Best TWAS P=5.33e-15 · Best GWAS P=8.9e-15 conditioned to 3.05e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TSPAN14 | 0.15 | 0.13 | enet | 17 | 0.15 | 3.2e-18 | -6.2 | 6.2 | 4.7e-10 | 0.04 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | TSPAN14 | 0.13 | 0.04 | lasso | 4 | 0.06 | 1.9e-05 | -6.3 | -6.0 | 2.4e-09 | -0.05 | 0.00 | 1.00 | FALSE |
| 3 | YFS | Blood | TSPAN14 | 0.31 | 0.34 | lasso | 7 | 0.38 | 8.3e-132 | -6.3 | -6.3 | 2.4e-10 | -0.05 | 0.00 | 1.00 | TRUE |
| 4 | YFS | Blood | ZMIZ1 | 0.02 | 0.02 | lasso | 2 | 0.02 | 4.8e-06 | -7.7 | -7.8 | 5.3e-15 | 0.61 | 0.01 | 0.99 | TRUE |