TWAS
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Traits
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Traits
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Crohns Disease (2012)
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chr9:116,849,447-118,266,112
Best TWAS P=7.62e-15 · Best GWAS P=2.46e-15 conditioned to 0.00716
116.8M
117M
117.2M
117.4M
117.6M
117.8M
118M
118.2M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
METSIM
Adipose
TNFSF15
0.05
0.06
lasso
3
0.06
5.4e-09
-7.3
-7.8
7.6e-15
0.82
0.21
0.79
TRUE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
TNFSF15
0.02
0.01
blup
54
0.01
7.6e-03
-7.3
-7.4
1.6e-13
0.74
0.01
0.55
FALSE