[Hub]/) : Traits : Crohns Disease (2017) : ← →

chr10:74,714,177-76,323,150

Best TWAS P=1.77e-11 · Best GWAS P=6.03e-11 conditioned to 0.00342

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Brain Cerebellar Hemisphere	RP11-464F9.22	0.22	0.04	lasso	4	0.07	7.3e-03	-2.7	6.7	1.8e-11	-0.64	0.03	0.46	TRUE
8	GTEx	Breast Mammary Tissue (Female)	FUT11	0.11	-0.01	enet	8	0.00	2.5e-01	-6.5	6.7	2.1e-11	-0.92	0.02	0.73	FALSE
10	GTEx	Cells Transformed fibroblasts	SEC24C	0.06	0.01	lasso	5	0.01	3.9e-02	-5.6	-6.5	7.2e-11	0.84	0.04	0.82	FALSE
4	GTEx	Artery Aorta	FUT11	0.07	0.04	enet	16	0.04	2.9e-03	-5.9	6.5	1.0e-10	-0.81	0.02	0.95	FALSE
9	GTEx	Breast Mammary Tissue (Female)	ZSWIM8	0.30	0.06	lasso	5	0.04	2.5e-02	-5.6	-6.1	8.9e-10	0.70	0.04	0.54	FALSE
7	GTEx	Breast Mammary Tissue	FUT11	0.07	0.08	lasso	5	0.03	1.1e-02	-5.9	6.1	1.1e-09	-0.89	0.03	0.81	FALSE
15	GTEx	Muscle Skeletal	FUT11	0.10	0.10	enet	16	0.11	8.5e-11	-6.5	6.1	1.3e-09	-0.95	0.01	0.99	FALSE
2	GTEx	Adipose Subcutaneous	SEC24C	0.04	0.02	lasso	2	0.00	1.3e-01	-5.9	-6.0	1.6e-09	0.86	0.06	0.78	FALSE
22	METSIM	Adipose	CAMK2G	0.11	0.05	bslmm	247	0.05	2.0e-08	-5.9	5.9	3.0e-09	-0.81	0.04	0.96	FALSE
24	YFS	Blood	CAMK2G	0.01	0.00	blup	239	0.00	5.7e-02	-5.8	5.9	3.0e-09	-0.60	0.06	0.79	FALSE
30	The Cancer Genome Atlas	Brain Lower Grade Glioma	FUT11	0.05	0.04	lasso	2	0.04	3.3e-05	-5.7	5.9	3.2e-09	-0.78	0.00	0.99	FALSE
13	GTEx	Esophagus Mucosa	SEC24C	0.11	0.08	lasso	4	0.10	6.7e-07	-5.6	5.9	4.2e-09	-0.84	0.07	0.93	FALSE
31	The Cancer Genome Atlas	Lung Adenocarcinoma	BMS1P4	0.03	0.01	blup	23	0.01	1.1e-02	-5.7	5.8	6.3e-09	-0.75	0.00	0.81	FALSE
5	GTEx	Artery Tibial	DUSP8P5	0.09	0.03	enet	8	0.03	2.0e-03	-5.4	-5.8	6.5e-09	0.64	0.24	0.44	FALSE
3	GTEx	Adrenal Gland	AGAP5	0.22	0.05	lasso	4	0.04	1.8e-02	-6.4	-5.8	7.3e-09	0.89	0.02	0.83	FALSE
20	GTEx	Skin Not Sun Exposed Suprapubic	AGAP5	0.11	0.07	lasso	5	0.07	1.8e-04	-5.6	-5.6	2.1e-08	0.75	0.12	0.76	FALSE
19	GTEx	Prostate	RP11-574K11.5	0.29	0.02	enet	43	0.00	2.4e-01	-5.5	5.6	2.3e-08	-0.21	0.04	0.13	FALSE
1	CommonMind	Brain Pre-frontal Cortex	BMS1P4	0.17	0.20	lasso	1	0.19	1.2e-22	-5.6	5.6	2.6e-08	-0.76	0.54	0.46	FALSE
27	The Cancer Genome Atlas	Breast Invasive Carcinoma	BMS1P4	0.03	0.03	lasso	4	0.03	2.2e-06	-5.6	5.6	2.8e-08	-0.75	0.00	1.00	FALSE
21	GTEx	Whole Blood	FUT11	0.05	0.01	lasso	5	0.01	6.3e-02	-6.3	5.5	3.6e-08	-0.86	0.03	0.88	FALSE
25	YFS	Blood	NDST2	0.10	0.09	lasso	14	0.10	5.0e-30	-5.6	5.5	3.6e-08	-0.53	0.82	0.18	FALSE
12	GTEx	Esophagus Mucosa	CAMK2G	0.10	0.04	lasso	3	0.06	4.0e-05	-5.5	-5.5	3.8e-08	0.64	0.31	0.38	FALSE
26	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	BMS1P4	0.05	0.01	enet	4	0.02	8.4e-03	-5.2	5.5	4.8e-08	-0.50	0.02	0.62	FALSE
18	GTEx	Ovary	RP11-574K11.29	0.20	0.16	enet	10	0.28	1.6e-07	-5.6	5.4	5.3e-08	-0.73	0.07	0.42	FALSE
16	GTEx	Nerve Tibial	AGAP5	0.08	0.01	lasso	8	0.02	2.0e-02	-5.8	-5.4	6.5e-08	0.75	0.18	0.69	FALSE
23	ROSMAP	Brain Pre-frontal Cortex	FUT11	0.09	0.08	lasso	6	0.07	7.6e-10	-5.7	5.4	8.5e-08	-0.78	0.46	0.54	FALSE
17	GTEx	Nerve Tibial	FUT11	0.19	0.16	enet	28	0.18	1.0e-12	-5.9	5.4	8.7e-08	-0.81	0.21	0.79	FALSE
14	GTEx	Esophagus Mucosa	FUT11	0.15	0.21	lasso	5	0.21	2.5e-14	-5.6	5.3	8.9e-08	-0.76	0.53	0.47	FALSE
28	The Cancer Genome Atlas	Breast Invasive Carcinoma	C10orf55	0.01	0.01	blup	32	0.01	5.0e-03	-5.6	5.3	1.2e-07	-0.93	0.01	0.75	FALSE
29	The Cancer Genome Atlas	Breast Invasive Carcinoma	CHCHD1	0.02	0.01	lasso	2	0.01	2.5e-03	-5.2	-5.2	1.8e-07	0.54	0.03	0.77	FALSE
11	GTEx	Cells Transformed fibroblasts	FUT11	0.13	0.08	lasso	4	0.08	1.5e-06	-5.8	5.2	1.9e-07	-0.77	0.11	0.89	FALSE