[Hub]/) : Traits : Blood Eosinophil Count : →

chr1:1,287,040-4,263,997

Best TWAS P=2.92e-15 · Best GWAS P=8.2e-15 conditioned to 0.299

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Brain Cerebellum	TNFRSF14	0.17	0.07	enet	6	0.10	7.6e-04	-7.4	-7.9	2.9e-15	0.91	0.01	0.94	TRUE
2	GTEx	Brain Cerebellum	RP3-395M20.8	0.19	0.05	enet	8	0.06	5.9e-03	-6.1	-7.7	1.0e-14	0.85	0.02	0.90	FALSE
3	GTEx	Brain Cortex	PLCH2	0.27	0.03	enet	17	0.04	2.6e-02	-6.1	-5.7	1.2e-08	0.27	0.05	0.06	FALSE
4	GTEx	Esophagus Mucosa	FAM213B	0.08	0.02	lasso	3	0.01	3.9e-02	-6.1	-6.1	9.8e-10	0.64	0.01	0.91	FALSE
5	GTEx	Esophagus Muscularis	RP3-395M20.12	0.08	0.06	enet	6	0.06	2.3e-04	-7.4	7.2	5.4e-13	-0.84	0.01	0.98	FALSE
6	GTEx	Ovary	PRKCZ	0.36	-0.01	lasso	5	0.00	2.5e-01	-6.1	-5.9	4.7e-09	0.37	0.06	0.19	FALSE
7	GTEx	Pancreas	TNFRSF14	0.13	0.04	enet	8	0.04	1.0e-02	-7.4	-6.2	5.0e-10	0.89	0.02	0.97	FALSE
8	GTEx	Prostate	RP3-395M20.12	0.25	0.25	lasso	2	0.15	1.5e-04	-6.0	5.9	2.9e-09	-0.52	0.34	0.33	FALSE
9	GTEx	Skin Sun Exposed Lower leg	WRAP73	0.30	0.07	enet	26	0.19	1.1e-15	-3.2	-5.1	2.8e-07	0.00	0.06	0.83	FALSE
10	GTEx	Whole Blood	FAM213B	0.06	0.00	lasso	3	0.00	6.5e-01	4.0	6.0	2.5e-09	-0.81	0.02	0.78	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	TTC34	0.09	0.03	enet	21	0.07	5.7e-09	-4.7	-5.3	1.0e-07	0.75	0.15	0.85	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	RP3-395M20.9	0.06	0.01	blup	367	0.04	5.7e-06	-4.8	-6.1	1.4e-09	0.75	0.06	0.94	FALSE
13	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	WDR8	0.07	0.09	lasso	3	0.08	2.6e-07	5.1	-5.2	2.3e-07	0.00	0.00	1.00	FALSE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	LOC115110	0.01	0.01	enet	14	0.01	5.2e-04	-7.6	6.2	8.0e-10	-0.71	0.01	0.95	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	MMEL1	0.02	0.02	blup	38	0.03	3.3e-06	-4.2	6.4	1.3e-10	-0.87	0.18	0.82	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	WDR8	0.06	0.03	enet	14	0.04	2.6e-09	5.1	-5.8	8.9e-09	0.02	0.00	1.00	TRUE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	WDR8	0.15	0.11	enet	18	0.16	6.0e-18	-3.2	-5.2	2.0e-07	0.00	0.01	0.97	FALSE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	HES5	0.03	0.02	blup	39	0.01	1.0e-02	-6.1	-5.3	1.4e-07	0.42	0.14	0.04	FALSE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	MMEL1	0.05	0.03	blup	39	0.05	1.6e-06	-7.5	6.2	6.7e-10	-0.85	0.02	0.98	FALSE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	LOC115110	0.03	0.00	blup	50	0.01	1.7e-02	-7.8	7.6	4.0e-14	-0.87	0.01	0.64	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	MMEL1	0.10	0.12	enet	22	0.15	8.5e-16	-4.7	6.2	5.0e-10	-0.81	0.19	0.81	FALSE
22	The Cancer Genome Atlas	Testicular Germ Cell Tumors	TNFRSF14	0.18	0.02	blup	52	0.10	2.4e-04	-1.6	-5.5	3.0e-08	0.73	0.01	0.48	FALSE