Hub : Genes

ATG16L1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.065	0.0250	8.3e-04	0.026	0.021	0.004	0.026	0.022	3.7e-04	1.1e-03	8.5e-02	3.3e-04	9.4e-04
2	GTEx	Adipose Subcutaneous	0.140	0.0390	3.0e-06	0.108	NA	0.101	NA	0.105	3.6e-09	NA	1.4e-08	NA	6.4e-09
3	GTEx	Brain Caudate basal ganglia	0.209	0.0820	5.4e-03	0.086	NA	0.062	NA	0.103	1.8e-03	NA	7.2e-03	NA	6.8e-04
4	GTEx	Brain Cerebellum	0.233	0.0770	7.9e-04	0.267	NA	0.150	NA	0.297	1.6e-08	NA	3.4e-05	NA	2.0e-09
5	GTEx	Esophagus Mucosa	0.110	0.0500	6.8e-03	0.015	NA	0.002	NA	0.002	3.1e-02	NA	2.3e-01	NA	2.3e-01
6	GTEx	Esophagus Muscularis	0.106	0.0420	5.4e-03	0.031	NA	0.011	NA	0.018	5.4e-03	NA	7.1e-02	NA	2.7e-02
7	GTEx	Nerve Tibial	0.236	0.0524	2.7e-09	0.185	NA	0.186	NA	0.162	4.3e-13	NA	3.5e-13	NA	1.4e-11
8	GTEx	Pituitary	0.362	0.1090	2.1e-04	0.161	NA	0.139	NA	0.194	7.8e-05	NA	2.4e-04	NA	1.3e-05
9	GTEx	Skin Not Sun Exposed Suprapubic	0.124	0.0480	2.0e-03	0.098	NA	0.108	NA	0.031	4.9e-06	NA	1.7e-06	NA	8.2e-03
10	GTEx	Skin Sun Exposed Lower leg	0.208	0.0480	6.3e-08	0.078	NA	0.105	NA	0.104	5.4e-07	NA	5.6e-09	NA	6.0e-09
11	GTEx	Testis	0.340	0.0760	1.7e-06	0.190	NA	0.230	NA	0.121	7.6e-09	NA	1.5e-10	NA	5.0e-06
12	ROSMAP	Brain Pre-frontal Cortex	0.280	0.0449	0.0e+00	0.258	0.237	0.261	0.276	0.281	4.6e-33	4.7e-30	1.8e-33	1.3e-35	3.3e-36
13	YFS	Blood	0.212	0.0269	0.0e+00	0.280	0.272	0.298	0.291	0.298	3.4e-92	2.4e-89	4.9e-99	2.4e-96	2.2e-99
14	TCGA	Head and Neck Squamous Cell Carcinoma	0.052	0.0253	5.5e-05	0.045	0.027	0.047	NA	0.046	8.0e-06	4.3e-04	5.4e-06	NA	6.1e-06
15	TCGA	Brain Lower Grade Glioma	0.217	0.0606	1.4e-10	0.057	0.101	0.105	NA	0.037	4.8e-07	1.6e-11	6.2e-12	NA	4.8e-05
16	TCGA	Pheochromocytoma and Paraganglioma	0.114	0.0630	2.5e-03	0.047	0.090	0.068	NA	0.042	6.1e-03	1.9e-04	1.2e-03	NA	9.1e-03
17	TCGA	Stomach Adenocarcinoma	0.072	0.0430	7.5e-03	0.037	0.022	0.013	NA	0.029	9.8e-04	9.6e-03	3.6e-02	NA	3.6e-03
18	TCGA	Testicular Germ Cell Tumors	0.463	0.1210	5.7e-03	0.066	0.038	0.126	NA	0.143	2.3e-03	1.8e-02	3.4e-05	NA	9.4e-06

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Bipolar Disorder (2018)	0.5	0.8	2.2	-0.6	0.8	1.1	0.8	-0.1	0.8	0.9	1.3	-0.8	-0.3	-0.7	1.1	-1.2	-0.9	0.5	1.2	-1.5	-0.1
Bipolar Disorder or Schizophrenia	0.3	0.7	2.5	0.1	0.6	1.4	0.2	0.5	0.5	0.8	0.7	-0.3	-0.6	0.3	1.5	-1.6	-0.7	0.7	0.4	-1.2	-0.0
Depressed Affect (Nagel 2018)	0.5	1.0	5.8	2.1	-0.3	-0.6	-0.6	1.5	-0.0	0.0	-0.7	0.4	0.2	0.7	0.3	-0.8	-0.4	1.1	-0.6	0.4	2.4
Depression (Nagel 2018)	1.8	2.7	6.2	2.4	-1.4	-1.6	-1.9	2.5	-1.5	-0.9	-1.2	1.8	2.2	2.5	-0.6	0.4	1.6	0.1	-1.4	2.3	0.0
Intelligence (Savage-Jansen 2018)	0.3	0.8	5.6	0.1	-0.5	0.4	-0.2	-0.2	-0.4	-0.8	-0.9	0.4	0.1	0.9	-0.8	1.4	0.7	-1.0	0.2	1.3	-2.4
Neuroticism (Nagel 2018)	0.7	1.6	4.8	2.2	-1.2	-1.1	-1.4	2.0	-1.0	-0.9	-1.5	1.4	1.1	1.2	-0.6	0.2	0.0	0.4	-1.2	1.4	1.8
Schizophrenia (2018)	0.2	0.4	1.2	0.6	0.2	0.9	-0.3	0.7	-0.1	0.2	-0.1	0.2	-0.6	1.0	1.1	-1.0	-0.1	0.6	-0.0	-0.3	-1.1
Schizophrenia vs Biploar Disorder	2.1	2.7	5.9	0.9	-2.0	-1.6	-1.7	0.9	-1.8	-2.1	-2.4	1.8	1.8	1.1	-2.2	2.4	1.0	-0.9	-1.7	1.2	0.0
Worry (Nagel 2018)	1.5	3.2	7.6	2.2	-2.0	-1.7	-1.9	2.5	-1.4	-1.8	-2.8	2.0	1.7	1.7	-1.6	1.3	0.2	0.2	-1.6	2.1	1.2
Alzheimer’s Disease (in mother)	1.0	1.2	4.9	1.7	-0.9	0.4	-1.0	1.3	-0.6	-0.0	0.9	0.7	0.2	1.2	0.7	-0.8	1.2	-2.2	-0.5	-1.0	1.6
Alzheimer’s Disease (in father)	1.4	1.6	5.0	1.3	-1.4	-1.2	-1.3	1.2	-1.1	-1.2	-1.1	1.3	1.1	1.3	-1.1	1.1	2.2	-1.2	-0.9	1.0	0.8
Alzheimer’s Disease (including proxy)	2.0	2.9	9.8	2.9	-1.5	-0.1	-1.7	2.2	-1.2	-0.8	0.0	1.4	0.7	2.4	-0.0	-0.0	2.7	-3.1	-0.9	0.7	2.3
Crohns Disease (2017)	77.2	169.4	272.2	10.7	-15.8	-11.4	-16.5	15.2	-15.7	-13.9	-9.3	16.1	13.7	14.4	-10.6	9.6	14.0	-12.1	-14.8	9.3	-4.5
Irritable Bowel Disease (IBD)	33.0	78.5	121.0	7.4	-10.6	-8.1	-11.0	10.3	-10.4	-9.5	-7.2	10.8	9.0	9.7	-7.3	6.6	10.0	-7.7	-9.8	6.7	-3.8
Ulcerative Colitis (UC)	1.4	2.6	5.7	1.5	-1.4	-1.8	-1.6	1.7	-1.3	-1.5	-2.3	1.6	1.0	1.9	-1.1	1.0	2.4	-0.6	-1.0	1.7	-2.2
Major Depression (MDD)	0.2	0.3	3.1	-0.1	0.1	-0.1	0.1	-0.3	0.0	0.3	0.1	-0.3	-0.6	-0.6	0.2	-0.6	0.0	0.0	0.2	-1.8	0.0
Reaction Time	2.1	4.0	9.6	0.5	-2.0	-1.9	-1.9	2.0	-1.6	-2.0	-3.1	2.1	2.8	1.7	-2.3	2.1	1.9	-0.5	-2.4	2.3	0.8
Verbal and Numeric Reasoning (VNR)	0.5	1.2	3.0	-1.1	1.2	1.6	1.5	-1.7	1.0	0.7	0.5	-1.2	-1.4	-0.5	0.6	0.1	-0.7	-0.4	1.7	-0.1	-1.1
Breast Cancer	2.4	5.7	10.2	1.7	-2.6	-2.2	-2.9	2.5	-2.9	-2.6	-1.9	2.9	3.0	1.9	-2.3	2.1	3.2	-1.0	-2.2	2.2	-1.2
Ovarian Cancer	0.8	1.0	3.8	1.7	-0.9	-0.2	-1.2	1.9	-0.8	-0.5	-0.0	1.1	0.8	1.3	-0.1	-0.2	0.9	-1.0	-1.5	0.5	-0.8
Prostate Cancer	0.2	0.2	1.3	0.6	0.2	0.4	0.0	0.5	0.4	-0.1	-0.0	0.1	-0.5	0.4	0.1	-0.1	-1.1	0.5	-0.0	1.0	0.8
Age at First Birth	0.2	0.2	0.9	0.9	-0.3	-0.0	-0.2	0.6	0.1	-0.5	-0.9	0.4	-0.6	0.7	-0.2	0.2	-0.1	0.1	-0.2	0.9	-0.1
Bipolar Disorder (2011)	1.3	1.2	4.8	1.8	-0.4	0.5	-0.9	2.2	-0.3	-0.1	0.8	0.9	0.4	2.1	1.0	-1.2	1.6	-0.8	-0.3	0.9	0.0
Body Mass Index (BMI) (2010)	0.1	0.2	1.1	-1.1	-0.4	-0.5	-0.4	-0.1	-0.6	-0.3	-0.0	0.4	0.4	0.0	-0.3	0.2	-0.4	0.3	-0.3	-0.2	-0.5
Coronary Artery Disease (CAD)	1.0	1.2	3.1	1.0	-1.3	-0.8	-1.5	1.8	-0.8	-0.9	-1.3	1.3	1.3	1.1	-0.5	0.1	1.3	-0.4	-1.6	0.4	-0.7
Crohns Disease (2012)	59.6	96.0	163.8	8.5	-12.2	-8.8	-12.8	12.2	-11.9	-10.6	-7.0	12.5	10.8	11.2	-8.4	7.5	0.0	-10.0	-11.4	7.7	0.0
Mean Putamen Volume	0.3	0.4	1.0	0.1	-0.5	-1.0	-0.4	0.3	-0.3	-0.6	-0.8	0.5	0.8	0.0	-0.8	0.8	-0.1	0.7	-0.3	0.9	-0.9
Fasting Glucose	0.3	0.3	1.0	0.9	-0.2	0.6	-0.1	0.8	-0.1	0.2	0.7	0.2	-0.2	0.8	0.4	-0.5	-0.0	-0.7	0.4	-1.0	-0.4
HbA1C	0.7	0.7	2.7	-0.1	0.5	0.8	1.0	-0.3	1.3	-0.4	-1.4	-0.5	-0.0	-0.2	-0.9	0.9	-0.8	0.1	1.1	0.9	1.7
HDL Cholesterol	0.5	0.8	2.0	-0.0	-1.0	-1.0	-1.4	1.1	-1.0	-0.3	0.3	0.9	1.4	0.5	0.1	-0.4	1.2	-0.9	-1.0	-1.2	-0.5
LDL Cholesterol	0.1	0.2	1.0	0.7	0.2	0.3	0.5	-1.0	0.1	-0.1	0.5	-0.3	-0.4	-0.8	-0.0	0.4	-0.4	0.1	0.4	-0.3	-0.2
Lupus	0.1	0.1	0.8	-0.0	0.1	0.4	0.2	-0.1	0.4	0.2	0.4	-0.2	-0.9	0.1	0.5	-0.2	0.1	-0.3	0.3	-0.7	0.5
Neuroticism (2016)	0.5	0.7	4.1	1.0	0.4	-0.8	-0.3	0.5	0.5	0.5	-0.1	0.0	0.0	0.2	0.5	-0.7	-1.8	1.6	0.1	0.4	2.0
Primary Biliary Cirrhosis	3.0	4.3	7.8	-0.3	-2.1	-1.4	-1.8	1.2	-2.2	-2.4	-2.0	2.1	2.8	1.1	-2.8	2.7	2.7	-2.2	-1.6	2.5	-1.6
Rheumatoid Arthritis	0.2	0.3	1.1	1.0	0.1	0.8	-0.1	0.1	0.0	0.2	0.8	-0.0	-0.1	0.4	0.8	-0.9	0.8	-0.9	0.0	-0.3	-0.6
Schizophrenia (2014)	0.1	0.2	1.3	-0.1	-0.2	0.3	-0.4	0.6	-0.3	-0.4	-1.1	0.4	-0.1	0.7	-0.0	0.2	-0.1	0.3	-0.2	0.1	-0.1
Triglycerides	0.5	0.8	2.1	1.2	-0.9	-0.3	-0.4	0.6	-0.8	-1.3	-1.1	0.7	0.5	0.6	-1.4	1.4	0.0	-0.8	-0.3	1.2	-0.9
Type 2 Diabetes (T2D) (2012)	0.4	0.5	2.3	0.9	-0.2	0.5	-0.2	0.9	0.3	-0.3	0.3	0.3	0.3	1.3	0.4	-0.5	1.5	-1.2	-0.3	0.1	-0.1
Ulcerative Colitis	1.9	2.7	5.3	1.0	-1.7	-1.9	-1.7	1.7	-1.7	-1.7	-2.3	1.8	1.3	1.3	-1.4	1.3	2.2	-0.8	-2.0	1.4	-1.5
Blood Eosinophil Count	0.5	4.1	11.5	-2.1	1.9	1.5	1.8	-2.6	0.9	2.9	3.4	-2.0	-2.3	-2.1	1.6	-1.8	-1.2	-0.7	2.1	-0.5	2.5
Blood Platelet Count	1.1	13.2	28.5	-1.9	4.5	4.5	4.3	-3.3	4.4	4.2	5.3	-4.1	-3.4	-2.2	3.9	-3.6	-2.4	2.5	4.5	-1.7	1.1
Blood Red Count	0.1	1.4	4.8	1.1	-1.5	-2.2	-1.5	1.2	-1.5	-1.1	-1.7	1.3	0.6	1.0	-1.2	0.8	0.2	0.2	-0.8	0.6	0.7
Blood White Count	0.3	2.3	5.2	-1.9	1.6	1.9	1.8	-1.5	1.6	1.1	1.6	-1.6	-1.4	-1.0	1.0	-0.7	-2.3	1.2	1.7	-1.1	1.1
Heel T-Score	0.0	0.4	2.1	-1.4	0.7	0.6	0.5	-0.4	0.2	0.2	0.3	-0.4	0.4	-0.5	0.1	-0.3	-0.9	0.1	1.2	0.3	-0.2
BMI	0.2	1.0	7.3	-1.0	0.8	0.6	0.7	-0.9	0.4	0.7	1.2	-0.8	-0.6	-1.1	0.8	-0.9	-0.3	0.1	0.9	-0.3	-2.7
Height	0.6	11.4	18.7	-3.7	4.1	3.0	4.3	-4.1	3.9	3.0	2.6	-4.0	-3.8	-2.8	2.2	-1.7	-4.1	3.5	4.2	-1.2	2.0
Waist Hip Ratio (WHR)	0.7	3.0	6.7	-0.3	-1.8	-2.6	-1.6	0.9	-2.0	-2.1	-1.8	1.7	1.8	0.5	-2.4	2.5	1.8	-1.0	-1.6	1.8	-0.2
Systolic Blood Pressure	0.2	1.1	4.9	0.7	-1.2	-1.8	-1.4	1.1	-0.9	-0.2	-0.7	1.1	0.5	0.7	-0.3	0.3	-0.9	0.8	-1.2	0.3	2.2
Smoking Status	0.9	2.1	4.1	-1.0	1.8	1.7	1.4	-0.5	1.7	1.8	1.0	-1.4	-1.4	-0.7	1.9	-2.0	-1.4	1.9	1.5	-0.4	1.0
Allergy or Eczema	2.7	7.1	15.0	0.4	-3.0	-2.5	-2.8	1.5	-3.5	-2.8	-1.7	2.9	2.9	1.8	-3.1	3.4	2.8	-3.9	-2.5	2.9	1.0
Cardiovascular Disease	3.4	11.3	18.1	2.3	-4.1	-4.1	-4.3	3.6	-4.2	-3.3	-3.3	4.2	3.8	3.2	-3.1	2.7	2.8	-1.0	-3.9	3.2	-0.1
Hypothyroidism (self reported)	0.2	0.5	2.1	0.7	-0.3	0.4	-0.6	0.4	-0.7	-0.7	0.3	0.6	1.1	1.1	0.1	0.1	1.5	0.0	-0.1	0.7	-1.2
Respiratory disease	0.2	0.5	1.9	0.7	-0.4	0.9	-0.6	0.8	-0.7	0.1	0.7	0.6	0.9	0.8	0.6	-0.7	1.1	-1.4	-0.4	-0.1	-0.1
Type 2 Diabetes (T2D) (2018)	1.7	3.2	8.3	0.4	2.1	2.2	2.1	0.1	2.9	2.1	2.2	-1.8	-1.2	-0.4	2.2	-2.2	-1.7	1.2	2.1	-0.5	1.4
Lung FEV1/FVC ratio	0.7	3.5	7.1	-0.4	-1.9	-0.9	-1.9	0.7	-2.5	-2.7	-2.2	2.0	2.2	0.9	-2.4	2.3	2.4	-1.6	-2.0	1.6	-0.7
Lung FVC	0.2	1.0	9.1	3.0	-0.5	-1.2	-0.5	1.3	0.5	-0.4	-1.5	0.4	0.5	0.7	0.1	-0.3	-0.1	1.0	-0.9	0.7	0.0
Neuroticism	1.2	2.9	8.6	2.9	-1.6	-1.0	-1.9	2.4	-1.6	-1.5	-1.7	1.9	1.7	1.9	-1.0	0.7	0.9	-0.6	-1.8	2.1	1.8
Chronotype (morning person)	0.6	1.4	4.4	-0.7	1.4	0.8	1.3	-2.1	1.1	1.2	0.9	-1.4	-1.6	-1.4	0.9	-0.8	-0.3	1.1	1.3	-1.2	0.7
Hair Pigment	0.1	1.5	3.3	1.8	-1.7	-1.5	-1.8	1.6	-1.7	-0.9	-0.6	1.4	-0.1	1.6	-0.4	0.0	0.0	-1.0	-1.7	0.1	0.8
Tanning	0.1	1.7	4.5	-2.1	1.2	1.6	1.1	-0.7	1.3	1.6	2.1	-1.0	-1.0	0.3	1.6	-1.3	0.1	0.9	1.2	0.7	-1.3
Hand grip strength (left)	0.1	0.2	1.0	-0.2	0.3	-0.4	0.3	-0.3	0.5	0.1	-0.6	-0.3	-0.0	-0.8	-0.2	0.0	-0.9	1.0	-0.2	0.1	0.6
Number of treatments/medications taken	0.7	1.3	3.1	0.9	-1.3	-1.1	-1.5	1.8	-1.4	-1.1	-0.6	1.5	1.6	1.2	-0.8	0.5	0.9	-0.3	-1.3	1.1	-0.8
Average weekly spirits intake	0.5	0.6	1.2	0.5	-0.8	-1.1	-0.6	0.8	-0.5	-0.4	-0.9	0.7	1.1	1.0	-0.8	0.7	0.8	-0.4	-0.4	1.0	-0.9
Sensitivity / hurt feelings	0.2	0.3	1.2	0.3	0.3	0.6	-0.4	0.4	-0.3	0.6	1.1	0.2	-0.4	0.2	0.8	-0.9	0.2	0.0	-0.1	0.3	0.7
Frequency of depressed mood in last 2 weeks	2.3	3.3	8.4	2.7	-1.7	-1.3	-2.1	2.9	-1.5	-0.8	-1.4	2.0	2.2	2.9	-0.5	0.1	1.1	-0.5	-1.8	2.1	1.7
Hearing difficulty/problems: Yes	0.3	0.5	1.3	0.5	-0.3	-0.2	-0.4	0.9	-0.3	-0.8	-1.0	0.5	0.8	0.9	-0.6	0.3	0.9	-0.5	-0.7	1.1	1.1
Relative age of first facial hair	2.0	4.0	8.1	2.0	-2.1	-1.9	-2.2	2.4	-1.7	-2.1	-2.6	2.2	2.0	2.6	-1.9	1.5	1.3	-0.4	-2.1	2.9	0.4
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.9	1.1	-0.8	-0.6	-0.9	1.4	-0.5	-0.6	-0.9	0.9	1.0	1.2	-0.4	0.2	0.8	0.1	-1.0	0.8	0.2
Ever used hormone-replacement therapy (HRT)	3.2	4.1	7.2	-0.6	2.4	2.2	2.3	-1.4	2.6	2.4	2.7	-2.3	-2.1	-1.5	2.4	-2.4	-1.5	1.2	2.4	-1.7	0.2
Ever had hysterectomy (womb removed)	0.4	0.4	3.6	-0.7	-0.1	-0.2	-0.1	-0.8	-0.8	-0.6	0.3	0.1	-0.4	0.1	-0.3	1.0	0.4	-1.9	0.2	0.1	-0.5
Systolic blood pressure, automated reading	0.0	0.1	0.4	-0.3	0.1	-0.4	0.1	-0.2	0.4	0.4	0.5	-0.2	-0.6	0.0	0.6	-0.3	-0.2	0.4	0.2	-0.6	0.0
Eye problems/disorders: Diabetes related eye disease	2.1	2.3	5.6	-0.9	1.8	1.3	1.9	-0.8	2.1	1.9	2.4	-1.8	-1.5	-0.9	1.7	-1.4	-0.7	1.0	1.9	-1.0	-0.2
Angina	1.1	1.4	4.1	0.8	-1.5	-1.0	-1.6	1.9	-1.5	-1.0	-0.5	1.6	0.8	0.8	-0.7	0.4	1.6	-1.2	-2.0	0.2	0.4
Medication for hormone replacement therapy	1.2	1.3	3.7	-0.2	1.4	1.9	1.3	-0.4	1.3	1.2	1.1	-1.1	-0.9	-0.4	1.5	-1.4	-1.4	1.1	1.1	-0.5	0.8
Vitamin and mineral supplements	0.2	0.3	1.1	-0.9	0.4	0.3	0.6	-1.0	0.2	0.2	0.4	-0.5	-0.8	-0.4	-0.2	0.2	0.6	-0.1	0.5	0.7	0.8
Supplements: Zinc	0.7	0.7	2.2	-0.5	-1.0	-0.8	-1.2	0.2	-1.5	-0.8	-0.0	1.0	1.1	0.4	-0.4	0.6	0.8	-1.2	-0.6	0.3	-1.2
Medication: Co-codamol	1.6	1.9	5.4	0.5	-1.3	-1.5	-1.4	1.2	-1.2	-1.4	-1.1	1.5	1.7	2.1	-1.4	1.5	1.1	0.1	-1.1	2.3	-1.0
Medication: Metformin	1.2	1.7	4.9	-0.3	1.6	1.6	1.7	-0.3	2.2	1.6	1.8	-1.5	-1.0	-0.5	1.4	-1.6	-0.2	0.5	1.6	-0.5	0.6
Diabetes (father)	0.6	0.7	3.1	1.2	-0.2	1.3	-0.5	1.3	0.1	0.1	0.6	0.4	-0.1	1.3	0.9	-1.0	0.3	-1.8	0.3	-0.3	-0.5
Diabetes (mother)	1.3	1.7	5.2	1.0	-1.4	-1.1	-1.4	1.4	-1.1	-1.1	-0.8	1.4	1.4	1.4	-1.2	1.1	2.3	-1.4	-1.1	1.3	-0.9
Severe depression (siblings)	1.2	1.4	3.0	-0.4	-1.3	-1.4	-1.1	0.2	-1.4	-1.4	-1.7	1.1	1.4	0.6	-1.6	1.5	0.8	-0.9	-1.7	0.7	-0.6
Pack years adult smoking proportion	0.2	0.3	0.9	-0.7	0.5	-0.0	0.5	-0.8	0.4	0.2	-0.5	-0.6	-0.8	-0.5	0.4	-0.1	-0.7	0.6	0.6	-0.9	-0.4
Impedance of leg (right)	1.1	5.3	9.8	0.9	-2.6	-3.1	-2.5	1.9	-2.3	-2.9	-3.0	2.5	2.6	1.7	-2.9	2.9	1.3	-1.1	-2.3	2.0	-0.3
Leg fat-free mass (left)	0.9	4.7	8.2	-1.1	2.5	2.7	2.5	-1.8	2.5	2.7	2.6	-2.4	-2.9	-1.6	2.5	-2.7	-1.4	0.9	2.5	-1.3	0.2
Trunk fat percentage	0.2	1.0	15.4	-0.6	-0.1	-0.4	-0.2	-0.2	-0.4	-0.1	0.3	0.2	-0.2	-0.2	-0.0	-0.1	1.0	0.1	0.3	0.5	-3.9
Hand grip strength (right)	0.3	0.7	1.5	1.2	-0.6	-1.1	-0.7	0.9	-0.3	-0.7	-1.1	0.7	0.7	0.3	-0.8	0.6	-0.2	0.7	-1.0	1.2	1.1
Townsend deprivation index at recruitment	0.2	0.3	1.5	0.6	0.3	-0.5	-0.0	0.2	0.1	0.2	-0.7	0.1	-0.4	0.8	0.1	-0.4	0.2	0.5	-0.9	1.2	1.1
Current tobacco smoking	0.7	1.2	6.3	0.8	1.0	1.2	0.8	0.6	1.5	1.2	-0.3	-0.7	-0.4	0.1	1.3	-1.6	-1.3	1.0	0.6	0.2	2.5
Average weekly fortified wine intake	1.2	1.4	2.8	0.8	-1.4	-0.9	-1.4	1.1	-1.6	-1.0	-0.2	1.4	1.7	1.2	-1.0	0.9	1.6	-1.2	-1.4	0.6	-0.2
Maternal smoking around birth	0.1	0.2	1.7	0.4	0.4	-0.2	0.4	-0.2	0.4	0.6	0.2	-0.4	-0.0	-0.4	0.3	-0.6	-0.4	-0.3	-0.2	-0.1	1.3
Fed-up feelings	0.6	1.1	3.4	1.8	-0.8	-0.7	-1.4	1.9	-0.8	-0.3	-0.5	1.1	0.9	1.0	0.1	-0.6	0.1	0.0	-1.1	0.7	1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.5	1.2	0.3	0.2	-0.1	0.8	0.3	0.9	0.1	0.0	-0.0	1.0	0.9	-1.2	0.1	1.0	0.2	0.8	1.2
Relative age voice broke	5.0	7.7	12.2	2.4	-3.4	-2.2	-3.2	3.5	-2.7	-3.2	-2.6	3.3	2.7	3.4	-2.8	2.2	2.8	-1.8	-2.9	2.7	0.3
Taking other prescription medications	0.2	0.3	1.2	0.6	-0.1	0.4	-0.2	0.7	-0.1	0.6	1.1	0.3	-0.1	0.9	0.7	-1.0	0.5	0.4	-0.1	0.5	0.2
Age when periods started (menarche)	0.2	0.5	1.5	0.2	-0.8	-0.0	-0.9	0.5	-1.2	-0.7	0.2	1.1	1.2	0.8	-0.7	0.5	0.2	0.5	-0.7	0.5	0.3
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.7	-0.6	0.7	-0.0	0.7	-0.8	0.6	0.3	0.8	-0.8	-0.4	-0.3	0.4	-0.0	0.0	-0.4	0.2	-0.1	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	1.2	0.4	0.5	1.1	0.1	0.0	0.2	0.6	0.7	-0.1	0.0	0.1	0.8	-1.0	-0.1	0.3	0.2	-0.1	-0.0
Tinnitus: Yes, but not now, but have in the past	3.1	3.3	6.0	0.9	-2.2	-1.8	-2.0	2.0	-1.8	-1.9	-1.0	2.1	2.4	1.9	-2.1	1.8	1.7	-2.2	-1.2	1.7	-0.4
Qualifications: CSEs or equivalent	0.2	0.3	1.0	-0.9	0.3	-0.8	0.4	-1.0	-0.1	0.3	0.0	-0.4	-0.8	-0.7	-0.4	0.3	-0.7	-0.1	-0.4	-0.0	0.8
Serious illness, injury or assault to yourself	1.5	1.8	3.8	-1.9	1.3	0.7	1.5	-1.6	1.2	1.4	0.8	-1.5	-1.3	-2.0	0.6	-0.7	-1.7	1.5	1.0	-0.9	1.7
High blood pressure	2.8	7.9	13.0	1.5	-3.3	-3.6	-3.5	3.1	-3.3	-2.7	-2.8	3.4	3.1	2.8	-2.6	2.2	2.8	-0.6	-3.4	2.9	0.2
Hayfever, allergic rhinitis or eczema	3.1	6.8	12.0	1.1	-2.9	-2.7	-2.9	1.9	-3.2	-2.8	-2.6	3.0	2.6	2.2	-3.0	3.1	2.2	-2.2	-2.7	3.5	1.3
Multivitamins +/- minerals	0.2	0.3	1.0	0.9	-0.4	-0.7	-0.5	0.7	-0.3	-0.6	-1.0	0.5	0.8	0.4	-0.3	0.3	-0.3	0.1	-0.7	0.0	-0.1
Stomach or abdominal pain in last month	0.2	0.3	1.4	-0.1	0.5	0.7	0.5	-0.5	0.5	0.4	-0.4	-0.5	-0.1	-0.4	0.4	-0.5	-1.2	0.6	0.4	-0.5	0.1
Supplements: Glucosamine	0.8	1.1	2.9	-1.2	1.1	0.5	0.9	-1.7	0.4	1.1	1.1	-1.2	-0.6	-1.4	0.9	-0.9	-0.7	0.8	0.9	-1.5	-0.1
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	3.4	0.4	-1.2	-1.8	-1.1	-0.0	-1.4	-0.9	-1.4	0.8	0.8	-0.4	-1.1	1.1	0.3	-1.1	-1.7	0.3	-0.2
Medication: Atenolol	0.2	0.2	1.3	0.1	-0.1	-0.9	-0.3	-0.1	-0.5	-0.1	0.2	0.2	-0.4	0.1	0.1	-0.0	0.3	0.4	-0.6	0.1	-1.1
Medication: Levothyroxine sodium	0.1	0.2	1.3	-0.0	0.2	-0.1	0.1	-0.0	-0.1	-0.6	0.3	0.1	0.4	0.5	-0.3	0.4	1.0	0.2	0.4	1.1	0.2
Sitting height	0.1	0.8	2.5	0.3	0.7	0.8	0.5	-0.0	0.9	1.2	1.6	-0.6	-1.4	0.9	1.2	-1.4	-0.2	0.0	0.8	-0.1	0.8
Chronic bronchitis/emphysema (father)	0.5	0.6	3.1	0.4	-0.5	-0.4	-0.6	0.4	-0.9	-0.5	0.1	0.7	0.4	1.2	-0.4	0.4	1.8	-0.2	-0.6	1.2	-1.4
High blood pressure (mother)	1.4	1.9	3.4	1.0	-1.7	-1.3	-1.9	1.8	-1.6	-1.3	-0.6	1.7	1.7	1.8	-0.6	0.5	1.6	-1.6	-1.3	0.5	-1.1
Body mass index (BMI)	0.3	1.1	7.8	-0.7	0.8	0.9	0.7	-0.7	0.5	0.9	1.4	-0.8	-0.9	-0.6	1.0	-1.2	0.5	-0.4	1.0	-0.2	-2.8
Impedance of leg (left)	0.5	2.3	5.7	-0.5	-1.6	-2.4	-1.5	0.6	-1.6	-2.0	-2.0	1.5	1.8	0.5	-2.1	2.2	0.4	-0.3	-1.4	1.0	-0.6
Leg predicted mass (left)	0.9	4.7	8.1	-1.0	2.5	2.7	2.5	-1.7	2.5	2.8	2.6	-2.4	-2.8	-1.5	2.5	-2.8	-1.3	0.9	2.4	-1.2	0.2
Trunk fat mass	0.3	1.2	11.4	-1.2	0.8	0.4	0.7	-0.9	0.5	0.7	1.0	-0.7	-1.0	-0.8	0.6	-0.8	0.3	0.4	1.1	-0.0	-3.4
Waist circumference	0.2	0.6	6.2	-0.9	0.2	0.1	0.1	-0.2	-0.2	0.2	1.0	-0.1	-0.3	-0.1	0.2	-0.3	1.2	-0.1	0.5	0.6	-2.5
Number of incorrect matches in round	1.7	2.8	6.0	0.8	-1.6	-1.8	-1.5	1.3	-1.7	-2.1	-1.9	1.7	2.0	0.9	-2.2	2.3	0.7	-0.7	-1.8	2.5	0.3
Past tobacco smoking	0.7	1.2	2.2	1.3	-1.4	-1.0	-1.1	1.0	-1.2	-1.4	-0.8	1.1	1.1	0.5	-1.1	1.2	0.7	-1.2	-1.2	0.1	1.5
Alcohol usually taken with meals	0.6	0.9	4.3	-1.3	0.7	0.8	0.6	-1.3	0.4	0.8	1.0	-0.8	-0.6	-0.7	0.9	-0.7	-0.1	-0.0	0.6	-1.7	-2.1
Nervous feelings	2.2	4.0	9.5	1.6	-2.1	-2.3	-2.1	2.0	-1.8	-2.1	-3.1	2.2	2.4	1.9	-2.2	1.9	-0.0	-0.1	-2.2	2.5	0.9
Frequency of tenseness / restlessness in last 2 weeks	2.2	3.4	7.2	2.6	-1.7	-1.3	-2.1	2.5	-1.7	-1.1	-2.2	2.1	1.8	2.7	-0.8	0.4	1.2	-0.8	-2.1	1.9	2.1
Hearing difficulty/problems with background noise	1.8	2.9	5.3	1.5	-1.6	-1.8	-1.6	1.4	-1.7	-2.0	-2.3	1.8	1.4	1.6	-2.1	1.8	1.8	-1.2	-1.8	2.2	0.3
Hair/balding pattern: Pattern 2	2.0	2.6	5.0	-2.2	1.5	0.7	1.7	-1.5	1.5	1.6	2.0	-1.8	-1.6	-1.9	1.0	-1.2	-2.0	1.1	1.6	-2.2	-0.2
Had menopause	1.4	1.7	4.6	-0.6	1.5	1.6	1.3	-1.1	1.4	1.4	2.1	-1.3	-1.0	-0.5	1.7	-1.6	-0.8	1.4	1.1	-1.3	0.9
Had other major operations	0.5	0.6	1.6	1.2	-0.4	-0.3	-0.5	0.8	-0.5	-0.4	0.5	0.5	-0.2	1.2	-0.3	0.2	1.3	-1.2	-1.2	0.8	0.9
Forced vital capacity (FVC)	0.4	1.4	5.3	0.6	1.2	0.5	1.4	-0.7	1.8	1.2	0.2	-1.3	-1.6	-1.0	0.7	-0.6	-1.5	1.1	1.2	0.2	2.3
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.2	0.6	-0.3	0.3	-0.8	0.8	-0.7	-0.5	-0.1	0.7	1.1	1.0	-0.0	-0.0	1.0	-0.4	-0.7	1.0	-0.1
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	1.3	-0.6	-0.1	0.2	-0.2	0.2	-0.4	-0.3	-0.2	0.2	0.7	-0.1	-0.0	-0.0	-0.2	-0.8	-0.2	-0.7	1.1
Qualifications: None of the above	0.1	0.1	0.9	0.9	-0.0	-0.1	-0.2	0.7	-0.0	-0.2	-0.2	0.2	-0.1	0.2	0.2	-0.3	0.0	-0.3	-0.2	-0.3	0.5
Financial difficulties in last 2 years	1.6	2.2	6.0	1.6	-1.5	-1.5	-1.7	2.1	-1.5	-1.1	-1.2	1.6	1.7	1.4	-1.0	0.7	1.4	-0.9	-2.5	1.3	1.0
Mouth/teeth dental problems	1.0	1.6	6.0	1.6	-1.3	0.3	-1.4	1.6	-1.2	-1.1	-0.3	1.3	1.1	1.1	-0.4	0.2	2.1	-2.4	-0.4	0.0	-1.4
Heart attack	1.4	1.8	4.2	1.3	-1.3	-1.0	-1.6	1.5	-1.5	-1.6	-1.5	1.6	1.1	1.1	-0.9	1.2	0.9	-0.8	-2.0	1.6	0.8
Allergy	1.9	4.5	7.3	-0.7	2.3	1.9	2.5	-1.8	2.7	2.0	1.8	-2.5	-2.3	-2.2	2.2	-2.2	-2.0	2.0	2.1	-2.7	-1.1
Pain all over the body in last month	2.3	2.5	4.4	-0.2	1.5	2.0	1.4	-1.2	1.6	2.0	1.8	-1.6	-1.8	-0.9	2.1	-2.0	-1.1	-1.7	1.2	-1.6	1.4
Diabetes (self-reported)	0.4	0.6	2.6	0.8	0.9	1.0	0.9	0.7	1.6	0.7	1.0	-0.6	-0.2	0.3	0.9	-0.9	-0.1	0.1	0.9	0.4	0.2
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	2.4	-0.3	-0.7	-0.4	-0.5	0.1	-0.9	-0.6	-0.0	0.7	0.6	0.5	-0.9	1.0	0.4	-1.0	-0.4	1.2	1.5
Medication: Ramipril	1.2	1.5	6.2	-2.5	0.9	0.4	0.8	-1.3	0.4	1.1	0.4	-0.9	-0.2	-2.0	0.7	-0.7	-1.9	1.9	0.5	-1.7	0.5
Medication: Simvastatin	0.2	0.3	0.8	0.2	0.7	0.2	0.8	-0.1	0.9	0.6	0.6	-0.6	-0.6	-0.6	0.5	-0.4	-0.8	0.4	0.6	0.1	0.9
Fluid intelligence score	0.3	0.6	4.5	0.5	0.5	0.3	0.9	-1.0	0.8	0.2	-0.2	-0.7	-1.1	0.1	0.0	0.4	0.5	-0.3	0.7	0.2	-2.1
Illnesses of siblings	2.4	3.4	6.5	-1.1	2.1	2.1	2.2	-1.7	2.5	1.8	1.1	-2.2	-2.0	-1.6	1.7	-1.6	-1.9	1.8	2.5	-1.1	-0.4
Neuroticism score	1.3	2.7	7.5	2.7	-1.4	-1.0	-1.8	2.4	-1.3	-1.1	-1.9	1.8	1.4	1.9	-0.8	0.3	0.6	-0.5	-1.7	1.8	2.4
Weight	0.6	2.7	5.3	-1.5	1.8	1.7	1.7	-1.5	1.5	1.9	2.3	-1.7	-2.0	-1.3	1.8	-1.9	-0.4	0.2	1.9	-0.9	-1.8
Impedance of arm (right)	1.1	5.1	9.1	1.2	-2.7	-2.8	-2.7	2.1	-2.5	-2.7	-3.0	2.6	2.0	1.8	-2.6	2.6	1.7	-1.0	-2.5	1.7	0.2
Arm fat percentage (right)	0.3	1.1	14.4	-0.3	-0.4	-0.3	-0.5	0.4	-0.7	-0.2	0.4	0.4	0.1	0.2	-0.0	-0.2	1.4	-1.0	0.0	0.4	-3.8
Trunk fat-free mass	0.6	3.4	6.1	-1.5	2.1	2.4	2.1	-1.6	2.0	2.3	2.5	-2.0	-2.0	-1.2	2.0	-2.3	-1.4	0.1	2.0	-1.2	0.9
Hip circumference	0.3	1.3	3.4	-1.0	1.2	1.0	0.9	-0.7	0.9	1.5	1.7	-1.0	-1.2	-0.5	1.4	-1.6	-0.1	0.6	1.3	-0.2	-1.9
Time employed in main current job	0.1	0.1	0.3	-0.6	0.3	0.4	0.2	0.2	0.4	-0.0	-0.4	-0.1	0.4	-0.3	0.3	-0.0	-0.4	0.5	0.3	0.5	0.3
Alcohol intake versus 10 years previously	0.8	1.2	3.4	-0.3	-1.2	-1.6	-0.9	0.4	-1.2	-1.1	-0.2	1.1	0.3	0.7	-1.7	1.9	1.4	-0.8	-1.1	1.2	-0.6
Father’s age at death	0.1	0.2	0.7	0.8	-0.0	0.6	0.2	-0.0	0.3	-0.5	-0.4	-0.0	-0.2	0.4	-0.1	0.6	0.2	-0.8	0.5	0.4	0.2
Worrier / anxious feelings	1.1	2.1	6.2	2.3	-1.3	-1.3	-1.5	1.9	-0.9	-1.4	-2.1	1.6	0.8	1.3	-1.4	1.2	0.8	0.6	-1.1	2.5	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	3.6	1.5	0.5	1.0	-0.2	1.1	0.4	0.9	0.4	-0.0	-0.0	1.2	1.6	-1.9	-0.3	-0.5	0.0	0.1	0.6
Falls in the last year	1.1	1.5	3.8	1.0	-1.4	-0.5	-1.6	1.9	-1.5	-0.8	-0.2	1.6	1.5	1.7	-0.3	-0.0	0.6	-1.6	-1.4	0.5	0.9
Hair/balding pattern: Pattern 3	0.6	0.8	4.8	1.0	-0.7	0.4	-0.8	0.6	-1.2	-0.6	0.3	0.7	-0.1	0.5	0.1	-0.2	1.0	-2.2	-0.8	-0.8	-1.6
Number of live births	0.4	0.5	4.1	0.5	0.3	-0.1	0.2	0.9	0.7	0.4	1.0	-0.1	0.1	0.5	0.5	-0.7	0.4	0.7	0.6	0.8	-2.0
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	2.1	0.3	0.9	0.7	1.1	-0.6	1.3	0.8	0.1	-1.0	-1.1	-1.0	0.5	-0.4	-1.1	0.7	0.9	0.1	1.5
Pulse rate	0.7	1.2	2.8	0.0	-1.1	-1.2	-1.1	0.7	-1.1	-1.2	-1.2	1.1	1.6	0.8	-1.3	1.3	1.2	-0.4	-0.5	1.0	-1.7
Happiness	3.7	4.5	8.8	2.3	-2.1	-1.9	-2.3	2.7	-1.8	-1.8	-2.5	2.4	2.3	2.2	-1.9	1.4	0.5	-0.4	-2.3	3.0	2.5
Noisy workplace	0.9	1.1	3.1	-0.6	0.7	0.5	0.9	-0.1	1.0	1.2	1.1	-0.9	-0.6	-1.2	0.9	-1.4	-1.1	1.8	1.2	-1.6	0.9
Qualifications: A levels/AS levels or equivalent	0.2	0.3	1.9	1.4	-0.3	0.3	-0.2	0.3	-0.0	-0.6	-0.7	0.3	-0.3	0.9	-0.5	0.7	0.1	-0.8	0.4	0.5	-0.6
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	3.6	-1.5	1.2	1.4	1.4	-1.3	1.4	0.7	0.9	-1.3	-0.9	-1.9	0.7	-0.7	-1.5	1.2	0.9	-1.1	-0.4
Mouth/teeth dental problems: Dentures	0.4	0.6	1.6	-1.0	0.9	-0.4	1.2	-1.2	0.8	0.5	0.7	-1.0	-0.6	-1.3	-0.2	0.4	-1.0	0.7	0.4	-0.2	-0.1
Asthma	2.1	4.2	7.0	2.0	-2.1	-0.8	-2.5	2.5	-2.5	-1.7	-0.7	2.5	2.4	2.6	-1.2	0.9	2.6	-2.3	-2.4	2.1	-0.9
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	7.6	1.2	-0.4	-1.1	-0.3	0.3	-0.5	-1.0	-2.8	0.5	0.6	0.1	-1.5	1.6	0.5	0.3	-1.1	2.0	1.5
Medication: Cholesterol lowering	0.1	0.2	1.7	1.3	0.1	-0.5	0.2	0.3	0.3	0.1	-0.5	-0.0	-0.4	-0.2	0.0	-0.2	-0.5	0.6	-0.1	0.2	-0.0
Depression (self-reported)	0.8	1.0	4.8	1.7	-0.6	-0.2	-0.9	1.0	-0.6	-0.3	-0.6	0.9	0.8	1.7	-0.3	0.1	1.1	0.0	-0.5	2.2	0.9
Medication: Lansoprazole	0.3	0.4	1.8	1.4	-0.4	-1.0	-0.5	0.8	-0.3	0.0	-0.2	0.4	0.5	0.4	-0.1	-0.3	0.2	0.2	-1.1	0.1	0.7
Prospective memory result	0.3	0.3	2.0	-0.2	-0.1	0.5	-0.6	0.5	-0.5	-0.1	0.8	0.4	0.9	0.2	0.7	-0.5	-0.3	-0.2	-0.6	0.1	1.4
Lung cancer (father)	1.1	1.3	6.6	2.1	-0.9	-0.7	-1.2	1.9	-0.8	-0.3	-0.4	1.0	0.1	1.1	0.5	-0.7	0.0	-0.5	-0.9	-0.9	2.6
Illnesses of mother	0.9	1.2	4.7	-2.2	1.0	0.3	1.4	-2.1	0.8	0.4	-0.1	-1.2	-0.7	-1.3	-0.4	0.6	-1.3	1.1	1.0	-0.0	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	1.3	0.6	0.5	0.3	0.7	-0.4	1.0	0.5	-0.1	-0.6	-1.1	-0.8	0.3	-0.3	-0.9	0.5	0.6	-0.2	0.4
Pulse wave Arterial Stiffness index	0.7	0.8	2.7	0.7	-0.8	0.2	-1.3	1.0	-1.4	-0.4	0.6	1.1	0.9	1.1	0.3	-0.1	1.7	-1.0	-1.0	0.4	-0.4
Impedance of arm (left)	0.4	1.7	3.2	1.1	-1.5	-1.6	-1.6	1.4	-1.4	-1.5	-1.8	1.6	1.0	1.0	-1.4	1.4	0.9	0.0	-1.5	0.8	0.0
Arm fat mass (right)	0.2	0.9	9.2	-0.7	0.5	0.6	0.4	-0.3	0.3	0.7	1.2	-0.5	-0.7	-0.3	0.8	-1.0	0.6	-0.6	0.8	0.0	-3.0
Trunk predicted mass	0.6	3.4	5.9	-1.5	2.1	2.4	2.1	-1.6	2.0	2.3	2.4	-2.0	-2.0	-1.2	2.0	-2.2	-1.4	0.1	2.0	-1.1	1.0
Standing height	0.3	3.3	5.7	-1.7	2.0	1.8	2.0	-1.8	2.2	2.0	2.0	-2.0	-2.4	-1.2	1.6	-1.6	-1.7	1.2	2.0	-1.2	1.8
Length of working week for main job	0.9	1.0	2.5	-0.0	-0.9	-1.2	-0.7	-0.1	-1.1	-1.0	-1.4	0.8	1.1	0.3	-1.3	1.6	0.5	-1.1	-0.9	1.2	0.9
Exposure to tobacco smoke at home	0.8	0.9	3.0	-0.8	1.3	0.7	1.1	-0.5	1.4	0.6	0.0	-1.1	-0.9	-0.5	0.7	-0.7	-1.6	1.7	1.0	-0.3	0.6
Breastfed as a baby	4.5	5.5	10.1	1.0	-2.6	-2.3	-2.4	1.9	-2.7	-3.0	-2.4	2.6	2.1	2.1	-3.0	3.2	1.9	-1.5	-2.7	2.6	0.2
Tense / ‘highly strung’	3.0	4.9	12.0	1.6	-2.4	-2.7	-2.3	2.0	-1.9	-2.1	-3.5	2.3	2.1	1.8	-2.4	2.1	1.1	-0.0	-2.6	2.5	2.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	9.2	0.7	0.4	-0.3	0.6	-0.3	0.9	0.5	-0.8	-0.6	-0.7	-0.4	0.1	-0.2	-1.4	0.6	-0.0	0.2	3.0
Hair/balding pattern: Pattern 4	0.2	0.4	2.3	1.5	-0.3	0.5	-0.7	0.7	-0.3	-0.2	-0.3	0.6	-0.0	0.9	0.3	-0.3	0.5	-1.0	-0.2	0.9	0.7
Birth weight of first child	1.1	2.0	6.0	-1.1	1.4	1.8	1.1	-1.7	0.6	1.6	2.4	-1.4	-1.1	-1.1	1.8	-1.8	-0.8	-0.6	1.3	-1.8	0.7
Peak expiratory flow (PEF)	0.2	0.5	1.5	1.2	-0.7	-0.1	-0.6	0.9	-0.5	-0.7	-0.9	0.7	0.5	0.3	-0.5	0.4	1.0	-0.8	-0.3	1.0	0.5
Pulse wave reflection index	0.7	0.8	2.0	0.6	-0.9	-0.3	-1.0	1.0	-1.2	-0.8	-0.4	1.1	1.0	1.3	-0.6	0.7	0.8	-0.6	-0.8	1.4	0.7
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.6	-0.3	0.8	0.6	0.8	0.2	1.2	1.0	0.3	-0.7	-0.7	0.1	0.9	-0.9	-0.7	0.6	1.1	-0.4	-0.9
Loud music exposure frequency	0.4	0.5	2.8	-0.0	0.6	0.1	0.7	-0.7	0.4	0.5	0.2	-0.5	-0.2	-0.7	0.0	-0.2	-0.8	1.7	0.1	0.2	1.4
Qualifications: O levels/GCSEs or equivalent	1.2	1.9	4.6	-0.6	1.4	1.3	1.6	-1.2	1.6	1.6	1.6	-1.5	-2.1	-1.1	1.5	-1.0	-1.3	1.0	1.7	-1.4	0.4
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	8.2	0.7	0.3	0.6	0.2	0.4	0.6	0.3	-0.7	-0.1	-0.1	0.6	0.3	-0.5	-0.8	1.3	-0.3	0.6	2.9
Blood clot in the leg (DVT)	1.3	1.7	7.1	-0.4	1.2	1.0	1.2	-0.5	1.1	1.2	1.1	-1.1	-1.1	-0.9	1.1	-1.0	-2.4	1.2	0.9	-0.9	2.7
Medication: Paracetamol	1.5	2.5	5.5	1.3	-1.7	-1.9	-2.0	2.4	-1.7	-1.6	-0.4	2.0	2.0	1.8	-1.1	0.9	1.4	-0.4	-1.8	1.7	-1.0
Headache pain in last month	0.1	0.2	1.0	0.3	0.2	0.1	-0.1	-0.0	-0.2	0.5	0.5	-0.2	-0.3	-0.4	0.8	-0.9	-0.2	0.0	-0.3	-0.7	1.0
Medication for cholesterol, blood pressure or diabetes	1.3	2.2	6.6	-1.2	1.7	2.6	1.7	-1.3	1.8	1.2	1.4	-1.7	-1.6	-0.8	1.5	-1.0	-1.4	0.4	1.9	-0.8	1.2
Glaucoma (self-reported)	7.5	8.9	16.2	0.4	3.4	3.8	3.1	-1.1	3.9	3.6	4.0	-3.1	-2.9	-0.9	3.9	-4.0	-2.1	1.5	3.7	-2.6	-0.7
Gout (self-reported)	0.2	0.2	1.0	-1.0	-0.1	-0.1	-0.4	-0.7	-0.9	-0.3	-0.5	0.2	0.3	-0.3	-0.2	0.6	0.7	0.2	-0.1	-0.0	-0.4
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.9	-0.4	0.5	0.6	0.5	-0.8	0.1	-0.1	1.0	-0.3	0.1	0.1	0.2	0.2	0.3	0.4	0.8	0.2	-0.8
Medication: Amlodipine	1.4	2.0	4.3	1.3	-1.5	-1.3	-1.5	2.1	-0.9	-1.5	-0.9	1.6	1.4	2.1	-1.2	1.0	1.6	-0.4	-1.5	1.5	1.5
Medication: Ventolin 100micrograms inhaler	0.7	0.8	3.1	0.5	-0.9	-0.7	-1.3	1.8	-0.7	-0.6	0.3	1.2	1.4	1.3	0.0	-0.1	1.0	-1.0	-0.9	0.4	0.2
Birth weight	1.7	3.8	10.1	-0.9	2.4	3.2	2.1	-2.0	1.9	2.3	1.9	-2.1	-2.2	-1.4	2.4	-2.1	-1.0	-0.3	2.3	-1.2	0.4
Chronic bronchitis/emphysema (mother)	0.3	0.4	2.3	-0.3	0.7	0.8	0.6	0.1	0.6	0.3	-0.3	-0.3	-0.3	-0.8	0.4	-0.3	-0.7	1.5	0.4	0.4	0.9
High blood pressure (siblings)	1.4	2.1	4.3	1.4	-1.6	-1.8	-1.7	1.2	-2.0	-1.3	-1.0	1.7	1.5	1.1	-1.3	1.2	1.2	-0.7	-2.1	0.8	1.4
Forced vital capacity (FVC), Best measure	0.4	1.3	3.5	0.8	1.2	0.6	1.3	-0.7	1.8	1.4	0.4	-1.3	-1.9	-1.0	1.0	-1.0	-1.6	1.0	1.2	-0.4	0.8
Body fat percentage	0.3	1.2	18.1	-0.9	0.1	-0.2	0.0	-0.4	-0.3	0.1	0.7	-0.1	-0.4	-0.4	0.2	-0.3	0.9	-0.1	0.6	0.2	-4.2
Leg fat percentage (right)	0.3	1.2	15.8	-1.3	-0.2	-0.6	-0.2	-0.3	-0.7	-0.3	0.3	0.2	0.2	-0.2	-0.5	0.3	1.1	-0.9	0.4	0.6	-4.0
Arm fat-free mass (right)	1.3	6.5	10.6	-2.0	3.0	2.9	2.9	-2.4	2.8	3.1	3.3	-2.9	-2.8	-1.9	2.8	-3.0	-2.1	1.4	2.8	-1.7	-0.1
Exposure to tobacco smoke outside home	0.1	0.2	0.8	-0.6	0.3	-0.8	0.1	-0.5	-0.1	0.4	0.1	-0.2	-0.3	-0.0	-0.0	-0.1	-0.2	0.9	-0.6	-0.1	-0.2
Comparative body size at age 10	0.1	0.3	1.1	-0.6	0.6	1.0	0.5	-0.7	0.2	0.5	0.1	-0.5	0.0	-0.2	0.4	-0.4	-0.1	-0.5	0.8	0.3	0.2
Number of full brothers	0.7	0.9	1.9	-1.1	1.3	1.1	1.1	-0.9	1.1	0.9	1.4	-1.1	-0.2	-0.5	1.1	-0.8	-1.1	0.7	0.8	-0.4	-0.0
Worry too long after embarrassment	0.6	1.0	4.8	1.7	-0.7	0.7	-1.0	0.9	-1.2	0.1	0.3	1.0	-0.0	0.8	0.6	-0.6	1.0	-0.5	-1.1	0.4	2.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	3.7	0.1	-0.8	-1.1	-0.8	0.2	-0.9	-0.6	-0.7	0.8	1.1	1.0	-0.9	0.9	-0.6	-0.1	-0.9	1.0	1.9
Wheeze or whistling in the chest in last year	0.5	0.9	4.3	1.4	-0.6	-0.6	-0.8	1.4	-0.4	-0.5	-1.1	0.9	0.3	1.4	-0.3	0.2	1.0	-0.2	-0.2	2.1	0.3
Number of children fathered	3.4	3.8	7.5	-0.8	2.3	2.7	2.3	-0.9	2.6	2.1	2.0	-2.2	-2.4	-0.8	2.4	-2.5	-0.8	0.5	2.4	-1.5	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.5	0.5	-0.8	-0.4	-0.9	0.9	-0.7	-0.9	-0.6	1.0	1.2	1.1	-1.1	1.1	0.6	-1.6	-0.7	1.5	-0.4
Age at first live birth	0.1	0.1	0.7	-0.1	-0.3	0.0	-0.3	0.0	-0.4	-0.5	-0.4	0.3	0.2	0.1	-0.2	0.4	-0.1	-0.8	0.1	0.1	-0.8
Pulse wave peak to peak time	0.8	0.9	2.9	-0.9	0.8	-0.2	1.3	-1.2	1.4	0.4	-0.7	-1.2	-1.0	-1.3	-0.3	0.2	-1.7	0.8	1.0	-0.4	0.7
Health satisfaction	1.3	1.7	5.4	2.3	-1.4	0.2	-1.4	2.3	-1.0	-0.9	-0.2	1.5	1.5	2.0	-0.4	-0.0	0.5	-2.0	-0.6	1.0	-0.8
Shortness of breath walking on level ground	0.6	0.7	2.3	-0.8	0.8	1.3	0.6	-0.1	0.6	0.9	1.5	-0.6	-0.3	0.1	0.9	-0.9	-0.3	0.3	1.5	-0.2	-1.2
Qualifications: College or University degree	0.3	0.9	4.2	0.9	-0.8	0.7	-0.7	0.9	-0.5	-1.1	-0.8	0.9	0.7	1.9	-0.4	0.8	0.1	-2.1	-0.7	1.2	0.2
Eye problems/disorders: None of the above	6.4	7.4	16.4	-0.1	-3.4	-2.7	-3.4	1.7	-4.1	-3.3	-2.7	3.2	2.8	1.4	-3.0	2.6	2.8	-2.7	-3.1	0.7	-1.8
Mouth/teeth dental problems: Loose teeth	0.3	0.3	1.0	-0.7	0.3	0.8	0.4	-0.3	0.5	0.3	0.8	-0.3	-0.3	0.4	0.6	-0.5	-0.3	-0.0	1.0	-0.0	-0.9
Emphysema/chronic bronchitis	1.3	1.4	3.0	-0.5	1.2	1.5	1.0	-0.4	1.1	1.5	1.0	-1.0	-1.1	-0.4	1.6	-1.7	-1.7	1.1	1.0	-1.7	0.7
Medication for pain relief, constipation, heartburn	1.3	2.2	3.4	-1.6	1.3	1.6	1.5	-1.8	1.4	1.4	1.1	-1.5	-1.6	-1.3	1.3	-1.2	-1.9	0.5	1.7	-1.8	1.6
Neck or shoulder pain in last month	0.2	0.3	0.8	-0.9	-0.3	-0.9	-0.3	0.2	-0.6	-0.4	-0.1	0.4	0.9	0.1	-0.7	0.7	-0.0	0.4	-0.0	0.8	-0.7
Medication: Blood pressure	2.3	4.1	8.3	1.5	-2.3	-2.9	-2.4	2.1	-2.2	-1.8	-2.0	2.3	2.3	1.6	-1.9	1.4	2.5	-0.8	-2.4	1.8	-1.0
Angina (self-reported)	0.9	1.2	3.6	0.9	-1.3	-0.7	-1.5	1.9	-1.4	-0.8	-0.1	1.4	0.7	0.8	-0.4	0.0	1.4	-1.2	-1.9	0.1	0.4
Migraine (self-reported)	0.2	0.2	2.3	-0.3	0.0	-0.0	0.1	-0.6	-0.1	0.1	0.5	-0.2	-0.1	-0.7	-0.2	0.0	-0.4	0.3	0.2	-0.3	-1.5
Medication: Ibuprofen	2.6	3.1	12.9	1.9	-1.2	-2.1	-1.1	1.1	-1.0	-1.9	-3.6	1.3	1.4	0.8	-2.2	2.2	0.9	-0.4	-1.7	2.4	1.4
Medication: Allopurinol	0.1	0.2	0.7	-0.7	0.3	0.2	0.2	-0.9	-0.1	0.1	-0.2	-0.3	-0.1	-0.5	0.0	0.3	-0.4	-0.4	-0.0	-0.5	0.6
Medication: Omeprazole	0.1	0.2	0.8	0.2	0.4	0.5	0.5	0.0	0.4	0.4	0.9	-0.3	-0.3	-0.2	0.4	-0.4	-0.1	-0.7	0.2	0.1	0.1
Medication: Seretide 50 evohaler	1.2	1.3	4.9	-1.1	1.3	2.2	1.3	-1.5	0.8	1.3	0.9	-1.1	-0.9	-0.9	1.1	-1.1	-1.2	0.6	1.1	-0.7	-0.1
Mean time to correctly identify matches	1.2	2.3	5.8	-0.2	-1.5	-1.5	-1.7	1.6	-1.5	-1.6	-1.7	1.7	2.4	1.2	-1.4	1.4	1.6	0.0	-2.1	1.7	-0.1
Heart disease (mother)	0.3	0.4	1.3	1.1	-0.5	-0.0	-0.5	0.8	-0.3	-0.3	-0.4	0.5	0.2	0.6	0.1	-0.1	1.1	-1.1	-0.6	-0.3	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.9	2.2	3.9	1.8	-1.5	-1.2	-1.3	1.3	-1.4	-2.0	-2.0	1.6	1.5	1.1	-1.7	1.8	1.2	-1.1	-1.5	1.6	0.3
Whole body fat mass	0.4	1.6	13.6	-1.3	0.9	0.7	0.8	-1.0	0.6	0.9	1.4	-0.9	-1.1	-0.8	0.9	-1.0	0.4	0.2	1.4	-0.3	-3.7
Leg fat mass (right)	0.4	1.5	11.2	-1.7	1.0	0.5	1.0	-1.2	0.6	1.0	1.4	-1.0	-1.1	-1.0	0.8	-0.9	0.2	-0.1	1.4	-0.2	-3.4
Arm predicted mass (right)	1.0	5.2	10.4	-1.9	2.6	2.7	2.5	-2.2	2.4	2.8	3.2	-2.5	-2.5	-1.7	2.6	-2.8	-1.5	0.8	2.4	-1.6	0.2
Pulse rate, automated reading	0.3	1.0	2.2	0.6	-0.8	-0.9	-0.7	0.8	-0.5	-1.1	-0.5	0.8	1.2	1.2	-1.2	1.2	1.2	0.1	0.5	1.5	-1.5
Alcohol intake frequency.	1.2	2.8	6.8	1.4	-1.9	-2.6	-1.9	1.8	-1.6	-1.9	-2.6	1.8	1.2	0.6	-1.9	1.5	0.5	0.6	-2.0	1.0	1.2
Comparative height size at age 10	2.0	10.8	15.8	-3.8	3.8	2.8	3.7	-3.9	3.4	3.7	3.1	-3.8	-3.4	-3.0	2.9	-2.5	-3.0	2.5	4.0	-2.3	2.6
Number of full sisters	0.3	0.3	1.1	0.5	0.2	-0.6	-0.0	0.3	0.2	0.8	1.1	-0.0	0.4	1.0	0.7	-1.1	-0.0	0.5	-0.4	0.3	-0.1
Suffer from ‘nerves’	0.4	0.7	3.2	0.8	-0.7	-0.2	-0.5	0.9	-0.3	-0.6	-1.8	0.6	0.4	0.5	-0.5	0.2	-1.4	-0.1	-0.5	0.4	1.8
Overall health rating	0.4	0.8	4.0	2.0	-0.2	0.7	-0.7	1.7	-0.4	0.1	0.4	0.7	0.2	1.7	0.7	-1.0	-0.1	-0.2	-0.5	0.7	0.6
Chest pain or discomfort	1.0	1.5	2.6	1.4	-1.5	-1.2	-1.4	1.2	-1.5	-1.3	-1.1	1.4	1.1	1.6	-1.3	1.1	0.8	-1.0	-1.2	0.5	-0.3
Had major operations	0.3	0.3	1.0	0.5	-0.5	-0.6	-0.4	0.6	-0.1	-0.3	-0.8	0.5	0.6	0.9	-0.4	0.3	0.9	-0.1	-0.5	1.0	-0.5
Age at last live birth	0.7	1.0	2.5	0.5	-1.0	-1.6	-1.1	0.8	-1.0	-1.0	-0.9	1.1	1.1	0.8	-1.0	1.1	0.8	-1.1	-1.0	1.6	-0.4
Family relationship satisfaction	6.8	8.3	17.0	3.9	-3.1	-2.5	-3.2	4.1	-2.2	-2.8	-2.9	3.3	3.5	3.6	-2.4	1.9	0.8	-1.3	-2.7	2.5	3.2
Leg pain on walking	0.3	0.3	1.8	-0.1	0.7	0.2	0.8	-0.5	0.8	0.6	0.4	-0.8	-0.4	-0.3	0.3	-0.5	-1.3	0.2	0.6	-0.5	-0.0
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.9	-1.7	0.3	-0.6	0.5	-1.2	-0.1	0.1	-0.5	-0.4	0.2	-1.5	-0.8	0.6	0.6	1.4	0.5	-0.1	-0.6
Commuting to job workplace: Car/motor vehicle	0.7	0.8	3.1	1.4	0.0	0.4	-0.5	1.6	0.0	0.4	0.3	0.2	0.2	0.7	1.4	-1.5	0.0	-0.6	-0.2	-0.3	-1.8
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	1.0	-0.0	-0.7	-0.5	-0.7	0.3	-0.8	-0.8	-0.3	0.7	0.6	0.5	-0.6	0.8	-0.1	-1.0	-0.5	0.1	0.2
Medication: Aspirin	0.1	0.1	0.4	0.3	0.3	0.1	0.4	0.4	0.6	-0.2	-0.2	-0.2	-0.1	0.2	-0.1	0.1	0.1	-0.1	0.1	0.2	-0.7
Supplements: Vitamin C	1.0	1.2	3.5	-1.9	0.7	0.2	0.4	-0.7	0.1	0.9	1.7	-0.6	0.3	-1.3	0.8	-0.7	-1.5	1.5	0.8	-1.4	-1.5
Knee pain experienced in last month	1.1	1.6	3.1	-0.1	1.4	1.5	1.4	-0.6	1.4	1.4	1.0	-1.3	-1.6	-1.0	1.2	-1.6	-1.8	1.2	1.4	-1.5	-0.1
Hypertension (Self-reported)	2.2	6.1	10.7	1.4	-2.9	-3.3	-3.1	2.8	-2.9	-2.3	-2.4	3.0	2.8	2.5	-2.2	1.8	2.3	-0.4	-3.0	2.5	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	2.1	0.2	0.4	0.3	0.5	-0.3	0.3	0.6	0.6	-0.5	-0.6	-0.5	0.4	-0.4	-1.4	0.4	0.4	-1.2	0.8
Illnesses of father: Heart disease	0.4	0.6	2.1	0.3	-1.0	-0.7	-1.0	0.7	-1.1	-0.0	-0.2	0.8	0.2	0.1	0.1	-0.4	1.5	-0.9	-1.0	-1.0	-0.3
Illnesses of siblings: Diabetes	0.3	0.4	1.1	-0.6	-0.0	0.3	-0.6	0.5	-0.6	-0.1	0.5	0.5	1.1	0.9	0.1	-0.2	0.9	-0.3	-0.6	0.9	-0.7
Smoking status: Previous	0.3	0.5	5.6	-1.0	0.4	0.2	0.1	-0.5	0.0	0.4	0.6	-0.2	-0.4	-0.1	0.3	-0.3	0.4	0.8	0.5	-0.1	-2.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	2.0	-0.5	-0.7	-1.4	-0.6	-0.4	-0.9	-0.4	-0.3	0.4	0.1	-0.3	-1.0	0.9	-0.1	-0.2	-1.2	0.3	0.6
Whole body fat-free mass	0.8	4.8	7.6	-1.5	2.5	2.7	2.5	-1.9	2.4	2.7	2.8	-2.4	-2.5	-1.6	2.4	-2.7	-1.6	0.7	2.4	-1.4	0.6
Leg fat-free mass (right)	1.3	6.7	10.5	-1.5	3.0	3.1	2.9	-2.3	2.9	3.2	3.1	-2.9	-3.2	-2.0	3.0	-3.2	-1.8	1.3	2.8	-1.8	0.4
Arm fat percentage (left)	0.3	1.0	13.8	-0.4	0.3	0.3	0.1	-0.1	-0.1	0.4	1.0	-0.2	-0.5	-0.4	0.6	-0.8	0.9	-0.4	0.6	-0.1	-3.7
Average weekly red wine intake	0.7	1.0	2.3	-0.5	1.2	1.4	1.5	-1.4	1.4	1.1	0.5	-1.3	-0.9	-0.6	0.7	-0.5	-0.9	0.5	1.5	-0.2	-0.0
Handedness (chirality/laterality): Left-handed	0.2	0.2	1.2	-0.1	0.4	0.1	0.6	-0.4	0.5	-0.1	-1.0	-0.4	-0.1	-0.3	-0.3	0.2	-0.4	0.7	-0.2	0.4	1.1
Mood swings	0.6	1.1	4.8	2.0	-0.4	-0.0	-0.7	1.6	-0.1	-0.2	-0.9	0.7	0.9	1.3	0.1	-0.4	-1.3	0.6	-0.6	1.4	2.2
Loneliness, isolation	0.5	0.7	4.8	0.8	-0.1	-0.8	-0.6	0.8	-0.5	0.7	-0.6	0.4	0.5	0.5	0.6	-1.2	-0.2	0.3	-0.9	-0.5	2.2
Long-standing illness, disability or infirmity	1.8	2.8	9.2	3.0	-1.6	-1.0	-1.9	3.0	-1.2	-1.0	-0.5	1.9	1.5	2.9	-0.5	-0.1	1.5	-0.5	-1.9	1.4	-0.3
Ever had bowel cancer screening	1.5	1.7	4.0	0.6	1.4	1.7	1.3	-0.6	1.5	1.6	1.0	-1.3	-1.8	-0.7	1.8	-2.0	-0.7	1.1	1.7	-0.7	-0.4
Diabetes diagnosed by doctor	0.4	0.7	2.7	-0.0	1.0	1.3	1.0	0.7	1.6	0.8	1.2	-0.7	-0.1	0.0	0.9	-0.9	-0.3	0.4	1.0	0.1	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.7	-0.2	-0.3	-1.0	-0.3	-0.3	-0.5	-0.5	-1.3	0.2	0.7	-0.3	-0.8	0.9	0.1	0.4	-0.6	0.3	-0.1
Friendships satisfaction	1.6	2.0	6.6	1.5	-1.1	-1.4	-1.0	1.5	-0.4	-1.2	-2.1	1.2	1.3	1.3	-1.5	1.4	0.1	-0.1	-1.0	2.6	2.2
Qualifications: nursing, teaching	0.8	1.3	3.4	0.3	1.1	1.9	1.3	0.0	1.8	0.9	1.3	-1.1	-1.1	-0.3	1.4	-1.3	-0.3	0.1	1.4	-1.1	-0.8
Commuting to job workplace: Walk	0.4	0.5	1.5	-0.8	0.5	0.4	0.6	-0.8	0.5	0.9	1.0	-0.6	-1.2	-0.6	0.3	-0.4	-0.6	0.2	0.9	-0.7	-0.0
Eye problems/disorders: Cataract	0.7	0.8	4.9	0.1	0.8	0.4	0.8	-0.3	1.1	0.9	0.7	-0.7	-0.9	-0.3	0.6	-0.5	-1.3	1.2	0.2	-0.1	2.2
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	2.5	0.1	-0.3	-1.0	-0.4	0.1	-0.2	-0.4	-1.6	0.4	-0.2	0.6	-0.6	0.6	-0.3	1.5	-1.0	1.6	1.2
Medication for cholesterol	0.4	0.6	1.5	0.3	0.7	0.1	1.0	-1.2	1.1	0.5	-0.6	-1.1	-1.2	-0.9	-0.2	0.2	-0.9	0.2	1.2	-0.6	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.3	-1.0	0.7	0.4	0.6	-1.1	0.1	0.6	0.2	-0.7	-0.9	-0.9	0.5	-0.3	0.2	-0.0	0.7	-0.1	-0.7
Back pain experienced in last month	0.4	0.6	1.1	0.8	-0.8	-0.1	-0.8	0.8	-1.0	-0.9	-0.7	1.0	0.7	0.8	-0.8	0.8	0.2	-0.8	-0.7	1.1	-0.4
Mineral and other dietary supplements	0.2	0.3	1.9	0.4	-0.2	0.0	-0.1	0.3	0.1	-0.3	-0.7	0.2	-0.3	0.2	-0.6	0.5	0.6	-1.4	-0.4	0.8	0.8
Breast cancer (self-reported)	2.7	3.3	5.2	-1.2	2.0	2.0	2.0	-1.0	2.3	1.7	2.1	-2.0	-1.9	-1.8	1.8	-1.8	-2.0	0.9	1.6	-2.2	1.4
Asthma (self-reported)	1.9	3.8	6.9	1.9	-2.1	-1.0	-2.5	2.4	-2.4	-1.6	-0.6	2.4	2.3	2.5	-1.1	0.8	2.6	-2.0	-2.3	1.9	-0.7
Osteoporosis (self-reported)	0.2	0.3	0.8	-0.3	-0.8	-0.9	-0.7	0.3	-0.8	-0.4	-0.0	0.6	0.6	-0.1	-0.7	0.7	0.6	-0.0	-0.5	-0.3	-0.3
Osteoarthritis (self-reported)	2.2	2.8	5.7	-0.7	1.9	1.9	1.5	-1.6	1.1	2.2	2.4	-1.6	-1.5	-1.0	1.8	-1.9	-1.7	1.5	1.3	-0.9	2.3
Medication: Aspirin	0.1	0.1	0.5	0.6	0.2	-0.0	0.3	0.7	0.6	-0.2	-0.3	-0.1	-0.1	0.4	-0.1	0.1	-0.2	-0.1	-0.0	0.4	-0.6
Medication: Gliclazide	0.7	0.7	3.8	1.4	-0.5	-0.5	-0.5	1.3	-0.0	-0.3	-0.1	0.6	0.6	1.2	-0.3	0.1	0.5	0.2	-0.7	1.4	1.9
Illnesses of father: None of the above (group 1)	1.1	1.4	4.5	-1.4	1.2	0.2	1.4	-1.2	1.3	0.7	0.0	-1.3	-0.5	-1.2	0.3	-0.3	-2.1	2.1	1.2	-0.6	-1.0
Smoking status: Current	0.9	1.4	6.1	0.7	1.1	1.3	0.9	0.6	1.6	1.4	0.1	-0.8	-0.5	0.1	1.6	-2.0	-1.4	1.0	0.8	-0.1	2.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	2.1	1.4	-0.9	-0.3	-1.1	0.9	-1.0	-1.2	-1.1	1.1	1.3	0.6	-0.6	0.7	0.7	-0.1	-1.2	1.4	-0.4
Whole body water mass	0.9	4.9	8.1	-1.6	2.5	2.8	2.5	-1.9	2.4	2.8	2.9	-2.5	-2.6	-1.6	2.5	-2.8	-1.6	0.6	2.4	-1.4	0.5
Leg predicted mass (right)	1.2	6.5	10.2	-1.5	2.9	3.1	2.9	-2.2	2.9	3.2	3.0	-2.9	-3.2	-2.0	2.9	-3.1	-1.8	1.3	2.8	-1.8	0.4
Arm fat mass (left)	0.3	1.1	9.5	-0.7	0.7	0.8	0.6	-0.4	0.4	0.9	1.6	-0.6	-0.9	-0.4	1.1	-1.3	0.5	-0.4	0.9	-0.2	-3.1
Number of self-reported non-cancer illnesses	0.7	1.2	2.8	0.9	-1.4	-0.5	-1.6	1.2	-1.7	-0.6	-0.3	1.6	1.4	1.4	-0.6	0.4	1.4	-0.3	-1.2	1.2	0.2
Average weekly champagne plus white wine intake	1.2	1.7	3.2	1.0	1.5	1.2	1.3	-1.2	1.6	1.5	0.7	-1.5	-1.5	-1.0	1.6	-1.8	-1.3	-0.6	0.8	-1.6	0.8
Miserableness	0.4	0.8	5.4	1.7	-0.3	-0.7	-0.6	1.2	-0.1	0.1	-1.1	0.4	-0.2	0.8	0.2	-0.6	-0.0	0.7	-0.6	0.2	2.3
Guilty feelings	0.7	1.0	2.7	1.1	-0.9	-0.5	-1.2	1.5	-0.9	-0.6	-0.7	1.2	1.6	1.3	-0.4	0.1	0.7	-0.4	-0.9	1.6	0.6
Wears glasses or contact lenses	0.8	0.9	3.5	-1.9	0.5	0.4	0.5	-1.2	-0.1	0.7	1.9	-0.5	-0.3	-1.1	0.5	-0.4	-0.2	0.8	0.9	-1.3	-0.9
Ever taken oral contraceptive pill	3.2	3.6	5.5	1.3	-2.2	-1.6	-2.1	2.3	-1.8	-2.3	-2.0	2.2	2.3	1.8	-1.7	1.5	1.4	-1.6	-2.2	1.1	-1.9
Hearing aid user	1.0	1.1	1.9	-1.2	1.0	0.7	0.9	-1.1	0.8	1.3	1.2	-1.1	-0.9	-1.4	1.1	-1.0	-1.1	0.5	1.1	-1.2	-0.7
Mother’s age at death	0.7	0.9	3.1	0.2	-0.8	-0.6	-0.8	0.5	-0.7	-0.8	-1.2	0.8	0.9	0.8	-0.9	0.8	1.6	0.5	-0.3	1.6	-1.8
Financial situation satisfaction	5.2	6.5	9.6	2.3	-2.8	-2.9	-3.0	3.1	-2.9	-2.5	-2.0	3.1	3.1	2.8	-2.5	2.0	1.8	-0.8	-2.9	2.9	-0.0
Tinnitus: Yes, now most or all of the time	1.7	2.0	6.1	-1.7	1.1	1.3	0.7	-1.3	0.4	1.7	2.5	-1.0	-1.3	-1.0	1.9	-1.9	-0.8	0.5	1.2	-2.2	-0.5
Commuting to job workplace: Public transport	0.5	0.6	5.7	0.7	0.4	-0.3	0.6	-0.5	0.6	0.3	0.2	-0.5	-0.6	-0.6	0.0	0.1	-0.6	1.2	-0.1	-0.3	2.4
Eye problems/disorders: Glaucoma	3.9	4.6	13.0	0.7	2.4	2.5	2.2	-0.7	2.8	2.7	3.6	-2.1	-1.6	-0.2	2.8	-2.9	-0.8	1.1	3.1	-1.2	-0.6
Medication: Blood pressure	0.8	1.6	4.0	-0.7	-1.5	-1.3	-1.6	1.1	-2.0	-1.0	-0.5	1.6	1.5	1.2	-0.8	0.7	1.2	-0.2	-2.0	0.9	0.8
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.4	-0.1	0.6	0.3	0.4	0.4	0.7	1.0	0.4	-0.4	-0.1	-0.3	0.8	-1.1	0.1	1.2	0.5	-0.4	-1.2
Supplements: Fish oil (including cod liver oil)	0.3	0.3	1.7	-0.2	0.3	0.1	0.0	0.1	-0.0	0.4	0.6	-0.2	-0.1	-0.4	0.8	-0.9	-0.4	1.2	0.5	-1.3	-0.4
High cholesterol (Self-reported)	0.1	0.2	0.8	0.9	-0.1	-0.2	-0.2	0.1	-0.4	0.2	0.0	0.3	-0.2	-0.1	-0.0	0.1	0.1	0.9	0.3	0.5	-0.9
Medication: Bendroflumethiazide	2.3	3.5	6.9	1.1	-2.3	-1.8	-2.5	2.0	-2.6	-2.0	-0.9	2.3	2.1	1.4	-1.5	1.2	2.2	-2.1	-2.6	0.6	-0.3
Medication: Paracetamol	1.7	2.7	4.9	0.8	-1.8	-2.2	-2.0	2.0	-2.0	-1.8	-1.1	2.0	1.9	1.4	-1.5	1.3	1.4	-0.7	-1.9	1.5	-1.2
Medication: Lisinopril	1.7	2.2	4.4	-0.9	-1.7	-2.1	-1.6	0.4	-1.9	-1.6	-0.6	1.5	2.1	0.3	-1.8	1.9	1.0	-1.6	-1.9	1.0	-0.7
Medication: Atorvastatin	1.7	2.1	7.8	1.8	-1.4	-1.0	-1.7	2.0	-1.6	-0.9	-0.2	1.6	0.9	1.7	-0.4	0.0	2.8	-1.0	-1.8	0.3	-1.7
Illnesses of father: High blood pressure	0.7	0.8	5.2	0.5	-0.8	0.4	-1.0	0.6	-1.2	-0.6	0.5	0.9	0.7	0.7	-0.3	0.2	0.3	-2.3	-1.0	0.5	1.2
Alcohol drinker status: Never	0.6	0.7	4.2	-0.7	0.2	-1.0	-0.0	-0.3	0.0	0.2	-0.1	-0.2	-0.1	-1.2	0.1	-0.3	-1.3	2.1	-0.5	-1.0	1.6
Ever smoked	0.3	0.4	1.1	-0.5	1.0	0.5	0.7	-0.5	0.9	0.9	-0.4	-0.6	-0.4	0.5	0.6	-0.7	-0.3	0.5	0.3	1.1	-1.0
Basal metabolic rate	0.7	4.2	7.5	-1.5	2.3	2.5	2.3	-1.8	2.2	2.6	2.7	-2.3	-2.5	-1.4	2.3	-2.6	-1.2	0.5	2.3	-1.2	-0.1
Leg fat percentage (left)	0.4	1.6	15.9	-2.2	0.7	0.1	0.7	-1.3	0.0	0.5	1.1	-0.7	-0.6	-1.2	0.3	-0.3	0.3	-0.2	1.1	-0.2	-4.0
Arm fat-free mass (left)	0.6	3.0	7.3	-1.7	1.9	2.1	1.8	-1.5	1.7	2.1	2.7	-1.8	-1.8	-1.0	1.9	-2.2	-1.0	0.2	1.9	-1.1	-0.4
Number of operations (self-reported)	0.2	0.3	1.7	0.6	-0.0	0.0	-0.0	0.6	0.2	0.0	0.0	0.1	0.1	1.2	0.2	-0.2	0.9	-1.3	-0.2	1.1	0.2
Average weekly beer plus cider intake	0.4	0.5	1.5	-0.3	-0.4	-1.0	-0.7	0.4	-1.0	0.1	0.9	0.4	0.2	0.7	0.4	-0.6	1.0	-0.9	-1.2	-0.5	1.1
Irritability	0.5	0.8	3.6	-0.3	-0.6	-0.9	-0.5	-0.0	-0.8	-0.9	-1.9	0.6	1.1	-0.2	-1.2	1.2	-0.4	-0.1	-0.7	1.5	0.7
Risk taking	0.2	0.2	0.6	-0.4	-0.3	-0.6	-0.6	0.2	-0.5	-0.1	0.1	0.4	0.6	0.7	-0.0	-0.0	0.7	-0.7	-0.7	0.4	0.6
Ever had prostate specific antigen (PSA) test	2.0	2.3	4.3	-0.6	1.6	2.1	1.4	-1.3	1.2	1.7	1.6	-1.5	-1.4	-1.8	1.8	-1.9	-1.2	0.6	2.0	-1.8	0.0
Fractured/broken bones in last 5 years	0.1	0.1	0.5	0.3	-0.7	-0.2	-0.4	0.4	-0.4	-0.1	0.1	0.5	-0.3	0.2	-0.3	0.1	0.6	-0.3	-0.4	-0.1	0.2
Age started oral contraceptive pill	0.5	0.6	6.2	-0.6	-0.6	-0.3	-0.7	0.7	-0.5	-0.6	0.5	0.6	0.4	0.8	-0.1	0.3	0.9	-0.2	0.1	-0.0	-2.5
Diastolic blood pressure, automated reading	0.0	0.1	0.5	0.1	0.0	-0.5	-0.1	-0.1	-0.0	0.3	0.6	-0.1	-0.2	0.7	0.3	-0.1	0.6	0.4	0.2	0.5	-0.2
Ever depressed for a whole week	1.9	2.3	6.4	-2.1	1.6	1.4	1.4	-1.5	1.0	1.4	1.2	-1.5	-0.8	-1.6	1.4	-1.4	-1.7	0.8	1.0	-1.9	2.5
Unable to work because of sickness or disability	0.1	0.1	0.9	0.9	0.2	-0.4	-0.0	0.6	0.0	0.3	-0.3	0.0	0.4	0.1	0.3	-0.5	-0.2	0.3	-0.1	0.2	0.2
Commuting to job workplace: Cycle	0.5	0.6	2.6	0.6	-0.8	-0.5	-0.5	0.0	-0.7	-0.7	-1.0	0.5	-0.0	0.2	-0.8	0.8	1.6	-1.4	-1.1	0.3	0.3
Myopia	0.2	0.3	0.9	1.0	-0.4	-0.6	-0.2	0.7	0.2	-0.7	-0.9	0.3	0.0	0.4	-0.8	0.7	-0.1	0.1	-0.3	0.7	-0.0
Vascular/heart problems diagnosed by doctor	3.0	8.2	13.5	-1.6	3.4	3.7	3.6	-3.3	3.4	2.6	2.6	-3.5	-3.0	-2.8	2.5	-2.0	-3.0	0.6	3.7	-2.6	-0.3
Cholesterol lowering medication	0.3	0.4	2.2	0.7	0.0	0.7	-0.4	0.9	-0.2	0.3	1.5	0.3	-0.1	0.5	1.1	-0.9	0.9	-0.4	-0.2	-0.2	0.4
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.3	0.0	0.8	0.3	0.9	-0.4	0.8	0.9	1.1	-0.8	-0.9	-0.6	0.8	-0.8	-0.3	-0.2	0.5	-0.7	-0.2
Pain experienced in last month	0.1	0.2	0.8	-0.0	-0.4	-0.3	-0.3	0.3	-0.1	-0.7	-0.2	0.4	0.2	0.6	-0.6	0.7	0.9	-0.2	-0.2	0.6	-0.1
Supplements: Calcium	1.0	1.1	4.7	-1.9	0.5	0.1	0.9	-1.3	0.7	0.5	0.6	-0.9	-1.1	-1.4	0.4	-0.2	-1.0	0.6	0.4	-1.4	-2.2
Basal cell carcinoma (self-reported)	0.9	1.1	2.0	1.4	-1.0	-1.4	-1.4	1.2	-0.9	-0.7	-0.4	1.1	1.0	1.2	-0.7	0.3	0.3	-0.4	-1.3	1.4	1.2
Heart attack/myocardial infarction (self-reported)	0.7	0.9	2.5	1.4	-0.8	-0.6	-1.1	1.3	-0.9	-1.0	-1.1	1.1	0.6	0.9	-0.3	0.6	0.5	-0.5	-1.6	1.2	0.8
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	5.5	-0.2	1.1	1.0	1.1	-0.4	1.1	1.0	0.9	-1.0	-1.0	-0.8	1.1	-1.0	-2.3	1.1	0.9	-0.8	2.2
Heart disease (siblings)	0.2	0.3	1.3	0.0	-0.2	-0.6	-0.4	0.3	-0.4	0.4	0.8	0.2	-0.5	-0.2	0.4	-0.6	-0.0	-0.2	-0.7	-0.9	1.1
Alcohol drinker status: Previous	0.3	0.4	1.8	0.8	-0.7	-1.0	-0.7	0.4	-0.5	-0.5	-1.3	0.6	0.5	-0.2	-0.5	0.4	0.7	0.3	-0.5	0.5	-0.0
Pack years of smoking	0.3	0.4	0.8	-0.7	0.5	0.2	0.6	-0.8	0.4	0.1	-0.4	-0.6	-0.8	-0.7	0.4	-0.0	-0.7	0.7	0.8	-0.9	-0.9
Impedance of whole body	0.5	2.7	5.4	0.7	-1.9	-2.3	-1.9	1.4	-1.8	-2.1	-2.2	1.9	1.8	1.1	-2.0	2.2	0.8	-0.2	-1.8	1.2	-0.2
Leg fat mass (left)	0.6	2.4	10.9	-2.1	1.4	0.9	1.4	-1.7	1.0	1.4	1.8	-1.4	-1.5	-1.5	1.2	-1.3	-0.3	0.3	1.8	-0.7	-3.3
Arm predicted mass (left)	0.5	2.3	5.9	-1.5	1.7	1.9	1.7	-1.4	1.5	1.8	2.4	-1.6	-1.7	-0.7	1.7	-1.9	-0.8	-0.2	1.6	-0.8	-0.4