[Hub]/) : Traits : Coronary Artery Disease (CAD) : →

chr1:109,098,737-110,517,617

Best TWAS P=6.98e-10 · Best GWAS P=2.89e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Mucosa PSRC1 0.18 0.14 lasso 3 0.14 2.4e-09 -5.4 -5.9 3.5e-09 0.95 0.01 0.99 FALSE
2 GTEx Liver CELSR2 0.39 0.36 lasso 1 0.35 1.0e-10 -5.4 -5.4 6.5e-08 0.97 0.02 0.98 FALSE
3 GTEx Muscle Skeletal CELSR2 0.41 0.31 lasso 4 0.30 2.4e-30 -5.4 -5.3 1.4e-07 0.97 0.10 0.90 FALSE
4 GTEx Skin Sun Exposed Lower leg CELSR2 0.18 0.05 lasso 6 0.06 8.1e-06 -5.9 -5.5 5.0e-08 0.74 0.01 0.97 FALSE
5 GTEx Whole Blood PSRC1 0.14 0.04 lasso 3 0.03 6.9e-04 -6.2 -6.2 7.0e-10 0.97 0.00 1.00 TRUE
6 ROSMAP Brain Pre-frontal Cortex CELSR2 0.25 0.21 lasso 6 0.23 4.9e-29 -5.4 -5.6 2.4e-08 0.95 0.01 0.99 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma PSRC1 0.03 0.00 blup 49 0.02 5.7e-05 -5.9 -5.4 8.4e-08 0.79 0.02 0.92 FALSE
8 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma PSRC1 0.14 0.04 enet 13 0.07 2.7e-04 -6.1 -5.8 6.2e-09 0.73 0.01 0.83 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma PSRC1 0.07 0.06 lasso 1 0.04 1.8e-03 -5.9 -5.9 4.3e-09 0.77 0.01 0.83 FALSE
10 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PSRC1 0.12 0.11 lasso 4 0.09 4.5e-06 -6.0 -5.8 6.0e-09 0.95 0.00 0.99 FALSE
11 The Cancer Genome Atlas Liver Hepatocellular Carcinoma PSRC1 0.16 0.20 lasso 3 0.19 3.7e-09 -5.9 -6.1 1.0e-09 0.93 0.01 0.99 FALSE
12 The Cancer Genome Atlas Stomach Adenocarcinoma SORT1 0.04 0.01 blup 60 0.03 4.4e-03 -5.4 -5.3 1.3e-07 0.65 0.01 0.70 FALSE