Best TWAS P=7.23e-55 · Best GWAS P=6.54e-82 conditioned to 4.23e-22
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Liver | MDN1 | 0.30 | 0.28 | lasso | 1 | 0.25 | 9.8e-08 | 5.6 | 5.6 | 2.5e-08 | 0.00 | 0.95 | 0.00 | TRUE |
2 | NTR | Blood | BACH2 | 0.03 | 0.02 | lasso | 3 | 0.02 | 2.1e-06 | -12.6 | 12.5 | 5.3e-36 | -0.57 | 0.36 | 0.63 | TRUE |
3 | YFS | Blood | BACH2 | 0.03 | 0.01 | lasso | 4 | 0.01 | 6.9e-04 | -17.6 | 15.6 | 7.2e-55 | -0.79 | 0.07 | 0.92 | TRUE |