[Hub]/) : Traits : Crohns Disease (2012) : ← →

chr6:166,651,581-167,841,508

Best TWAS P=5.99e-13 · Best GWAS P=7.57e-12 conditioned to 0.188

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Brain Cerebellar Hemisphere	AL133458.1	0.29	0.00	enet	19	0.00	3.6e-01	-6.8	-7.2	6.0e-13	0.86	0.02	0.90	TRUE
5	GTEx	Esophagus Mucosa	RNASET2	0.29	0.31	lasso	9	0.32	1.6e-21	-6.8	-7.2	7.2e-13	0.90	0.02	0.98	FALSE
7	GTEx	Lung	RNASET2	0.21	0.13	lasso	10	0.13	4.0e-10	-6.8	-7.1	8.8e-13	0.95	0.02	0.98	FALSE
21	The Cancer Genome Atlas	Esophageal Carcinoma	RNASET2	0.17	0.11	lasso	3	0.09	8.7e-04	-6.8	-7.1	1.4e-12	0.89	0.02	0.93	FALSE
18	YFS	Blood	RNASET2	0.45	0.60	enet	24	0.61	1.8e-260	-6.8	-6.8	8.6e-12	0.99	0.02	0.98	FALSE
17	NTR	Blood	RNASET2	0.28	0.42	lasso	13	0.43	5.3e-155	-6.8	-6.8	1.0e-11	0.99	0.02	0.98	FALSE
2	GTEx	Brain Cerebellum	AL133458.1	0.42	0.32	lasso	6	0.31	1.0e-09	-6.8	-6.8	1.2e-11	0.75	0.02	0.98	FALSE
22	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RNASET2	0.09	0.08	lasso	2	0.08	2.9e-09	-6.8	-6.8	1.4e-11	0.78	0.02	0.98	FALSE
26	The Cancer Genome Atlas	Rectum Adenocarcinoma	RNASET2	0.14	0.19	lasso	3	0.15	2.1e-04	-6.7	-6.7	1.6e-11	0.77	0.02	0.73	FALSE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	RNASET2	0.07	0.05	lasso	4	0.04	5.1e-09	-6.8	-6.7	2.0e-11	0.77	0.02	0.98	FALSE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	RNASET2	0.24	0.15	lasso	3	0.14	5.6e-15	-6.7	-6.6	4.5e-11	0.75	0.02	0.98	FALSE
23	The Cancer Genome Atlas	Brain Lower Grade Glioma	RNASET2	0.05	0.03	lasso	3	0.03	9.2e-05	-6.8	-6.5	5.9e-11	0.92	0.02	0.96	FALSE
10	GTEx	Skin Sun Exposed Lower leg	RNASET2	0.32	0.23	enet	48	0.24	3.3e-20	-6.6	-6.5	8.4e-11	0.91	0.02	0.98	FALSE
12	GTEx	Stomach	RNASET2	0.22	0.12	lasso	6	0.16	6.5e-08	-5.2	-6.4	1.4e-10	0.68	0.03	0.96	FALSE
16	METSIM	Adipose	RNASET2	0.09	0.09	lasso	4	0.12	8.7e-18	-6.8	-6.4	1.4e-10	0.92	0.02	0.98	FALSE
6	GTEx	Esophagus Mucosa	FGFR1OP	0.10	0.07	lasso	4	0.03	4.4e-03	6.4	6.4	1.7e-10	-0.86	0.03	0.93	FALSE
11	GTEx	Skin Sun Exposed Lower leg	AL133458.1	0.13	0.08	enet	10	0.03	1.0e-03	-6.8	-6.3	3.3e-10	0.95	0.02	0.98	FALSE
15	GTEx	Whole Blood	AL133458.1	0.20	0.14	enet	7	0.18	1.4e-16	-6.7	-6.3	3.8e-10	0.93	0.02	0.98	FALSE
4	GTEx	Cells Transformed fibroblasts	AL133458.1	0.16	0.14	enet	13	0.14	1.7e-10	-6.6	6.2	6.0e-10	-0.94	0.02	0.98	FALSE
24	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RNASET2	0.13	0.09	lasso	9	0.10	1.4e-11	-6.7	-6.1	8.0e-10	0.77	0.03	0.97	FALSE
14	GTEx	Whole Blood	RNASET2	0.20	0.18	enet	23	0.18	3.4e-16	-6.8	-6.1	1.2e-09	0.94	0.02	0.98	FALSE
8	GTEx	Lung	AL133458.1	0.17	0.09	lasso	5	0.12	3.9e-09	-4.3	-5.9	3.1e-09	0.86	0.02	0.98	FALSE
3	GTEx	Cells Transformed fibroblasts	RNASET2	0.29	0.30	enet	31	0.29	1.0e-21	-6.6	5.9	3.2e-09	-0.96	0.02	0.98	FALSE
13	GTEx	Thyroid	RNASET2	0.16	0.06	enet	33	0.04	3.8e-04	6.4	-5.9	4.4e-09	0.69	0.04	0.96	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	RNASET2	0.14	0.07	enet	25	0.08	3.6e-05	6.7	-5.8	6.5e-09	0.67	0.03	0.97	FALSE
19	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	RNASET2	0.08	0.05	enet	12	0.07	2.0e-06	-6.8	-5.5	4.2e-08	0.78	0.02	0.98	FALSE