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chr20:61,522,825-62,912,463

Best TWAS P=2.51e-11 · Best GWAS P=7.28e-11 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ARFRP1	0.07	0.07	lasso	3	0.06	5.3e-08	-6.39	6.7	2.5e-11	-0.96	0.01	0.99	TRUE
2	CommonMind	Brain Pre-frontal Cortex	STMN3	0.07	0.02	lasso	4	0.05	2.8e-06	-6.19	-5.7	1.2e-08	0.71	0.03	0.97	FALSE
3	GTEx	Brain Cerebellar Hemisphere	STMN3	0.39	0.08	lasso	5	0.22	2.1e-06	-5.67	-5.8	5.2e-09	0.65	0.11	0.72	FALSE
4	GTEx	Brain Cerebellum	STMN3	0.33	0.12	lasso	10	0.20	1.8e-06	-6.01	-5.9	3.5e-09	0.66	0.04	0.95	FALSE
5	GTEx	Brain Cortex	STMN3	0.25	0.09	lasso	7	0.11	6.8e-04	-6.16	-6.1	9.8e-10	0.73	0.06	0.82	FALSE
6	GTEx	Breast Mammary Tissue (Female)	GMEB2	0.36	0.06	lasso	4	0.05	1.2e-02	-5.97	-5.4	6.4e-08	0.61	0.08	0.55	FALSE
7	GTEx	Pituitary	STMN3	0.43	0.00	enet	8	0.06	1.1e-02	-0.78	-5.4	6.3e-08	0.55	0.05	0.38	FALSE
8	GTEx	Testis	RTEL1	0.19	0.06	lasso	5	0.14	8.0e-07	-6.16	-6.3	3.4e-10	0.62	0.07	0.86	FALSE
9	GTEx	Thyroid	SLC2A4RG	0.12	0.06	lasso	5	0.04	2.4e-04	-6.07	5.8	6.6e-09	-0.74	0.07	0.92	FALSE
10	GTEx	Whole Blood	STMN3	0.10	0.00	lasso	3	0.00	1.2e-01	-5.62	5.8	7.2e-09	-0.73	0.03	0.72	FALSE
11	YFS	Blood	LIME1	0.12	0.19	enet	15	0.19	5.3e-59	-6.47	-6.6	4.9e-11	0.98	0.01	0.99	FALSE
12	The Cancer Genome Atlas	Esophageal Carcinoma	GMEB2	0.16	0.04	blup	64	0.05	1.0e-02	2.00	5.2	1.5e-07	-0.49	0.02	0.21	FALSE
13	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	STMN3	0.02	0.02	blup	43	0.02	1.7e-03	-6.12	-5.9	2.7e-09	0.63	0.01	0.92	FALSE
14	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TNFRSF6B	0.03	0.01	blup	44	0.02	7.1e-04	-6.03	-6.2	6.3e-10	0.75	0.04	0.86	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC2A4RG	0.03	0.01	blup	48	0.02	2.4e-03	-6.03	5.8	7.7e-09	-0.69	0.04	0.69	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	LIME1	0.02	0.03	blup	47	0.02	6.2e-03	-6.16	-6.4	1.2e-10	0.84	0.03	0.67	FALSE
17	The Cancer Genome Atlas	Lung Adenocarcinoma	TNFRSF6B	0.02	0.01	enet	7	0.01	6.9e-03	-6.03	-6.7	2.6e-11	0.93	0.02	0.89	FALSE
18	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RTEL1	0.05	0.04	blup	56	0.03	4.2e-03	-5.62	-6.6	5.6e-11	0.88	0.01	0.78	FALSE
19	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	STMN3	0.07	0.01	blup	41	0.05	4.2e-04	-5.67	-5.5	4.2e-08	0.57	0.02	0.88	FALSE
20	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TNFRSF6B	0.05	0.02	blup	44	0.03	2.9e-03	-6.51	-5.9	3.6e-09	0.93	0.01	0.71	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	ARFRP1	0.03	0.02	lasso	2	0.02	1.2e-03	-6.39	6.4	1.3e-10	-0.98	0.01	0.96	FALSE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	LIME1	0.04	0.05	blup	47	0.05	9.0e-06	-6.44	-6.6	5.2e-11	0.97	0.01	0.99	FALSE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC2A4RG	0.05	0.01	blup	48	0.02	2.0e-03	-6.44	6.2	6.4e-10	-0.85	0.01	0.94	FALSE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZGPAT	0.05	0.06	lasso	3	0.06	5.5e-07	-6.19	6.5	9.0e-11	-0.83	0.03	0.96	FALSE
25	The Cancer Genome Atlas	Testicular Germ Cell Tumors	LIME1	0.10	0.02	blup	47	0.04	1.5e-02	-6.44	-6.6	5.2e-11	0.90	0.01	0.63	FALSE
26	The Cancer Genome Atlas	Thyroid Carcinoma	ARFRP1	0.04	0.00	blup	51	0.00	1.3e-01	-6.47	6.0	2.5e-09	-0.81	0.01	0.60	FALSE
27	The Cancer Genome Atlas	Thyroid Carcinoma	LIME1	0.05	0.03	blup	47	0.04	3.9e-05	-6.01	-5.9	3.3e-09	0.81	0.04	0.94	FALSE