[Hub]/) : Traits : Blood Eosinophil Count :

chr8:118,508,942-121,136,001

Best TWAS P=9.7e-11 · Best GWAS P=1.67e-10 conditioned to 0.226

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland SAMD12 0.32 0.11 lasso 7 0.16 1.6e-06 6.3 6.4 1.6e-10 0.95 0.01 0.99 FALSE
2 GTEx Brain Cerebellar Hemisphere NOV 0.37 0.10 enet 17 0.20 9.9e-06 5.9 -6.3 3.4e-10 -0.06 0.05 0.94 TRUE
3 GTEx Pancreas SAMD12 0.32 0.13 enet 17 0.15 4.9e-07 5.7 6.5 9.7e-11 0.82 0.03 0.96 TRUE
4 GTEx Skin Not Sun Exposed Suprapubic SAMD12 0.42 0.30 lasso 2 0.29 3.1e-16 6.4 6.4 1.5e-10 1.00 0.01 0.99 FALSE
5 GTEx Skin Sun Exposed Lower leg SAMD12 0.26 0.22 lasso 8 0.21 1.4e-17 6.3 6.5 9.8e-11 0.98 0.01 0.99 FALSE
6 METSIM Adipose SAMD12 0.13 0.11 enet 12 0.11 7.1e-16 6.3 6.3 3.5e-10 0.92 0.01 0.99 FALSE
7 NTR Blood SAMD12 0.19 0.17 lasso 5 0.18 3.7e-55 6.3 6.3 2.3e-10 0.96 0.01 0.99 FALSE
8 ROSMAP Brain Pre-frontal Cortex TNFRSF11B 0.06 0.04 bslmm 499 0.04 2.5e-06 4.9 -5.2 2.2e-07 -0.04 0.83 0.10 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SAMD12 0.07 0.06 enet 6 0.06 4.2e-07 6.4 6.0 2.5e-09 0.91 0.01 0.99 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma SAMD12 0.11 0.04 blup 277 0.05 4.9e-06 5.9 6.0 1.6e-09 0.79 0.01 0.99 FALSE