TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Crohns Disease (2012)
:
←
→
chr10:34,607,015-36,198,981
Best TWAS P=1.76e-09 · Best GWAS P=1.08e-09 conditioned to 1
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
CUL2
0.02
0.02
blup
64
0.01
7.6e-02
5.9
-6.0
1.8e-09
-0.98
0.03
0.88
TRUE
1
GTEx
Cells EBV-transformed lymphocytes
CREM
0.15
0.12
enet
11
0.15
1.3e-05
5.9
-6.0
2.1e-09
-0.99
0.04
0.95
FALSE
2
GTEx
Cells Transformed fibroblasts
CREM
0.06
0.03
enet
3
0.03
1.6e-03
4.5
-5.9
3.4e-09
-0.86
0.05
0.82
FALSE
3
NTR
Blood
CUL2
0.04
0.09
lasso
13
0.09
4.4e-26
5.8
-5.8
6.5e-09
-0.99
0.04
0.96
FALSE