TWAS hub - SCARNA5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Kidney Renal Clear Cell Carcinoma	0.033	0.020	0.0043	0.012	0.020	0.007	NA	0.017	0.014	0.0024	0.047	NA	0.0047
2	TCGA	Thyroid Carcinoma	0.044	0.031	0.0089	0.003	0.017	0.011	NA	0.008	0.170	0.0082	0.025	NA	0.0520

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Crohns Disease (2017)	50.1	110.0	174.2	6.8	-13.2
Crohns Disease (2012)	44.5	71.7	99.4	6.6	-10.0
Irritable Bowel Disease (IBD)	19.7	46.8	71.7	4.7	-8.5
Eye problems/disorders: None of the above	8.4	9.7	17.4	1.4	-4.2
Glaucoma (self-reported)	8.2	9.6	12.8	-2.5	3.6
Eye problems/disorders: Glaucoma	6.7	8.0	11.4	-2.1	3.4
Breastfed as a baby	5.0	6.2	8.8	3.0	-1.9
Type 2 Diabetes (T2D) (2018)	4.0	7.4	12.9	-1.4	3.6
Medication: Metformin	3.9	5.4	9.6	-1.1	3.1
Illnesses of siblings	3.6	5.1	7.0	-1.8	2.6
Medication: Ibuprofen	3.6	4.4	8.7	3.0	-0.1
Ever used hormone-replacement therapy (HRT)	3.4	4.3	5.2	-1.8	2.3
Medication: Bendroflumethiazide	3.2	4.9	9.3	0.7	-3.0
Primary Biliary Cirrhosis	3.1	4.4	7.7	2.8	-1.1
Number of children fathered	3.1	3.5	5.9	-1.1	2.4
Tinnitus: Yes, now most or all of the time	3.1	3.7	7.0	-2.6	-0.5
Medication: Ibuprofen (e.g. Nurofen)	2.8	3.6	7.1	2.7	0.3
Ever had bowel cancer screening	2.7	3.1	3.6	-1.9	1.6
Ever taken oral contraceptive pill	2.7	3.0	3.2	1.7	-1.8
Alzheimer’s Disease (in mother)	2.6	3.0	4.6	-2.1	-1.2
Severe depression (siblings)	2.6	2.9	3.1	1.6	-1.8
Eye problems/disorders: Diabetes related eye disease	2.5	2.7	4.3	-1.1	2.1
Heart attack	2.5	3.2	3.8	1.9	-1.6
Medication: Paracetamol	2.5	3.8	4.0	2.0	-1.9
Tense / ‘highly strung’	2.4	3.9	4.0	2.0	-2.0
Schizophrenia vs Biploar Disorder	2.3	3.0	3.7	1.9	-1.6
Reaction Time	2.3	4.3	7.9	2.8	-0.9
Medication: Co-codamol	2.3	2.6	5.2	2.3	-0.3
Noisy workplace	2.3	2.8	5.5	-2.3	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.3	2.8	4.3	2.1	-1.1
Medication: Lisinopril	2.3	3.0	5.3	0.9	-2.3
Supplements: Zinc	2.2	2.4	4.7	0.3	-2.2
HbA1C	2.1	2.3	4.4	0.5	2.1
Allergy or Eczema	2.1	5.5	6.0	2.2	-2.5
Hayfever, allergic rhinitis or eczema	2.1	4.6	5.4	2.3	-2.0
Lung cancer (father)	2.1	2.5	4.2	-2.0	-0.9
Ulcerative Colitis	2.0	2.9	3.8	1.4	-2.0
Diverticular disease/diverticulitis (self-reported)	2.0	2.4	4.5	0.4	-2.1
Number of incorrect matches in round	2.0	3.3	5.8	2.4	-1.0
Length of working week for main job	2.0	2.2	3.3	1.8	-1.1
Mean time to correctly identify matches	2.0	3.7	5.2	2.3	-1.5
Cardiovascular Disease	1.8	5.9	9.1	1.6	-3.0
Angina	1.8	2.3	4.5	0.3	-2.1
Relative age voice broke	1.8	2.7	3.1	1.5	-1.8
Diabetes (self-reported)	1.8	2.8	5.5	-0.2	2.3
Ever had prostate specific antigen (PSA) test	1.8	2.1	4.1	-2.0	0.3
Vascular/heart problems diagnosed by doctor	1.8	5.0	8.1	-1.4	2.8
Hearing difficulty/problems with background noise	1.7	2.6	4.5	2.1	-0.9
Exposure to tobacco smoke at home	1.7	1.9	3.8	-0.2	1.9
Illnesses of father: Heart disease	1.7	2.3	3.0	-1.3	-1.7
Diabetes diagnosed by doctor	1.7	2.8	5.5	-0.4	2.3
Hair/balding pattern: Pattern 2	1.6	2.1	3.4	-1.8	0.9
Asthma	1.6	3.2	3.8	1.6	-2.0
Medication for cholesterol, blood pressure or diabetes	1.6	2.6	4.2	-1.0	2.1
High blood pressure (siblings)	1.6	2.4	3.6	1.1	-1.9
Medication: Blood pressure	1.6	2.9	3.9	1.4	-2.0
Hair/balding pattern: Pattern 3	1.5	2.3	4.5	-0.3	-2.1
Medication: Paracetamol	1.5	2.5	3.1	1.8	-1.4
Medication for pain relief, constipation, heartburn	1.5	2.5	4.9	-2.2	0.2
Angina (self-reported)	1.5	2.0	4.0	-0.0	-2.0
Asthma (self-reported)	1.5	3.0	4.0	1.4	-2.0
Financial situation satisfaction	1.5	1.9	2.4	1.6	-1.2
Heart attack/myocardial infarction (self-reported)	1.5	1.9	2.3	1.5	-1.2
Medication for hormone replacement therapy	1.4	1.5	2.3	-0.9	1.5
High blood pressure	1.4	3.9	5.9	1.3	-2.4
Relative age of first facial hair	1.3	2.6	3.8	2.0	-1.2
Had menopause	1.3	1.6	1.8	-1.4	1.1
Allergy	1.3	3.1	3.5	-1.9	1.6
Breast cancer (self-reported)	1.3	1.6	1.7	-1.2	1.3
Medication: Blood pressure	1.2	2.2	4.4	0.3	-2.1
Heart disease (siblings)	1.2	1.5	2.9	-0.3	-1.7
Bipolar Disorder (2018)	1.1	1.8	3.0	-1.7	0.8
Coronary Artery Disease (CAD)	1.1	1.4	2.7	0.0	-1.6
HDL Cholesterol	1.1	1.9	3.0	-0.9	-1.7
Blood Platelet Count	1.1	12.8	23.4	-1.5	4.8
Nervous feelings	1.1	2.1	2.1	1.4	-1.4
Financial difficulties in last 2 years	1.1	1.4	1.9	1.4	-1.0
Pain all over the body in last month	1.1	1.1	1.9	-1.4	0.6
Impedance of arm (right)	1.1	5.1	6.9	1.8	-2.6
Birth weight of first child	1.1	1.9	3.5	-1.9	-0.6
Hypertension (Self-reported)	1.1	3.0	4.8	1.1	-2.2
Supplements: Fish oil (including cod liver oil)	1.1	1.4	2.3	-1.5	-0.7
Average weekly beer plus cider intake	1.1	1.6	3.0	-0.6	-1.7
Commuting to job workplace: Cycle	1.1	1.4	2.0	0.9	-1.4
Worry (Nagel 2018)	1.0	2.1	2.7	1.2	-1.6
Breast Cancer	1.0	2.3	2.6	1.6	-1.4
Diabetes (mother)	1.0	1.3	2.5	1.6	-0.2
Chest pain or discomfort	1.0	1.4	2.6	0.4	-1.6
Commuting to job workplace: Car/motor vehicle	1.0	1.1	2.2	-1.5	-0.1
Knee pain experienced in last month	1.0	1.5	1.8	-1.4	1.1
Leg fat-free mass (right)	1.0	5.3	6.7	-2.0	2.6
Qualifications: nursing, teaching	1.0	1.5	2.4	-0.8	1.5
Leg predicted mass (right)	1.0	5.2	6.5	-1.9	2.5
Medication: Atorvastatin	1.0	1.2	1.6	0.9	-1.3
Major Depression (MDD)	0.9	1.0	1.3	-0.9	-1.2
Impedance of leg (right)	0.9	4.6	5.1	2.0	-2.2
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	1.4	1.2	-0.7
Alcohol intake versus 10 years previously	0.9	1.4	2.8	1.7	0.1
Pulse wave Arterial Stiffness index	0.9	1.0	2.1	-0.1	-1.4
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	2.1	-1.5	0.9
Arm fat-free mass (right)	0.9	4.6	5.8	-1.8	2.4
Worry too long after embarrassment	0.9	1.5	3.0	-0.0	-1.7
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	2.2	1.5	-0.2
Age at last live birth	0.9	1.3	2.4	1.5	-0.5
Ever smoked	0.9	1.6	1.9	1.4	1.1
Leg fat-free mass (left)	0.8	4.3	6.0	-1.6	2.4
Leg predicted mass (left)	0.8	4.5	6.2	-1.6	2.5
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	1.5	0.9	-1.2
Falls in the last year	0.8	1.1	2.1	-0.1	-1.5
Happiness	0.8	1.0	1.2	1.1	-0.9
Mouth/teeth dental problems: Dentures	0.8	1.3	2.4	1.6	0.4
Pulse wave reflection index	0.8	1.0	1.0	0.9	-1.0
Pulse wave peak to peak time	0.8	0.9	1.8	0.1	1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	1.7	-1.3	0.3
Friendships satisfaction	0.8	1.0	1.2	1.1	0.9
Average weekly champagne plus white wine intake	0.8	1.1	1.3	-1.2	0.9
Wears glasses or contact lenses	0.8	1.0	1.6	-1.3	-0.6
Alcohol drinker status: Never	0.8	1.0	1.5	-0.7	-1.2
Number of operations (self-reported)	0.8	1.2	1.8	0.8	1.3
Waist Hip Ratio (WHR)	0.7	2.9	3.8	2.0	-1.4
Average weekly fortified wine intake	0.7	0.8	1.1	0.8	-1.1
Medication: Ramipril	0.7	0.9	0.9	-0.9	-0.9
Worrier / anxious feelings	0.7	1.4	2.8	1.7	-0.1
Birth weight	0.7	1.5	1.9	-1.0	1.4
Number of full brothers	0.7	0.9	1.7	-0.2	1.3
Family relationship satisfaction	0.7	0.9	1.0	1.0	-0.9
Supplements: Vitamin C	0.7	0.8	1.1	-1.0	-0.7
Average weekly red wine intake	0.7	1.1	2.1	-0.3	1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	1.1	1.1	-0.6
Medication: Aspirin	0.7	0.9	1.0	1.0	0.9
Number of self-reported non-cancer illnesses	0.7	1.2	2.3	0.2	-1.5
Hearing aid user	0.7	0.8	1.5	-1.2	-0.0
Alzheimer’s Disease (including proxy)	0.6	0.9	1.1	-1.1	-0.8
Fasting Glucose	0.6	0.7	1.5	-1.2	-0.1
Lung FEV1/FVC ratio	0.6	2.9	3.2	1.6	-1.8
Number of treatments/medications taken	0.6	1.1	1.7	0.7	-1.3
Serious illness, injury or assault to yourself	0.6	0.7	0.9	-0.9	0.7
High blood pressure (mother)	0.6	0.8	1.2	-0.6	-1.1
Impedance of leg (left)	0.6	3.1	4.2	1.4	-2.1
Fluid intelligence score	0.6	1.2	1.8	0.7	1.4
Number of live births	0.6	0.8	1.7	-0.1	1.3
Gout (self-reported)	0.6	0.9	1.7	0.3	-1.3
Emphysema/chronic bronchitis	0.6	0.6	1.2	-1.1	-0.1
Arm predicted mass (right)	0.6	3.2	3.8	-1.6	1.9
Comparative height size at age 10	0.6	3.6	4.1	-1.8	2.0
Medication: Aspirin	0.6	0.8	1.0	0.8	1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	2.3	0.6	-1.5
Whole body fat-free mass	0.6	3.3	4.5	-1.4	2.1
Handedness (chirality/laterality): Left-handed	0.6	0.7	0.8	0.8	0.9
Osteoarthritis (self-reported)	0.6	0.8	1.0	-1.0	0.8
Smoking status: Current	0.6	0.9	1.3	-0.7	1.2
Whole body water mass	0.6	3.4	4.5	-1.5	2.1
Basal metabolic rate	0.6	3.1	4.2	-1.4	2.0
Depression (Nagel 2018)	0.5	0.7	1.2	1.1	-0.5
Neuroticism (Nagel 2018)	0.5	1.1	2.0	0.4	-1.4
Verbal and Numeric Reasoning (VNR)	0.5	1.1	2.3	0.0	1.5
Ovarian Cancer	0.5	0.7	1.2	0.3	-1.1
Systolic Blood Pressure	0.5	2.4	3.7	-1.0	-1.9
Townsend deprivation index at recruitment	0.5	0.7	1.3	1.2	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	0.9	-0.6	1.0
Chronic bronchitis/emphysema (father)	0.5	0.6	1.1	1.1	-0.4
Forced vital capacity (FVC)	0.5	1.8	3.4	-0.3	1.8
Medication: Simvastatin	0.5	0.7	1.4	-0.2	1.2
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.0	-0.5	1.0
Headache pain in last month	0.5	0.8	1.3	-0.5	-1.1
Shortness of breath walking on level ground	0.5	0.6	1.1	-0.3	1.1
Mother’s age at death	0.5	0.7	1.3	1.1	-0.3
Illnesses of father: High blood pressure	0.5	0.6	1.3	0.1	-1.1
Ever depressed for a whole week	0.5	0.6	1.1	-1.0	0.2
Impedance of whole body	0.5	2.6	3.7	1.2	-1.9
Intelligence (Savage-Jansen 2018)	0.4	1.1	1.1	1.1	1.1
Smoking Status	0.4	0.9	1.3	-0.8	1.1
Neuroticism	0.4	1.0	1.3	0.8	-1.1
Hearing difficulty/problems: Yes	0.4	0.7	1.1	1.0	0.5
Vitamin and mineral supplements	0.4	0.5	0.8	0.5	0.9
Current tobacco smoking	0.4	0.6	1.1	-0.3	1.0
Fed-up feelings	0.4	0.7	0.8	-0.9	-0.8
Age when periods started (menarche)	0.4	1.0	1.5	0.7	-1.2
Qualifications: CSEs or equivalent	0.4	0.5	0.9	0.9	-0.4
Stomach or abdominal pain in last month	0.4	0.5	0.7	-0.8	0.5
Supplements: Glucosamine	0.4	0.6	1.1	-1.0	-0.3
Medication: Levothyroxine sodium	0.4	0.7	0.7	0.8	0.8
Weight	0.4	1.9	2.4	-1.2	1.6
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	2.1	-0.7	1.4
Prospective memory result	0.4	0.4	0.8	-0.3	-0.9
Impedance of arm (left)	0.4	1.6	2.8	0.7	-1.7
Blood clot in the leg (DVT)	0.4	0.5	0.5	-0.7	0.6
Medication: Ventolin 100micrograms inhaler	0.4	0.5	0.8	0.5	-0.9
Chronic bronchitis/emphysema (mother)	0.4	0.4	0.8	0.9	0.2
Forced vital capacity (FVC), Best measure	0.4	1.5	1.9	-1.1	1.4
Wheeze or whistling in the chest in last year	0.4	0.7	0.8	0.7	0.9
Mouth/teeth dental problems: Loose teeth	0.4	0.4	0.6	-0.5	0.8
Medication: Seretide 50 evohaler	0.4	0.5	0.6	-0.8	0.7
Alcohol intake frequency.	0.4	1.0	1.7	0.6	-1.3
Suffer from ‘nerves’	0.4	0.6	1.2	-0.2	-1.1
Loneliness, isolation	0.4	0.6	0.6	-0.8	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.1	1.1	-0.1
Medication for cholesterol	0.4	0.6	1.2	0.2	1.1
Mineral and other dietary supplements	0.4	0.6	0.9	1.0	0.5
Medication: Gliclazide	0.4	0.4	0.6	0.4	0.8
Guilty feelings	0.4	0.6	0.8	0.9	-0.7
Arm fat-free mass (left)	0.4	2.0	2.3	-1.3	1.5
Irritability	0.4	0.6	1.0	1.0	-0.5
Fractured/broken bones in last 5 years	0.4	0.5	0.9	-1.0	-0.3
Myopia	0.4	0.6	0.7	0.9	0.7
Supplements: Calcium	0.4	0.5	0.6	-0.8	-0.6
Bipolar Disorder or Schizophrenia	0.3	0.7	1.4	-1.2	0.1
Alzheimer’s Disease (in father)	0.3	0.3	0.5	0.4	-0.7
Prostate Cancer	0.3	0.4	0.7	0.8	-0.0
Age at First Birth	0.3	0.5	0.5	0.6	0.7
Body Mass Index (BMI) (2010)	0.3	0.5	0.6	-0.6	-0.8
Height	0.3	5.8	11.4	-0.3	3.4
Chronotype (morning person)	0.3	0.6	0.9	-1.0	0.6
Frequency of depressed mood in last 2 weeks	0.3	0.4	0.6	0.4	-0.8
Ever had hysterectomy (womb removed)	0.3	0.3	0.3	0.6	-0.5
Diabetes (father)	0.3	0.4	0.7	-0.8	0.1
Multivitamins +/- minerals	0.3	0.3	0.5	0.4	-0.7
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	0.7	0.1	-0.8
Mouth/teeth dental problems	0.3	0.4	0.6	-0.7	-0.6
Neuroticism score	0.3	0.6	0.9	0.5	-1.0
Trunk fat-free mass	0.3	1.8	2.6	-1.1	1.6
Father’s age at death	0.3	0.4	0.6	0.3	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	0.7	-0.8	0.6
Pulse rate	0.3	0.5	0.7	0.9	-0.5
Depression (self-reported)	0.3	0.4	0.5	0.6	0.7
Illnesses of mother	0.3	0.4	0.6	0.4	0.8
Trunk predicted mass	0.3	2.0	2.8	-1.1	1.7
Medication: Amlodipine	0.3	0.4	0.4	0.6	0.6
Exposure to tobacco smoke outside home	0.3	0.4	0.5	0.7	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	0.6	0.8	-0.3
Pulse rate, automated reading	0.3	0.9	1.5	0.5	1.2
Had major operations	0.3	0.4	0.4	0.6	0.6
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	0.6	0.8	-0.4
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.7	-0.3	-0.8
Eye problems/disorders: Cataract	0.3	0.3	0.6	0.0	0.8
Back pain experienced in last month	0.3	0.5	0.8	0.9	-0.4
Illnesses of father: None of the above (group 1)	0.3	0.4	0.8	-0.1	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	0.8	0.6	-0.9
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	0.5	-0.6	0.7
Alcohol drinker status: Previous	0.3	0.3	0.6	-0.1	-0.8
Arm predicted mass (left)	0.3	1.4	2.1	-0.8	1.5
Depressed Affect (Nagel 2018)	0.2	0.3	0.6	-0.8	-0.3
Ulcerative Colitis (UC)	0.2	0.4	0.6	0.8	-0.4
Bipolar Disorder (2011)	0.2	0.1	0.2	-0.2	0.5
Lupus	0.2	0.2	0.5	-0.7	-0.0
Blood Eosinophil Count	0.2	1.4	2.7	-1.6	0.1
Blood Red Count	0.2	1.9	2.0	-1.4	-1.3
Respiratory disease	0.2	0.4	0.4	-0.7	-0.6
Systolic blood pressure, automated reading	0.2	0.6	0.8	-0.9	-0.6
Taking other prescription medications	0.2	0.3	0.5	-0.7	0.0
Sitting height	0.2	1.1	1.7	-1.3	0.7
Body mass index (BMI)	0.2	0.7	1.0	-0.7	1.0
Past tobacco smoking	0.2	0.4	0.7	-0.1	-0.9
Alcohol usually taken with meals	0.2	0.3	0.6	-0.8	0.1
Had other major operations	0.2	0.2	0.4	0.7	0.2
Hip circumference	0.2	0.8	1.0	-0.9	1.0
Time employed in main current job	0.2	0.2	0.4	0.6	0.3
Medication: Lansoprazole	0.2	0.2	0.4	-0.0	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.5	0.7	-0.9	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.2	0.5	-0.1	0.7
Loud music exposure frequency	0.2	0.2	0.3	0.3	0.6
Qualifications: College or University degree	0.2	0.7	1.3	1.2	-0.1
Neck or shoulder pain in last month	0.2	0.4	0.7	0.8	-0.0
Migraine (self-reported)	0.2	0.3	0.4	-0.6	-0.5
Medication: Allopurinol	0.2	0.3	0.5	0.2	-0.7
Medication: Omeprazole	0.2	0.2	0.3	0.4	0.5
Leg pain on walking	0.2	0.3	0.5	-0.3	0.7
Osteoporosis (self-reported)	0.2	0.2	0.4	-0.1	-0.6
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.4	-0.4	0.6
Cholesterol lowering medication	0.2	0.2	0.4	-0.7	0.0
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.4	-0.2	0.6
Basal cell carcinoma (self-reported)	0.2	0.2	0.4	0.3	-0.6
Leg fat mass (left)	0.2	0.9	1.1	-0.9	1.0
Schizophrenia (2018)	0.1	0.1	0.2	-0.4	-0.2
Mean Putamen Volume	0.1	0.1	0.1	0.3	0.1
Rheumatoid Arthritis	0.1	0.2	0.3	-0.6	-0.3
Triglycerides	0.1	0.1	0.2	0.5	0.0
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.2	0.4	0.3
Blood White Count	0.1	0.8	1.7	-0.1	1.3
Hair Pigment	0.1	3.0	5.9	-0.3	-2.4
Hand grip strength (left)	0.1	0.3	0.6	-0.2	0.7
Average weekly spirits intake	0.1	0.2	0.3	0.6	0.2
Sensitivity / hurt feelings	0.1	0.1	0.2	-0.2	-0.4
Hand grip strength (right)	0.1	0.2	0.4	0.6	0.3
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.2	0.4	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.3	-0.6	0.5
Trunk fat mass	0.1	0.3	0.4	-0.4	0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.3	0.6	0.0
Qualifications: None of the above	0.1	0.2	0.3	-0.5	0.4
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.4	0.6	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.2	-0.3	0.4
Arm fat mass (right)	0.1	0.3	0.4	-0.6	0.6
Standing height	0.1	1.4	1.7	-1.0	1.3
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.3	0.0	0.5
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	0.4	0.3	0.7
Health satisfaction	0.1	0.1	0.1	-0.0	-0.4
Heart disease (mother)	0.1	0.2	0.2	0.5	-0.4
Whole body fat mass	0.1	0.6	0.7	-0.7	0.8
Leg fat mass (right)	0.1	0.5	0.6	-0.5	0.8
Number of full sisters	0.1	0.1	0.1	-0.2	0.4
Illnesses of siblings: Diabetes	0.1	0.1	0.3	0.5	0.1
Arm fat percentage (left)	0.1	0.3	0.6	-0.8	0.3
Commuting to job workplace: Walk	0.1	0.1	0.1	-0.3	0.0
Arm fat mass (left)	0.1	0.6	0.7	-0.8	0.7
Miserableness	0.1	0.1	0.2	-0.5	-0.2
Risk taking	0.1	0.1	0.2	0.2	-0.4
Age started oral contraceptive pill	0.1	0.2	0.3	-0.5	-0.2
Unable to work because of sickness or disability	0.1	0.2	0.3	-0.3	0.5
Pain experienced in last month	0.1	0.2	0.4	0.6	0.1
LDL Cholesterol	0.0	0.0	0.1	0.2	-0.1
Neuroticism (2016)	0.0	0.1	0.1	-0.1	0.3
Schizophrenia (2014)	0.0	0.1	0.2	0.1	0.4
Heel T-Score	0.0	0.4	0.7	0.2	0.8
BMI	0.0	0.1	0.1	-0.4	0.3
Hypothyroidism (self reported)	0.0	0.0	0.1	0.0	0.2
Lung FVC	0.0	0.0	0.0	0.0	-0.1
Tanning	0.0	0.2	0.4	-0.1	0.6
Other serious medical condition/disability diagnosed by doctor	0.0	0.0	0.0	-0.1	0.1
Pack years adult smoking proportion	0.0	0.0	0.0	-0.2	0.1
Trunk fat percentage	0.0	0.0	0.0	-0.0	-0.1
Maternal smoking around birth	0.0	0.0	0.0	0.2	0.1
Medication: Atenolol	0.0	0.1	0.1	-0.2	-0.3
Waist circumference	0.0	0.2	0.3	0.3	0.5
Hayfever/allergic rhinitis (self-reported)	0.0	0.0	0.1	0.3	-0.1
Arm fat percentage (right)	0.0	0.0	0.1	-0.2	-0.2
Medication: Cholesterol lowering	0.0	0.1	0.1	0.3	-0.2
Hair/balding pattern: Pattern 4	0.0	0.0	0.1	0.2	-0.1
Peak expiratory flow (PEF)	0.0	0.1	0.1	-0.2	0.2
Body fat percentage	0.0	0.0	0.1	-0.3	0.0
Leg fat percentage (right)	0.0	0.0	0.0	0.2	-0.1
Comparative body size at age 10	0.0	0.1	0.1	-0.2	0.3
Age at first live birth	0.0	0.0	0.0	0.0	-0.2
Overall health rating	0.0	0.1	0.2	-0.4	0.2
Smoking status: Previous	0.0	0.0	0.0	0.1	-0.1
Mood swings	0.0	0.0	0.1	-0.2	0.1
Long-standing illness, disability or infirmity	0.0	0.0	0.0	0.2	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.0	0.0	0.1	0.1
Commuting to job workplace: Public transport	0.0	0.0	0.0	0.1	0.1
High cholesterol (Self-reported)	0.0	0.0	0.0	0.1	-0.2
Leg fat percentage (left)	0.0	0.1	0.1	-0.3	0.3
Diastolic blood pressure, automated reading	0.0	0.1	0.2	-0.5	0.1
Pack years of smoking	0.0	0.0	0.0	-0.2	0.1

Hub : Genes

SCARNA5

Models

Trait associations