Best TWAS P=7.62e-15 · Best GWAS P=2.46e-15 conditioned to 0.00716
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | TNFSF15 | 0.05 | 0.06 | lasso | 3 | 0.06 | 5.4e-09 | -7.3 | -7.8 | 7.6e-15 | 0.82 | 0.21 | 0.79 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TNFSF15 | 0.02 | 0.01 | blup | 54 | 0.01 | 7.6e-03 | -7.3 | -7.4 | 1.6e-13 | 0.74 | 0.01 | 0.55 | FALSE |