[Hub]/) : Traits : Crohns Disease (2017) : ← →

chr10:63,856,856-65,264,300

Best TWAS P=1.72e-17 · Best GWAS P=5.47e-29 conditioned to 3.93e-14

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Muscle Skeletal	ADO	0.15	0.16	lasso	8	0.16	1.1e-15	8.2	8.5	1.7e-17	0.61	1.00	0.00	TRUE
4	GTEx	Testis	ADO	0.21	0.23	lasso	7	0.22	6.6e-10	8.2	-8.2	1.9e-16	-0.60	0.88	0.12	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ADO	0.04	0.01	blup	465	0.02	1.8e-03	7.4	7.9	3.0e-15	0.55	0.02	0.82	FALSE
7	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADO	0.07	0.06	blup	53	0.05	2.5e-06	7.4	7.4	1.1e-13	0.54	0.00	1.00	FALSE
8	The Cancer Genome Atlas	Skin Cutaneous Melanoma	EGR2	0.12	0.10	blup	56	0.10	1.4e-03	5.7	7.1	1.2e-12	0.38	0.03	0.13	FALSE
5	The Cancer Genome Atlas	Breast Invasive Carcinoma	ADO	0.03	0.02	blup	53	0.03	1.8e-06	5.5	6.7	1.9e-11	0.51	0.33	0.67	FALSE
3	GTEx	Muscle Skeletal	RP11-436D10.3	0.08	0.04	enet	13	0.06	3.2e-06	-4.7	6.1	1.2e-09	0.50	0.90	0.05	FALSE
6	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ADO	0.10	0.03	enet	6	0.06	4.6e-07	7.4	5.7	1.2e-08	0.52	0.02	0.97	FALSE