0.7	-0.1	0.5	0.2	-0.2	-0.4	-1.4	-1.6	-0.3	3.0	1.3	-2.6
Comparative body size at age 10	1.0	2.6	10.6	-1.5	0.5	-2.8	-1.6	-1.6	0.3	0.5	-1.8	-2.4	-2.0	-0.4	-0.9	0.9	-3.2	-1.1	-0.3	-2.2	-0.7
Mouth/teeth dental problems: Loose teeth	1.0	1.2	2.8	-1.0	-1.1	-1.4	-1.2	-1.2	-0.6	0.4	-1.3	-1.2	-1.7	-1.1	-1.1	-0.5	-0.3	-1.2	1.3	-0.5	-1.5
Emphysema/chronic bronchitis	1.0	1.1	4.9	-0.6	0.3	-1.9	-0.3	-0.8	0.5	0.8	-1.3	-1.9	-1.3	-0.1	-0.6	0.9	-0.8	-0.5	-1.0	-2.2	0.0
Medication: Blood pressure	1.0	1.7	5.7	0.4	0.2	2.1	0.2	1.4	-0.4	-1.8	1.4	2.4	1.3	0.7	0.9	-1.2	-0.2	0.6	1.7	1.9	-1.0
Eye problems/disorders: Glaucoma	1.0	1.2	7.2	-0.2	0.2	1.5	-0.1	-0.3	-0.6	-1.4	1.0	1.4	1.0	0.1	0.5	-1.1	0.4	-0.1	1.8	2.7	-0.3
Supplements: Fish oil (including cod liver oil)	1.0	1.3	4.7	0.7	0.5	-0.9	1.2	0.6	1.5	1.9	-0.1	-0.8	-0.6	0.6	0.5	1.5	-2.2	0.8	-1.4	-1.9	0.3
Age started oral contraceptive pill	1.0	1.2	3.0	-1.7	-1.7	-0.5	-1.0	-1.3	-1.4	-0.4	-0.9	-0.6	-1.3	-1.7	-1.3	-1.4	-0.7	-1.2	0.4	0.2	-0.1
Impedance of whole body	1.0	5.2	22.3	-0.5	-3.6	1.8	1.2	0.5	-3.3	-0.9	0.5	1.4	0.3	-2.2	-1.2	-4.3	1.5	-1.3	3.2	4.7	-0.7
HbA1C	0.9	1.0	4.1	0.3	1.5	0.4	-0.2	0.7	0.8	1.5	1.2	0.9	1.0	2.0	0.9	1.2	1.2	0.6	-0.2	-0.0	-0.1
Rheumatoid Arthritis	0.9	1.2	3.3	1.5	-0.5	1.7	1.4	1.8	0.4	-0.7	1.6	1.7	0.7	0.2	0.9	0.1	0.9	0.9	-0.0	0.7	1.1
Hypothyroidism (self reported)	0.9	2.2	8.4	1.6	1.4	2.1	0.4	2.9	1.2	-0.0	1.8	2.2	1.6	1.0	1.7	0.7	-1.1	1.7	0.1	-0.4	0.8
Townsend deprivation index at recruitment	0.9	1.3	3.7	0.9	1.3	0.2	0.4	0.1	1.4	0.2	1.2	0.1	0.4	1.8	1.6	1.9	0.1	1.0	-1.7	-0.9	1.6
Average weekly fortified wine intake	0.9	1.0	3.4	-1.0	-1.1	-1.1	-1.2	-0.9	-0.7	-0.9	-1.1	-1.1	-1.7	-0.9	-0.8	-0.3	-1.9	-1.0	0.0	0.0	-0.2
Supplements: Glucosamine	0.9	1.1	4.4	-0.8	-1.2	-0.9	-0.5	0.5	-0.5	2.1	-1.2	-1.0	-0.9	-1.5	-1.3	-0.6	-1.9	-0.6	-0.1	-0.8	0.3
Allergy	0.9	2.0	5.6	-1.5	-1.5	0.8	-1.7	-1.7	-2.1	-1.2	-0.1	0.4	0.1	-1.1	-0.9	-2.0	2.4	-1.4	1.0	2.0	-0.0
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	2.9	0.9	1.3	-0.5	1.7	0.3	1.4	0.7	0.2	-0.4	-0.0	0.7	0.8	1.6	-1.5	0.9	-1.5	-1.5	1.0
Happiness	0.9	1.1	3.9	-0.8	-0.9	-0.6	-0.7	-0.3	-0.9	1.1	-0.9	-0.5	0.0	-1.3	-1.1	-0.8	1.2	-1.0	2.0	1.2	-1.4
Illnesses of mother	0.9	1.1	3.5	-0.4	0.2	-1.7	-0.7	-1.1	0.1	1.4	-1.6	-1.8	-0.6	-0.5	-1.0	0.4	0.1	-0.5	-1.3	-1.9	0.5
Breastfed as a baby	0.9	1.1	4.8	-0.6	-1.4	-0.7	-0.8	-0.7	-0.8	-1.2	-1.1	-0.8	-1.1	-1.0	-1.1	-1.0	-2.2	-0.8	1.3	0.0	-0.6
Glaucoma (self-reported)	0.9	1.1	5.0	-0.2	0.1	1.7	0.1	0.3	-0.4	-1.4	1.4	1.6	0.6	0.4	0.9	-0.8	0.0	-0.0	1.7	2.2	0.1
Number of full brothers	0.9	1.2	6.5	-1.3	-0.2	-1.2	-2.5	-1.4	-0.3	-0.1	-1.2	-1.1	-1.6	-1.2	-0.8	0.1	0.2	-1.0	0.4	-1.0	-0.5
Pulse rate, automated reading	0.9	2.8	13.0	1.6	2.0	1.6	0.1	0.9	1.4	-3.6	1.7	1.8	1.7	1.9	1.7	1.0	2.8	1.2	0.1	0.5	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	3.1	-1.1	-0.9	-1.3	-0.6	-0.9	-0.9	1.8	-1.2	-1.3	-1.0	-1.4	-1.2	-0.7	-0.1	-1.1	0.3	-0.3	-0.0
Long-standing illness, disability or infirmity	0.9	1.4	3.9	1.3	1.6	1.0	0.4	2.0	1.5	0.1	1.1	1.2	1.1	1.3	1.4	1.1	1.2	1.6	-0.6	-0.9	0.4
Number of self-reported non-cancer illnesses	0.9	1.6	5.7	1.6	1.3	1.5	0.3	2.4	1.0	-0.3	1.7	1.8	1.4	1.1	1.5	0.5	0.0	1.3	0.5	0.8	0.8
Pain type(s) experienced in last month: Hip pain	0.9	1.1	5.5	0.7	1.1	-0.5	0.5	0.9	1.3	1.6	-0.0	-0.5	0.1	0.7	0.6	1.4	1.2	0.9	-1.3	-2.3	0.4
Pack years of smoking	0.9	1.4	6.9	-0.4	1.3	-1.9	-0.7	-1.2	0.8	-0.4	-1.1	-1.7	-1.5	0.5	-0.3	1.3	0.5	-0.5	-1.1	-2.6	-0.3
Prostate Cancer	0.8	1.2	3.2	1.5	1.2	1.1	0.8	1.8	1.2	0.0	1.0	1.3	0.9	1.1	1.1	0.9	-0.3	1.4	-0.3	-1.1	0.4
Neuroticism (2016)	0.8	1.2	3.3	1.1	1.2	-0.1	1.1	1.5	1.8	1.8	0.4	0.3	0.4	0.9	0.7	1.4	-1.5	1.2	-0.5	-1.0	-0.3
Allergy or Eczema	0.8	2.0	13.3	1.5	0.9	-0.4	2.1	1.3	1.5	1.5	0.3	-0.2	-0.0	1.2	1.0	1.7	-3.7	1.1	-0.9	-1.4	0.1
Lung FEV1/FVC ratio	0.8	4.2	7.7	-2.1	-2.4	-1.8	-1.8	-1.5	-2.3	1.5	-2.4	-1.9	-1.2	-2.8	-2.6	-2.1	2.3	-2.3	2.3	0.5	-1.7
Maternal smoking around birth	0.8	1.1	4.5	0.4	1.6	-0.9	-0.0	-0.3	1.7	0.3	-0.4	-0.7	-0.2	0.9	0.3	1.7	2.1	0.7	-0.5	-1.4	-1.1
Fluid intelligence score	0.8	1.7	4.9	-1.2	-2.2	0.4	-0.6	-0.5	-2.1	1.3	-0.3	0.1	-0.1	-1.4	-1.1	-2.0	-1.2	-1.3	1.3	2.2	-0.2
Asthma	0.8	1.6	4.6	1.1	1.8	-0.8	0.9	1.1	2.1	1.9	0.2	-0.6	0.2	1.0	1.0	2.1	-0.6	1.2	-1.3	-1.8	-0.0
Lung cancer (father)	0.8	0.9	3.4	-0.4	0.3	-1.0	-1.5	-1.8	-0.2	-1.6	-0.4	-1.2	-1.5	-0.1	-0.2	0.3	-0.1	-0.7	-1.0	-0.9	0.6
Medication: Paracetamol	0.8	1.3	4.9	-0.8	-0.4	-1.8	-0.3	-0.7	0.0	2.2	-1.5	-1.8	-1.8	-1.0	-1.0	0.1	-1.0	-0.6	-0.3	-1.6	-0.2
Chronic bronchitis/emphysema (mother)	0.8	0.9	4.0	0.4	1.8	-0.7	-0.5	-0.4	1.4	-0.9	0.1	-0.4	-0.1	0.9	0.6	1.5	0.7	0.6	-1.1	-2.0	-0.1
Qualifications: College or University degree	0.8	2.6	11.0	1.2	1.1	2.5	1.3	1.1	0.1	0.5	2.1	2.4	2.2	1.1	1.5	0.2	3.3	1.1	-0.7	1.5	1.4
Comparative height size at age 10	0.8	4.5	14.8	-1.2	-1.9	-2.8	-1.9	-0.2	-0.5	-0.8	-3.2	-2.1	-2.2	-2.8	-2.7	-1.1	0.3	-1.6	3.2	-0.5	-3.9
Medication: Aspirin	0.8	1.1	5.2	-0.4	0.7	1.1	-1.9	-1.0	-0.5	-2.3	1.1	1.1	0.3	1.4	0.7	-0.2	0.7	-0.4	0.8	1.2	0.2
Smoking status: Previous	0.8	1.2	12.6	0.4	-0.3	0.1	0.7	0.5	0.3	3.5	0.0	-0.2	0.1	0.2	0.1	0.4	-2.1	0.5	-0.8	-0.8	1.3
Commuting to job workplace: Walk	0.8	0.9	6.7	1.1	-0.1	1.1	2.6	1.3	0.3	-0.1	0.8	1.3	0.8	0.4	0.7	0.1	0.4	1.0	0.0	0.0	0.4
Guilty feelings	0.8	1.2	3.4	0.9	1.5	0.2	0.1	1.4	1.8	0.1	0.8	0.4	0.4	0.8	1.2	1.7	-0.5	1.5	-1.0	-1.6	0.4
Mother’s age at death	0.8	1.0	3.0	0.6	-0.3	1.7	1.5	1.1	-0.5	-0.4	1.2	1.7	1.5	0.2	0.6	-0.6	1.0	0.6	0.0	1.1	1.0
Average weekly beer plus cider intake	0.8	1.2	7.7	-0.9	0.5	-1.1	-1.7	-0.4	-0.2	2.8	-0.2	-1.1	-0.2	0.0	-0.4	0.7	0.9	-0.9	-0.8	-1.3	1.6
Arm predicted mass (left)	0.8	4.0	16.2	-0.2	1.3	-3.3	-2.1	-0.1	2.5	1.3	-2.5	-2.7	-2.0	0.1	-0.7	2.9	-0.4	0.2	-1.1	-4.0	-1.9
Triglycerides	0.7	1.1	3.3	0.7	1.5	-1.0	-0.2	-0.7	1.6	0.7	-0.3	-0.7	-0.0	1.4	0.5	1.8	1.6	0.7	-0.2	-1.1	-1.3
Taking other prescription medications	0.7	1.0	4.0	0.8	1.2	1.2	0.6	2.0	1.1	-0.7	1.1	1.4	0.7	1.1	1.2	0.6	0.3	1.2	0.5	-0.2	-0.6
High blood pressure (mother)	0.7	0.9	4.5	0.3	-0.7	1.3	0.3	0.8	-0.3	0.1	0.8	1.5	0.0	0.1	0.3	-0.8	-0.5	0.3	2.1	1.7	-1.4
Waist circumference	0.7	2.7	8.3	1.9	2.3	0.5	0.1	1.5	2.9	-0.7	1.0	0.8	0.7	2.2	1.9	2.6	1.1	2.2	-1.3	-1.7	0.7
Trunk fat-free mass	0.7	4.0	12.3	-1.0	0.1	-3.5	-2.7	-0.4	1.3	1.8	-3.0	-3.0	-2.3	-1.0	-1.6	1.7	-1.0	-0.7	-0.4	-3.2	-2.0
Prospective memory result	0.7	0.9	2.2	-0.5	0.1	-1.2	-1.5	-1.2	-0.5	-1.3	-0.9	-1.1	-0.7	-0.6	-0.9	-0.4	0.7	-0.9	0.8	0.4	-1.4
Pulse wave Arterial Stiffness index	0.7	0.8	3.0	-0.6	-0.2	-1.3	-1.1	-0.3	0.1	-0.2	-1.0	-0.9	-1.5	-0.7	-0.8	0.1	0.7	-1.0	1.3	0.1	-1.7
Trunk predicted mass	0.7	3.9	12.0	-0.9	0.1	-3.5	-2.7	-0.4	1.3	1.8	-3.0	-3.0	-2.3	-1.0	-1.6	1.7	-0.8	-0.6	-0.4	-3.2	-2.1
Headache pain in last month	0.7	1.3	3.8	0.8	1.7	0.2	-0.2	0.3	1.3	1.0	0.6	0.1	0.3	0.7	1.1	1.3	1.4	1.1	-1.9	-1.8	1.5
Arm fat-free mass (right)	0.7	3.5	11.4	-0.6	0.8	-3.2	-2.5	-0.1	1.9	0.9	-2.6	-2.6	-2.2	-0.5	-1.1	2.3	-0.2	-0.2	-0.6	-3.4	-2.0
Angina (self-reported)	0.7	1.0	4.7	0.1	1.3	0.4	-1.3	-0.2	0.4	-2.2	1.0	0.8	-0.2	1.6	1.2	1.2	1.1	0.2	-0.1	-0.2	0.3
Migraine (self-reported)	0.7	0.9	2.3	1.1	0.9	0.9	1.5	0.9	0.9	1.4	1.1	0.9	0.2	1.3	1.2	0.8	-0.2	1.0	-0.7	-0.3	0.6
Chest pain or discomfort	0.7	1.1	3.0	0.9	1.4	0.4	0.0	0.5	0.9	-0.9	0.9	0.3	0.3	1.2	1.1	1.3	1.3	0.9	-1.6	-1.1	1.7
Back pain experienced in last month	0.7	1.0	6.1	-0.3	-0.3	-1.5	0.2	-0.6	0.3	2.5	-1.3	-1.7	-0.7	-0.7	-0.9	0.2	0.3	-0.4	-0.7	-1.1	-0.3
Hearing aid user	0.7	0.8	4.0	-0.2	0.7	-1.0	-0.7	-1.2	0.9	0.4	-0.8	-1.1	-0.4	-0.1	-0.2	0.9	0.9	0.3	-1.2	-2.0	0.4
Alcohol drinker status: Never	0.7	0.8	3.6	-1.2	-0.4	-1.1	-1.0	-1.9	-0.5	-0.7	-0.8	-1.2	-0.8	-0.8	-0.9	-0.7	0.5	-0.8	-0.1	0.2	-0.5
Arm fat-free mass (left)	0.7	3.5	14.5	-0.1	1.4	-3.0	-2.2	0.3	2.5	0.9	-2.2	-2.4	-1.8	0.2	-0.6	2.8	-0.3	0.3	-1.0	-3.8	-1.8
Heart disease (siblings)	0.7	0.9	2.6	0.8	1.1	1.0	1.2	1.0	0.9	-0.1	1.3	1.1	0.6	1.6	1.4	0.9	-0.7	0.9	-0.3	-0.1	0.3
Neuroticism (Nagel 2018)	0.6	1.4	4.0	1.4	2.0	0.2	0.3	0.7	2.0	0.5	0.3	0.3	0.7	1.1	1.0	1.9	0.3	1.6	-1.2	-2.0	0.6
Irritable Bowel Disease (IBD)	0.6	1.4	3.3	0.6	1.8	0.8	1.0	-0.1	1.4	0.1	1.4	0.9	1.1	1.7	1.6	1.3	0.1	1.2	-1.8	-0.9	0.8
Verbal and Numeric Reasoning (VNR)	0.6	1.3	3.1	-1.6	-1.5	-0.2	-0.6	-0.2	-1.7	0.8	-0.6	-0.4	-0.3	-1.3	-1.0	-1.8	-1.5	-1.2	1.6	1.5	-0.4
Blood Eosinophil Count	0.6	4.8	11.7	2.7	2.6	0.3	2.2	0.4	3.1	-0.9	1.5	0.3	0.2	2.4	2.4	3.2	2.7	2.5	-3.4	-2.3	1.6
BMI	0.6	3.3	11.0	0.5	2.8	-2.0	-1.6	-0.4	3.0	0.1	-0.9	-1.3	-0.6	2.0	0.7	3.3	-1.6	1.0	-1.2	-3.3	-0.8
Angina	0.6	0.8	3.7	-0.1	1.2	0.3	-1.4	-0.2	0.4	-1.9	0.8	0.7	-0.2	1.5	1.0	1.2	0.9	0.2	-0.1	-0.3	0.4
Medication: Co-codamol	0.6	0.7	2.7	0.7	0.1	1.5	0.3	1.6	0.4	0.5	1.2	1.5	1.1	0.4	0.9	0.1	0.4	1.0	-0.1	0.1	0.7
Diabetes (mother)	0.6	0.7	7.5	0.4	1.3	-0.4	-0.3	0.2	0.8	-0.1	0.3	-0.4	0.3	0.2	0.6	1.2	2.7	0.1	-0.9	-0.4	0.4
Impedance of leg (right)	0.6	3.0	12.0	0.9	-2.1	2.0	2.2	1.4	-1.5	-0.4	1.0	1.7	0.6	-1.2	0.1	-2.6	2.2	0.2	2.3	3.5	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	8.2	0.6	1.1	0.5	0.4	-0.3	1.3	-1.3	1.0	0.4	0.8	1.7	1.4	1.4	2.9	1.1	-0.2	-0.4	-0.4
Hayfever, allergic rhinitis or eczema	0.6	1.4	9.9	1.1	0.8	-0.9	1.5	1.2	1.4	1.0	-0.2	-0.5	-0.4	0.5	0.5	1.4	-3.1	0.9	0.1	-1.1	-1.0
Chronic bronchitis/emphysema (father)	0.6	0.7	2.4	0.3	1.5	-0.3	-0.9	0.4	1.1	-1.6	0.0	-0.2	-0.2	0.6	0.6	1.2	0.4	0.4	-0.9	-1.4	0.5
Body mass index (BMI)	0.6	2.8	10.3	0.9	2.7	-1.3	-0.9	-0.1	2.9	-0.5	-0.2	-0.9	-0.4	2.0	1.1	3.2	-1.0	1.2	-1.9	-2.8	0.2
Number of incorrect matches in round	0.6	1.0	3.4	-1.0	-1.6	0.4	-0.6	0.4	-1.2	-0.3	0.1	0.4	-0.6	-1.1	-0.6	-1.5	-1.8	-0.8	1.4	1.6	-0.2
Hair/balding pattern: Pattern 3	0.6	0.9	3.4	0.8	1.2	0.4	1.1	0.7	1.1	-0.8	0.5	0.5	0.8	1.1	0.8	0.9	1.3	1.0	-0.6	-1.9	0.5
Pulse rate	0.6	1.0	5.3	0.4	0.7	0.5	-0.6	0.1	0.6	-2.0	0.5	0.9	0.7	0.9	0.5	0.1	2.3	0.3	1.5	0.8	-1.2
Mouth/teeth dental problems: Dentures	0.6	1.0	3.1	-0.8	-0.6	-1.2	-0.7	-1.3	-0.4	-1.0	-1.4	-1.4	-1.8	-1.2	-1.0	-0.3	-0.7	-0.8	0.2	-0.7	-0.8
Birth weight of first child	0.6	1.2	3.9	-0.0	-1.1	-1.7	0.5	-0.4	-0.0	1.1	-1.6	-1.6	-1.0	-1.2	-1.4	-0.3	-2.0	-0.4	-0.1	-0.5	-1.2
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	2.9	0.6	0.4	-0.4	-0.3	0.1	0.9	0.7	0.4	-0.4	-0.3	1.1	0.4	1.1	0.4	0.4	-1.5	-1.7	1.7
Medication: Ventolin 100micrograms inhaler	0.6	0.8	3.7	0.5	1.2	-0.6	0.7	0.4	1.2	1.9	0.1	-0.4	0.4	1.0	0.6	1.6	0.1	0.6	-1.0	-0.6	0.2
High blood pressure (siblings)	0.6	0.9	2.3	-0.8	-0.5	-0.8	-1.0	-1.5	-0.5	-0.4	-1.0	-0.9	-1.1	-1.0	-0.8	-0.5	-0.9	-0.9	1.1	0.9	-1.5
Leg fat percentage (right)	0.6	2.0	6.9	2.0	1.8	0.3	0.8	1.1	2.6	-1.2	0.7	0.6	0.3	2.0	1.7	2.2	-0.4	1.9	-0.7	-1.2	0.1
Wheeze or whistling in the chest in last year	0.6	1.1	5.6	0.3	1.4	-1.3	-0.5	0.3	1.6	-0.9	-0.3	-0.9	-0.6	1.3	0.5	1.6	-1.1	0.4	-0.5	-2.4	-0.4
Arm predicted mass (right)	0.6	3.3	10.0	-0.7	0.7	-3.2	-2.6	-0.3	1.6	1.1	-2.5	-2.6	-2.1	-0.6	-1.1	2.1	-0.3	-0.5	-0.5	-3.2	-1.8
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	2.7	-1.0	-1.0	-0.4	-0.2	-0.4	-0.7	-0.2	-0.6	-0.6	-0.1	-0.8	-0.7	-1.0	-0.5	-0.7	1.2	1.5	-1.6
Whole body fat-free mass	0.6	3.5	10.8	-0.9	0.3	-3.3	-2.8	-0.3	1.3	1.5	-2.7	-2.8	-2.2	-0.9	-1.5	1.8	-1.0	-0.7	-0.6	-3.1	-1.7
Leg fat-free mass (right)	0.6	3.0	8.9	-1.4	-0.0	-2.9	-3.0	-0.5	0.6	1.1	-2.5	-2.5	-2.1	-1.0	-1.6	1.2	-1.4	-1.0	-0.5	-2.5	-1.3
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	1.4	0.8	1.2	0.2	0.9	0.6	1.2	1.2	0.4	0.2	0.0	0.9	1.0	0.9	0.2	1.1	-0.8	-0.7	0.5
Whole body water mass	0.6	3.5	10.5	-0.9	0.3	-3.2	-2.8	-0.3	1.3	1.6	-2.7	-2.7	-2.1	-0.8	-1.5	1.8	-0.9	-0.6	-0.5	-3.1	-1.7
Leg predicted mass (right)	0.6	3.1	8.9	-1.4	0.0	-3.0	-3.0	-0.6	0.7	1.1	-2.5	-2.5	-2.1	-1.0	-1.6	1.2	-1.4	-1.0	-0.5	-2.5	-1.3
Average weekly champagne plus white wine intake	0.6	0.8	2.4	0.7	0.4	-0.7	1.5	0.5	1.5	0.6	-0.8	-0.8	-0.3	-0.1	-0.0	1.0	-1.1	1.0	-0.5	-1.0	-1.5
Ever taken oral contraceptive pill	0.6	0.6	2.1	0.2	0.0	1.1	0.2	0.5	-0.4	1.3	1.1	0.7	0.9	-0.0	0.6	-0.3	0.8	0.4	-1.4	0.8	1.4
Basal metabolic rate	0.6	3.5	11.2	-0.9	0.3	-3.3	-2.8	-0.4	1.3	1.4	-2.8	-2.8	-2.2	-0.8	-1.5	1.7	-1.0	-0.6	-0.5	-3.0	-1.8
Leg fat percentage (left)	0.6	2.2	8.1	1.8	2.1	-0.1	0.5	0.9	2.9	-1.3	0.5	0.4	0.1	2.2	1.7	2.5	-0.5	1.8	-0.6	-1.6	-0.5
Bipolar Disorder (2018)	0.5	0.7	3.8	-0.6	0.3	-0.8	-0.6	-0.7	0.1	0.7	-0.3	-0.9	-0.0	0.2	-0.2	0.7	-2.0	-0.1	-1.7	-1.2	1.2
Depression (Nagel 2018)	0.5	0.7	3.0	0.5	0.9	-1.2	-0.2	0.4	1.2	0.2	-0.8	-1.0	-0.7	0.1	-0.0	1.3	-0.5	0.5	-0.4	-1.7	-0.8
Schizophrenia vs Biploar Disorder	0.5	0.6	3.2	-0.2	-0.5	0.1	0.1	-0.1	-0.5	0.8	-0.2	0.2	-0.4	-0.4	-0.4	-0.7	1.3	-0.3	1.8	1.3	-1.4
Alzheimer’s Disease (including proxy)	0.5	0.7	2.0	-1.0	-1.4	-0.5	-0.2	-0.2	-0.8	0.0	-0.5	-0.7	-1.2	-1.1	-0.7	-1.0	-0.4	-1.0	0.9	1.1	-0.6
Reaction Time	0.5	0.9	13.1	-0.5	0.3	-0.2	-0.3	-0.6	-0.7	0.3	0.3	-0.2	-0.3	0.1	0.1	-0.1	3.6	-0.8	-0.1	0.1	0.7
Bipolar Disorder (2011)	0.5	0.4	4.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-2.2	-1.5	0.9
Neuroticism	0.5	1.3	2.6	1.6	1.6	1.3	0.4	1.0	1.3	0.2	1.1	1.3	1.6	1.2	1.3	1.2	-0.3	1.5	-0.8	-0.5	1.1
Chronotype (morning person)	0.5	1.2	5.8	0.1	0.9	1.2	-0.5	-0.9	0.2	-2.0	1.1	1.2	1.3	0.9	0.9	-0.0	2.4	0.3	0.6	1.2	0.1
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	5.0	0.1	0.3	0.4	0.4	0.9	0.0	1.2	0.3	-0.1	0.3	0.0	0.2	0.4	-0.3	0.5	-2.1	-0.5	2.2
Leg fat-free mass (left)	0.5	2.6	8.7	-1.2	-0.1	-2.7	-2.9	-0.4	0.5	0.9	-2.4	-2.3	-2.0	-1.1	-1.5	1.0	-1.3	-1.0	-0.4	-2.3	-0.9
Impedance of leg (left)	0.5	2.3	8.2	0.7	-1.8	1.6	2.1	1.3	-1.0	-0.2	0.8	1.4	0.5	-0.9	0.1	-2.0	2.4	0.2	2.3	2.9	-1.4
Leg predicted mass (left)	0.5	2.6	8.4	-1.2	-0.1	-2.7	-2.9	-0.4	0.5	0.9	-2.4	-2.3	-2.0	-1.2	-1.5	1.0	-1.3	-1.0	-0.4	-2.3	-0.8
Past tobacco smoking	0.5	0.9	8.2	-0.2	0.3	0.2	-0.5	-0.4	-0.3	-2.9	0.4	0.4	0.2	0.3	0.0	-0.4	2.3	-0.4	0.4	1.0	-0.8
Alcohol usually taken with meals	0.5	0.7	3.8	1.0	-0.6	1.3	1.1	2.0	0.4	-0.0	0.8	1.3	0.8	-0.2	0.5	0.1	-0.6	1.0	-0.1	0.5	0.7
Had other major operations	0.5	0.6	1.7	-0.2	0.8	-1.1	-0.8	-0.3	0.5	1.3	-0.9	-1.2	-0.6	-0.0	-0.2	1.1	-0.6	-0.1	-0.6	-1.1	-0.2
Father’s age at death	0.5	0.7	4.2	0.1	-0.8	1.1	0.4	0.7	-0.3	2.1	0.5	1.2	1.3	-0.5	0.0	-0.6	0.3	0.3	0.2	0.6	1.0
Pulse wave reflection index	0.5	0.6	2.6	-0.5	0.2	-1.1	-0.4	-0.2	0.4	1.6	-0.5	-1.0	-0.9	-0.0	-0.1	1.0	-1.6	-0.4	-0.5	-0.3	-0.6
Loud music exposure frequency	0.5	0.5	1.7	0.4	0.4	1.1	0.6	1.1	-0.1	0.5	0.8	1.1	1.3	0.7	0.5	-0.3	0.4	0.2	0.8	1.0	-0.4
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	3.1	0.6	0.5	-0.2	1.1	1.2	0.5	1.6	-0.2	-0.1	0.1	-0.0	0.0	0.4	1.6	0.5	-1.2	-1.7	0.8
Pulse wave peak to peak time	0.5	0.5	2.2	0.4	-0.1	1.0	0.9	0.4	-0.2	0.4	0.7	0.6	1.3	0.4	0.5	-0.2	-0.6	0.7	-1.1	-0.0	1.5
Medication: Omeprazole	0.5	0.6	1.7	-0.5	-0.6	-0.9	-0.2	-0.2	-0.4	1.2	-1.2	-0.9	-0.4	-1.3	-1.1	-0.6	-0.7	-0.5	0.5	-0.6	-0.6
Heart disease (mother)	0.5	0.6	2.2	0.5	0.4	1.0	1.5	0.1	0.6	-0.5	1.4	0.8	0.2	1.3	1.2	0.5	0.1	0.7	-0.2	0.3	0.5
Alcohol intake frequency.	0.5	1.1	3.4	0.6	1.2	1.5	0.5	0.1	0.7	-1.0	1.3	1.6	1.8	1.2	1.1	0.2	0.7	0.9	0.7	1.3	-0.4
Overall health rating	0.5	1.0	3.0	0.9	1.5	0.5	0.3	0.8	1.2	-1.1	0.6	0.8	0.8	1.3	1.0	1.0	1.3	1.0	-0.4	-1.7	0.3
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.0	0.4	1.4	-0.1	1.0	-0.3	1.1	1.4	0.3	-0.1	0.9	1.2	0.7	0.9	0.4	0.7	-0.7	-0.4	-0.4
Ever had bowel cancer screening	0.5	0.6	2.4	0.8	-0.7	1.4	0.8	1.5	0.0	-0.1	1.0	1.3	0.7	0.2	0.6	-0.4	-0.1	0.6	0.6	0.4	0.2
Asthma (self-reported)	0.5	1.1	3.3	0.8	1.4	-1.0	0.8	0.7	1.7	1.8	-0.1	-0.9	-0.0	0.6	0.6	1.6	-0.7	0.7	-0.9	-1.4	-0.3
Medication: Gliclazide	0.5	0.6	2.4	0.2	0.5	1.1	0.6	-0.2	0.3	1.0	0.7	1.1	0.8	1.0	0.6	-0.1	1.6	0.6	0.8	0.6	-0.6
Medication: Atorvastatin	0.5	0.6	3.3	0.1	0.8	0.9	-0.6	-0.0	0.3	-1.8	0.8	0.9	0.3	0.7	0.8	0.2	0.2	0.4	0.8	1.0	-0.7
Cholesterol lowering medication	0.5	0.8	3.3	0.6	1.0	1.1	-0.1	-0.3	0.6	0.5	1.4	0.9	0.7	1.5	1.2	0.6	1.8	0.7	-0.1	0.5	0.4
Bipolar Disorder or Schizophrenia	0.4	0.9	2.6	-0.5	0.0	-1.5	-0.7	-0.7	0.3	0.8	-1.2	-1.6	-1.2	-0.7	-0.8	0.6	-1.6	-0.3	-1.0	-1.3	0.2
Ovarian Cancer	0.4	0.5	2.8	0.4	1.2	0.2	-0.1	0.9	0.7	-0.1	0.3	0.6	-0.0	0.4	0.7	0.7	1.7	0.6	-0.0	-1.2	-0.2
Crohns Disease (2012)	0.4	0.6	2.1	-0.7	-1.4	0.2	0.3	-0.2	-1.2	0.8	-0.1	0.1	-0.3	-1.1	-0.7	-1.4	-1.4	-0.6	0.2	0.3	0.7
Blood Platelet Count	0.4	5.1	10.2	3.0	2.2	2.0	3.2	1.5	2.6	-0.8	2.5	1.7	1.6	2.4	2.8	2.4	-1.3	3.0	-2.8	-0.5	1.9
Blood Red Count	0.4	3.7	13.6	-1.8	-0.4	-1.6	-2.6	-2.3	-0.4	-3.7	-1.2	-1.2	-1.6	-0.4	-1.0	-0.6	-0.7	-1.6	3.3	1.2	-3.6
Severe depression (siblings)	0.4	0.4	0.9	1.0	0.6	0.5	0.6	0.9	0.9	-0.4	0.6	0.6	0.0	0.6	0.7	0.9	-0.5	0.9	-0.2	-0.9	0.1
Relative age voice broke	0.4	0.5	2.6	0.6	-0.2	1.2	0.7	0.9	-0.3	0.4	0.8	0.8	0.2	-0.6	0.6	-0.6	-0.5	0.5	-1.0	0.0	1.6
Age when periods started (menarche)	0.4	1.1	2.9	-1.0	-1.1	-0.4	-0.8	-0.5	-1.7	1.4	-0.6	-0.6	-0.9	-1.5	-0.9	-1.3	-1.0	-1.3	0.1	1.2	0.1
Hair/balding pattern: Pattern 2	0.4	0.5	2.4	0.1	-0.2	0.9	-0.1	0.2	-0.7	-0.7	0.6	0.7	0.6	-0.4	0.2	-0.5	0.7	-0.1	-0.3	1.6	1.4
Had menopause	0.4	0.5	3.0	-0.4	-0.3	-0.7	-0.2	0.3	0.2	0.0	-0.2	-0.5	-1.3	-0.2	-0.2	0.4	-1.6	-0.2	-0.1	-1.7	0.4
Neuroticism score	0.4	0.9	3.0	1.2	1.7	0.4	-0.1	0.6	1.3	0.3	0.6	0.5	1.1	1.0	1.0	1.5	0.1	1.2	-0.8	-0.9	0.8
Weight	0.4	2.1	6.8	-0.4	0.5	-2.6	-2.3	-0.2	1.5	0.5	-2.0	-2.1	-1.8	-0.2	-0.8	1.7	-0.9	-0.2	-0.2	-2.2	-1.5
Hip circumference	0.4	1.6	9.1	-0.4	-0.3	-1.9	-1.6	-0.1	0.7	0.7	-1.5	-1.5	-1.5	-0.4	-0.8	0.7	-3.0	-0.4	0.6	-0.5	-1.6
Worrier / anxious feelings	0.4	0.8	1.6	1.0	1.3	0.5	0.9	0.8	1.2	0.3	0.7	0.5	1.1	0.9	0.9	1.2	0.7	1.0	-1.2	-0.5	0.8
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.4	1.9	0.1	0.8	-0.4	-0.5	0.6	0.4	0.9	-0.1	-0.4	-0.4	0.2	0.4	1.0	-0.0	-0.0	-1.1	-1.4	1.0
Medication: Cholesterol lowering	0.4	0.6	3.7	-0.7	0.4	-0.6	-1.9	-1.1	-0.2	-1.2	-0.5	-0.5	-0.5	0.5	-0.2	0.1	0.4	-0.6	0.6	0.1	-0.8
Exposure to tobacco smoke at home	0.4	0.4	1.8	-0.1	0.5	-1.1	-0.2	-0.2	0.8	0.3	-1.1	-0.9	-0.8	-0.3	-0.4	0.7	-0.8	-0.1	0.2	-1.3	-0.4
Peak expiratory flow (PEF)	0.4	0.9	3.9	1.2	0.8	0.0	1.3	0.4	1.2	2.0	0.2	-0.0	0.7	0.8	0.4	1.0	-0.2	0.8	-1.0	-1.7	0.5
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	5.5	0.9	-0.0	-0.3	1.4	0.9	0.7	2.3	0.1	-0.4	0.1	0.0	0.1	0.9	-0.1	0.5	-1.0	-0.9	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	1.4	0.8	1.1	0.6	0.1	0.1	1.1	-0.7	0.6	0.6	0.1	1.0	1.1	1.2	-0.7	1.0	-0.3	-0.6	0.2
Health satisfaction	0.4	0.6	2.2	0.1	0.8	-0.9	-0.0	-0.3	1.0	-1.0	-0.8	-0.7	-0.5	0.4	0.0	1.0	-0.2	0.3	0.6	-1.0	-1.5
Medication: Ibuprofen	0.4	0.4	1.9	-0.5	-0.1	-0.7	-0.8	0.6	-0.3	1.4	-0.5	-0.7	-0.6	-0.6	-0.3	0.1	-0.9	-0.6	-0.4	-0.8	0.9
Mean time to correctly identify matches	0.4	0.7	7.3	-0.8	-0.0	-0.2	-0.7	-0.7	-1.0	-0.1	0.2	-0.2	-0.6	0.1	-0.2	-0.2	2.7	-1.1	0.6	0.0	0.7
Leg fat mass (right)	0.4	1.4	5.5	1.0	1.5	-1.2	-0.7	0.5	2.3	-0.6	-0.6	-0.7	-0.8	1.1	0.6	2.3	-0.4	1.0	-0.6	-2.0	-0.7
Had major operations	0.4	0.4	2.5	-0.1	0.1	-0.4	-0.5	-0.1	0.1	1.6	-0.6	-0.7	-0.5	-0.8	-0.2	0.4	-0.2	-0.1	-0.9	-0.8	1.0
Hypertension (Self-reported)	0.4	1.2	3.5	0.7	1.1	1.7	-0.0	1.2	0.6	-1.1	1.9	1.8	0.8	1.2	1.6	0.2	-0.2	1.0	0.5	1.0	0.2
Friendships satisfaction	0.4	0.6	2.4	-0.8	-0.2	-1.1	-0.6	-0.3	-0.2	0.0	-0.9	-0.9	-0.1	-0.7	-0.9	-0.2	0.9	-0.6	1.0	0.3	-1.5
Smoking status: Current	0.4	0.7	5.1	-0.3	0.3	-0.5	-0.7	-0.7	-0.2	-2.2	-0.9	-0.4	-0.9	-0.7	-0.5	-0.3	0.1	-0.4	1.1	-1.0	-1.1
Miserableness	0.4	0.7	3.7	-0.0	1.0	-1.0	-0.3	-0.8	0.8	1.9	-0.5	-1.0	-0.2	0.3	0.2	1.4	-0.6	0.1	-0.8	-0.9	0.3
Wears glasses or contact lenses	0.4	0.5	1.9	1.0	0.3	0.4	1.4	1.1	0.6	0.5	0.5	0.6	0.9	0.8	0.5	0.6	-0.5	0.6	0.3	0.1	-0.2
Ever smoked	0.4	0.7	7.1	-0.1	-0.6	0.1	0.2	0.4	-0.4	2.0	-0.4	-0.1	0.0	-0.8	-0.3	-0.4	-2.7	-0.0	0.2	-0.2	0.7
Commuting to job workplace: Cycle	0.4	0.5	1.2	-0.2	-0.6	0.9	-0.3	-0.3	-1.1	-0.2	-0.0	0.8	0.8	-0.9	-0.4	-1.0	0.8	-0.6	0.8	0.8	0.8
Vascular/heart problems diagnosed by doctor	0.4	1.2	3.7	-0.7	-1.6	-1.1	0.8	-1.0	-1.1	1.9	-1.5	-1.4	-0.2	-1.4	-1.6	-0.7	0.3	-1.0	-0.7	-0.3	0.5
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.5	-0.3	-0.7	-0.7	-0.5	-0.0	-0.5	0.8	-0.9	-0.6	-0.7	-1.2	-0.9	-0.7	-0.5	-0.6	0.5	-0.6	-0.3
Supplements: Calcium	0.4	0.4	2.7	-0.2	0.2	-0.7	-0.1	1.0	0.4	1.6	-0.2	-0.8	0.3	0.0	0.1	0.9	-0.8	0.1	-1.1	-0.6	0.3
Leg fat mass (left)	0.4	1.7	6.3	0.9	1.6	-1.4	-0.9	0.5	2.5	-0.7	-0.8	-0.8	-0.9	1.2	0.6	2.5	-0.4	1.0	-0.5	-2.3	-1.1
Depressed Affect (Nagel 2018)	0.3	0.6	2.5	0.5	1.2	-0.7	0.0	-0.0	1.3	0.0	-0.6	-0.5	0.0	0.4	0.3	1.2	-0.7	0.8	-0.5	-1.6	-0.7
Schizophrenia (2018)	0.3	0.7	2.2	-0.2	-0.2	-1.3	-0.5	-0.4	0.2	0.5	-1.3	-1.3	-1.5	-1.1	-0.8	0.3	-0.5	-0.3	0.0	-0.8	-0.8
Fasting Glucose	0.3	0.4	2.0	-0.9	-0.3	-0.2	0.3	-0.1	-0.1	-0.1	0.3	-0.0	-0.6	-0.3	0.1	-0.3	-1.4	-0.5	1.1	0.9	-0.5
Systolic Blood Pressure	0.3	1.6	9.0	0.0	2.1	-0.7	-1.0	-0.2	1.5	-1.3	0.1	-0.3	-0.9	1.1	0.8	1.7	3.0	0.3	0.5	-1.0	-1.7
Frequency of depressed mood in last 2 weeks	0.3	0.5	2.2	0.2	1.0	-0.7	-0.3	-0.1	0.9	-1.1	-0.4	-0.6	-0.0	0.4	0.3	1.5	0.5	0.3	-0.5	-1.1	-0.6
Hearing difficulty/problems: Yes	0.3	0.5	2.2	0.8	0.3	1.1	0.6	0.5	0.7	0.3	0.5	1.2	0.8	0.7	0.6	0.4	1.5	1.0	-0.1	-0.5	0.0
Relative age of first facial hair	0.3	0.6	3.6	0.4	0.1	0.6	0.6	0.8	0.2	1.1	0.6	0.4	0.1	-0.5	0.4	-0.1	-0.2	0.5	-1.5	-0.3	1.9
Current tobacco smoking	0.3	0.5	5.2	0.0	0.5	-0.2	-0.4	-0.5	-0.0	-2.3	-0.6	-0.0	-0.6	-0.4	-0.2	-0.3	0.2	-0.1	1.0	-1.0	-0.8
Fed-up feelings	0.3	0.6	2.2	-0.2	1.0	-1.1	-0.9	-0.6	0.7	-0.8	-0.9	-1.0	-0.1	0.2	-0.2	0.9	-0.7	0.0	-0.4	-1.5	-0.6
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.3	-0.6	-0.2	-0.7	-0.4	-1.1	-0.3	-0.3	-0.9	-0.7	-0.3	-0.6	-0.8	-0.4	-0.1	-0.5	0.4	-0.4	-0.6
High blood pressure	0.3	0.8	1.9	0.4	0.9	1.2	-0.6	0.9	0.5	-1.4	1.4	1.4	0.2	0.9	1.2	0.1	-0.6	0.6	0.9	0.9	-0.4
Stomach or abdominal pain in last month	0.3	0.4	2.4	0.3	0.5	-0.2	0.1	0.0	0.1	-0.0	-0.0	-0.3	0.1	-0.2	0.0	0.3	1.1	0.2	-1.6	-0.8	1.5
Nervous feelings	0.3	0.6	2.5	-0.6	-0.9	0.5	-0.6	-0.6	-1.2	0.7	0.2	0.2	-0.2	-0.9	-0.3	-0.9	-0.9	-0.7	0.6	1.6	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.3	-0.2	0.7	-0.7	-0.9	-0.0	0.3	-0.6	-0.4	-0.6	-0.8	0.2	0.2	1.0	0.8	-0.1	-0.9	-1.1	0.2
Hearing difficulty/problems with background noise	0.3	0.6	1.7	0.4	0.3	1.3	0.7	1.1	0.3	-0.1	1.2	1.3	0.6	0.7	1.1	0.3	-0.1	0.7	-0.1	0.5	0.6
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	2.5	0.3	0.4	0.3	0.7	1.2	0.3	-0.6	0.4	0.2	-0.5	-0.1	0.5	0.4	-1.6	0.5	-0.2	-0.2	0.5
Alcohol intake versus 10 years previously	0.3	0.4	1.8	0.6	1.4	-0.3	-0.7	0.5	0.8	1.0	0.1	-0.2	0.5	0.8	0.5	0.8	-0.9	0.5	-0.2	-0.1	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	2.4	0.2	0.4	-0.4	-0.3	0.4	0.5	1.2	-0.0	-0.5	-0.2	0.1	0.2	0.9	0.8	0.3	-1.2	-1.6	0.8
Number of live births	0.3	0.4	1.4	-0.9	-0.4	-0.3	-0.8	-1.2	-0.1	-1.2	-0.6	-0.3	-0.5	-0.2	-0.3	0.2	0.6	-0.4	0.3	-0.4	-0.6
Arm fat mass (right)	0.3	1.1	3.3	0.3	1.2	-1.5	-1.4	-0.0	1.7	-0.0	-0.9	-1.1	-0.8	0.8	0.1	1.8	-1.0	0.4	-0.7	-1.7	-0.5
Length of working week for main job	0.3	0.4	1.7	-0.6	0.0	-0.7	-1.3	-0.8	-0.0	-0.3	-0.7	-0.6	-0.4	-0.3	-0.4	-0.2	0.5	-0.3	0.7	-0.4	-1.1
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.9	-0.3	0.9	-0.6	0.3	0.0	0.9	-0.1	0.2	-0.6	-0.2	0.7	0.6	0.9	-1.4	0.3	-0.8	-0.0	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.3	-0.4	-0.2	-1.0	0.3	-0.5	-0.1	0.4	-0.7	-1.1	-0.9	-0.3	-0.6	-0.2	-0.4	-0.5	-0.8	-0.9	0.5
Suffer from ‘nerves’	0.3	0.5	1.1	0.9	0.6	0.5	0.1	0.7	0.7	0.8	0.8	0.6	0.1	0.5	0.7	1.0	-1.0	0.7	-0.4	-0.2	0.9
Average weekly red wine intake	0.3	0.4	3.1	-0.2	-0.6	0.7	0.7	0.1	-0.8	-0.1	0.6	0.7	0.5	-0.3	0.2	-0.5	0.2	-0.3	0.5	1.8	-0.2
Breast cancer (self-reported)	0.3	0.4	1.0	-0.6	-0.4	-0.6	-0.5	-0.6	-0.8	0.4	-0.8	-0.5	0.2	-0.5	-1.0	-0.6	-1.0	-0.8	-0.1	-0.6	0.3
Medication: Paracetamol	0.3	0.5	2.2	-0.3	-0.2	-0.9	-0.1	-0.1	0.0	1.5	-0.9	-1.0	-0.9	-0.7	-0.6	0.1	-0.8	-0.2	-0.5	-1.2	0.3
Irritability	0.3	0.5	2.3	0.2	1.3	-0.4	-0.9	0.1	1.0	0.2	-0.6	-0.1	-0.1	0.2	0.1	1.1	0.6	0.6	0.2	-1.5	-0.7
Ever depressed for a whole week	0.3	0.4	1.9	0.7	0.2	0.8	0.5	1.3	0.3	-0.3	0.4	0.8	0.1	0.3	0.4	0.2	-1.4	0.6	0.5	-0.4	0.4
Alzheimer’s Disease (in mother)	0.2	0.3	1.1	-0.5	-0.5	-0.4	-0.3	1.0	-0.2	-0.0	-0.3	-0.5	-0.6	-1.0	-0.2	-0.1	-0.2	-0.3	-0.7	-0.1	1.0
Crohns Disease (2017)	0.2	0.4	2.3	-0.0	0.2	-0.0	0.5	-0.1	0.3	0.9	0.2	-0.1	0.2	0.1	0.2	0.3	-0.7	0.3	-1.5	-1.0	0.9
LDL Cholesterol	0.2	0.3	1.9	0.3	0.0	-0.3	-0.4	-0.4	0.4	-1.4	-0.0	-0.4	-1.1	0.3	0.3	0.4	-0.6	0.1	0.3	-0.5	-0.7
Primary Biliary Cirrhosis	0.2	0.3	1.1	-0.4	-0.8	-0.1	0.2	-0.2	-0.9	0.9	-0.1	-0.2	0.0	-1.0	-0.4	-0.7	0.6	-0.7	0.0	0.5	0.6
Smoking Status	0.2	0.5	5.7	-0.0	-0.3	-0.0	0.2	-0.1	-0.3	1.4	-0.3	-0.1	-0.5	-0.2	-0.3	-0.2	-2.4	-0.0	0.2	-0.7	0.3
Supplements: Zinc	0.2	0.2	0.9	0.3	-0.2	0.6	1.0	0.6	-0.0	0.4	0.5	0.5	0.6	0.2	0.3	-0.2	-0.9	0.2	0.2	0.7	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.9	0.5	0.7	-0.2	0.2	0.8	0.7	0.2	-0.0	-0.1	0.1	0.1	0.4	0.8	-1.0	0.4	-0.3	-0.8	0.0
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	2.1	0.0	-0.6	0.7	0.4	0.0	0.1	-0.6	0.2	0.7	0.4	-0.1	0.0	-0.3	1.5	0.3	0.8	-0.1	-0.4
Qualifications: None of the above	0.2	0.5	2.4	-0.6	-0.4	-0.7	-1.3	-0.6	-0.4	0.9	-0.3	-0.8	-0.5	0.0	-0.5	-0.1	-1.6	-0.8	0.2	-0.1	0.2
Medication: Simvastatin	0.2	0.3	1.2	-0.4	-0.3	0.3	-1.1	-0.9	-0.4	0.4	0.1	0.3	-0.1	0.2	-0.1	-0.6	0.6	-0.3	0.7	0.5	-0.4
Illnesses of siblings	0.2	0.3	0.9	-0.1	-0.9	0.2	0.2	0.3	-0.9	-0.1	-0.2	0.0	0.3	-0.5	-0.6	-0.9	0.4	-0.4	-0.3	0.4	0.8
Arm fat percentage (right)	0.2	0.6	2.0	0.8	1.1	-0.2	-0.6	0.2	1.4	-0.6	0.2	0.0	0.1	1.2	0.7	1.3	-1.0	0.8	-0.5	-0.6	0.4
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	3.6	-0.3	-0.6	0.0	-0.2	0.2	-0.9	1.7	-0.4	-0.1	1.0	-1.0	-0.8	-0.9	1.9	-0.5	0.2	0.3	-0.1
Qualifications: A levels/AS levels or equivalent	0.2	0.6	2.2	0.2	-0.8	0.7	1.2	1.4	-0.7	1.5	0.2	0.5	-0.0	-0.8	-0.1	-0.8	-0.1	0.1	-0.2	0.4	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	4.9	-0.3	-0.9	0.1	-0.1	-0.1	-0.9	1.0	-0.4	0.0	0.5	-1.2	-0.7	-1.0	2.2	-0.4	0.8	0.4	-0.8
Tense / ‘highly strung’	0.2	0.3	2.4	0.0	0.7	0.0	-1.5	0.1	0.3	0.6	0.4	0.2	-0.2	0.0	0.4	0.8	0.6	0.1	-0.2	-0.3	0.8
Gout (self-reported)	0.2	0.3	1.3	-0.8	0.2	-0.8	-0.2	-0.6	-0.2	-0.0	-0.8	-0.4	-0.1	0.1	-0.6	0.4	0.4	-0.6	0.8	-0.5	-1.1
Medication for pain relief, constipation, heartburn	0.2	0.3	1.0	0.6	-0.1	0.5	1.0	0.5	0.1	0.0	0.5	0.4	1.0	0.1	0.3	-0.1	0.7	0.6	-0.2	0.9	-0.2
Neck or shoulder pain in last month	0.2	0.3	1.1	-0.4	0.3	-0.6	-0.4	-1.0	0.1	0.9	-0.6	-0.7	-0.4	0.1	-0.3	0.1	1.0	-0.2	-0.7	-0.5	-0.3
Whole body fat mass	0.2	0.7	1.9	0.2	0.6	-1.3	-1.4	0.2	1.3	-0.6	-0.9	-0.8	-0.9	0.2	-0.1	1.2	-0.8	0.2	0.2	-1.0	-0.8
Mood swings	0.2	0.3	1.3	0.4	0.9	-0.1	-0.3	0.1	0.8	-1.2	0.0	0.1	0.3	0.7	0.4	1.0	0.2	0.4	-0.1	-0.2	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.6	0.4	0.5	0.5	0.8	0.3	0.5	0.2	0.3	0.6	0.7	0.7	0.5	0.2	-0.5	0.8	-0.3	0.1	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.3	1.7	0.3	0.3	0.5	0.9	-0.3	0.3	0.1	0.3	0.5	1.3	0.3	0.2	0.1	1.3	0.4	0.1	-0.1	-0.5
Arm fat mass (left)	0.2	0.9	2.5	0.2	1.0	-1.4	-1.4	0.0	1.5	-0.1	-0.9	-1.0	-0.8	0.7	0.0	1.6	-0.8	0.3	-0.4	-1.5	-0.5
Commuting to job workplace: Public transport	0.2	0.2	0.9	0.3	-0.6	0.0	0.2	0.2	0.1	-0.0	-0.4	0.2	-0.6	-0.7	-0.4	-0.0	-1.0	0.2	0.9	-0.5	-0.2
High cholesterol (Self-reported)	0.2	0.3	1.5	-0.0	-0.3	0.6	-1.1	-0.5	-0.6	-0.5	0.4	0.5	0.0	0.2	0.1	-0.6	0.6	-0.4	0.8	1.2	0.1
Illnesses of father: High blood pressure	0.2	0.2	1.2	-0.0	0.5	-0.2	-1.1	-0.5	0.2	-0.3	-0.0	-0.1	0.4	0.4	0.2	0.9	0.5	-0.0	-0.2	-0.4	-0.3
Number of operations (self-reported)	0.2	0.4	2.2	-0.1	0.4	-0.5	-0.7	0.1	0.5	1.5	-0.7	-0.5	-0.7	-0.4	-0.1	0.6	-0.6	0.1	0.3	-0.8	-0.6
Unable to work because of sickness or disability	0.2	0.2	1.1	0.1	0.8	-0.1	-0.5	0.8	0.5	-0.5	0.0	0.0	0.4	0.4	0.2	0.3	0.5	0.3	-0.5	-1.1	0.6
Intelligence (Savage-Jansen 2018)	0.1	0.2	1.8	-0.8	-0.2	-0.2	0.0	-0.3	-0.3	1.4	0.2	-0.3	-0.2	0.1	0.1	-0.3	-0.4	-0.3	-0.0	0.4	-0.1
Worry (Nagel 2018)	0.1	0.2	0.6	0.5	0.6	0.3	-0.1	0.1	0.4	0.3	0.3	0.4	0.5	0.1	0.2	0.5	-0.2	0.5	-0.3	-0.3	0.8
Schizophrenia (2014)	0.1	0.3	1.3	-0.2	-0.1	-0.6	-0.4	-0.2	-0.0	0.2	-0.7	-0.6	-1.1	-1.0	-0.5	-0.1	-0.4	-0.2	0.2	-0.3	-0.6
Lung FVC	0.1	0.3	2.1	0.1	0.6	0.3	0.5	-0.5	0.1	-0.7	0.3	0.4	0.6	0.2	0.3	0.5	1.4	0.0	-0.8	-0.7	0.7
Hair Pigment	0.1	2.6	5.5	-1.4	-2.4	-1.8	-0.7	-1.3	-1.7	0.3	-2.0	-1.9	-2.3	-2.1	-2.0	-1.4	-1.6	-2.0	0.9	0.3	-0.7
Number of treatments/medications taken	0.1	0.2	1.2	0.0	0.5	-0.2	-0.2	0.4	0.2	-0.3	-0.2	-0.0	-0.3	-0.1	0.0	0.0	-1.0	0.1	0.7	0.2	-1.1
Trunk fat percentage	0.1	0.2	1.3	0.3	-0.1	-0.2	-0.7	0.5	0.5	-1.1	-0.2	0.0	-0.4	0.0	0.0	0.1	-0.8	0.1	0.7	0.4	-0.2
Trunk fat mass	0.1	0.6	2.2	-0.0	0.0	-1.2	-1.5	0.3	0.8	-0.7	-1.0	-0.8	-1.0	-0.2	-0.4	0.5	-1.0	-0.1	0.6	-0.5	-0.9
Forced vital capacity (FVC)	0.1	0.3	1.6	-0.2	-0.5	-0.2	-0.4	-0.0	-0.5	1.1	-0.5	-0.2	0.6	-0.7	-0.7	-0.4	1.3	-0.3	0.0	0.0	-0.3
Noisy workplace	0.1	0.2	0.6	-0.1	0.2	-0.6	0.4	-0.1	0.2	-0.0	-0.8	-0.6	0.2	-0.6	-0.4	0.3	-0.2	-0.3	0.1	-0.4	-0.7
Hair/balding pattern: Pattern 4	0.1	0.3	3.2	-0.6	-0.3	-0.1	-0.5	-0.6	-0.3	0.3	0.2	-0.1	-0.2	0.4	0.1	0.1	-1.8	-0.4	0.0	0.5	0.4
Forced vital capacity (FVC), Best measure	0.1	0.5	3.5	-0.2	-0.7	-0.1	-0.1	-0.3	-0.6	0.5	-0.6	-0.2	0.2	-1.1	-0.7	-0.7	1.9	-0.3	0.7	0.2	-1.1
Body fat percentage	0.1	0.4	1.7	0.9	0.8	-0.1	-0.3	0.6	1.3	-1.2	0.2	0.2	-0.1	0.8	0.7	0.9	-0.6	0.8	0.1	-0.2	-0.1
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.9	-0.2	0.3	-0.1	-0.2	0.2	-0.1	0.5	0.2	-0.3	-0.3	0.0	0.2	-0.2	-0.6	-0.2	-0.5	0.9	-0.1
Supplements: Vitamin C	0.1	0.1	0.4	0.6	-0.3	0.4	0.2	0.3	0.3	-0.5	0.1	0.5	-0.1	-0.3	0.0	-0.1	0.1	0.3	0.5	0.5	-0.2
Illnesses of siblings: Diabetes	0.1	0.2	1.7	-0.3	0.5	0.1	-1.3	-0.3	0.0	-0.4	0.2	-0.0	0.0	-0.0	0.2	0.1	0.4	-0.1	0.0	-0.3	0.6
Arm fat percentage (left)	0.1	0.3	0.9	0.4	0.8	-0.3	-0.7	-0.1	0.9	-0.8	-0.0	-0.1	-0.2	0.8	0.4	0.8	-1.0	0.4	-0.1	-0.3	0.1
Qualifications: nursing, teaching	0.1	0.2	0.7	0.1	0.4	0.3	0.2	0.5	0.5	0.8	0.5	0.4	0.3	0.5	0.5	0.5	-0.3	0.4	-0.6	0.4	0.1
Tanning	0.0	0.1	0.5	-0.2	-0.3	0.1	-0.6	-0.5	-0.4	0.7	0.1	-0.1	0.1	0.1	-0.2	-0.3	0.4	-0.2	-0.4	0.1	0.7

Hub : Genes

ALS2CL

Models

Trait associations