Best TWAS P=7.13e-08 · Best GWAS P=9.48e-10 conditioned to 0.00245
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue (Female) | ORC4 | 0.12 | 0.00 | lasso | 4 | 0.00 | 0.23200 | 5.4 | -5.2 | 1.6e-07 | -0.89 | 0.03 | 0.34 | FALSE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ORC4L | 0.06 | 0.01 | blup | 37 | 0.03 | 0.00016 | 5.3 | 5.4 | 7.1e-08 | 0.79 | 0.01 | 0.96 | TRUE |