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chr6:87,167,376-88,880,701

Best TWAS P=5.47e-12 · Best GWAS P=8.34e-13 conditioned to 0.00206

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ZNF292	0.04	0.05	lasso	12	0.03	4.1e-05	6.3	-6.3	2.6e-10	0.68	0.51	0.48	FALSE
2	GTEx	Artery Aorta	RP11-393I2.4	0.10	0.03	lasso	5	0.02	2.4e-02	6.0	-6.2	4.3e-10	0.61	0.30	0.46	FALSE
3	GTEx	Artery Coronary	C6orf163	0.27	0.05	lasso	4	0.02	5.9e-02	5.8	5.3	1.1e-07	-0.48	0.11	0.09	FALSE
4	GTEx	Artery Tibial	C6orf163	0.12	0.08	lasso	2	0.07	7.5e-06	5.7	5.6	2.1e-08	-0.54	0.81	0.08	FALSE
5	GTEx	Brain Cortex	SMIM8	0.43	0.24	enet	44	0.34	4.6e-10	4.5	5.3	1.5e-07	-0.57	0.38	0.61	FALSE
6	GTEx	Breast Mammary Tissue	C6orf163	0.13	0.10	lasso	12	0.09	1.5e-05	5.7	5.5	3.3e-08	-0.51	0.91	0.07	FALSE
7	GTEx	Breast Mammary Tissue (Male)	C6orf163	0.09	0.00	enet	4	0.01	2.2e-01	5.8	6.2	6.5e-10	-0.64	0.06	0.31	FALSE
8	GTEx	Cells EBV-transformed lymphocytes	C6orf163	0.18	0.14	lasso	4	0.15	1.5e-05	5.8	5.9	2.8e-09	-0.57	0.46	0.34	FALSE
9	GTEx	Cells Transformed fibroblasts	SMIM8	0.18	0.14	lasso	5	0.12	1.4e-09	5.8	-5.8	5.9e-09	0.57	0.96	0.04	FALSE
10	GTEx	Cells Transformed fibroblasts	C6orf163	0.16	0.14	lasso	3	0.18	2.7e-13	5.8	5.5	3.6e-08	-0.53	0.96	0.04	FALSE
11	GTEx	Lung	RP11-393I2.4	0.09	0.06	lasso	2	0.04	8.4e-04	6.0	-6.0	2.4e-09	0.57	0.72	0.15	FALSE
12	GTEx	Nerve Tibial	ZNF292	0.09	0.07	enet	16	0.10	1.5e-07	-6.5	-6.7	1.5e-11	0.73	0.30	0.70	FALSE
13	GTEx	Nerve Tibial	RP11-393I2.4	0.08	0.09	enet	18	0.09	6.8e-07	5.8	-6.8	1.1e-11	0.73	0.27	0.72	FALSE
14	GTEx	Stomach	C6orf163	0.10	0.06	lasso	1	0.05	2.3e-03	5.8	5.8	6.9e-09	-0.57	0.32	0.12	FALSE
15	METSIM	Adipose	C6orf164	0.05	0.06	lasso	8	0.06	9.3e-10	5.8	6.3	3.7e-10	-0.63	0.95	0.05	FALSE
16	NTR	Blood	C6orf162	0.02	0.02	blup	411	0.02	1.7e-08	-6.5	6.1	1.4e-09	-0.63	0.35	0.65	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	SMIM8	0.21	0.33	enet	34	0.38	3.9e-52	-6.5	5.8	5.7e-09	-0.69	0.28	0.72	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	SLC35A1	0.30	0.48	enet	25	0.50	5.7e-73	-5.9	-6.0	2.5e-09	0.66	0.91	0.09	FALSE
19	The Cancer Genome Atlas	Breast Invasive Carcinoma	C6orf164	0.06	0.05	blup	94	0.06	1.0e-11	-6.4	5.7	1.0e-08	-0.64	0.02	0.98	FALSE
20	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	C6orf164	0.07	0.06	blup	95	0.05	2.0e-03	-6.5	6.7	2.8e-11	-0.73	0.02	0.95	FALSE
21	The Cancer Genome Atlas	Colon Adenocarcinoma	C6orf164	0.05	0.02	enet	8	0.02	1.9e-02	-6.5	6.4	1.2e-10	-0.72	0.02	0.77	FALSE
22	The Cancer Genome Atlas	Esophageal Carcinoma	C6orf164	0.15	0.07	enet	10	0.04	1.7e-02	5.8	5.8	7.4e-09	-0.66	0.02	0.82	FALSE
23	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C6orf164	0.06	0.08	blup	94	0.08	8.3e-09	-6.5	6.4	1.9e-10	-0.71	0.01	0.99	FALSE
24	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SLC35A1	0.02	0.01	blup	72	0.00	8.7e-02	-6.1	5.8	6.9e-09	-0.66	0.01	0.89	FALSE
25	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C6orf164	0.11	0.12	blup	95	0.14	5.0e-15	-6.5	6.1	1.1e-09	-0.65	0.02	0.98	FALSE
26	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C6orf164	0.11	0.14	enet	8	0.12	1.6e-07	-6.5	6.6	5.0e-11	-0.71	0.02	0.98	FALSE
27	The Cancer Genome Atlas	Brain Lower Grade Glioma	C6orf164	0.04	0.02	blup	95	0.04	5.4e-05	5.8	6.6	3.0e-11	-0.69	0.05	0.95	FALSE
28	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZNF292	0.03	0.02	lasso	3	0.02	7.2e-04	4.4	-6.2	7.5e-10	0.66	0.04	0.87	FALSE
29	The Cancer Genome Atlas	Lung Adenocarcinoma	C6orf164	0.09	0.12	blup	95	0.11	4.1e-13	-6.5	6.9	5.5e-12	-0.73	0.02	0.98	TRUE
30	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C6orf164	0.06	0.06	lasso	4	0.07	4.6e-08	-6.5	6.3	3.3e-10	-0.71	0.02	0.98	FALSE
31	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C6orf163	0.06	0.02	blup	66	0.02	1.1e-02	5.8	6.2	5.6e-10	-0.61	0.06	0.68	FALSE
32	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C6orf164	0.12	0.12	blup	95	0.14	7.4e-10	-6.3	6.5	6.0e-11	-0.71	0.02	0.98	FALSE
33	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SLC35A1	0.04	0.03	lasso	5	0.02	1.3e-02	-5.9	5.9	3.0e-09	-0.67	0.03	0.73	FALSE
34	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C6orf164	0.07	0.11	enet	8	0.10	8.4e-05	-6.5	6.5	6.8e-11	-0.74	0.02	0.96	FALSE
35	The Cancer Genome Atlas	Stomach Adenocarcinoma	C6orf164	0.17	0.13	lasso	4	0.10	6.2e-08	-6.5	6.3	3.9e-10	-0.70	0.01	0.99	FALSE
36	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C6orf164	0.12	0.08	enet	9	0.09	5.6e-04	3.1	5.4	7.4e-08	-0.62	0.03	0.91	FALSE
37	The Cancer Genome Atlas	Thyroid Carcinoma	C6orf164	0.18	0.24	lasso	4	0.25	1.4e-24	-6.5	6.6	5.5e-11	-0.72	0.01	0.99	FALSE
38	The Cancer Genome Atlas	Thyroid Carcinoma	SLC35A1	0.08	0.07	enet	17	0.07	5.0e-07	-6.1	-6.2	6.5e-10	0.68	0.01	0.99	FALSE