Best TWAS P=2e-09 · Best GWAS P=9.4e-10 conditioned to 0.107
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | PIGO | 0.10 | 0.07 | enet | 4 | 0.04 | 3.6e-03 | -5.8 | -5.6 | 1.8e-08 | -0.61 | 0.06 | 0.83 | FALSE |
| 2 | GTEx | Artery Tibial | PIGO | 0.05 | 0.00 | lasso | 6 | 0.00 | 8.6e-01 | -5.8 | -5.4 | 5.9e-08 | -0.76 | 0.06 | 0.49 | FALSE |
| 3 | GTEx | Brain Hypothalamus | PIGO | 0.17 | 0.02 | lasso | 3 | -0.01 | 5.4e-01 | 6.0 | -6.0 | 2.0e-09 | -0.91 | 0.03 | 0.58 | TRUE |
| 4 | GTEx | Cells Transformed fibroblasts | PIGO | 0.04 | 0.04 | enet | 12 | 0.03 | 1.5e-03 | -5.6 | -5.4 | 6.4e-08 | -0.61 | 0.09 | 0.66 | FALSE |
| 5 | GTEx | Testis | PIGO | 0.26 | 0.30 | enet | 11 | 0.26 | 6.0e-12 | 4.6 | -5.5 | 4.4e-08 | -0.71 | 0.61 | 0.39 | FALSE |
| 6 | GTEx | Testis | FANCG | 0.23 | 0.12 | enet | 23 | 0.13 | 2.4e-06 | 4.8 | 5.8 | 4.9e-09 | 0.75 | 0.24 | 0.75 | FALSE |
| 7 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | PIGO | 0.05 | 0.03 | lasso | 2 | 0.03 | 6.1e-04 | -5.6 | -5.8 | 8.3e-09 | -0.58 | 0.00 | 0.94 | FALSE |