TWAS
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Genes
Traits
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Traits
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Crohns Disease (2012)
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chr21:45,398,656-45,902,320
Best TWAS P=2.03e-09 · Best GWAS P=1.44e-13 conditioned to 7.65e-06
45.4M
45.5M
45.6M
45.7M
45.8M
45.9M
0
5
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Thyroid Carcinoma
ICOSLG
0.11
0.03
blup
68
0.08
5.6e-08
-5
-6
2e-09
-0.7
0.01
0.98
TRUE