Best TWAS P=1.76e-09 · Best GWAS P=1.08e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | CREM | 0.15 | 0.12 | enet | 11 | 0.15 | 1.3e-05 | 5.9 | -6.0 | 2.1e-09 | -0.99 | 0.04 | 0.95 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | CREM | 0.06 | 0.03 | enet | 3 | 0.03 | 1.6e-03 | 4.5 | -5.9 | 3.4e-09 | -0.86 | 0.05 | 0.82 | FALSE |
| 3 | NTR | Blood | CUL2 | 0.04 | 0.09 | lasso | 13 | 0.09 | 4.4e-26 | 5.8 | -5.8 | 6.5e-09 | -0.99 | 0.04 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CUL2 | 0.02 | 0.02 | blup | 64 | 0.01 | 7.6e-02 | 5.9 | -6.0 | 1.8e-09 | -0.98 | 0.03 | 0.88 | TRUE |