[Hub]/) : Traits : Crohns Disease (2017) : ← →

chr2:233,227,833-235,170,697

Best TWAS P=5.36e-61 · Best GWAS P=1.77e-62 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Brain Cerebellum	ATG16L1	0.23	0.27	lasso	4	0.30	2.0e-09	-16.47	-16.5	5.4e-61	0.98	0.02	0.98	TRUE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SCARNA5	0.03	0.01	blup	55	0.02	2.4e-03	-8.48	6.8	1.4e-11	-0.62	0.07	0.18	TRUE
10	GTEx	Skin Not Sun Exposed Suprapubic	ATG16L1	0.12	0.10	enet	11	0.11	1.7e-06	-16.56	16.1	4.5e-58	-0.98	0.02	0.98	FALSE
2	GTEx	Adipose Subcutaneous	ATG16L1	0.14	0.11	lasso	4	0.10	6.4e-09	-15.87	-15.8	5.2e-56	0.96	0.03	0.97	FALSE
7	GTEx	Esophagus Muscularis	ATG16L1	0.11	0.03	lasso	6	0.02	2.7e-02	-14.12	-15.7	2.4e-55	0.95	0.02	0.96	FALSE
6	GTEx	Esophagus Mucosa	ATG16L1	0.11	0.02	enet	10	0.00	2.3e-01	-16.68	15.2	4.2e-52	-0.88	0.02	0.91	FALSE
20	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ATG16L1	0.11	0.05	blup	81	0.09	1.9e-04	-15.85	-14.8	7.3e-50	0.91	0.02	0.84	FALSE
12	GTEx	Testis	ATG16L1	0.34	0.19	enet	29	0.23	1.4e-10	-16.52	14.4	8.1e-47	-0.86	0.02	0.98	FALSE
17	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ATG16L1	0.05	0.04	enet	12	0.05	5.4e-06	-12.51	14.0	8.2e-45	-0.81	0.02	0.98	FALSE
8	GTEx	Nerve Tibial	ATG16L1	0.24	0.18	enet	21	0.19	3.5e-13	-15.87	-13.9	5.4e-44	0.90	0.05	0.95	FALSE
11	GTEx	Skin Sun Exposed Lower leg	ATG16L1	0.21	0.08	enet	18	0.10	5.6e-09	-16.46	13.7	1.1e-42	-0.90	0.02	0.98	FALSE
22	The Cancer Genome Atlas	Thyroid Carcinoma	SCARNA5	0.04	0.00	blup	55	0.02	8.2e-03	-14.12	-13.2	7.2e-40	0.74	0.02	0.46	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	ATG16L1	0.22	0.06	enet	36	0.10	6.2e-12	-15.87	-12.1	1.2e-33	0.69	0.03	0.97	FALSE
3	GTEx	Brain Caudate basal ganglia	ATG16L1	0.21	0.09	lasso	2	0.10	6.8e-04	-11.97	-11.4	5.5e-30	0.75	0.10	0.56	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ATG16L1	0.06	0.03	bslmm	587	0.03	3.3e-04	-4.38	10.7	8.5e-27	-0.61	0.06	0.90	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	ATG16L1	0.28	0.26	lasso	9	0.28	3.3e-36	-7.05	-10.6	2.0e-26	0.78	1.00	0.00	FALSE
16	YFS	Blood	ATG16L1	0.21	0.28	lasso	7	0.30	2.2e-99	-6.95	9.6	5.7e-22	-0.72	1.00	0.00	FALSE
9	GTEx	Pituitary	ATG16L1	0.36	0.16	lasso	8	0.19	1.3e-05	-9.63	-9.3	1.8e-20	0.71	0.06	0.86	FALSE
21	The Cancer Genome Atlas	Stomach Adenocarcinoma	ATG16L1	0.07	0.04	lasso	4	0.03	3.6e-03	-9.31	9.3	1.8e-20	-0.72	0.03	0.18	FALSE
14	METSIM	Adipose	INPP5D	0.05	0.01	lasso	4	0.03	6.2e-06	1.14	-8.9	4.7e-19	0.56	0.02	0.97	FALSE
5	GTEx	Cells Transformed fibroblasts	USP40	0.30	0.09	enet	14	0.14	7.7e-11	3.77	5.7	1.4e-08	-0.43	1.00	0.00	FALSE
13	METSIM	Adipose	DGKD	0.06	0.02	bslmm	713	0.02	4.2e-04	-0.57	5.1	3.1e-07	-0.27	0.75	0.04	FALSE