[Hub]/) : Traits : Coronary Artery Disease (CAD) : ← →

chr2:202,952,678-204,788,156

Best TWAS P=3.92e-11 · Best GWAS P=1.76e-11 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ALS2CR8	0.12	0.08	lasso	11	0.11	1.2e-13	6.5	-5.4	5.6e-08	-0.86	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	ICA1L	0.09	0.06	lasso	2	0.06	1.9e-07	6.5	-6.4	1.8e-10	-0.98	0.01	0.99	FALSE
3	GTEx	Adipose Subcutaneous	NBEAL1	0.09	0.07	lasso	3	0.06	5.7e-06	6.6	-6.6	4.1e-11	-1.00	0.01	0.99	FALSE
4	GTEx	Adipose Subcutaneous	ICA1L	0.11	0.06	lasso	5	0.03	9.8e-04	6.6	6.6	4.7e-11	0.99	0.01	0.99	FALSE
5	GTEx	Adipose Visceral Omentum	NBEAL1	0.09	0.08	lasso	3	0.02	1.9e-02	6.6	-6.5	7.5e-11	-1.00	0.01	0.98	FALSE
6	GTEx	Artery Aorta	NBEAL1	0.28	0.20	lasso	7	0.18	6.4e-10	6.6	-6.4	1.6e-10	-0.99	0.01	0.99	FALSE
7	GTEx	Artery Coronary	NBEAL1	0.25	0.16	lasso	10	0.20	3.1e-07	5.6	-5.9	3.0e-09	-0.93	0.01	0.99	FALSE
8	GTEx	Artery Tibial	CARF	0.05	0.02	lasso	3	0.02	7.5e-03	6.6	-6.0	1.6e-09	-0.88	0.02	0.94	FALSE
9	GTEx	Artery Tibial	NBEAL1	0.24	0.29	lasso	6	0.29	1.1e-22	6.6	-6.6	4.8e-11	-1.00	0.00	1.00	FALSE
10	GTEx	Cells Transformed fibroblasts	CARF	0.11	0.11	enet	13	0.13	8.0e-10	3.4	-5.4	7.8e-08	-0.78	0.14	0.86	FALSE
11	GTEx	Cells Transformed fibroblasts	ICA1L	0.15	0.11	lasso	3	0.09	2.2e-07	6.6	6.6	5.0e-11	0.99	0.01	0.99	FALSE
12	GTEx	Muscle Skeletal	ICA1L	0.18	0.14	lasso	8	0.14	5.5e-14	6.6	6.4	1.8e-10	0.94	0.01	0.99	FALSE
13	GTEx	Nerve Tibial	NBEAL1	0.16	0.09	enet	21	0.14	4.4e-10	6.6	-5.7	1.2e-08	-0.78	0.01	0.99	FALSE
14	GTEx	Nerve Tibial	ICA1L	0.12	0.10	enet	11	0.09	3.2e-07	6.6	6.1	1.4e-09	0.96	0.01	0.99	FALSE
15	GTEx	Skin Not Sun Exposed Suprapubic	CARF	0.22	0.08	lasso	9	0.10	5.7e-06	5.6	-5.7	1.0e-08	-0.85	0.03	0.96	FALSE
16	GTEx	Skin Not Sun Exposed Suprapubic	NBEAL1	0.16	0.08	lasso	8	0.08	5.2e-05	6.6	-6.5	1.0e-10	-1.00	0.01	0.99	FALSE
17	GTEx	Testis	CARF	0.38	0.30	lasso	6	0.30	1.4e-13	6.6	-6.6	4.3e-11	-0.99	0.01	0.99	FALSE
18	GTEx	Thyroid	ICA1L	0.11	0.11	enet	7	0.10	3.8e-08	6.6	6.4	1.7e-10	0.99	0.01	0.99	FALSE
19	METSIM	Adipose	CARF	0.07	0.02	lasso	5	0.03	8.8e-06	3.6	-5.3	1.2e-07	-0.76	0.06	0.93	FALSE
20	METSIM	Adipose	ICA1L	0.11	0.04	bslmm	265	0.05	6.7e-08	6.6	5.6	2.5e-08	0.85	0.01	0.99	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	KRT8P15	0.05	0.03	lasso	4	0.04	3.7e-06	4.3	-5.7	9.3e-09	-0.88	0.02	0.98	FALSE
22	The Cancer Genome Atlas	Colon Adenocarcinoma	ICA1L	0.10	0.01	blup	59	0.02	1.6e-02	6.6	6.6	3.9e-11	0.95	0.00	0.96	TRUE
23	The Cancer Genome Atlas	Colon Adenocarcinoma	WDR12	0.08	0.04	lasso	5	0.01	7.0e-02	6.6	6.6	4.3e-11	0.99	0.00	0.97	FALSE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ICA1L	0.05	0.02	lasso	6	0.02	2.8e-03	4.4	5.3	1.0e-07	0.83	0.01	0.91	FALSE
25	The Cancer Genome Atlas	Lung Adenocarcinoma	WDR12	0.04	0.02	lasso	2	0.02	1.4e-03	5.6	5.2	2.5e-07	0.78	0.01	0.54	FALSE
26	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CYP20A1	0.20	0.03	enet	7	0.03	1.6e-04	3.8	5.5	4.7e-08	0.93	0.00	0.21	FALSE
27	The Cancer Genome Atlas	Thyroid Carcinoma	ICA1L	0.06	0.01	blup	59	0.02	6.9e-03	6.5	5.3	8.9e-08	0.87	0.01	0.93	FALSE