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chr9:4,093,295-7,345,375

Best TWAS P=2.87e-158 · Best GWAS P=0 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ERMP1	0.15	0.09	bslmm	489	0.11	4.1e-13	1.92	6.8	8.4e-12	0.09	1.00	0.00	TRUE
2	CommonMind	Brain Pre-frontal Cortex	GLDC	0.24	0.10	lasso	6	0.15	8.5e-18	10.74	10.6	3.6e-26	0.13	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	KIAA1432	0.04	0.00	blup	514	0.03	2.7e-04	0.22	8.7	5.1e-18	0.25	0.07	0.04	TRUE
4	GTEx	Breast Mammary Tissue	PDCD1LG2	0.15	0.07	enet	15	0.07	1.3e-04	3.51	6.5	6.9e-11	0.13	0.18	0.11	TRUE
5	GTEx	Breast Mammary Tissue (Male)	PLGRKT	0.11	0.02	enet	28	0.04	3.8e-02	1.12	6.2	5.6e-10	0.02	0.05	0.08	TRUE
6	GTEx	Cells Transformed fibroblasts	ERMP1	0.13	0.09	lasso	5	0.06	3.7e-05	-3.55	-6.0	1.9e-09	-0.14	0.84	0.01	TRUE
7	GTEx	Esophagus Muscularis	IL33	0.17	0.03	enet	29	0.06	1.7e-04	-14.35	17.3	6.1e-67	0.39	0.08	0.33	FALSE
8	GTEx	Nerve Tibial	ERMP1	0.12	0.00	lasso	4	0.01	7.9e-02	-3.55	-5.6	2.0e-08	-0.22	0.20	0.03	FALSE
9	GTEx	Ovary	PLGRKT	0.45	0.11	enet	30	0.30	5.8e-08	5.12	7.3	2.9e-13	0.03	0.18	0.11	TRUE
10	GTEx	Spleen	PDCD1LG2	0.28	0.08	lasso	6	0.19	1.6e-05	3.51	5.3	1.3e-07	0.06	0.08	0.13	TRUE
11	GTEx	Thyroid	ERMP1	0.12	0.03	enet	21	0.09	1.6e-07	10.82	-5.8	6.4e-09	-0.26	0.29	0.12	TRUE
12	NTR	Blood	ERMP1	0.05	0.02	enet	20	0.03	2.1e-11	7.19	-8.3	1.2e-16	-0.30	1.00	0.00	TRUE
13	ROSMAP	Brain Pre-frontal Cortex	RCL1	0.11	0.06	bslmm	641	0.07	9.3e-10	-4.60	-6.4	1.4e-10	-0.08	1.00	0.00	FALSE
14	ROSMAP	Brain Pre-frontal Cortex	GLDC	0.11	0.00	enet	5	0.01	7.4e-03	36.40	26.8	2.9e-158	0.56	0.03	0.62	TRUE
15	ROSMAP	Brain Pre-frontal Cortex	IGHEP2	0.08	0.07	enet	12	0.08	3.7e-10	12.04	-12.0	4.6e-33	0.03	0.26	0.74	TRUE
16	YFS	Blood	ERMP1	0.12	0.05	bslmm	496	0.08	1.1e-24	3.77	-5.8	6.1e-09	-0.19	1.00	0.00	TRUE
17	YFS	Blood	JAK2	0.03	0.03	lasso	4	0.03	1.4e-10	-11.08	12.8	1.8e-37	0.01	0.74	0.26	TRUE
18	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ERMP1	0.14	0.00	enet	15	0.04	2.8e-04	3.99	-5.8	7.2e-09	-0.03	0.04	0.56	TRUE
19	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PDCD1LG2	0.03	0.00	blup	80	0.01	3.9e-02	2.37	7.2	7.1e-13	0.13	0.01	0.29	TRUE
20	The Cancer Genome Atlas	Lung Adenocarcinoma	JAK2	0.07	0.00	blup	83	0.02	2.2e-03	11.92	6.0	2.8e-09	-0.03	0.03	0.18	TRUE
21	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RANBP6	0.24	0.05	blup	38	0.04	6.6e-03	-6.61	-6.9	7.0e-12	-0.16	0.01	0.06	TRUE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	PDCD1LG2	0.13	0.06	lasso	6	0.13	8.2e-14	3.51	5.5	4.8e-08	0.08	1.00	0.00	FALSE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	RLN2	0.05	0.01	enet	9	0.01	1.1e-02	0.86	5.5	4.7e-08	-0.04	0.04	0.07	TRUE
24	The Cancer Genome Atlas	Testicular Germ Cell Tumors	INSL6	0.15	0.06	enet	10	0.06	3.8e-03	11.31	-7.5	9.4e-14	0.03	0.06	0.33	TRUE
25	The Cancer Genome Atlas	Thyroid Carcinoma	GLDC	0.11	0.10	lasso	1	0.09	2.2e-09	-8.27	-8.3	1.4e-16	-0.12	1.00	0.00	FALSE
26	The Cancer Genome Atlas	Thyroid Carcinoma	RCL1	0.06	0.03	blup	130	0.04	1.1e-04	-6.21	-8.0	1.9e-15	-0.08	0.01	0.99	TRUE