[Hub]/) : Traits : Crohns Disease (2017) : ← →

chr17:39,328,012-41,699,963

Best TWAS P=3.77e-12 · Best GWAS P=1.79e-12 conditioned to 0.0199

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	NAGLU	0.04	0.03	bslmm	246	0.01	6.5e-02	-5.7	6.9	3.8e-12	-0.32	0.07	0.04	TRUE
18	METSIM	Adipose	PTRF	0.03	0.02	lasso	3	0.01	3.3e-03	-6.4	6.2	6.5e-10	-0.83	0.02	0.98	TRUE
20	YFS	Blood	FAM134C	0.03	0.01	enet	12	0.01	1.2e-05	-2.7	6.0	1.9e-09	-0.30	0.34	0.04	FALSE
2	GTEx	Adipose Subcutaneous	NAGLU	0.31	0.12	lasso	3	0.11	3.7e-09	-5.8	6.0	2.5e-09	-0.39	0.91	0.09	FALSE
19	NTR	Blood	FAM134C	0.01	0.00	bslmm	265	0.00	8.2e-03	-6.2	5.9	4.6e-09	-0.59	0.04	0.23	FALSE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	NAGLU	0.19	0.03	lasso	1	0.03	9.1e-07	-5.8	5.8	5.9e-09	-0.39	0.00	1.00	FALSE
23	The Cancer Genome Atlas	Thyroid Carcinoma	NAGLU	0.59	0.09	lasso	2	0.09	6.2e-09	-5.8	5.8	5.9e-09	-0.39	0.00	1.00	FALSE
3	GTEx	Adipose Subcutaneous	RP11-400F19.8	0.13	0.08	lasso	2	0.07	1.7e-06	-5.8	5.8	6.0e-09	-0.39	0.84	0.08	FALSE
4	GTEx	Artery Aorta	NAGLU	0.22	0.10	enet	23	0.11	1.1e-06	-5.1	5.7	8.9e-09	-0.47	0.83	0.06	FALSE
8	GTEx	Brain Caudate basal ganglia	NAGLU	0.15	0.19	lasso	2	0.15	5.0e-05	-5.7	5.7	1.2e-08	-0.39	0.16	0.12	FALSE
9	GTEx	Cells Transformed fibroblasts	NAGLU	0.28	0.22	lasso	4	0.22	7.5e-17	-5.7	5.7	1.4e-08	-0.41	0.93	0.07	FALSE
10	GTEx	Cells Transformed fibroblasts	RP11-400F19.8	0.20	0.16	lasso	3	0.15	1.4e-11	-5.7	5.6	1.7e-08	-0.39	0.93	0.07	FALSE
5	GTEx	Artery Aorta	RP11-400F19.8	0.21	0.08	enet	19	0.07	7.0e-05	-5.1	5.6	2.0e-08	-0.46	0.47	0.04	FALSE
14	GTEx	Nerve Tibial	NAGLU	0.15	0.10	lasso	4	0.08	2.3e-06	-5.7	5.6	2.0e-08	-0.42	0.91	0.07	FALSE
7	GTEx	Artery Tibial	RP11-400F19.8	0.16	0.11	lasso	5	0.11	8.1e-09	-5.7	5.6	2.1e-08	-0.38	0.91	0.08	FALSE
6	GTEx	Artery Tibial	NAGLU	0.18	0.12	lasso	4	0.13	3.3e-10	-5.8	5.5	3.1e-08	-0.37	0.91	0.08	FALSE
11	GTEx	Colon Sigmoid	AOC3	0.26	0.03	lasso	11	0.02	5.5e-02	-2.7	5.4	6.5e-08	-0.45	0.04	0.28	FALSE
16	GTEx	Vagina	ACLY	0.48	0.08	enet	71	0.22	7.5e-06	-6.2	-5.4	7.0e-08	0.52	0.14	0.30	FALSE
17	METSIM	Adipose	NAGLU	0.05	0.05	lasso	4	0.05	4.5e-08	-5.7	5.3	8.9e-08	-0.36	0.93	0.06	FALSE
13	GTEx	Muscle Skeletal	TUBG2	0.12	0.09	lasso	8	0.10	1.1e-09	-3.8	5.3	9.6e-08	-0.46	0.98	0.02	FALSE
15	GTEx	Nerve Tibial	RP11-400F19.8	0.10	0.03	lasso	3	0.02	8.2e-03	-5.1	5.2	2.4e-07	-0.50	0.18	0.06	FALSE
12	GTEx	Esophagus Muscularis	NAGLU	0.29	0.09	lasso	5	0.07	6.2e-05	-5.1	5.1	2.8e-07	-0.44	0.71	0.05	FALSE
21	YFS	Blood	NAGLU	0.04	0.02	lasso	4	0.03	1.3e-09	-5.7	5.1	2.9e-07	-0.37	0.93	0.07	FALSE