[Hub]/) : Traits : Crohns Disease (2012) : ← →

chr9:138,558,883-140,031,290

Best TWAS P=4.98e-19 · Best GWAS P=4.37e-20 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	YFS	Blood	CARD9	0.22	0.37	lasso	5	0.39	1.3e-137	9.0	8.9	5.0e-19	0.97	0.01	0.99	TRUE
11	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	INPP5E	0.07	0.04	blup	54	0.07	6.0e-05	6.1	-8.4	4.2e-17	-0.82	0.05	0.82	FALSE
18	The Cancer Genome Atlas	Testicular Germ Cell Tumors	INPP5E	0.10	0.06	blup	54	0.08	8.1e-04	6.5	-8.0	1.7e-15	-0.83	0.04	0.66	FALSE
4	YFS	Blood	PMPCA	0.03	0.01	lasso	5	0.02	2.7e-07	6.9	7.9	2.1e-15	0.79	0.05	0.95	FALSE
12	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SDCCAG3	0.05	0.01	blup	61	0.01	5.9e-02	6.2	-7.9	3.4e-15	-0.85	0.03	0.57	FALSE
5	The Cancer Genome Atlas	Breast Invasive Carcinoma	SEC16A	0.02	0.00	blup	69	0.01	1.0e-03	6.6	-7.5	4.5e-14	-0.66	0.07	0.65	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	INPP5E	0.11	0.16	lasso	3	0.16	2.4e-15	7.4	-7.5	5.6e-14	-0.82	0.91	0.09	FALSE
9	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	INPP5E	0.03	0.01	blup	54	0.01	1.1e-02	7.4	-7.3	2.9e-13	-0.81	0.02	0.64	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	SNAPC4	0.13	0.05	enet	7	0.06	1.7e-07	4.8	-7.2	4.5e-13	-0.66	0.65	0.23	FALSE
3	YFS	Blood	INPP5E	0.33	0.55	lasso	6	0.57	2.9e-235	7.0	-7.1	1.4e-12	-0.71	1.00	0.00	FALSE
6	The Cancer Genome Atlas	Colon Adenocarcinoma	INPP5E	0.11	0.08	lasso	2	0.08	3.4e-05	7.0	-7.1	1.6e-12	-0.71	0.14	0.12	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	INPP5E	0.04	0.02	blup	54	0.03	4.4e-04	6.6	-6.9	5.6e-12	-0.67	0.24	0.30	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	SDCCAG3	0.08	0.05	lasso	2	0.05	3.3e-06	5.1	-6.9	7.0e-12	-0.75	0.42	0.53	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SDCCAG3	0.04	0.05	enet	6	0.04	5.1e-05	5.1	-6.7	1.7e-11	-0.73	0.48	0.47	FALSE
7	The Cancer Genome Atlas	Colon Adenocarcinoma	SDCCAG3	0.08	0.01	lasso	4	0.02	3.1e-02	5.1	-6.6	3.7e-11	-0.69	0.04	0.22	FALSE
1	NTR	Blood	SNAPC4	0.02	0.01	lasso	5	0.02	6.3e-07	6.9	-6.5	9.1e-11	-0.67	0.20	0.79	FALSE
16	The Cancer Genome Atlas	Prostate Adenocarcinoma	SEC16A	0.08	0.10	lasso	4	0.08	1.9e-08	6.0	-6.2	6.4e-10	-0.58	1.00	0.00	FALSE
8	The Cancer Genome Atlas	Colon Adenocarcinoma	SNAPC4	0.15	0.03	enet	12	0.05	1.0e-03	6.9	-6.0	2.1e-09	-0.45	0.07	0.14	FALSE
17	The Cancer Genome Atlas	Rectum Adenocarcinoma	DNLZ	0.75	0.03	enet	20	0.22	7.0e-06	1.6	-5.3	1.0e-07	-0.42	0.00	0.11	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	SDCCAG3	0.16	0.14	lasso	4	0.12	8.2e-12	5.1	-5.2	1.9e-07	-0.57	1.00	0.00	FALSE