[Hub]/) : Traits : Breast Cancer :

chr4:83,635,581-85,097,232

Best TWAS P=1.91e-09 · Best GWAS P=6.32e-09 conditioned to 0.142

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FAM175A 0.06 0.06 enet 7 0.06 8.9e-08 -5.4 5.7 1.1e-08 0.98 0.01 0.99 FALSE
2 CommonMind Brain Pre-frontal Cortex MRPS18C 0.15 0.12 enet 11 0.13 4.8e-15 -5.4 -5.9 4.0e-09 -0.91 0.01 0.99 FALSE
3 GTEx Muscle Skeletal MRPS18C 0.09 0.03 lasso 3 0.05 9.1e-06 3.9 -5.7 1.5e-08 -0.71 0.05 0.93 FALSE
4 GTEx Skin Sun Exposed Lower leg MRPS18C 0.14 0.12 enet 14 0.08 2.6e-07 5.8 5.2 1.5e-07 0.96 0.01 0.99 FALSE
5 GTEx Testis HELQ 0.15 0.10 enet 12 0.08 2.3e-04 5.5 5.3 1.3e-07 0.98 0.02 0.98 FALSE
6 NTR Blood MRPS18C 0.06 0.05 lasso 7 0.04 7.8e-14 -5.4 -5.8 8.6e-09 -0.97 0.01 0.99 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma MRPS18C 0.05 0.03 enet 9 0.06 3.2e-13 5.8 -5.8 7.3e-09 -0.86 0.00 1.00 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma MRPS18C 0.09 0.06 blup 29 0.08 3.0e-05 5.7 -5.7 1.4e-08 -0.84 0.00 0.98 FALSE
9 The Cancer Genome Atlas Glioblastoma Multiforme MRPS18C 0.16 0.05 blup 29 0.08 2.7e-03 5.7 -5.8 5.1e-09 -0.83 0.00 0.82 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MRPS18C 0.22 0.11 lasso 5 0.12 2.7e-13 3.9 -5.3 8.7e-08 -0.65 0.97 0.03 FALSE
11 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma MRPS18C 0.19 0.08 enet 10 0.12 1.6e-07 5.8 -5.6 1.9e-08 -0.86 0.00 1.00 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma MRPS18C 0.19 0.14 enet 11 0.20 8.3e-23 5.8 -5.6 1.7e-08 -0.82 0.00 1.00 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma MRPS18C 0.07 0.02 lasso 4 0.05 2.7e-06 5.7 -5.9 3.3e-09 -0.80 0.01 0.98 FALSE
14 The Cancer Genome Atlas Pancreatic Adenocarcinoma MRPS18C 0.10 0.12 enet 7 0.09 1.6e-04 5.7 -6.0 2.7e-09 -0.98 0.00 0.99 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma MRPS18C 0.28 0.08 lasso 4 0.17 4.6e-17 3.9 -5.9 3.5e-09 -0.78 0.02 0.98 FALSE
16 The Cancer Genome Atlas Soft Tissue Sarcoma MRPS18C 0.06 0.02 blup 29 0.03 1.0e-02 5.8 -5.7 1.2e-08 -0.79 0.01 0.64 FALSE
17 The Cancer Genome Atlas Thyroid Carcinoma MRPS18C 0.16 0.09 enet 8 0.20 4.4e-19 5.8 -6.0 1.9e-09 -0.83 0.00 1.00 TRUE