TWAS hub - BACH2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.0309	0.0122	0.00230	0.022	0.009	0.013	0.012	0.017	1.0e-07	0.00053	3.2e-05	6.3e-05	2.1e-06
2	YFS	Blood	0.0251	0.0090	0.00077	0.008	0.008	0.005	0.008	0.008	8.8e-04	0.00091	5.1e-03	1.2e-03	6.9e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Hypothyroidism (self reported)	49.0	112.5	144.0	-12.0	-9.0
Medication: Levothyroxine sodium	47.0	79.6	106.1	-10.3	-7.3
Hypothyroidism/myxoedema (self-reported)	43.9	85.6	114.5	-10.7	-7.5
Asthma (self-reported)	35.5	70.6	74.2	8.2	8.6
Asthma	33.0	65.1	67.2	7.9	8.2
Respiratory disease	32.3	71.9	78.4	8.1	8.9
Blood Eosinophil Count	26.0	200.2	243.4	12.5	15.6
Allergy or Eczema	20.1	52.9	65.1	6.4	8.1
Allergy	19.6	45.0	57.3	-5.7	-7.6
Hayfever, allergic rhinitis or eczema	16.2	35.1	46.7	4.9	6.8
Medication: Ventolin 100micrograms inhaler	14.4	18.5	20.0	4.5	4.1
Medication: Seretide 50 evohaler	12.3	14.2	16.5	3.5	4.1
Hayfever/allergic rhinitis (self-reported)	9.3	12.3	20.3	2.1	4.5
Blood White Count	8.7	64.6	81.6	6.9	9.0
Lung cancer (father)	7.3	8.5	11.5	2.4	3.4
Wheeze or whistling in the chest in last year	6.5	11.5	20.4	1.6	4.5
Crohns Disease (2017)	6.0	13.2	16.1	3.2	4.0
Other serious medical condition/disability diagnosed by doctor	6.0	7.7	12.8	-3.6	-1.6
Irritable Bowel Disease (IBD)	5.5	13.1	20.1	2.5	4.5
Lung FEV1/FVC ratio	5.4	27.4	40.2	-3.8	-6.3
Chest pain or discomfort	5.1	7.4	10.6	2.0	3.3
Crohns Disease (2012)	5.0	8.0	12.7	1.8	3.6
Pain type(s) experienced in last month: Hip pain	5.0	6.3	6.4	-2.5	-2.5
Medication for cholesterol	4.2	6.3	7.9	2.8	2.2
Heel bone mineral density (BMD) T-score, automated (left)	4.1	9.3	14.1	3.8	2.1
Blood Red Count	4.0	38.2	46.1	5.5	6.8
Heart disease (mother)	3.5	4.3	6.4	-2.5	-1.5
Medication: Blood pressure	3.5	6.6	9.2	-3.0	-2.0
Medication: Simvastatin	3.1	4.5	5.0	-2.2	-2.0
Blood clot in the leg (DVT)	3.0	3.9	5.1	-1.7	-2.2
Average weekly beer plus cider intake	3.0	4.3	5.7	2.4	1.7
Ever depressed for a whole week	3.0	3.7	5.0	-2.2	-1.6
Ulcerative Colitis	2.9	4.2	7.9	0.7	2.8
Eye problems/disorders: Diabetes related eye disease	2.9	3.1	3.5	-1.9	-1.7
Diverticular disease/diverticulitis (self-reported)	2.8	3.3	5.5	1.1	2.4
Deep venous thrombosis (DVT) (self-reported)	2.7	3.5	4.5	-1.6	-2.1
Pack years of smoking	2.7	3.9	5.2	-2.3	-1.6
Waist Hip Ratio (WHR)	2.6	11.8	15.5	-3.9	-2.8
Pack years adult smoking proportion	2.6	3.9	4.2	-2.0	-1.9
Number of children fathered	2.6	3.0	3.9	1.4	2.0
Diabetes (father)	2.5	3.1	5.9	-0.6	-2.4
Age when periods started (menarche)	2.5	5.9	6.7	-2.6	-2.2
Average weekly red wine intake	2.5	3.8	4.3	-1.8	-2.1
Supplements: Glucosamine	2.4	3.1	4.0	-2.0	-1.5
Mother’s age at death	2.4	2.9	4.8	-1.1	-2.2
Ulcerative Colitis (UC)	2.3	4.2	7.9	0.7	2.8
Illnesses of mother	2.3	2.8	3.8	1.4	2.0
Birth weight of first child	2.3	4.2	8.4	2.9	0.3
Medication: Bendroflumethiazide	2.3	3.5	7.0	-2.6	-0.3
Bipolar Disorder or Schizophrenia	2.2	5.4	6.0	2.2	2.5
Alzheimer’s Disease (including proxy)	2.2	3.2	5.0	-1.2	-2.2
Osteoarthritis (self-reported)	2.1	2.8	5.3	-2.3	-0.6
Hearing aid user	2.1	2.4	3.4	-1.8	-1.2
Bilateral oophorectomy (both ovaries removed)	2.0	2.3	4.5	-2.1	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	2.0	4.6	7.5	2.7	1.3
Smoking status: Previous	2.0	3.0	3.9	1.5	2.0
Long-standing illness, disability or infirmity	2.0	3.0	4.4	-2.1	-1.3
Financial situation satisfaction	2.0	2.5	2.9	-1.7	-1.4
Cholesterol lowering medication	2.0	2.9	4.1	-1.3	-2.0
Basal cell carcinoma (self-reported)	2.0	2.4	2.8	1.4	1.7
Primary Biliary Cirrhosis	1.9	2.7	3.4	-1.4	-1.8
Rheumatoid Arthritis	1.9	2.6	5.1	-2.3	-0.2
Schizophrenia (2014)	1.9	4.1	5.8	1.6	2.4
Current tobacco smoking	1.9	3.1	3.6	-1.9	-1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.9	2.9	5.8	-2.4	0.3
Mouth/teeth dental problems: Bleeding gums	1.8	2.3	3.4	1.1	1.8
Number of self-reported non-cancer illnesses	1.8	3.2	5.5	-0.9	2.4
Risk taking	1.8	2.6	3.6	1.2	1.9
Medication: Omeprazole (e.g. Zanprol)	1.8	2.2	4.0	0.6	2.0
Supplements: Calcium	1.8	1.9	2.6	1.1	1.6
Mean Putamen Volume	1.7	1.9	2.0	-1.4	-1.4
Heel T-Score	1.7	13.7	18.4	4.3	3.0
Average weekly spirits intake	1.7	2.1	3.6	-0.8	-1.9
Tense / ‘highly strung’	1.7	2.8	5.5	0.2	2.3
Knee pain experienced in last month	1.7	2.6	3.6	-1.3	-1.9
Smoking status: Current	1.7	2.8	2.9	-1.7	-1.6
Bipolar Disorder (2018)	1.6	2.6	2.7	1.6	1.7
Schizophrenia (2018)	1.6	3.3	3.3	1.8	1.8
Father’s age at death	1.6	2.2	3.8	-0.8	-1.9
Happiness	1.6	1.9	3.3	-1.8	-0.7
Family relationship satisfaction	1.6	2.0	2.5	1.2	1.6
Depressed Affect (Nagel 2018)	1.5	3.2	6.0	0.6	2.4
Medication: Allopurinol	1.5	2.0	3.8	0.3	-2.0
Illnesses of siblings: Diabetes	1.5	1.9	3.5	-1.9	-0.5
Pain experienced in last month	1.5	2.5	3.2	1.4	1.8
Alzheimer’s Disease (in mother)	1.4	1.6	2.2	-1.0	-1.5
Serious illness, injury or assault to yourself	1.4	1.7	3.2	-1.8	0.4
Number of incorrect matches in round	1.4	2.3	4.2	0.6	2.1
Number of live births	1.4	1.9	2.1	1.3	1.4
Forced expiratory volume in 1-second (FEV1)	1.4	4.6	8.0	-1.1	-2.8
Exposure to tobacco smoke at home	1.4	1.6	2.7	-0.7	-1.6
Birth weight	1.4	3.1	3.2	-1.8	-1.7
Alcohol intake frequency.	1.4	3.3	4.2	-1.5	-2.1
Illnesses of father: Heart disease	1.4	2.0	3.1	1.8	0.9
Osteoporosis (self-reported)	1.4	1.8	3.0	1.7	0.7
Supplements: Fish oil (including cod liver oil)	1.4	1.8	1.9	-1.3	-1.4
High cholesterol (Self-reported)	1.4	2.5	3.3	-1.8	-1.3
Alcohol drinker status: Never	1.4	1.7	2.1	-1.2	-1.4
Number of operations (self-reported)	1.4	2.1	4.2	-2.0	0.2
Ovarian Cancer	1.3	1.7	2.4	-0.9	-1.6
Ever used hormone-replacement therapy (HRT)	1.3	1.7	3.1	-0.4	1.8
Ever had hysterectomy (womb removed)	1.3	1.5	2.9	-1.7	0.2
Alcohol usually taken with meals	1.3	2.2	3.1	-1.1	-1.8
Reason for reducing amount of alcohol drunk: Health precaution	1.3	1.5	2.8	1.7	0.3
Emphysema/chronic bronchitis	1.3	1.5	1.6	1.2	1.2
Reaction Time	1.2	2.3	4.5	-0.4	-2.1
Lupus	1.2	1.8	2.1	-1.3	-1.4
Blood Platelet Count	1.2	13.8	15.0	3.5	3.9
Pain all over the body in last month	1.2	1.3	2.5	0.1	1.6
Loneliness, isolation	1.2	1.7	3.2	-1.8	-0.4
Myopia	1.2	1.8	2.1	-1.2	-1.5
Schizophrenia vs Biploar Disorder	1.1	1.4	1.5	1.2	1.2
Breast Cancer	1.1	2.7	3.4	-1.9	-1.4
Chronic bronchitis/emphysema (father)	1.1	1.3	2.0	-0.7	1.4
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	3.5	-1.9	-0.2
Medication: Atorvastatin	1.1	1.4	2.8	1.7	0.0
Major Depression (MDD)	1.0	1.2	1.6	-1.3	-0.9
Cardiovascular Disease	1.0	3.2	4.4	-2.1	-1.4
Hair/balding pattern: Pattern 2	1.0	1.2	1.3	-1.1	-1.1
Exposure to tobacco smoke outside home	1.0	1.3	2.3	-1.5	-0.6
Qualifications: nursing, teaching	1.0	1.5	2.9	1.7	0.4
Back pain experienced in last month	1.0	1.4	2.8	-0.1	-1.7
Commuting to job workplace: Cycle	1.0	1.2	1.7	1.3	0.8
Neuroticism (Nagel 2018)	0.9	2.0	2.1	1.4	1.4
Maternal smoking around birth	0.9	1.2	2.5	0.0	1.6
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.3	1.4	-1.1	1.2
Migraine (self-reported)	0.9	1.1	1.9	1.4	0.5
Medication: Omeprazole	0.9	1.1	2.2	0.2	1.5
Pulse rate, automated reading	0.9	2.9	3.9	-2.0	-1.4
Leg pain on walking	0.9	1.1	2.2	-1.5	0.0
Mood swings	0.9	1.7	3.1	0.5	1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	3.1	-0.9	-1.8
Commuting to job workplace: Public transport	0.9	1.1	2.0	-0.4	1.4
Triglycerides	0.8	1.2	1.5	-1.2	-1.0
Past tobacco smoking	0.8	1.5	2.1	-0.9	-1.4
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	1.7	-1.3	0.5
Qualifications: A levels/AS levels or equivalent	0.8	1.8	3.1	1.8	0.6
Depression (self-reported)	0.8	0.9	1.6	-1.3	0.5
Hair/balding pattern: Pattern 4	0.8	2.0	2.8	1.1	1.7
Medication: Paracetamol	0.8	1.4	2.5	-1.6	-0.5
Glaucoma (self-reported)	0.8	1.0	1.6	1.2	-0.6
Health satisfaction	0.8	1.0	2.0	-1.4	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	1.1	-0.9	1.1
Medication: Gliclazide	0.8	0.9	1.3	1.1	0.6
Age started oral contraceptive pill	0.8	1.0	1.9	-1.4	0.3
Heart disease (siblings)	0.8	1.0	1.8	-1.3	0.4
Hand grip strength (left)	0.7	1.9	3.8	0.1	-2.0
Qualifications: CSEs or equivalent	0.7	1.0	1.7	1.3	-0.5
Pulse rate	0.7	1.2	1.3	-1.1	-1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.4	4.5	-0.5	-2.1
Length of working week for main job	0.7	0.8	1.5	1.2	-0.2
Peak expiratory flow (PEF)	0.7	1.7	2.4	1.5	-1.0
Pulse wave reflection index	0.7	0.9	1.1	1.1	0.8
Gout (self-reported)	0.7	1.0	2.0	-0.1	-1.4
Pulse wave peak to peak time	0.7	0.8	1.5	-1.2	-0.3
Supplements: Vitamin C	0.7	0.8	1.4	1.2	-0.4
Number of treatments/medications taken	0.6	1.1	2.0	-1.4	0.5
Diabetes (mother)	0.6	0.7	1.2	0.4	1.1
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	0.7	-0.8	-0.8
Multivitamins +/- minerals	0.6	0.7	1.3	-1.1	-0.5
Medication: Atenolol	0.6	0.7	1.2	0.4	1.1
High blood pressure (mother)	0.6	0.8	1.6	0.2	-1.2
Financial difficulties in last 2 years	0.6	0.7	1.4	-1.2	0.2
Heart attack	0.6	0.7	1.4	-0.4	-1.2
Worrier / anxious feelings	0.6	1.2	1.7	1.3	0.8
Medication: Lansoprazole	0.6	0.7	1.4	-0.0	1.2
Pulse wave Arterial Stiffness index	0.6	0.7	1.3	1.1	0.2
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	1.3	1.1	-0.7
Had major operations	0.6	0.7	1.4	-1.2	-0.1
Eye problems/disorders: Cataract	0.6	0.7	1.4	-1.2	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	1.6	-1.3	0.7
Mineral and other dietary supplements	0.6	0.9	0.9	0.9	1.0
Ever taken oral contraceptive pill	0.6	0.6	0.8	-0.9	-0.7
Heart attack/myocardial infarction (self-reported)	0.6	0.8	1.6	-0.3	-1.2
Alcohol drinker status: Previous	0.6	0.6	0.7	0.8	0.8
Neuroticism (2016)	0.5	0.7	1.4	-1.2	-0.1
Relative age of first facial hair	0.5	1.0	1.0	-1.0	-1.0
Mouth/teeth dental problems	0.5	0.8	1.1	0.7	-1.1
Hip circumference	0.5	2.0	3.5	1.9	0.7
Shortness of breath walking on level ground	0.5	0.6	0.8	-0.9	-0.6
Qualifications: College or University degree	0.5	1.6	2.1	1.1	1.5
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	0.9	0.9	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	1.8	0.3	-1.3
Commuting to job workplace: Walk	0.5	0.5	0.7	-0.8	-0.5
Guilty feelings	0.5	0.7	0.9	-0.7	-1.0
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.2	-1.1	0.2
Eye problems/disorders: Glaucoma	0.5	0.5	0.9	0.4	-1.0
Medication: Lisinopril	0.5	0.6	1.3	-0.2	1.1
Vascular/heart problems diagnosed by doctor	0.5	1.3	2.5	1.6	-0.2
HDL Cholesterol	0.4	0.6	1.0	0.5	1.0
Smoking Status	0.4	0.9	1.8	-1.4	0.1
Neuroticism	0.4	1.0	2.0	-0.1	1.4
Chronotype (morning person)	0.4	1.0	2.0	-0.1	1.4
Hearing difficulty/problems: Yes	0.4	0.7	1.1	-1.1	-0.5
Medication for hormone replacement therapy	0.4	0.4	0.7	0.5	0.8
Taking other prescription medications	0.4	0.5	1.0	-1.0	0.3
High blood pressure	0.4	1.2	2.0	-1.4	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	0.7	0.9	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	0.7	0.4	-0.9
Ever highly irritable/argumentative for 2 days	0.4	0.5	0.8	-0.9	-0.4
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	1.0	0.5	-1.0
Medication: Ibuprofen	0.4	0.5	0.8	0.9	-0.2
Mean time to correctly identify matches	0.4	0.7	1.3	-0.2	-1.2
Commuting to job workplace: Car/motor vehicle	0.4	0.4	0.9	0.1	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	0.6	0.8	-0.5
Average weekly champagne plus white wine intake	0.4	0.6	1.1	1.1	-0.1
Medication: Paracetamol	0.4	0.7	1.4	-1.2	0.1
Fractured/broken bones in last 5 years	0.4	0.6	0.8	0.9	0.5
Worry (Nagel 2018)	0.3	0.5	0.7	0.6	0.9
Alzheimer’s Disease (in father)	0.3	0.3	0.4	-0.5	-0.6
Verbal and Numeric Reasoning (VNR)	0.3	0.7	1.4	1.2	0.0
Fasting Glucose	0.3	0.4	0.6	-0.8	0.4
LDL Cholesterol	0.3	0.4	0.7	-0.4	0.8
Type 2 Diabetes (T2D) (2012)	0.3	0.4	0.5	-0.5	-0.7
Systolic Blood Pressure	0.3	1.6	3.3	-1.8	0.1
Systolic blood pressure, automated reading	0.3	0.7	1.4	0.3	1.2
Vitamin and mineral supplements	0.3	0.4	0.7	0.2	0.9
Severe depression (siblings)	0.3	0.4	0.8	-0.1	0.9
Fed-up feelings	0.3	0.6	1.2	0.0	1.1
Sitting height	0.3	2.0	3.4	1.8	0.7
Waist circumference	0.3	1.0	1.3	-1.1	-0.8
Medication: Ramipril	0.3	0.3	0.5	-0.4	-0.7
Time employed in main current job	0.3	0.3	0.6	0.8	-0.0
Falls in the last year	0.3	0.4	0.7	-0.2	0.8
Prospective memory result	0.3	0.3	0.5	-0.4	0.7
Chronic bronchitis/emphysema (mother)	0.3	0.4	0.7	0.3	0.8
Comparative body size at age 10	0.3	0.7	1.4	0.2	1.2
Number of full brothers	0.3	0.4	0.4	-0.7	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	0.6	-0.8	0.4
Eye problems/disorders: None of the above	0.3	0.4	0.5	0.7	-0.5
Number of full sisters	0.3	0.4	0.5	-0.5	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	0.8	0.2	-0.9
Hypertension (Self-reported)	0.3	0.9	1.6	-1.3	0.5
Ever had bowel cancer screening	0.3	0.4	0.5	-0.7	0.5
Diabetes diagnosed by doctor	0.3	0.5	0.6	-0.6	-0.8
Wears glasses or contact lenses	0.3	0.3	0.7	0.0	0.8
Depression (Nagel 2018)	0.2	0.3	0.5	0.7	-0.0
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.5	1.2	0.2
Type 2 Diabetes (T2D) (2018)	0.2	0.4	0.8	0.2	-0.9
Supplements: Zinc	0.2	0.2	0.4	-0.0	-0.6
Medication: Co-codamol	0.2	0.2	0.4	-0.6	-0.1
Hand grip strength (right)	0.2	0.5	0.7	0.5	-0.8
Townsend deprivation index at recruitment	0.2	0.2	0.4	0.6	0.3
Average weekly fortified wine intake	0.2	0.2	0.4	0.6	-0.1
Nervous feelings	0.2	0.3	0.5	0.7	0.3
Neuroticism score	0.2	0.4	0.7	0.4	0.9
Mouth/teeth dental problems: Dentures	0.2	0.3	0.6	-0.7	-0.2
Impedance of arm (left)	0.2	0.9	1.2	0.8	1.1
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.5	-0.7	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.4	-0.1	-0.6
Comparative height size at age 10	0.2	0.9	1.8	1.3	0.3
Medication: Aspirin	0.2	0.2	0.4	0.6	-0.3
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.3	-0.5	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.4	-0.1	0.7
Breast cancer (self-reported)	0.2	0.2	0.4	0.7	0.1
Miserableness	0.2	0.4	0.7	0.1	0.8
Illnesses of father: High blood pressure	0.2	0.3	0.5	-0.2	0.7
Ever smoked	0.2	0.3	0.5	0.1	0.7
Diastolic blood pressure, automated reading	0.2	0.6	1.0	-1.0	0.3
Unable to work because of sickness or disability	0.2	0.3	0.5	0.7	0.3
Age at First Birth	0.1	0.2	0.4	0.6	0.0
Body Mass Index (BMI) (2010)	0.1	0.2	0.2	-0.4	-0.4
Coronary Artery Disease (CAD)	0.1	0.2	0.3	-0.5	-0.2
HbA1C	0.1	0.1	0.1	0.3	-0.2
Hair Pigment	0.1	1.5	2.9	0.3	1.7
Tanning	0.1	0.8	1.2	-0.6	-1.1
Medication: Metformin	0.1	0.1	0.2	0.3	-0.4
Trunk fat percentage	0.1	0.3	0.4	0.7	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.1	0.3	0.4
Relative age voice broke	0.1	0.1	0.2	0.4	0.1
Leg predicted mass (left)	0.1	0.3	0.6	0.7	-0.2
Trunk fat mass	0.1	0.4	0.7	0.8	0.2
Forced vital capacity (FVC)	0.1	0.5	0.9	-0.1	-1.0
Diabetes (self-reported)	0.1	0.1	0.2	0.2	-0.4
Fluid intelligence score	0.1	0.3	0.4	0.4	-0.6
Impedance of arm (right)	0.1	0.3	0.5	0.7	0.3
Arm fat percentage (right)	0.1	0.4	0.8	0.9	0.0
Trunk fat-free mass	0.1	0.4	0.4	0.5	-0.7
Hair/balding pattern: Pattern 3	0.1	0.1	0.2	0.5	-0.2
Noisy workplace	0.1	0.2	0.3	0.1	-0.6
Medication: Cholesterol lowering	0.1	0.1	0.2	-0.4	-0.3
Arm fat mass (right)	0.1	0.2	0.3	0.5	-0.4
Trunk predicted mass	0.1	0.4	0.5	0.5	-0.7
Breastfed as a baby	0.1	0.1	0.1	-0.3	0.3
Headache pain in last month	0.1	0.2	0.4	-0.6	0.1
Medication: Amlodipine	0.1	0.1	0.2	0.4	-0.2
High blood pressure (siblings)	0.1	0.1	0.2	-0.5	0.1
Forced vital capacity (FVC), Best measure	0.1	0.3	0.3	0.6	0.4
Body fat percentage	0.1	0.3	0.4	0.7	0.3
Worry too long after embarrassment	0.1	0.2	0.3	0.6	-0.4
Age at first live birth	0.1	0.2	0.3	-0.4	-0.5
Medication: Blood pressure	0.1	0.3	0.4	-0.4	0.6
Whole body fat mass	0.1	0.3	0.6	0.8	0.2
Suffer from ‘nerves’	0.1	0.1	0.2	0.5	0.3
Overall health rating	0.1	0.3	0.4	-0.7	0.4
Age at last live birth	0.1	0.1	0.1	-0.2	-0.3
Whole body fat-free mass	0.1	0.3	0.5	0.7	-0.4
Leg fat-free mass (right)	0.1	0.3	0.6	0.8	-0.0
Arm fat percentage (left)	0.1	0.5	0.9	0.9	0.4
Friendships satisfaction	0.1	0.1	0.2	-0.0	0.4
Illnesses of father: None of the above (group 1)	0.1	0.1	0.2	0.4	0.1
Whole body water mass	0.1	0.3	0.4	0.6	-0.5
Leg predicted mass (right)	0.1	0.3	0.6	0.8	-0.2
Arm fat mass (left)	0.1	0.2	0.5	0.7	0.0
Basal metabolic rate	0.1	0.3	0.4	0.6	-0.5
Leg fat percentage (left)	0.1	0.2	0.3	0.5	0.3
Arm fat-free mass (left)	0.1	0.5	1.0	0.1	-1.0
Irritability	0.1	0.1	0.2	-0.5	0.1
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.2	-0.5	0.2
Leg fat mass (left)	0.1	0.3	0.5	0.7	0.0
Arm predicted mass (left)	0.1	0.4	0.6	0.5	-0.8
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.2	0.0
BMI	0.0	0.1	0.2	-0.5	-0.1
Height	0.0	0.1	0.2	0.1	0.4
Lung FVC	0.0	0.1	0.2	0.4	-0.3
Sensitivity / hurt feelings	0.0	0.1	0.2	0.4	-0.1
Frequency of depressed mood in last 2 weeks	0.0	0.0	0.0	-0.0	0.1
Angina	0.0	0.0	0.0	-0.0	-0.1
Impedance of leg (right)	0.0	0.2	0.4	-0.2	-0.6
Leg fat-free mass (left)	0.0	0.2	0.4	0.6	-0.3
Stomach or abdominal pain in last month	0.0	0.0	0.0	-0.0	0.1
Body mass index (BMI)	0.0	0.1	0.1	-0.0	-0.4
Impedance of leg (left)	0.0	0.0	0.0	0.0	-0.2
Hearing difficulty/problems with background noise	0.0	0.0	0.0	0.2	0.1
Had menopause	0.0	0.0	0.0	-0.1	-0.0
Had other major operations	0.0	0.0	0.1	-0.0	0.2
Qualifications: None of the above	0.0	0.0	0.0	-0.1	0.0
Illnesses of siblings	0.0	0.1	0.1	0.2	0.3
Weight	0.0	0.2	0.2	0.5	-0.4
Alcohol intake versus 10 years previously	0.0	0.0	0.1	0.0	0.2
Standing height	0.0	0.3	0.6	0.8	-0.1
Loud music exposure frequency	0.0	0.0	0.0	-0.2	-0.1
Leg fat percentage (right)	0.0	0.0	0.0	0.2	-0.1
Arm fat-free mass (right)	0.0	0.1	0.2	0.4	-0.3
Medication for pain relief, constipation, heartburn	0.0	0.1	0.1	-0.2	0.3
Neck or shoulder pain in last month	0.0	0.0	0.0	-0.1	-0.2
Angina (self-reported)	0.0	0.0	0.0	0.0	-0.1
Leg fat mass (right)	0.0	0.1	0.3	0.5	-0.1
Arm predicted mass (right)	0.0	0.2	0.3	0.5	-0.2
Medication: Aspirin	0.0	0.1	0.1	0.3	-0.2
Impedance of whole body	0.0	0.2	0.2	0.5	0.5

Hub : Genes

BACH2

Models

Trait associations