[Hub]/) : Traits : Blood Eosinophil Count :

chr6:41,005,502-43,388,216

Best TWAS P=1.13e-11 · Best GWAS P=5.86e-22 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex GUCA1A 0.19 0.17 enet 16 0.19 7.9e-23 -4.4 -6.6 3.4e-11 -0.35 1.00 0.00 TRUE
2 GTEx Artery Aorta GUCA1B 0.16 0.09 lasso 3 0.07 1.5e-04 6.1 -5.9 4.3e-09 -0.61 0.68 0.08 FALSE
3 GTEx Nerve Tibial UBR2 0.14 0.09 lasso 3 0.07 6.9e-06 -5.8 -5.6 2.1e-08 -0.02 0.99 0.00 FALSE
4 GTEx Skin Sun Exposed Lower leg GUCA1B 0.12 0.12 lasso 2 0.09 6.5e-08 5.6 5.5 3.3e-08 0.78 0.98 0.02 FALSE
5 GTEx Testis CCND3 0.25 -0.01 lasso 6 0.00 1.8e-01 -2.9 5.2 1.7e-07 0.03 0.07 0.04 TRUE
6 GTEx Uterus PRPH2 0.37 0.03 enet 7 0.04 4.9e-02 -4.7 6.8 1.1e-11 0.00 0.08 0.06 TRUE
7 NTR Blood MRPS10 0.03 0.02 lasso 9 0.02 1.3e-06 5.8 5.5 3.1e-08 0.74 0.47 0.53 TRUE
8 ROSMAP Brain Pre-frontal Cortex MRPS10 0.30 0.32 lasso 10 0.31 3.2e-41 5.6 5.7 1.5e-08 0.81 1.00 0.00 TRUE
9 ROSMAP Brain Pre-frontal Cortex GUCA1A 0.25 0.18 lasso 3 0.20 2.1e-25 -4.4 -6.3 3.0e-10 -0.34 1.00 0.00 FALSE
10 ROSMAP Brain Pre-frontal Cortex PGC 0.13 0.06 blup 520 0.06 3.2e-08 -1.5 5.2 2.1e-07 0.25 1.00 0.00 TRUE
11 YFS Blood TRERF1 0.06 0.01 bslmm 464 0.03 8.5e-11 -7.2 -6.6 4.1e-11 0.24 0.95 0.03 TRUE
12 The Cancer Genome Atlas Bladder Urothelial Carcinoma GUCA1B 0.18 0.19 lasso 8 0.18 4.3e-15 3.8 -5.4 6.7e-08 -0.60 1.00 0.00 TRUE
13 The Cancer Genome Atlas Esophageal Carcinoma GUCA1B 0.31 0.15 lasso 5 0.18 3.3e-06 6.1 -6.6 3.7e-11 -0.70 0.31 0.34 FALSE
14 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma GUCA1B 0.18 0.12 blup 63 0.15 6.1e-09 5.3 -6.5 1.1e-10 -0.63 0.93 0.07 FALSE
15 The Cancer Genome Atlas Skin Cutaneous Melanoma GUCA1B 0.25 0.25 blup 63 0.27 5.4e-08 2.8 -5.6 2.8e-08 -0.63 0.45 0.51 FALSE