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Depressed Affect (Nagel 2018)
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chr2:147,993,969-149,475,737
Best TWAS P=7.13e-08 · Best GWAS P=9.48e-10 conditioned to 0.00245
148M
148.2M
148.4M
148.6M
148.8M
149M
149.2M
149.4M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Brain Lower Grade Glioma
ORC4L
0.06
0.01
blup
37
0.03
0.00016
5.3
5.4
7.1e-08
0.79
0.01
0.96
TRUE
1
GTEx
Breast Mammary Tissue (Female)
ORC4
0.12
0.00
lasso
4
0.00
0.23200
5.4
-5.2
1.6e-07
-0.89
0.03
0.34
FALSE