TWAS hub - FANCG

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1140	0.0360	1.7e-06	0.061	0.050	0.055	0.062	0.062	5.8e-08	8.4e-07	3.0e-07	4.6e-08	5.1e-08
2	GTEx	Adipose Subcutaneous	0.1710	0.0500	4.9e-05	0.148	NA	0.132	NA	0.141	3.8e-12	NA	6.9e-11	NA	1.4e-11
3	GTEx	Adipose Visceral Omentum	0.1910	0.0680	2.2e-03	0.069	NA	0.048	NA	0.069	1.8e-04	NA	1.7e-03	NA	1.8e-04
4	GTEx	Artery Aorta	0.2180	0.0590	1.3e-06	0.069	NA	0.114	NA	0.105	1.1e-04	NA	7.6e-07	NA	2.0e-06
5	GTEx	Artery Tibial	0.2745	0.0555	6.1e-09	0.170	NA	0.191	NA	0.183	2.8e-13	NA	7.2e-15	NA	2.7e-14
6	GTEx	Brain Cerebellum	0.3030	0.0950	3.0e-05	0.011	NA	0.077	NA	0.051	1.5e-01	NA	2.8e-03	NA	1.3e-02
7	GTEx	Cells EBV-transformed lymphocytes	0.1540	0.0670	4.8e-03	0.014	NA	-0.002	NA	0.002	1.1e-01	NA	3.7e-01	NA	2.6e-01
8	GTEx	Colon Sigmoid	0.2200	0.0710	9.7e-04	0.194	NA	0.198	NA	0.171	2.0e-07	NA	1.5e-07	NA	1.2e-06
9	GTEx	Esophagus Gastroesophageal Junction	0.2730	0.0920	7.8e-04	0.230	NA	0.153	NA	0.193	8.0e-09	NA	3.6e-06	NA	1.5e-07
10	GTEx	Esophagus Mucosa	0.1120	0.0450	3.3e-03	-0.002	NA	0.007	NA	0.011	5.0e-01	NA	1.0e-01	NA	5.7e-02
11	GTEx	Esophagus Muscularis	0.2810	0.0610	2.7e-07	0.218	NA	0.194	NA	0.204	2.2e-13	NA	6.3e-12	NA	1.7e-12
12	GTEx	Heart Left Ventricle	0.4150	0.1249	2.6e-03	-0.002	NA	0.002	NA	-0.005	4.5e-01	NA	2.4e-01	NA	8.8e-01
13	GTEx	Muscle Skeletal	0.0928	0.0451	1.7e-03	0.035	NA	0.020	NA	0.047	2.2e-04	NA	3.8e-03	NA	2.1e-05
14	GTEx	Nerve Tibial	0.1830	0.0553	4.2e-04	0.089	NA	0.066	NA	0.092	7.6e-07	NA	2.1e-05	NA	5.0e-07
15	GTEx	Ovary	0.3040	0.0940	3.1e-03	0.165	NA	0.014	NA	0.117	7.4e-05	NA	1.4e-01	NA	8.3e-04
16	GTEx	Pancreas	0.3940	0.0780	4.8e-10	0.371	NA	0.342	NA	0.364	1.2e-16	NA	3.7e-15	NA	3.1e-16
17	GTEx	Skin Sun Exposed Lower leg	0.0710	0.0280	6.6e-05	0.071	NA	0.057	NA	0.065	1.7e-06	NA	1.7e-05	NA	4.2e-06
18	GTEx	Testis	0.2320	0.0720	1.7e-07	0.124	NA	0.129	NA	0.045	3.8e-06	NA	2.4e-06	NA	4.7e-03
19	GTEx	Thyroid	0.2590	0.0700	2.4e-05	0.124	NA	0.133	NA	0.132	1.1e-09	NA	2.5e-10	NA	2.7e-10
20	YFS	Blood	0.0582	0.0188	4.6e-06	0.032	0.028	0.026	0.032	0.029	1.0e-10	1.6e-09	4.4e-09	1.0e-10	5.9e-10
21	TCGA	Breast Invasive Carcinoma	0.0188	0.0100	3.1e-03	0.003	0.011	0.008	NA	0.006	5.5e-02	1.9e-03	7.0e-03	NA	1.8e-02
22	TCGA	Kidney Renal Clear Cell Carcinoma	0.0551	0.0237	1.0e-05	0.049	0.044	0.053	NA	0.047	3.4e-06	9.0e-06	1.2e-06	NA	4.7e-06
23	TCGA	Brain Lower Grade Glioma	0.0402	0.0215	1.7e-03	0.024	0.015	0.017	NA	0.024	7.9e-04	6.2e-03	4.5e-03	NA	7.8e-04
24	TCGA	Prostate Adenocarcinoma	0.1124	0.0437	1.5e-08	0.086	0.067	0.080	NA	0.081	2.7e-09	1.6e-07	1.1e-08	NA	7.6e-09
25	TCGA	Thyroid Carcinoma	0.1020	0.0380	2.2e-07	0.075	0.074	0.084	NA	0.092	9.4e-08	1.1e-07	1.4e-08	NA	3.2e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	13	14	15	16	17	18	19	20	21	22	23	24	25
Handedness (chirality/laterality): Left-handed	5.8	7.0	12.3	1.9	3.1	3.5	2.7	3.3	1.2	1.5	3.1	3.1	1.2	3.1	-1.0	3.3	3.2	0.2	-0.4	-1.1	3.1	3.0	3.4	3.4	3.1	3.4	3.4
Age at first live birth	5.3	9.4	16.4	-4.0	-3.0	-3.8	-4.0	-3.3	-2.2	-1.9	-3.1	-3.4	-2.5	-3.3	1.1	-3.6	-3.5	-2.3	1.2	1.5	-3.2	-3.3	-3.2	-3.6	-3.6	-3.6	-3.9
Age at last live birth	4.8	7.0	12.5	-3.5	-2.5	-3.2	-3.5	-2.8	-1.8	-1.4	-2.4	-2.7	-2.5	-2.8	1.2	-3.2	-2.9	-2.6	1.0	1.9	-2.6	-2.7	-3.0	-3.3	-2.8	-3.0	-3.2
Diabetes (father)	4.4	5.4	10.9	-3.0	-2.4	-2.5	-2.4	-2.8	0.0	-1.5	-2.0	-2.6	-3.3	-2.5	-0.0	-2.8	-2.5	-2.5	0.7	1.1	-2.6	-3.0	-1.7	-3.1	-1.9	-2.8	-2.8
Average weekly spirits intake	3.1	3.9	9.6	-2.8	-2.2	-2.2	-3.1	-2.3	-0.9	-0.8	-2.3	-2.3	-2.3	-2.5	-0.8	-2.5	-2.5	-1.6	-0.4	0.2	-2.3	-2.2	-0.9	-1.8	-1.4	-2.3	-2.1
Medication: Ibuprofen (e.g. Nurofen)	3.0	3.9	9.2	-1.3	-2.2	-2.5	-3.0	-2.4	-0.7	-1.0	-1.8	-2.4	0.4	-2.4	0.7	-2.4	-2.5	-0.4	0.3	0.8	-2.4	-2.1	-1.8	-2.5	-2.4	-2.4	-2.7
Qualifications: NVQ or HND or HNC or equivalent	2.8	3.3	18.4	-1.3	-0.6	0.0	-0.6	-0.1	-2.8	3.4	-1.5	-0.0	-1.3	-0.4	-3.4	-0.0	-0.2	0.5	-3.8	-4.3	-0.4	-0.0	2.9	1.9	0.2	0.2	0.2
Medication: Ibuprofen	2.7	3.2	8.6	-1.3	-1.9	-2.3	-2.9	-2.1	-0.9	-1.1	-1.8	-2.1	0.1	-2.1	0.8	-2.2	-2.2	-0.3	0.4	0.8	-2.0	-1.7	-1.8	-2.1	-2.4	-2.1	-2.5
Time employed in main current job	2.5	2.9	12.4	1.1	1.4	1.0	1.4	1.0	1.8	-3.1	1.6	0.9	1.4	1.0	3.0	0.9	1.1	-2.1	3.5	3.1	1.2	0.5	-0.7	-0.9	1.5	0.9	1.0
Commuting to job workplace: Walk	2.4	2.6	8.1	2.8	1.4	1.5	1.9	1.6	1.9	0.0	2.8	1.6	1.2	1.8	1.7	1.8	1.6	2.9	0.2	0.6	1.6	1.2	-0.1	1.1	0.9	1.6	1.6
Verbal and Numeric Reasoning (VNR)	2.3	5.5	26.9	1.9	0.5	-0.3	0.5	-0.3	3.0	-4.8	0.9	-0.3	-0.1	0.2	5.2	-0.4	-0.2	-2.1	4.8	5.1	0.1	-0.6	-3.4	-2.6	0.2	-0.7	-0.0
Neuroticism (2016)	2.2	3.2	7.0	2.6	2.1	1.7	2.1	2.1	0.7	-0.1	2.2	2.1	2.3	2.3	1.2	2.2	2.5	1.1	0.8	0.0	2.1	2.1	0.4	2.2	1.4	2.1	1.8
Qualifications: nursing, teaching	2.2	3.4	9.3	-1.3	-1.4	-2.1	-1.4	-1.9	1.2	-1.6	-2.6	-1.9	-3.0	-2.0	0.7	-1.9	-1.9	-2.3	1.7	2.0	-1.7	-1.9	-1.9	-2.2	-1.3	-2.0	-1.9
Basal cell carcinoma (self-reported)	2.2	2.6	4.2	-1.9	-2.0	-1.9	-1.9	-2.0	-1.2	1.4	-1.7	-1.8	-1.4	-1.9	-1.4	-1.8	-1.9	0.4	-1.4	-0.9	-2.0	-2.0	-0.8	-0.8	-1.9	-1.8	-1.9
Alzheimer’s Disease (in mother)	2.1	2.5	6.3	-1.8	-1.7	-1.9	-2.5	-1.8	-1.9	-0.8	-2.0	-1.6	-0.4	-1.7	-0.1	-2.0	-2.1	-0.4	-0.2	0.2	-1.8	-1.6	-1.4	-2.2	-1.3	-1.9	-1.9
Age at First Birth	2.1	3.1	7.4	-1.5	-1.6	-2.1	-1.3	-1.9	-0.5	-1.8	-2.0	-1.9	-0.9	-1.7	1.8	-2.1	-1.8	-1.8	1.4	1.9	-1.8	-1.5	-2.5	-2.7	-1.4	-2.1	-1.7
Chest pain or discomfort	2.1	3.1	6.6	-2.1	-2.0	-1.8	-1.5	-1.6	-1.5	1.9	-1.7	-1.7	-2.5	-1.8	-1.3	-1.8	-1.7	2.6	-2.1	-1.6	-1.8	-1.3	-1.4	-0.4	-2.5	-1.6	-1.7
Alzheimer’s Disease (including proxy)	2.0	3.0	6.8	-1.6	-1.9	-2.1	-2.6	-2.0	-1.1	-1.1	-1.5	-1.9	-0.8	-1.9	0.3	-2.1	-2.2	-0.5	0.1	0.9	-1.9	-1.9	-2.1	-2.6	-1.6	-2.1	-2.2
Mouth/teeth dental problems: Loose teeth	2.0	2.4	10.0	-2.1	-1.6	-2.1	-2.0	-1.7	-3.2	0.1	-1.5	-1.6	-0.6	-1.6	-0.8	-1.8	-1.4	0.2	-0.5	-0.8	-1.6	-1.2	-1.0	-0.8	-2.3	-1.6	-2.1
Neck or shoulder pain in last month	2.0	2.8	7.0	-1.4	-1.6	-1.5	-1.9	-1.3	-1.7	1.8	-1.8	-1.3	-2.6	-1.3	-1.9	-1.5	-1.4	2.5	-2.4	-2.4	-1.5	-0.9	-0.3	0.5	-2.2	-1.2	-1.6
Illness, injury, bereavement, stress in last 2 years	2.0	2.4	7.0	-2.1	-1.6	-1.7	-1.2	-1.8	-0.8	-0.7	-1.1	-1.7	-0.5	-1.6	0.9	-1.8	-1.7	-0.7	0.7	0.9	-1.7	-1.8	-2.1	-2.6	-2.2	-1.9	-1.9
Schizophrenia (2018)	1.9	4.0	18.2	-1.9	-1.4	-1.0	-0.2	-0.8	-1.7	4.0	-1.2	-0.6	-3.2	-0.8	-2.7	-0.6	-0.7	3.2	-4.3	-4.0	-1.1	-0.8	0.8	1.2	-1.8	-0.6	-0.9
Falls in the last year	1.9	2.6	8.6	-2.4	-1.4	-1.2	-1.7	-1.3	-2.6	2.3	-1.5	-1.1	-0.4	-1.2	-2.9	-1.3	-1.3	1.4	-2.3	-2.5	-1.5	-0.9	0.7	-0.4	-1.5	-1.1	-1.3
Illnesses of mother	1.9	2.4	5.4	2.0	1.6	1.7	2.1	1.8	1.4	0.3	2.3	1.7	2.3	1.7	2.0	1.9	1.6	0.7	0.7	0.6	1.8	1.6	0.1	0.6	1.1	1.6	1.6
Ever had stillbirth, spontaneous miscarriage or termination	1.9	2.0	6.0	-0.1	0.9	1.2	0.5	1.3	-1.5	2.4	-0.4	1.3	0.9	0.9	-1.6	1.5	1.2	0.2	-1.7	-2.3	1.1	1.6	2.5	2.2	1.3	1.5	1.6
Illnesses of father: High blood pressure	1.8	2.3	10.0	-1.9	-1.3	-1.4	-1.2	-1.2	-0.2	1.9	-1.7	-1.1	-1.8	-1.1	-3.2	-1.3	-1.1	-0.1	-2.1	-2.0	-1.5	-1.5	1.3	-0.1	-1.3	-1.2	-1.7
HbA1C	1.6	1.7	6.1	1.6	1.6	0.9	0.6	1.1	1.8	-1.9	0.9	1.1	1.1	1.1	1.5	1.3	1.0	-1.5	2.5	2.0	1.4	1.2	-0.5	0.1	1.1	1.2	1.1
Illnesses of father: None of the above (group 1)	1.6	2.0	4.8	1.1	1.6	1.7	1.6	1.6	-0.9	-0.9	1.5	1.3	2.2	1.2	0.8	1.7	1.6	-0.9	1.1	0.6	1.6	1.6	1.2	1.6	1.6	1.6	1.8
Intelligence (Savage-Jansen 2018)	1.5	4.7	26.4	2.0	1.3	0.5	1.2	0.7	3.3	-4.0	1.2	0.7	0.2	1.1	5.1	0.4	0.6	-2.1	4.4	3.9	1.0	0.4	-2.5	-1.9	1.0	0.3	0.8
Medication for hormone replacement therapy	1.5	1.7	4.1	1.2	1.5	1.6	1.9	1.3	0.6	-0.0	1.1	1.3	1.1	1.4	0.6	1.3	1.4	-0.9	1.1	-0.1	1.4	1.7	1.3	0.8	2.0	1.5	2.0
Severe depression (siblings)	1.5	1.7	4.5	-1.4	-1.7	-1.7	-1.2	-1.7	-0.6	0.2	-2.1	-1.7	-0.8	-1.7	-0.5	-1.4	-1.6	-0.6	-0.4	-0.6	-1.7	-1.6	-0.7	-1.0	-1.1	-1.5	-1.5
Average weekly fortified wine intake	1.5	1.8	4.5	1.3	1.5	1.6	1.6	1.2	1.9	-2.1	0.8	1.3	1.1	1.4	1.2	1.3	1.4	-1.6	1.6	0.9	1.3	1.3	0.8	0.3	1.6	1.0	1.4
Chronic bronchitis/emphysema (father)	1.5	1.8	5.5	-0.6	-1.0	-1.3	-0.9	-1.2	0.3	-2.3	-0.8	-1.1	-0.5	-0.9	1.1	-1.4	-1.2	-1.6	1.5	1.9	-1.1	-1.5	-2.0	-2.3	-0.8	-1.5	-1.3
Glaucoma (self-reported)	1.5	1.7	3.4	1.4	1.7	1.6	1.6	1.7	0.9	0.0	1.5	1.6	0.8	1.6	0.3	1.9	1.6	0.8	0.7	-0.1	1.6	1.6	0.9	1.4	1.6	1.7	1.5
Fasting Glucose	1.4	1.7	3.8	1.7	1.4	1.9	1.9	1.5	1.1	0.0	1.4	1.2	-0.4	1.4	-0.3	1.1	1.5	1.1	-0.1	-0.4	1.5	1.3	1.3	1.3	1.8	1.5	1.9
Chronotype (morning person)	1.4	3.1	11.2	-1.0	-2.0	-1.2	-0.8	-1.4	-2.3	1.6	-2.6	-1.6	-1.1	-1.7	-3.0	-1.1	-1.5	2.5	-3.4	-3.1	-1.7	-1.0	0.5	0.4	-1.5	-1.1	-1.0
Ever had hysterectomy (womb removed)	1.4	1.6	5.1	1.5	1.3	1.5	2.2	1.3	1.5	0.2	1.4	1.4	1.4	1.6	-0.2	1.1	1.4	2.3	-0.0	-0.1	1.3	1.5	0.1	0.9	0.5	1.3	1.2
Alcohol intake versus 10 years previously	1.4	2.1	10.6	1.8	0.8	0.8	1.2	0.5	3.2	-2.4	1.4	0.5	0.4	0.7	2.0	0.4	0.6	-1.4	2.4	3.2	0.7	0.2	-1.1	-0.6	1.0	0.3	0.7
Multivitamins +/- minerals	1.3	1.6	10.2	-0.4	-0.3	0.1	-0.4	0.0	-2.3	1.5	-1.3	-0.0	0.5	-0.1	-2.5	0.1	-0.1	1.5	-2.2	-3.2	-0.3	0.7	1.8	1.6	0.0	0.2	0.3
Illnesses of siblings	1.3	1.9	4.0	1.6	1.1	1.3	2.0	1.5	-0.3	1.4	0.9	1.4	1.9	1.3	-0.1	1.7	1.1	1.2	-1.1	-1.7	1.3	1.6	1.4	1.5	1.2	1.6	1.5
Medication: Lansoprazole	1.3	1.5	3.8	1.0	1.1	1.6	1.4	1.2	0.4	1.9	0.8	1.1	1.7	1.1	-0.6	1.1	1.3	0.7	-0.4	-0.8	1.1	1.4	1.6	1.4	1.7	1.3	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	2.1	5.8	1.7	1.0	1.4	1.4	1.5	0.9	2.4	1.3	1.4	0.9	1.3	-0.4	1.5	1.3	1.9	-1.5	-1.3	1.3	1.5	1.3	2.1	1.2	1.6	1.7
Angina (self-reported)	1.3	1.7	3.4	-1.5	-1.7	-1.7	-1.1	-1.5	-1.0	1.2	-1.8	-1.6	-0.9	-1.6	-1.0	-1.5	-1.5	1.0	-1.4	-0.9	-1.6	-1.0	-0.8	-0.3	-1.7	-1.3	-1.3
Blood Eosinophil Count	1.2	8.9	34.2	3.5	2.9	2.2	2.4	2.4	4.1	-4.1	2.7	2.5	2.5	2.4	4.5	2.2	2.3	-3.2	4.9	5.8	2.8	2.2	-1.1	-1.0	2.6	1.9	2.0
Number of incorrect matches in round	1.2	2.0	5.5	-1.0	-1.5	-1.5	-1.4	-1.5	-0.1	1.2	-1.3	-1.4	-1.2	-1.5	-0.1	-1.6	-1.4	2.3	-1.2	-0.8	-1.6	-1.4	-1.6	-1.1	-2.1	-1.6	-1.8
Alcohol usually taken with meals	1.2	1.9	6.9	0.8	1.1	1.2	0.8	1.3	0.6	1.8	-0.2	1.1	-0.5	1.0	-2.5	1.3	1.4	1.3	-1.2	-2.2	1.0	1.4	2.3	2.6	0.8	1.4	1.2
Fluid intelligence score	1.2	2.4	13.1	1.6	0.5	-0.1	0.9	-0.0	2.7	-2.8	0.9	0.0	0.4	0.4	3.6	-0.0	-0.0	-0.4	3.0	3.4	0.2	-0.3	-2.2	-1.6	-0.3	-0.3	-0.1
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	3.9	1.9	1.6	1.5	1.4	1.8	1.1	-1.6	1.8	1.7	0.6	1.6	1.6	2.0	1.5	0.4	0.6	0.5	1.8	1.7	0.2	1.1	1.1	1.7	1.6
High blood pressure (siblings)	1.2	1.7	3.5	-1.7	-1.3	-1.6	-1.4	-1.5	-0.7	-0.1	-1.4	-1.4	-1.9	-1.3	-1.3	-1.9	-1.2	-0.1	-0.4	0.1	-1.5	-1.5	-0.9	-0.9	-1.6	-1.5	-1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	4.2	0.1	1.2	0.9	0.3	1.3	-2.0	1.0	0.1	1.4	0.9	1.3	-1.1	1.1	1.2	1.0	-0.7	-2.1	1.1	1.5	1.6	1.7	0.9	1.2	0.8
Blood Platelet Count	1.1	12.5	60.7	-1.6	-3.0	-1.9	-1.1	-2.0	-3.2	5.6	-1.7	-2.0	-5.7	-1.8	-5.0	-2.2	-1.9	7.8	-6.8	-5.7	-2.6	-2.1	-0.4	1.0	-3.7	-1.7	-2.1
High blood pressure (mother)	1.1	1.6	3.5	-1.7	-1.4	-1.3	-1.2	-1.5	-0.6	-0.4	-1.9	-1.4	-1.7	-1.5	-0.9	-1.6	-1.3	-1.5	-0.3	-0.3	-1.5	-1.6	-0.3	-1.0	-0.8	-1.4	-1.3
Hearing difficulty/problems with background noise	1.1	1.8	3.9	-1.8	-1.3	-1.2	-2.0	-1.3	-1.6	1.6	-1.7	-1.2	-1.1	-1.4	-1.8	-1.5	-1.3	0.5	-1.1	-1.3	-1.4	-1.2	-0.1	-0.6	-1.3	-1.4	-1.5
Medication: Seretide 50 evohaler	1.1	1.2	4.7	-1.1	-1.4	-1.6	-0.7	-1.4	-2.2	-0.1	-1.4	-1.4	-0.1	-1.5	0.5	-1.3	-1.2	-0.4	-0.1	-0.3	-1.3	-0.8	-1.1	-1.0	-0.9	-1.1	-1.1
Knee pain experienced in last month	1.1	1.7	4.4	-0.8	-1.4	-1.5	-1.4	-1.4	0.0	-1.2	-1.3	-1.5	-1.1	-1.5	1.2	-1.5	-1.3	-0.0	0.5	1.6	-1.3	-1.4	-2.1	-1.8	-1.5	-1.4	-1.5
Hearing aid user	1.1	1.3	7.5	0.0	-1.0	-0.7	-0.6	-0.8	-2.0	1.6	-0.9	-0.8	-0.5	-0.9	-1.2	-0.6	-0.8	2.7	-1.6	-1.6	-0.9	-0.7	-0.7	0.2	-1.3	-0.7	-0.8
Myopia	1.1	1.6	3.9	0.6	1.4	1.3	1.5	1.3	1.7	0.5	2.0	1.5	-0.6	1.7	-0.5	1.3	1.6	-0.7	-0.2	-0.2	1.4	1.0	1.6	1.4	1.7	1.3	1.2
Bipolar Disorder or Schizophrenia	1.0	2.4	10.8	-2.0	-1.5	-1.3	-0.6	-1.1	-0.1	2.6	-1.4	-1.0	-3.3	-1.2	-1.4	-0.9	-1.2	1.7	-2.8	-2.4	-1.2	-1.2	-0.1	-0.1	-1.4	-0.9	-1.1
Breast Cancer	1.0	2.3	5.0	-1.8	-1.8	-1.9	-2.2	-1.8	-1.0	0.7	-1.9	-1.9	-0.6	-1.8	-1.8	-1.9	-1.7	-0.7	-0.7	-0.4	-1.9	-1.6	-0.3	-0.7	-1.4	-1.7	-1.9
Schizophrenia (2014)	1.0	2.1	8.3	-1.5	-1.3	-1.2	-0.5	-0.9	-0.3	2.7	-1.3	-0.6	-2.8	-0.8	-1.3	-0.5	-0.8	2.2	-2.9	-2.5	-1.1	-1.0	-0.1	0.4	-1.9	-0.7	-1.0
Angina	1.0	1.3	2.2	-1.3	-1.4	-1.4	-0.8	-1.2	-1.1	1.4	-1.5	-1.3	-0.8	-1.2	-1.1	-1.2	-1.2	1.2	-1.5	-1.1	-1.3	-0.6	-0.4	0.1	-1.5	-0.9	-1.0
Nervous feelings	1.0	1.9	7.7	2.8	1.1	1.7	2.0	1.2	2.4	0.1	1.7	1.4	0.6	1.4	1.1	1.2	1.2	1.4	-0.6	-0.0	1.2	1.0	0.4	0.9	1.6	1.1	1.6
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	4.4	-1.3	-1.1	-1.3	-2.1	-1.2	0.2	-0.4	-0.8	-1.1	-0.3	-1.2	0.7	-1.2	-1.3	-1.7	0.5	0.9	-1.1	-1.1	-0.6	-1.5	-0.4	-1.2	-1.3
Number of children fathered	1.0	1.1	10.3	-1.9	-0.1	-0.6	-1.3	-0.4	-3.2	1.2	-1.5	-0.2	0.2	-0.4	-1.5	-0.5	-0.5	0.4	-0.5	-1.8	-0.5	-0.0	0.4	-0.1	-1.0	-0.4	-0.7
Illnesses of father: Heart disease	1.0	1.3	8.5	1.3	0.9	1.3	0.7	1.1	0.4	1.7	0.9	1.2	0.8	1.2	-0.2	1.0	0.8	2.9	-0.9	-1.1	0.9	1.5	0.2	1.2	0.8	1.1	1.3
Ever used hormone-replacement therapy (HRT)	0.9	1.2	4.6	-0.2	0.7	1.0	0.5	0.8	-0.6	1.6	0.9	0.8	-0.1	0.9	-1.6	0.6	0.7	2.2	-1.1	-2.1	0.6	1.1	1.4	1.2	0.6	1.0	1.2
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	2.4	-0.9	-1.2	-1.2	-1.5	-1.2	-0.3	-0.2	-0.4	-1.2	-0.1	-1.1	-0.2	-1.4	-1.1	0.9	-0.3	0.6	-1.3	-1.2	-1.4	-0.6	-1.6	-1.3	-1.5
Lung cancer (father)	0.9	1.1	2.2	1.2	1.1	1.5	1.2	1.3	-1.0	0.1	1.1	1.2	0.7	1.2	-0.2	0.9	1.3	0.7	-0.2	-0.3	1.2	1.5	0.8	1.1	1.1	1.1	1.4
Headache pain in last month	0.9	1.6	3.6	1.0	0.8	1.2	0.8	1.2	0.3	1.4	1.5	1.3	-1.6	1.4	-1.4	1.0	1.3	1.3	-1.8	-1.6	1.1	0.9	1.6	1.9	0.8	1.1	0.7
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	3.9	0.2	1.3	1.8	0.8	1.6	-0.9	0.7	0.9	1.5	0.7	1.2	-0.7	1.3	1.5	0.6	-0.5	-1.7	1.5	1.8	2.0	1.9	1.6	1.6	1.7
Birth weight	0.9	2.0	8.7	-1.6	-0.9	-1.4	-0.7	-1.2	-0.1	-2.2	-0.0	-1.4	0.2	-1.1	1.4	-1.2	-1.1	-2.9	2.3	2.3	-1.0	-1.3	-1.2	-1.9	-0.6	-1.2	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	5.7	-0.3	0.3	0.3	-0.2	0.4	-0.5	1.7	-0.9	0.3	0.1	0.2	-2.3	0.5	0.4	1.1	-1.4	-2.4	0.2	0.9	1.4	1.7	-0.3	0.6	0.4
Heart disease (mother)	0.9	1.1	2.1	-0.3	-1.3	-1.4	-0.6	-1.3	0.8	-0.4	-1.5	-1.2	-0.9	-1.2	0.2	-1.2	-1.3	0.7	-0.5	0.3	-1.2	-1.3	-1.3	-1.2	-1.2	-1.2	-1.3
Suffer from ‘nerves’	0.9	1.4	6.8	2.6	0.8	1.1	1.6	1.0	2.1	-0.0	1.3	1.1	0.7	1.1	1.4	0.9	1.0	1.9	-0.1	0.8	1.0	0.8	-0.8	0.5	0.7	0.8	1.1
Breast cancer (self-reported)	0.9	1.1	3.3	1.8	0.9	1.1	1.4	1.0	1.6	-0.3	1.3	1.0	0.5	1.0	1.2	0.9	1.1	1.4	0.4	0.8	1.1	1.0	-0.6	0.5	0.9	0.9	1.0
Medication: Gliclazide	0.9	1.0	3.2	0.1	0.9	1.0	0.8	1.1	-1.8	0.5	0.6	1.2	0.3	1.0	-0.5	1.2	1.1	-0.0	-0.8	-1.1	1.1	1.1	1.4	1.6	1.0	1.2	1.1
Type 2 Diabetes (T2D) (2018)	0.8	1.5	4.4	-0.3	-1.3	-1.1	-1.4	-1.5	0.0	-2.1	-1.5	-1.4	-1.2	-1.4	0.3	-1.5	-1.4	-1.2	0.3	1.0	-1.3	-1.5	-1.1	-1.5	-0.6	-1.6	-1.3
Sensitivity / hurt feelings	0.8	1.3	8.6	2.2	0.6	0.9	1.1	1.2	0.9	1.1	0.6	1.0	0.6	0.8	0.5	1.3	1.0	2.9	-1.3	-0.9	1.0	1.1	-0.3	1.1	0.3	1.0	1.0
Frequency of depressed mood in last 2 weeks	0.8	1.1	6.1	0.8	-0.1	0.5	0.4	0.3	-0.6	2.5	-0.7	0.2	0.1	-0.2	-1.0	0.4	0.2	2.3	-2.0	-2.4	0.1	0.4	0.9	1.4	0.4	0.5	0.7
Vitamin and mineral supplements	0.8	1.1	4.0	0.9	1.0	1.0	1.3	1.1	1.6	-0.5	2.0	1.0	-0.7	1.2	1.4	1.0	1.1	-0.0	0.9	1.4	1.2	0.6	-0.4	0.3	0.7	1.0	0.9
Hand grip strength (right)	0.8	2.2	4.7	-2.2	-1.4	-1.8	-2.1	-1.7	-0.6	-0.9	-1.0	-1.7	0.6	-1.7	0.5	-1.5	-1.7	-2.1	0.8	1.1	-1.6	-2.1	-0.7	-1.5	-1.4	-1.7	-1.9
Maternal smoking around birth	0.8	1.2	2.8	-0.4	-1.6	-1.2	-0.7	-1.3	-1.1	0.8	-0.3	-1.2	0.0	-1.1	-1.0	-1.2	-1.0	1.4	-1.7	-0.7	-1.4	-1.6	-0.7	-0.5	-1.1	-1.3	-1.1
Pulse rate	0.8	1.3	3.1	0.5	-1.3	-1.3	-0.1	-1.5	1.2	-0.1	-0.8	-1.3	-0.7	-1.3	0.6	-1.5	-1.2	0.2	-0.0	0.7	-1.4	-1.6	-1.8	-1.6	-1.1	-1.6	-1.4
Medication: Cholesterol lowering	0.8	1.2	3.3	-1.8	-1.2	-1.2	-1.6	-1.3	-1.0	0.8	-1.0	-1.1	-0.8	-1.1	-1.3	-1.4	-1.1	-0.4	-0.5	-0.2	-1.3	-1.2	-0.3	-0.6	-1.0	-1.2	-1.4
Medication: Amlodipine	0.8	1.2	2.8	0.9	1.1	1.2	1.7	1.1	-0.5	1.4	1.3	1.0	-0.0	1.1	-0.2	1.0	1.1	1.3	-0.6	-1.2	1.1	1.3	1.2	1.3	1.0	1.3	1.2
Chronic bronchitis/emphysema (mother)	0.8	1.0	3.0	0.0	1.3	0.8	-0.3	1.4	-1.2	-0.3	0.5	1.2	0.6	1.1	-1.4	1.4	1.2	0.1	0.3	0.0	1.3	1.3	1.0	1.7	0.3	1.4	0.7
Forced vital capacity (FVC), Best measure	0.8	2.9	9.6	-1.9	-1.5	-1.8	-1.8	-1.8	0.9	-1.1	-0.6	-1.9	0.1	-1.8	1.6	-1.7	-1.8	-3.1	1.4	2.0	-1.6	-2.3	-1.5	-2.3	-1.1	-1.9	-2.0
Number of full sisters	0.8	1.0	6.8	0.2	-0.2	-0.0	0.1	0.3	-0.7	2.1	-0.4	0.3	-0.2	0.1	-1.3	0.6	0.2	2.6	-2.2	-1.9	0.2	0.3	0.7	1.3	-0.6	0.5	0.1
Leg pain on walking	0.8	1.0	2.3	-0.9	-1.5	-1.0	-1.3	-1.3	-0.3	0.4	-1.0	-1.3	-0.1	-1.2	-1.2	-1.5	-1.2	0.0	-1.2	-0.5	-1.4	-1.1	0.1	-0.7	-0.6	-1.2	-1.0
Commuting to job workplace: Car/motor vehicle	0.8	0.9	6.4	-1.5	-0.4	-0.9	-1.8	-0.7	-2.5	-0.2	-2.0	-0.5	-0.4	-0.9	-0.8	-0.9	-0.7	-0.9	0.2	-0.4	-0.6	-0.1	0.1	-0.3	-0.6	-0.8	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	4.5	1.0	0.4	0.1	0.7	0.1	2.1	-1.8	0.0	0.0	0.4	0.2	1.5	0.2	0.0	-1.3	1.7	1.9	0.3	0.2	-0.7	-1.0	0.9	0.1	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	7.7	-2.1	-1.2	-1.2	-1.9	-1.2	-1.6	0.1	-1.6	-1.4	-0.8	-1.6	-0.5	-1.3	-1.4	-2.8	0.3	-0.1	-1.2	-1.2	-0.2	-1.0	-0.3	-1.3	-1.2
Friendships satisfaction	0.8	1.0	2.8	-0.5	-1.1	-1.2	-0.6	-1.2	0.2	-0.3	-1.0	-1.0	-1.3	-1.0	-0.1	-1.2	-1.0	-0.3	0.1	0.6	-1.2	-1.7	-1.2	-1.4	-1.2	-1.4	-1.5
Average weekly champagne plus white wine intake	0.8	1.1	6.1	1.4	1.1	1.1	1.0	1.0	-0.8	1.1	0.6	0.9	2.5	0.8	0.0	1.0	1.0	1.1	0.7	-0.4	0.9	1.4	0.7	0.9	0.6	1.0	1.1
High cholesterol (Self-reported)	0.8	1.4	4.5	-0.3	0.7	0.9	0.8	1.0	-0.7	1.0	0.7	1.3	0.1	1.3	-2.1	1.0	1.2	0.6	-2.0	-2.0	0.9	0.9	1.9	1.6	0.9	1.1	0.8
Medication: Bendroflumethiazide	0.8	1.1	2.9	-0.9	-1.0	-1.1	-0.8	-1.1	-0.2	-0.8	-1.6	-1.2	-1.6	-1.1	0.8	-1.4	-1.1	-0.2	0.7	0.5	-1.1	-1.1	-1.7	-1.6	-1.0	-1.2	-1.1
HDL Cholesterol	0.7	1.1	3.6	0.3	0.8	0.6	1.0	0.9	-1.7	1.7	0.1	1.0	0.7	0.9	-0.4	1.1	1.1	0.6	-0.8	-1.8	0.8	1.2	1.5	1.9	0.4	1.1	1.0
Hypothyroidism (self reported)	0.7	1.6	4.1	0.2	1.2	1.5	0.7	1.5	-1.1	0.8	0.6	1.3	0.5	1.1	-0.5	1.4	1.4	0.4	-0.5	-1.8	1.5	1.8	1.9	2.0	1.4	1.7	1.6
Respiratory disease	0.7	1.5	5.3	-1.1	-0.9	-1.0	-2.3	-1.1	-0.2	-1.8	-1.7	-1.2	-0.7	-1.5	-0.3	-1.2	-1.4	-2.1	1.1	1.4	-1.1	-0.9	-0.7	-1.5	-0.5	-1.2	-1.1
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	2.5	-0.6	-1.1	-0.7	-0.5	-1.0	1.2	-0.3	-0.6	-1.1	-1.6	-1.0	-0.1	-1.0	-1.2	0.6	-0.5	0.1	-0.9	-0.9	-0.9	-1.1	-1.0	-0.7	-0.8
Father’s age at death	0.7	0.9	1.8	-0.5	-0.9	-0.8	-1.1	-1.1	0.9	-1.3	-0.2	-1.1	-0.8	-0.8	0.5	-1.2	-0.9	-1.2	0.7	1.2	-1.0	-1.3	-0.7	-1.2	-0.5	-1.1	-1.1
Number of live births	0.7	0.9	9.2	-0.5	-0.4	-0.3	-0.9	-0.1	-1.0	1.6	-0.4	-0.1	-0.3	-0.2	-1.1	-0.1	-0.3	3.0	-1.6	-1.6	-0.3	0.2	-0.3	0.2	-1.5	-0.1	-0.5
Worry too long after embarrassment	0.7	1.2	6.4	1.3	-0.3	-0.5	-0.3	-0.3	1.3	-2.3	-1.1	-0.6	0.9	-0.6	2.5	-0.3	-0.5	-0.6	1.4	1.7	-0.2	0.0	-1.9	-1.0	-0.3	-0.5	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	4.5	1.5	0.2	0.6	0.6	0.7	1.8	1.3	0.8	0.7	-0.2	0.5	0.2	0.9	0.6	2.1	-1.6	-0.5	0.6	0.5	-0.0	1.4	0.4	0.7	0.8
Eye problems/disorders: None of the above	0.7	0.8	3.0	0.0	0.7	1.0	0.4	0.9	-0.1	-0.2	0.7	1.0	1.0	1.0	-1.4	0.9	0.9	-1.0	-1.0	-0.8	0.8	0.8	1.7	0.6	1.2	0.8	0.9
Supplements: Vitamin C	0.7	0.8	2.3	-1.5	-0.7	-1.0	-0.9	-0.9	-1.4	-0.5	-1.2	-0.9	1.1	-1.0	-0.3	-1.0	-0.9	-1.1	0.3	0.2	-0.8	-0.7	-0.6	-1.1	-0.7	-0.8	-0.9
Illnesses of siblings: Diabetes	0.7	0.8	5.0	-1.1	0.1	-0.4	-1.2	-0.3	-0.3	-1.7	-0.9	-0.3	-0.4	-0.6	0.6	-0.2	-0.4	-2.2	1.9	1.6	-0.1	-0.2	-0.7	-0.7	0.0	-0.3	-0.4
Medication: Atorvastatin	0.7	0.9	5.2	-0.1	-0.2	0.1	0.2	0.2	-0.1	1.7	0.4	0.3	-1.6	0.3	-2.0	0.1	0.2	1.7	-2.3	-1.4	0.0	0.2	0.8	1.1	0.1	0.3	0.1
Fractured/broken bones in last 5 years	0.7	0.9	2.4	0.1	0.8	0.6	0.1	0.9	-1.3	0.6	-0.7	0.9	0.9	0.5	-0.5	1.1	0.8	-0.8	-0.2	-1.5	0.9	1.4	1.5	1.4	1.5	1.0	1.0
Pain experienced in last month	0.7	1.1	7.7	-0.3	-0.0	-0.2	0.3	-0.6	0.3	-1.2	-0.5	-0.4	1.3	-0.6	1.7	-0.4	-0.5	-2.8	2.2	1.6	-0.4	-0.7	-0.5	-1.5	0.7	-0.6	-0.0
Heart attack/myocardial infarction (self-reported)	0.7	0.9	3.8	1.1	1.0	1.0	1.0	1.0	0.7	1.3	1.4	0.9	1.9	1.0	-0.4	0.9	0.9	0.8	-0.2	-0.3	0.9	0.9	0.7	0.9	0.9	1.0	0.9
Bipolar Disorder (2018)	0.6	0.9	3.6	-0.8	-0.6	-0.8	-0.7	-0.8	1.9	-0.9	-0.7	-0.9	-1.3	-1.0	1.0	-0.7	-1.0	-1.3	0.9	1.3	-0.6	-0.9	-1.1	-1.6	-0.1	-0.8	-0.6
Schizophrenia vs Biploar Disorder	0.6	0.8	5.6	-0.1	-0.5	-0.1	-0.2	0.1	-0.9	1.3	0.4	0.2	-1.1	0.2	-1.2	0.0	-0.1	1.8	-2.4	-1.7	-0.2	-0.1	0.6	0.9	-0.7	0.0	-0.3
Bipolar Disorder (2011)	0.6	0.6	5.4	-1.2	-0.6	-0.7	-0.7	-0.5	1.1	0.6	-0.4	-0.7	-2.3	-0.7	-0.3	-0.4	-0.8	-0.5	-0.4	-0.5	-0.5	-0.7	0.2	-0.2	-0.5	-0.4	-0.5
Lupus	0.6	0.9	5.7	-0.4	0.4	0.8	0.8	0.5	-1.0	2.4	1.3	0.5	0.4	0.6	-1.3	0.4	0.5	1.3	-1.4	-1.4	0.4	0.6	1.1	1.2	0.4	0.7	0.8
Blood White Count	0.6	4.3	20.0	-0.8	-1.9	-1.4	-0.1	-1.3	-2.2	3.9	-1.0	-1.1	-2.3	-1.0	-2.8	-1.3	-1.0	4.0	-4.5	-3.2	-1.6	-1.1	0.4	1.0	-2.4	-1.1	-1.4
Relative age of first facial hair	0.6	1.2	8.8	1.3	0.6	0.6	0.9	0.1	3.0	-1.2	1.0	0.2	1.2	0.4	1.6	0.2	0.2	-1.4	1.9	1.9	0.2	0.0	-0.2	-1.0	1.2	0.0	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	3.1	-0.8	-1.0	-0.8	-0.9	-0.9	-1.8	0.9	-1.7	-1.0	-1.1	-1.3	-0.5	-0.9	-0.9	0.1	-0.7	-1.2	-0.9	-0.8	-0.2	-0.1	-0.4	-0.7	-0.6
Financial difficulties in last 2 years	0.6	0.8	3.6	-0.2	0.3	0.3	0.3	0.7	-0.1	1.0	0.8	0.6	-1.0	0.6	-1.4	0.7	0.7	-0.4	-1.4	-1.2	0.5	0.5	1.9	1.9	0.7	0.7	0.4
Heart attack	0.6	0.8	4.0	1.0	0.8	0.9	0.9	0.9	0.7	1.1	1.3	0.8	2.0	0.9	-0.3	0.8	0.8	0.9	-0.1	-0.1	0.8	0.8	0.5	0.8	0.8	0.9	0.8
Neuroticism score	0.6	1.3	7.8	2.8	0.7	1.1	1.3	1.0	1.3	-0.3	0.5	0.9	1.7	0.8	1.6	1.1	0.9	1.7	-0.3	0.2	1.0	0.9	-0.7	0.8	0.8	0.9	1.2
Qualifications: A levels/AS levels or equivalent	0.6	1.3	4.2	-0.9	-0.6	-1.6	-1.2	-0.8	1.1	-1.8	-1.1	-0.9	-2.1	-0.8	0.7	-0.9	-1.0	-1.4	1.3	1.3	-0.7	-0.7	-1.3	-1.2	-0.9	-0.8	-1.5
Prospective memory result	0.6	0.7	5.4	-0.0	-0.2	-0.0	-0.9	0.1	-2.3	0.9	-0.4	0.0	1.2	-0.3	-1.4	0.3	-0.2	1.2	-1.2	-1.6	-0.0	0.4	0.6	0.9	-0.1	0.3	0.1
Pulse wave reflection index	0.6	0.8	1.6	-0.1	1.2	0.9	0.4	1.1	0.9	-0.1	0.7	1.2	0.1	1.2	-0.2	1.2	1.1	-0.9	0.5	0.0	1.1	1.1	1.3	0.7	1.0	1.0	0.8
Alcohol intake frequency.	0.6	1.3	5.0	1.3	1.4	1.4	1.1	1.2	2.2	-0.7	1.2	1.5	0.3	1.5	0.4	1.3	1.6	-0.7	0.7	0.9	1.3	1.0	0.8	0.8	1.3	1.0	1.1
Back pain experienced in last month	0.6	0.9	3.3	1.2	0.9	1.1	0.4	1.1	0.6	0.7	0.8	1.0	-0.3	1.0	-0.7	1.0	0.9	1.8	-0.9	-0.8	0.9	1.2	0.8	1.3	1.0	1.1	1.1
Miserableness	0.6	1.0	2.7	0.8	0.9	1.2	0.6	1.1	-0.2	0.8	1.7	1.1	0.9	1.1	0.5	1.1	1.0	1.4	-0.8	-1.1	1.2	1.0	0.8	1.3	0.5	1.3	1.0
Ever taken oral contraceptive pill	0.6	0.6	4.0	-0.2	-0.6	-0.9	-0.4	-0.9	-2.0	0.6	-0.6	-0.6	1.5	-0.6	0.1	-0.8	-0.6	-0.1	0.3	-0.4	-0.8	-0.7	-0.4	-1.0	-0.8	-0.8	-0.9
Risk taking	0.6	0.9	3.8	-0.5	-0.4	-0.4	-0.7	-0.0	-1.9	1.9	-0.6	-0.1	-0.5	-0.3	-1.2	0.0	-0.1	1.7	-1.8	-1.8	-0.2	0.1	0.4	1.0	-0.5	0.0	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	2.0	1.1	0.9	1.3	0.4	0.9	0.7	0.3	0.9	1.1	0.7	0.9	-0.2	0.8	1.0	-0.2	0.2	0.3	1.0	1.1	0.8	0.7	1.4	1.0	1.3
Worry (Nagel 2018)	0.5	1.1	6.9	2.6	0.3	0.8	1.5	0.6	1.7	0.6	0.8	0.6	0.7	0.6	0.9	0.7	0.6	2.4	-0.9	0.0	0.6	0.6	-1.1	0.7	0.4	0.6	0.9
Alzheimer’s Disease (in father)	0.5	0.6	2.4	0.2	-0.2	-0.4	-0.5	-0.2	1.1	-1.5	-0.1	-0.4	-1.1	-0.4	1.2	-0.3	-0.4	-0.6	1.2	1.5	-0.1	-0.1	-1.3	-1.1	-0.1	-0.2	-0.3
Crohns Disease (2017)	0.5	1.1	7.6	-0.2	-1.0	-0.7	-1.2	-0.8	-0.2	0.3	-1.0	-1.0	-2.8	-1.0	-2.5	-0.7	-1.0	0.4	-1.4	-0.9	-0.9	-0.9	0.1	0.5	-0.3	-0.6	-0.6
Irritable Bowel Disease (IBD)	0.5	1.1	10.4	-0.3	-1.0	-0.7	-0.9	-0.9	0.0	0.4	-1.2	-1.0	-3.2	-0.9	-2.1	-0.9	-0.9	-0.2	-1.2	-0.7	-1.0	-1.1	0.0	0.1	-0.1	-0.8	-0.5
Coronary Artery Disease (CAD)	0.5	0.5	2.0	0.2	0.4	0.3	-0.2	0.7	-0.1	0.4	0.1	0.9	-1.0	0.7	-0.9	0.9	0.7	1.4	-1.2	-1.1	0.6	0.6	0.4	1.4	-0.6	0.7	0.1
Ulcerative Colitis	0.5	0.8	5.9	1.6	0.6	0.8	1.5	0.6	2.4	-0.3	0.3	0.7	-1.1	0.7	0.8	0.7	0.8	-0.1	0.1	0.3	0.7	0.5	-0.0	0.3	1.0	0.6	1.0
Supplements: Zinc	0.5	0.6	2.2	0.4	0.8	0.6	0.5	0.9	-1.1	-0.1	0.3	0.8	0.4	0.8	-0.7	0.9	0.8	0.4	0.0	-0.7	0.8	1.3	0.8	1.5	0.5	1.0	0.7
Diabetes (mother)	0.5	0.6	2.9	-0.6	-0.1	0.4	-0.2	-0.0	-1.3	1.2	0.0	0.0	-1.6	-0.0	-1.7	-0.3	0.2	0.1	-1.3	-1.3	-0.0	-0.0	1.4	0.9	0.3	0.1	0.2
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.2	0.4	0.8	0.8	1.1	0.9	0.8	-0.5	0.5	0.9	0.5	0.8	-0.4	1.0	0.9	-0.1	-0.2	-0.3	0.9	1.1	0.9	1.1	0.5	0.9	0.7
Serious illness, injury or assault to yourself	0.5	0.6	2.2	0.4	0.4	0.5	0.6	0.6	-0.2	1.1	0.3	0.5	-0.3	0.5	-1.5	0.6	0.4	1.3	-0.8	-1.2	0.6	0.7	0.7	1.1	0.8	0.9	0.7
Supplements: Glucosamine	0.5	0.7	1.8	0.2	-0.4	-1.1	-1.2	-0.7	-0.6	-1.3	-1.2	-0.8	0.4	-0.8	0.5	-0.6	-0.9	0.7	1.3	0.6	-0.7	-0.2	-1.3	-0.9	-1.1	-0.6	-0.7
Forced vital capacity (FVC)	0.5	2.0	10.9	-2.0	-1.2	-1.5	-1.5	-1.4	0.9	-1.1	-0.6	-1.5	0.3	-1.4	1.1	-1.1	-1.5	-3.3	1.0	1.4	-1.2	-1.7	-0.7	-1.7	-0.7	-1.4	-1.5
Mouth/teeth dental problems	0.5	0.8	5.2	1.6	0.3	0.9	1.1	0.3	2.3	-1.2	0.6	0.2	0.1	0.2	1.6	0.5	0.3	-0.4	0.9	1.2	0.4	0.1	-0.2	0.1	1.1	0.4	0.9
Medication: Ramipril	0.5	0.7	2.2	0.5	0.9	1.1	0.8	0.9	-0.1	0.8	0.5	0.9	1.5	0.9	-0.6	0.7	0.9	0.1	-0.1	-0.7	0.8	0.8	1.1	1.1	1.1	0.8	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	4.4	-0.3	-0.8	-0.6	-0.7	-0.6	-1.3	1.5	-0.9	-0.5	-1.1	-0.9	-0.7	-0.6	-0.6	2.1	-1.4	-1.0	-0.6	-0.5	-0.7	0.1	-0.8	-0.5	-0.6
Happiness	0.5	0.6	2.4	-0.2	-1.0	-0.6	0.0	-0.9	0.8	1.0	-0.7	-0.8	-1.6	-0.9	-0.7	-0.7	-0.9	0.1	-1.3	-0.7	-0.9	-1.2	0.2	-0.4	-0.6	-0.8	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	9.0	-1.7	-1.0	-1.2	-1.3	-1.2	1.6	-0.7	-0.3	-1.3	-0.3	-1.3	0.9	-1.1	-1.3	-3.0	0.9	1.6	-1.1	-1.7	-0.5	-1.5	-0.3	-1.3	-1.3
Breastfed as a baby	0.5	0.7	3.3	1.4	0.9	0.6	0.7	0.6	0.7	-0.8	0.5	0.6	0.3	0.6	1.4	0.6	0.7	0.4	1.8	1.1	0.7	0.7	-0.7	-0.1	0.7	0.5	0.7
Tense / ‘highly strung’	0.5	0.8	6.3	0.7	0.2	0.6	0.5	0.6	-0.5	1.5	0.6	0.5	1.2	0.3	-0.1	0.7	0.4	2.5	-1.5	-1.1	0.5	0.5	-0.3	0.9	0.1	0.7	0.7
Exposure to tobacco smoke outside home	0.5	0.6	1.5	-0.3	-0.8	-0.9	-1.2	-0.9	0.5	-0.9	-1.2	-0.9	-0.1	-0.9	0.1	-0.7	-0.8	-0.3	0.2	0.7	-0.9	-1.0	-0.5	-0.6	-1.0	-1.0	-1.0
Comparative body size at age 10	0.5	1.4	5.9	-1.9	-1.1	-1.3	-1.7	-1.1	-2.4	0.6	-1.4	-1.1	-0.8	-1.3	-0.8	-1.1	-1.3	-1.1	-0.6	-0.8	-1.2	-1.0	0.3	-0.5	-1.0	-1.1	-1.3
Hypertension (Self-reported)	0.5	1.4	6.2	-1.3	-0.8	-0.5	-0.1	-0.7	-2.0	2.5	-1.1	-0.6	-1.4	-0.8	-2.4	-1.1	-0.5	0.7	-1.9	-2.0	-0.8	-0.4	0.9	0.4	-0.3	-0.4	-0.4
Ever had bowel cancer screening	0.5	0.6	1.6	-1.2	-0.6	-0.7	-1.2	-0.8	-0.6	0.1	-1.2	-0.7	-1.0	-0.9	-1.2	-0.8	-1.0	-0.3	0.1	0.3	-0.9	-0.7	-0.2	-0.6	-0.7	-0.9	-0.7
Wears glasses or contact lenses	0.5	0.6	4.9	1.4	0.5	0.5	1.3	0.4	0.6	0.3	1.0	0.6	-1.4	0.8	-0.2	0.3	0.6	2.2	-0.2	-0.3	0.5	0.4	-0.5	0.2	0.1	0.6	0.4
Tinnitus: Yes, now most or all of the time	0.5	0.6	4.1	-0.6	-0.5	-0.7	-0.8	-0.6	-2.0	-0.5	-0.9	-0.5	-0.2	-0.6	0.8	-0.7	-0.8	-0.8	0.4	0.2	-0.6	-0.6	-0.8	-1.2	-0.1	-0.7	-0.6
Supplements: Fish oil (including cod liver oil)	0.5	0.6	3.4	1.5	0.8	0.6	1.1	0.5	0.2	0.3	-0.4	0.6	0.8	0.6	-0.3	0.6	0.7	1.9	-0.0	-1.0	0.5	1.1	0.1	0.9	0.9	0.7	0.9
Medication: Lisinopril	0.5	0.6	5.7	-0.6	-0.5	-0.4	0.0	-0.4	-2.4	1.2	-0.7	-0.4	-0.4	-0.4	-1.4	-0.6	-0.2	0.9	-0.9	-1.1	-0.5	-0.1	0.4	0.2	-0.8	-0.3	-0.4
Alcohol drinker status: Never	0.5	0.6	3.3	0.2	-0.8	-0.3	-0.0	-0.7	0.1	1.2	-1.1	-0.6	-0.0	-0.5	-1.8	-0.8	-0.4	1.1	-1.6	-1.1	-0.8	-0.3	0.4	0.6	-0.8	-0.6	-0.5
Age started oral contraceptive pill	0.5	0.7	3.3	0.9	0.2	0.1	0.5	-0.2	1.1	-1.5	-0.0	-0.0	0.9	0.0	1.8	-0.1	0.1	-0.2	1.5	1.6	-0.1	-0.3	-1.1	-1.1	-0.2	-0.3	-0.1
Diastolic blood pressure, automated reading	0.5	1.6	3.8	-1.6	-1.2	-1.2	-1.8	-1.0	-1.4	1.5	-1.9	-0.9	-1.8	-1.3	-1.5	-1.2	-1.0	0.2	-1.5	-1.3	-1.1	-1.1	-0.2	-0.6	-1.1	-1.1	-1.4
Supplements: Calcium	0.5	0.5	1.7	-1.2	-0.7	-0.9	-0.4	-0.9	-1.3	0.2	-0.9	-0.8	-0.5	-0.7	-0.3	-1.0	-0.8	0.4	-0.0	-0.4	-0.9	-0.3	-0.7	-0.7	-0.9	-0.9	-0.8
Major Depression (MDD)	0.4	0.5	1.5	-1.2	-0.8	-1.0	-0.1	-0.7	-0.9	1.0	-0.8	-0.6	-0.5	-0.6	-1.0	-0.5	-0.6	0.3	-1.0	-0.8	-0.7	-0.5	-0.2	-0.3	-1.0	-0.5	-0.8
Crohns Disease (2012)	0.4	0.7	4.6	0.8	-0.8	-0.6	-0.3	-0.7	1.8	-0.4	-1.2	-1.0	-2.1	-1.0	-0.1	-0.4	-1.0	-0.7	0.2	0.9	-0.7	-0.7	-0.8	-0.1	0.2	-0.4	-0.1
Blood Red Count	0.4	4.1	19.3	-1.0	-1.4	-0.6	-0.1	-0.6	-2.6	3.9	-1.8	-0.6	-1.1	-0.9	-3.1	-0.5	-0.5	3.9	-4.4	-4.3	-1.0	-0.4	1.2	1.9	-1.7	-0.3	-0.6
Neuroticism	0.4	1.1	7.5	2.1	0.3	0.8	0.9	0.8	0.2	0.9	0.1	0.8	1.3	0.7	0.1	0.9	0.7	2.7	-1.6	-1.2	0.7	0.9	-0.3	0.9	0.4	0.7	0.9
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	2.3	1.1	0.4	0.5	0.5	0.3	1.5	0.2	0.7	0.2	0.6	0.2	1.4	0.4	0.3	-0.5	1.1	1.0	0.4	0.1	0.0	-0.2	0.5	0.3	0.3
Medication: Metformin	0.4	0.6	1.5	-0.6	-0.8	-0.6	-0.7	-0.9	-0.9	-0.4	-1.1	-0.9	-0.0	-1.0	0.2	-0.9	-0.8	-1.2	0.4	0.4	-0.8	-0.7	-0.3	-1.0	-0.1	-0.9	-0.6
Impedance of leg (right)	0.4	1.9	9.8	0.3	0.8	0.2	-0.7	0.4	2.4	-3.1	1.0	0.4	0.6	0.6	2.3	0.4	0.1	-2.0	2.5	2.6	0.7	0.3	-1.3	-1.5	0.5	0.2	-0.1
Relative age voice broke	0.4	0.7	4.0	1.6	0.6	0.4	0.2	0.2	1.0	-1.0	1.0	0.1	0.8	0.2	1.2	0.1	0.1	-0.5	2.0	1.9	0.3	0.3	-0.6	-0.4	0.6	0.1	0.3
Age when periods started (menarche)	0.4	1.0	3.6	1.9	0.8	1.1	1.1	0.9	0.8	-0.9	0.7	0.9	1.6	0.6	1.5	0.9	0.9	1.3	0.7	0.6	1.0	1.2	-0.9	0.4	0.9	0.9	1.0
High blood pressure	0.4	1.0	5.9	-1.0	-0.5	-0.2	0.1	-0.4	-1.8	2.4	-0.6	-0.4	-1.3	-0.4	-2.1	-0.8	-0.3	0.9	-1.7	-1.7	-0.5	-0.2	0.8	0.5	-0.1	-0.2	-0.1
Impedance of leg (left)	0.4	2.0	10.9	0.2	0.6	0.2	-0.8	0.2	2.8	-3.3	1.0	0.2	0.7	0.5	2.3	0.3	-0.1	-2.3	2.3	2.6	0.5	-0.1	-1.2	-1.7	0.5	-0.0	-0.2
Hair/balding pattern: Pattern 2	0.4	0.5	2.5	0.9	0.9	1.1	0.7	0.7	1.6	-0.3	0.7	0.7	-0.3	0.5	0.4	0.4	0.7	0.3	0.9	0.7	0.7	0.8	-0.1	0.2	0.5	0.6	0.9
Pain all over the body in last month	0.4	0.4	1.4	-0.6	-0.1	-0.3	-1.1	-0.3	0.2	-1.0	-0.2	-0.4	0.7	-0.4	1.0	-0.4	-0.5	-0.4	1.2	0.9	-0.2	-0.3	-1.1	-1.1	-0.5	-0.5	-0.5
Hair/balding pattern: Pattern 3	0.4	0.6	2.1	-1.5	-0.6	-0.7	-0.6	-0.7	-0.2	0.9	-0.5	-0.6	-0.4	-0.5	-1.2	-0.6	-0.5	-1.3	-0.9	-0.9	-0.7	-0.8	1.0	0.2	0.2	-0.5	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	3.1	0.6	0.6	0.1	-0.5	0.1	0.7	-1.8	-0.1	0.3	-0.4	0.3	1.0	0.2	0.1	-0.6	1.6	1.1	0.2	0.1	-0.4	-0.3	0.3	-0.1	-0.0
Asthma	0.4	0.7	2.9	0.0	-0.3	-0.6	-1.3	-0.6	-0.2	-1.4	-0.7	-0.6	0.1	-0.8	0.7	-0.8	-0.7	-1.0	1.5	1.7	-0.5	-0.2	-1.2	-1.1	-0.3	-0.7	-0.6
Depression (self-reported)	0.4	0.5	4.9	1.2	-0.2	0.2	-0.1	0.2	-0.4	1.0	0.4	0.1	-0.1	0.1	-0.2	0.2	0.0	2.2	-1.5	-0.8	0.0	0.4	0.1	0.9	0.1	0.3	0.4
Pulse wave Arterial Stiffness index	0.4	0.4	2.0	-1.4	-0.6	-0.8	-0.7	-0.7	0.2	0.7	-0.4	-0.5	-0.6	-0.4	-0.8	-0.7	-0.4	-0.6	-0.6	-0.8	-0.7	-0.7	0.3	-0.4	-0.6	-0.7	-0.8
Impedance of arm (left)	0.4	1.7	8.1	1.3	1.0	1.0	0.2	0.9	2.9	-2.3	1.4	0.8	0.3	1.0	2.4	0.9	0.6	-1.0	1.8	2.0	1.1	0.9	-0.6	-0.6	1.3	0.8	0.9
Exposure to tobacco smoke at home	0.4	0.4	2.3	0.6	0.5	0.3	0.2	0.5	0.7	-0.8	0.6	0.5	0.3	0.3	1.5	0.5	0.4	-0.5	1.0	1.1	0.6	0.4	-0.8	-0.6	0.7	0.3	0.4
Ever highly irritable/argumentative for 2 days	0.4	0.5	2.7	1.1	0.5	0.6	0.4	0.5	0.6	-1.1	0.7	0.5	0.9	0.5	1.7	0.4	0.4	0.2	0.7	1.0	0.6	0.5	-0.3	-0.1	0.6	0.4	0.5
Wheeze or whistling in the chest in last year	0.4	0.7	5.6	-0.3	0.1	-0.2	-1.3	-0.1	-0.0	-1.5	-0.4	-0.1	0.7	-0.3	0.9	-0.2	-0.2	-2.4	1.8	1.6	0.0	0.2	-0.3	-0.6	0.5	-0.2	-0.3
Pulse wave peak to peak time	0.4	0.4	1.7	1.3	0.5	0.8	0.8	0.6	0.1	-0.9	0.3	0.4	0.5	0.4	1.0	0.6	0.4	0.2	0.7	1.1	0.7	0.5	-0.3	0.3	0.7	0.6	0.8
Emphysema/chronic bronchitis	0.4	0.5	1.8	-0.9	-0.6	-0.5	-1.0	-0.7	-0.5	-0.3	-0.2	-0.8	-0.1	-0.9	-0.2	-0.6	-0.9	-1.4	0.5	0.8	-0.7	-0.9	0.1	-0.9	-0.2	-0.7	-0.6
Migraine (self-reported)	0.4	0.5	2.9	0.5	0.8	0.6	0.9	0.8	1.7	-0.3	0.7	0.8	-0.7	0.7	0.5	1.1	0.9	-0.7	0.6	0.5	0.9	0.3	0.2	0.4	0.3	0.8	0.4
Overall health rating	0.4	0.9	3.4	-0.7	-0.8	-0.4	-0.9	-0.5	-1.5	1.8	-0.9	-0.6	-0.8	-0.8	-1.4	-0.9	-0.6	1.2	-1.6	-1.4	-0.7	-0.2	0.3	0.0	-0.5	-0.5	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	3.0	-1.7	-0.4	-0.6	-1.1	-0.3	-1.4	1.4	-0.7	-0.4	-0.1	-0.5	-1.4	-0.4	-0.5	0.0	-0.6	-0.7	-0.4	-0.3	-0.0	-0.1	-0.6	-0.4	-0.6
Asthma (self-reported)	0.4	0.7	3.2	-0.0	-0.3	-0.5	-1.4	-0.5	-0.1	-1.4	-0.7	-0.6	0.1	-0.8	0.7	-0.8	-0.7	-1.1	1.6	1.8	-0.5	-0.2	-1.1	-1.1	-0.2	-0.7	-0.5
Financial situation satisfaction	0.4	0.5	2.4	0.5	0.7	0.6	1.2	0.5	1.2	-0.1	0.7	0.6	0.2	0.6	0.3	0.5	0.6	-1.6	0.8	0.8	0.6	0.1	0.5	-0.2	1.0	0.3	0.5
Vascular/heart problems diagnosed by doctor	0.4	1.0	5.7	1.0	0.6	0.3	-0.0	0.4	1.4	-2.4	0.5	0.4	1.2	0.4	2.1	0.8	0.3	-0.9	1.8	1.6	0.5	0.3	-0.7	-0.5	0.1	0.2	0.2
Cholesterol lowering medication	0.4	0.6	2.8	0.3	0.0	0.2	0.7	0.3	1.1	0.5	-0.2	0.4	-1.2	0.4	-1.4	0.4	0.4	1.7	-1.7	-1.1	0.2	0.2	0.4	0.9	0.2	0.4	0.3
Heart disease (siblings)	0.4	0.5	2.5	0.5	-0.6	-0.5	-0.8	-0.6	1.6	-0.8	-0.2	-0.7	-0.1	-0.6	1.0	-0.6	-0.6	0.5	0.3	1.3	-0.6	-0.7	-1.3	-0.6	-0.5	-0.7	-0.6
Impedance of whole body	0.4	2.0	9.2	1.1	1.1	0.9	-0.0	0.9	3.0	-2.6	1.7	0.9	0.7	1.1	2.5	1.0	0.6	-1.5	2.0	2.3	1.1	0.8	-0.7	-0.8	1.2	0.8	0.7
Depression (Nagel 2018)	0.3	0.4	2.4	0.2	0.2	0.4	-0.2	0.4	-0.7	1.1	-0.8	0.2	-0.2	-0.1	-0.4	0.6	0.2	0.9	-0.8	-1.6	0.4	0.6	0.6	1.2	0.3	0.7	0.7
Neuroticism (Nagel 2018)	0.3	0.8	4.7	2.2	0.5	0.8	0.7	0.8	0.3	0.7	0.6	0.8	1.0	0.6	0.9	0.9	0.7	1.8	-0.6	-0.5	0.8	0.8	-0.5	1.0	0.6	0.8	0.9
Reaction Time	0.3	0.6	4.4	0.4	0.1	0.2	1.0	0.2	-0.7	2.0	-0.1	0.3	-0.1	0.3	-1.0	0.2	0.2	2.1	-1.4	-1.3	0.1	0.3	-0.1	0.4	-0.1	0.3	0.1
Rheumatoid Arthritis	0.3	0.5	2.2	1.0	-0.5	-0.3	-0.9	-0.7	-0.8	-0.2	-1.5	-0.5	1.0	-0.8	-0.8	-0.7	-0.5	0.4	0.4	0.5	-0.6	-0.1	-0.8	-0.5	-0.3	-0.7	-0.3
Cardiovascular Disease	0.3	0.9	5.3	-0.3	-0.6	-0.3	0.3	-0.2	-1.6	1.7	-0.6	-0.2	-1.0	-0.2	-2.2	-0.5	-0.1	1.1	-2.3	-1.6	-0.3	-0.2	0.5	0.9	-0.2	-0.0	-0.3
Lung FEV1/FVC ratio	0.3	1.3	7.2	-1.0	-0.8	-0.5	-0.2	-0.7	-1.8	2.7	-0.6	-0.7	-0.9	-0.6	-1.8	-0.9	-0.6	2.3	-1.7	-1.6	-0.9	-0.2	0.2	0.4	-1.0	-0.5	-0.5
Hand grip strength (left)	0.3	0.8	2.0	-1.4	-0.7	-1.1	-1.3	-0.9	-1.0	0.4	-0.5	-1.0	1.4	-1.0	-0.3	-0.7	-0.9	-0.9	0.5	0.1	-1.0	-0.9	0.1	-0.5	-1.1	-0.9	-1.2
Hearing difficulty/problems: Yes	0.3	0.5	2.1	-0.7	-0.4	-0.4	-1.4	-0.5	-1.4	1.2	-0.4	-0.6	-0.5	-0.7	-1.5	-0.7	-0.7	0.8	-0.2	-0.8	-0.6	-0.4	-0.1	-0.0	-0.6	-0.5	-0.6
Stomach or abdominal pain in last month	0.3	0.3	3.0	-0.5	-0.3	0.0	-1.2	-0.1	0.6	0.3	-0.3	-0.3	-1.7	-0.4	-1.1	-0.2	-0.3	-0.3	-0.8	-0.4	-0.1	-0.3	0.4	0.7	0.1	-0.1	-0.1
Qualifications: None of the above	0.3	0.7	10.9	1.0	0.5	0.7	-0.3	0.2	-0.1	-0.7	1.2	0.3	3.3	0.3	0.4	0.2	0.3	0.1	1.0	1.3	0.3	0.3	-0.4	-0.4	0.4	0.1	0.4
Diabetes (self-reported)	0.3	0.4	1.5	-0.3	-0.6	-0.3	-0.7	-0.7	0.6	-0.9	-1.0	-0.6	-1.2	-0.8	-0.4	-0.5	-0.6	-1.2	0.1	0.2	-0.6	-0.7	0.1	-0.4	0.1	-0.7	-0.5
Medication: Simvastatin	0.3	0.4	1.2	-0.9	-0.5	-0.6	-0.9	-0.7	0.8	-0.5	-0.6	-0.6	-0.3	-0.6	-0.0	-0.6	-0.6	-1.1	0.5	0.7	-0.6	-0.9	-0.4	-0.6	-0.1	-0.6	-0.7
Impedance of arm (right)	0.3	1.3	7.0	1.3	0.8	0.8	0.3	0.7	2.6	-2.0	1.2	0.7	-0.1	0.9	2.1	0.7	0.5	-0.8	1.4	1.8	0.9	0.7	-0.8	-0.5	1.0	0.6	0.6
Noisy workplace	0.3	0.3	1.6	-0.7	-0.6	-0.8	-0.5	-0.6	-1.3	0.0	-0.6	-0.5	0.6	-0.6	-0.3	-0.7	-0.7	-0.4	-0.2	0.0	-0.7	-0.5	-0.5	-0.4	-0.8	-0.7	-0.6
Mouth/teeth dental problems: Dentures	0.3	0.6	6.9	-0.8	0.0	-0.3	-0.5	-0.2	-2.6	0.7	-1.3	-0.1	1.2	-0.3	-0.9	-0.4	-0.2	0.1	0.1	-0.9	-0.3	0.3	0.2	-0.3	-0.3	-0.3	-0.3
Length of working week for main job	0.3	0.3	1.5	-1.0	-0.2	-0.2	-0.3	-0.1	-1.0	1.2	-0.3	-0.0	-0.5	-0.1	-0.7	-0.4	0.1	0.2	-1.0	-1.2	-0.2	-0.1	0.9	0.4	-0.0	-0.1	-0.3
Hair/balding pattern: Pattern 4	0.3	0.8	2.4	0.8	0.3	0.7	1.0	0.6	-1.4	0.6	0.6	0.6	0.4	0.7	-1.4	0.6	0.6	0.6	-1.4	-1.5	0.5	0.7	1.4	1.2	0.5	0.8	0.7
Peak expiratory flow (PEF)	0.3	0.7	6.2	-0.3	0.5	0.3	-0.4	0.3	1.9	-1.2	0.1	0.1	1.0	0.2	0.4	0.5	0.1	-2.5	1.2	1.2	0.4	0.3	0.7	0.1	0.9	0.3	0.3
Loud music exposure frequency	0.3	0.3	2.0	-1.0	-0.3	-0.7	-0.3	-0.3	-0.7	-0.3	-0.3	-0.4	0.2	-0.3	0.7	-0.3	-0.2	-1.4	0.5	0.5	-0.3	-0.5	-0.2	-0.6	-0.6	-0.4	-0.8
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	3.9	0.4	0.6	0.2	0.6	0.5	1.2	-1.0	0.1	0.4	-2.0	0.5	-0.1	0.3	0.4	-1.1	0.9	0.5	0.6	0.4	0.1	0.2	0.6	0.5	0.3
Medication: Paracetamol	0.3	0.5	1.5	0.2	-0.5	-0.5	-0.7	-0.4	1.1	-0.9	1.1	-0.4	-1.1	-0.1	0.5	-0.5	-0.4	0.3	-0.2	1.2	-0.3	-0.7	-0.9	-0.5	-0.7	-0.5	-0.9
Number of full brothers	0.3	0.4	1.1	0.5	0.7	0.9	0.6	0.8	-0.4	-0.1	0.1	0.6	0.5	0.6	-0.3	0.7	0.5	0.2	-0.1	-0.2	0.8	0.7	0.9	0.7	0.8	0.9	1.0
Shortness of breath walking on level ground	0.3	0.4	2.8	0.4	-0.3	-0.1	-0.5	-0.1	-1.6	0.9	0.2	-0.0	1.3	-0.1	0.1	-0.2	-0.3	1.7	-0.8	-0.8	-0.2	0.3	-0.4	-0.1	-0.1	-0.1	-0.2
Medication: Blood pressure	0.3	0.5	3.6	-0.9	-0.6	-0.5	-0.2	-0.7	-1.0	1.9	-1.1	-0.7	0.1	-0.8	-0.9	-1.1	-0.5	-0.2	-0.2	-0.5	-0.8	-0.5	0.1	-0.4	-0.3	-0.6	-0.6
Medication: Allopurinol	0.3	0.4	1.1	1.0	0.8	0.5	1.1	0.7	0.3	0.9	0.3	0.8	0.7	0.8	-0.2	0.6	0.8	0.6	0.1	-0.0	0.7	1.0	0.3	0.3	0.7	0.6	0.6
Had major operations	0.3	0.4	2.0	0.1	-0.2	-0.0	-0.2	-0.4	1.4	-0.6	0.0	-0.4	-0.4	-0.4	0.6	-0.6	-0.4	-0.9	1.0	1.3	-0.4	-0.6	-0.3	-0.9	0.1	-0.5	-0.1
Smoking status: Previous	0.3	0.4	2.3	-0.7	-0.6	-1.1	-0.4	-0.5	-1.5	0.6	-0.1	-0.5	0.9	-0.5	-0.1	-0.5	-0.7	0.6	-0.6	-0.4	-0.5	-0.2	-0.3	-0.4	-1.0	-0.3	-0.8
Mood swings	0.3	0.5	2.4	-0.3	-0.6	-0.4	-0.4	-0.3	-1.5	1.4	-0.4	-0.3	0.0	-0.4	-0.7	-0.3	-0.3	0.5	-1.5	-1.3	-0.4	-0.4	0.3	0.6	-0.4	-0.3	-0.4
Long-standing illness, disability or infirmity	0.3	0.4	2.3	1.5	0.5	0.6	0.1	0.7	-0.1	-0.3	0.3	0.6	-0.0	0.4	0.8	0.4	0.6	0.9	0.4	0.3	0.7	1.0	-0.4	0.4	0.8	0.7	0.8
Osteoporosis (self-reported)	0.3	0.4	2.1	-0.4	-0.4	-0.6	-1.4	-0.3	-1.4	-0.1	-1.5	-0.4	-0.6	-0.7	-0.3	-0.2	-0.4	-0.2	-0.3	-0.8	-0.3	0.2	0.1	0.3	-0.5	-0.2	-0.5
Guilty feelings	0.3	0.5	2.3	0.8	0.4	0.3	-0.5	0.6	-1.5	0.4	-0.4	0.5	1.5	0.2	0.1	0.9	0.4	0.7	-0.4	-1.1	0.6	0.8	0.6	1.1	0.4	0.7	0.5
Eye problems/disorders: Glaucoma	0.3	0.3	0.6	0.6	0.7	0.7	0.5	0.7	0.8	0.3	0.7	0.5	-0.1	0.5	0.6	0.7	0.4	0.4	0.8	0.2	0.6	0.6	0.0	0.4	0.8	0.7	0.6
Medication: Blood pressure	0.3	0.6	5.4	-0.2	0.0	0.1	0.1	0.1	-1.2	1.2	-0.2	-0.0	-1.2	0.0	-0.9	-0.2	0.2	2.3	-0.9	-1.3	-0.0	0.2	0.1	0.7	-0.4	0.2	0.1
Average weekly beer plus cider intake	0.3	0.4	2.6	-0.5	-0.0	0.3	0.2	0.3	-0.6	1.4	1.1	0.4	0.9	0.3	-0.3	0.4	0.1	0.5	-1.6	-0.9	0.2	0.1	0.5	0.2	0.0	0.2	-0.0
Ever had prostate specific antigen (PSA) test	0.3	0.3	2.1	-0.3	-0.1	-0.6	-0.2	-0.3	1.4	-0.5	-0.6	-0.4	-1.3	-0.3	0.3	-0.3	-0.5	-0.5	0.8	0.8	-0.3	-0.4	-0.6	-0.6	-0.4	-0.3	-0.5
Commuting to job workplace: Cycle	0.3	0.4	1.8	-0.7	0.2	-0.1	0.1	0.3	-1.0	0.5	-0.5	0.1	-0.7	0.3	-1.3	0.2	0.4	-0.4	-0.5	-1.3	0.2	0.3	1.1	0.8	0.2	0.4	0.1
Alcohol drinker status: Previous	0.3	0.4	1.3	0.6	0.7	0.2	0.4	0.5	1.1	-0.7	-0.0	0.6	1.0	0.7	0.2	0.5	0.7	-1.1	0.9	0.7	0.5	0.6	0.3	0.1	0.5	0.3	0.3
Depressed Affect (Nagel 2018)	0.2	0.4	1.3	1.1	0.3	0.6	0.1	0.4	-0.7	1.0	0.4	0.5	0.9	0.3	0.3	0.4	0.4	1.1	-0.6	-1.0	0.4	0.4	0.2	0.9	0.4	0.5	0.5
Ovarian Cancer	0.2	0.3	1.1	-0.8	-0.3	-0.5	-0.9	-0.5	-0.3	0.0	-0.3	-0.4	-1.1	-0.3	-0.6	-0.6	-0.3	-0.8	-0.2	-0.6	-0.5	-0.2	0.5	-0.2	-0.2	-0.5	-0.5
Body Mass Index (BMI) (2010)	0.2	0.3	1.4	-0.9	-0.1	-0.3	-1.2	-0.2	-1.1	-1.0	-0.4	-0.2	-0.7	-0.1	-0.8	-0.4	-0.2	-1.0	0.4	0.6	-0.2	-0.2	0.2	-0.0	-0.6	-0.3	-0.4
LDL Cholesterol	0.2	0.4	1.7	-0.4	-0.6	-0.5	-0.6	-0.5	-0.3	-0.3	-0.9	-0.4	-1.3	-0.4	-0.6	-0.4	-0.5	0.7	-0.8	-0.6	-0.5	-0.3	-0.7	-0.3	-1.0	-0.6	-0.7
Primary Biliary Cirrhosis	0.2	0.3	2.4	1.2	-0.3	0.1	-0.1	-0.3	0.7	-1.5	0.1	-0.3	-0.1	-0.1	-0.4	-0.2	-0.2	0.4	0.0	1.0	-0.2	-0.5	-0.6	-0.2	-0.5	-0.2	-0.1
Type 2 Diabetes (T2D) (2012)	0.2	0.2	2.1	0.1	-0.1	0.3	-0.2	-0.0	0.7	0.1	0.3	-0.1	-1.4	-0.1	-0.5	0.2	-0.3	1.0	-0.6	-0.4	-0.0	-0.5	-0.2	-0.2	-0.0	0.0	0.3
Waist Hip Ratio (WHR)	0.2	1.0	15.9	-1.2	0.1	-0.2	-0.7	-0.1	0.0	-1.2	-0.7	-0.0	-1.4	-0.2	-0.4	-0.1	-0.0	-4.0	0.7	0.1	0.1	-0.1	1.1	0.2	0.6	0.0	-0.3
Systolic Blood Pressure	0.2	1.2	5.1	-2.1	-0.7	-0.7	-0.2	-0.5	-1.0	2.3	-1.3	-0.4	-2.2	-0.7	-1.2	-0.6	-0.5	-1.0	-1.6	-1.9	-0.5	-0.8	0.6	-0.2	0.0	-0.4	-0.5
Smoking Status	0.2	0.5	5.6	-0.5	0.0	-0.3	-0.0	0.1	-2.4	0.9	-0.0	0.1	2.2	0.0	0.4	0.1	0.0	0.0	-0.4	-0.8	0.1	0.7	0.2	-0.1	0.1	0.1	0.1
Allergy or Eczema	0.2	0.5	5.3	-0.9	0.3	-0.1	-1.0	-0.1	0.3	-1.2	-0.7	-0.0	-0.2	-0.1	-0.7	-0.2	0.0	-2.3	1.2	0.7	0.0	0.1	0.7	-0.2	0.2	-0.1	-0.3
Lung FVC	0.2	0.9	3.2	-1.8	-1.1	-1.2	-1.0	-1.0	0.5	1.1	-0.3	-1.0	0.5	-1.0	0.5	-0.6	-1.1	-0.8	-0.7	-0.7	-1.0	-1.4	-0.0	-0.7	-1.1	-0.9	-1.1
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	2.8	-0.8	0.2	-0.0	-0.8	0.3	-1.7	0.6	0.1	0.4	0.5	0.1	-0.1	-0.1	0.3	0.7	0.0	-0.3	0.3	0.8	0.0	0.1	-0.2	0.2	-0.2
Systolic blood pressure, automated reading	0.2	0.5	2.0	-1.0	0.1	0.1	0.0	0.2	-1.1	1.3	-0.9	0.2	-1.2	-0.0	-1.3	-0.0	0.2	-0.1	-0.8	-1.4	0.1	0.2	0.7	0.3	0.2	0.2	0.1
Pack years adult smoking proportion	0.2	0.4	1.1	-0.5	-0.9	-0.5	0.0	-0.8	-1.1	0.4	-0.1	-0.8	-0.2	-0.7	-0.2	-0.8	-0.7	-0.1	-0.7	-0.2	-0.8	-1.0	-0.1	-0.7	-0.1	-0.7	-0.3
Current tobacco smoking	0.2	0.3	1.7	-0.5	0.4	0.3	-0.2	0.3	-1.3	0.5	0.1	0.3	1.2	0.2	0.7	0.2	0.3	-1.2	0.4	-0.2	0.3	0.7	0.5	0.1	0.6	0.3	0.5
Taking other prescription medications	0.2	0.4	1.3	-0.1	0.7	0.6	-0.4	0.7	-0.9	0.9	-0.2	0.8	0.0	0.4	-0.7	0.4	0.6	0.7	-0.1	-0.7	0.7	1.2	0.5	0.6	0.6	0.7	0.6
Qualifications: CSEs or equivalent	0.2	0.3	1.6	-0.3	-0.7	-0.3	0.2	-0.3	-1.1	0.4	-0.3	-0.4	-0.7	-0.4	-0.2	-0.1	-0.4	-0.2	-1.2	-1.0	-0.4	-0.6	0.4	0.4	0.2	-0.3	-0.1
Medication: Atenolol	0.2	0.2	1.0	0.1	0.6	0.0	0.4	0.4	0.1	1.0	0.0	0.5	0.5	0.5	0.1	0.4	0.6	0.5	0.4	-0.6	0.4	0.7	0.4	0.4	-0.2	0.4	0.1
Medication: Levothyroxine sodium	0.2	0.3	1.8	-0.6	-0.5	0.1	-0.2	-0.2	-1.1	0.9	-0.1	-0.2	-0.5	-0.4	-0.8	-0.2	-0.1	0.0	-1.1	-1.3	-0.2	0.1	0.8	0.7	0.3	0.0	0.2
Waist circumference	0.2	0.8	4.2	-0.3	-0.7	-0.7	-0.8	-0.8	0.0	-1.1	-1.4	-0.8	-2.0	-1.0	-0.1	-1.0	-0.5	-1.5	0.9	1.0	-0.7	-0.6	-0.6	-0.8	-0.3	-0.9	-0.9
Had other major operations	0.2	0.2	1.0	1.0	0.2	0.2	0.4	0.4	0.2	0.2	-0.1	0.4	-0.8	0.3	-0.1	0.2	0.4	1.0	-0.3	0.1	0.3	0.7	-0.5	0.1	0.2	0.3	0.2
Allergy	0.2	0.4	2.7	0.6	-0.4	0.1	1.6	-0.1	0.4	0.3	0.7	-0.0	-0.4	0.3	0.7	-0.2	0.0	1.7	-1.2	-0.5	-0.1	-0.3	-0.8	-0.4	-0.1	-0.1	0.1
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	2.1	1.5	-0.2	-0.2	0.2	-0.3	-0.2	-0.9	-0.1	-0.2	0.4	-0.1	0.3	-0.3	-0.2	0.6	0.5	0.9	-0.2	-0.3	-0.9	-0.5	0.2	-0.3	0.1
Hip circumference	0.2	0.7	1.9	-0.0	-0.8	-0.9	-0.7	-0.9	0.0	-0.6	-0.9	-0.9	-1.4	-1.0	0.3	-1.0	-0.7	-0.3	0.8	1.2	-0.9	-0.7	-1.2	-1.0	-0.7	-1.0	-1.0
Worrier / anxious feelings	0.2	0.3	2.2	1.5	-0.3	0.0	1.2	-0.0	1.0	-0.1	-0.0	-0.1	-0.1	-0.1	0.2	-0.1	-0.0	1.1	-0.7	0.1	0.0	-0.1	-1.0	0.1	-0.0	-0.1	0.2
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	5.5	-1.4	-0.5	-0.7	-0.7	-0.6	1.5	-0.0	-0.2	-0.7	0.1	-0.7	0.2	-0.3	-0.7	-2.4	0.4	0.7	-0.5	-0.9	0.2	-0.4	-0.1	-0.6	-0.8
Standing height	0.2	1.7	12.4	-0.6	0.5	0.2	0.3	0.1	1.7	-1.6	0.8	0.0	0.7	0.1	2.4	0.2	0.3	-3.5	2.9	2.5	0.4	-0.2	-0.6	-0.9	0.8	0.0	0.1
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	1.6	0.5	0.3	0.1	0.2	0.4	0.6	-0.2	1.3	0.4	0.5	0.7	0.1	0.4	0.4	0.8	-0.2	0.4	0.4	0.2	-0.1	0.3	-0.4	0.3	-0.1
Gout (self-reported)	0.2	0.2	1.4	0.3	0.3	0.0	0.4	0.4	-0.2	1.0	-0.4	0.3	0.6	0.2	-0.8	0.3	0.2	1.2	-0.5	-0.7	0.2	0.7	0.2	0.5	-0.1	0.3	0.1
Medication: Ventolin 100micrograms inhaler	0.2	0.2	1.5	0.6	0.3	0.2	-0.0	0.2	0.2	-1.2	-0.5	0.3	-0.3	0.1	0.3	0.1	0.2	-0.9	0.8	0.9	0.3	0.4	-0.4	-0.5	0.7	0.1	0.1
Medication for pain relief, constipation, heartburn	0.2	0.3	2.6	-1.1	0.1	-0.0	0.7	-0.2	0.1	0.2	-0.7	-0.2	-0.5	-0.2	0.1	0.1	-0.1	-1.6	1.0	-0.1	-0.2	-0.3	0.4	-0.4	0.4	-0.2	0.3
Medication: Omeprazole	0.2	0.3	1.2	1.0	0.3	0.6	0.0	0.3	0.6	-0.5	0.3	0.4	0.6	0.3	0.7	0.2	0.3	-0.1	0.6	1.1	0.4	0.6	-0.5	-0.3	0.7	0.3	0.6
Mean time to correctly identify matches	0.2	0.3	3.3	0.3	0.0	-0.1	0.6	-0.1	-0.6	1.2	-0.5	0.1	-0.3	0.1	-0.8	-0.2	0.1	1.8	-0.6	-0.8	-0.1	0.2	-0.4	-0.1	-0.2	-0.1	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	1.6	-0.0	0.3	0.1	-0.9	0.3	-0.9	-0.5	0.3	0.3	1.3	0.3	-0.7	0.3	0.0	-0.9	0.2	0.2	0.3	0.7	0.7	0.2	0.3	0.4	0.2
Medication: Aspirin	0.2	0.3	0.6	0.8	0.7	0.6	-0.0	0.6	-0.4	0.0	0.7	0.7	0.1	0.7	-0.2	0.4	0.6	0.7	0.3	0.3	0.6	0.6	-0.1	0.6	0.5	0.5	0.4
Medication for cholesterol	0.2	0.3	1.7	0.3	-0.0	-0.1	-0.3	0.1	0.4	-0.9	0.4	0.1	0.9	-0.0	1.3	0.2	-0.0	-1.0	0.7	1.1	0.1	-0.1	-0.5	-0.6	-0.1	-0.1	-0.4
Mineral and other dietary supplements	0.2	0.3	2.7	-0.7	-0.0	0.5	-0.2	0.3	0.7	0.2	0.8	0.3	-0.4	0.2	-0.2	0.2	0.2	-1.6	-0.6	0.2	0.2	-0.3	1.1	0.2	0.4	0.2	0.2
Osteoarthritis (self-reported)	0.2	0.2	2.3	0.7	-0.3	0.1	-0.1	-0.3	-0.1	-0.3	0.1	-0.3	0.4	-0.1	0.6	-0.5	-0.3	1.5	-0.2	0.0	-0.3	0.1	-1.0	-0.5	-0.1	-0.3	0.0
Medication: Aspirin	0.2	0.2	0.6	0.8	0.6	0.6	-0.2	0.5	-0.5	0.2	0.6	0.6	-0.1	0.6	-0.5	0.2	0.5	0.7	0.1	0.2	0.5	0.6	0.1	0.7	0.5	0.5	0.5
Smoking status: Current	0.2	0.3	1.5	-0.4	0.4	0.3	-0.2	0.4	-0.7	0.4	0.1	0.3	1.2	0.2	1.0	0.3	0.3	-1.1	0.6	0.1	0.4	0.7	0.2	-0.2	0.7	0.2	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	1.4	-0.9	-0.7	-0.8	-1.0	-0.9	0.2	0.4	0.3	-0.9	0.3	-0.7	-0.4	-1.0	-0.9	-0.5	0.1	0.2	-1.0	-1.2	0.2	-0.6	-0.6	-1.0	-1.2
Number of self-reported non-cancer illnesses	0.2	0.4	1.2	0.3	0.7	0.7	0.3	0.6	-0.5	0.6	0.8	0.7	0.4	0.9	-0.9	0.1	0.7	0.3	-0.2	-0.2	0.6	0.8	0.6	0.3	1.1	0.6	0.8
Mother’s age at death	0.2	0.3	2.3	0.4	0.0	-0.1	-0.6	-0.1	-1.5	0.8	-0.0	-0.0	-0.3	-0.0	-0.2	-0.3	-0.1	1.5	-0.2	-0.6	-0.1	0.4	-0.4	0.3	-0.6	-0.1	-0.2
Commuting to job workplace: Public transport	0.2	0.2	1.8	-0.0	-0.2	0.2	0.1	-0.3	1.4	-0.7	0.0	-0.3	-0.2	-0.2	-0.0	-0.4	-0.3	-0.3	0.3	0.6	-0.3	-0.4	0.0	-0.7	0.6	-0.3	0.1
Leg fat percentage (left)	0.2	0.6	3.2	-0.1	-0.5	-0.5	-0.9	-0.6	0.5	-1.8	-0.6	-0.6	-1.5	-0.5	-0.0	-1.0	-0.6	-0.6	0.8	1.2	-0.6	-0.5	-0.7	-1.1	-0.4	-0.8	-0.8
Irritability	0.2	0.3	1.6	-0.0	-0.5	-0.5	-0.3	-0.3	-1.3	0.0	-0.7	-0.4	0.7	-0.5	0.7	-0.3	-0.4	0.4	-0.3	0.1	-0.3	-0.3	-1.2	-0.2	-0.4	-0.3	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.9	0.9	0.7	0.6	0.1	0.5	0.2	0.5	0.9	0.4	0.2	0.4	0.5	0.5	0.6	-0.1	1.0	0.5	0.5	0.6	0.1	0.6	0.6	0.6	0.6
Ulcerative Colitis (UC)	0.1	0.2	2.9	0.4	0.0	0.2	0.3	0.1	0.4	0.3	-0.3	0.1	-1.7	0.1	-0.5	0.0	0.2	-0.2	-0.5	-0.5	0.1	-0.2	0.2	0.1	0.6	-0.0	0.4
Prostate Cancer	0.1	0.1	0.7	-0.2	0.1	-0.0	-0.4	0.1	0.7	0.7	0.3	0.1	-0.8	0.1	0.1	0.3	-0.1	-0.1	0.1	0.3	0.1	0.1	-0.3	-0.0	-0.3	0.2	0.2
Mean Putamen Volume	0.1	0.2	1.4	-0.4	0.1	-0.1	0.7	0.2	1.2	0.1	0.6	0.3	-0.0	0.5	-0.1	0.4	0.4	-0.5	-0.2	0.1	0.3	-0.1	0.1	-0.1	-0.3	0.2	-0.2
Triglycerides	0.1	0.2	0.5	-0.3	-0.5	-0.1	-0.7	-0.3	-0.3	-0.4	-0.3	-0.6	-0.7	-0.7	-0.4	-0.7	-0.5	-0.0	-0.3	0.2	-0.4	-0.5	-0.4	-0.6	-0.2	-0.6	-0.6
BMI	0.1	0.7	4.8	-0.8	-0.6	-0.3	-0.4	-0.4	-2.2	1.1	-1.0	-0.3	-1.4	-0.6	-1.6	-0.7	-0.2	0.4	-0.9	-0.8	-0.5	-0.2	0.3	0.5	-0.4	-0.4	-0.7
Height	0.1	2.4	13.3	-0.0	0.6	0.1	0.9	0.3	2.0	-1.9	0.7	0.4	1.3	0.4	3.3	0.6	0.5	-3.6	3.3	3.0	0.5	0.0	-1.3	-1.1	0.6	-0.0	0.2
Tanning	0.1	1.4	4.2	-1.6	-1.2	-1.7	-1.8	-1.2	-2.0	0.3	-1.6	-1.4	0.3	-1.5	0.5	-1.2	-1.5	0.1	0.2	0.1	-1.2	-0.8	-1.0	-0.9	-1.4	-1.0	-1.2
Number of treatments/medications taken	0.1	0.2	0.7	-0.4	-0.1	-0.2	-0.7	-0.2	-0.4	0.8	-0.5	-0.2	-0.4	-0.2	-0.6	-0.5	-0.2	0.9	-0.3	-0.5	-0.2	0.2	-0.1	0.0	-0.1	-0.1	-0.2
Medication: Co-codamol	0.1	0.1	0.5	-0.0	0.2	-0.0	-0.7	0.1	-0.5	0.2	0.1	0.2	-0.2	0.1	0.3	-0.1	0.1	0.1	0.3	0.6	0.2	0.2	-0.3	-0.0	0.0	0.0	-0.2
Leg fat-free mass (left)	0.1	0.3	1.3	-0.4	-0.0	0.2	0.5	0.1	-1.0	1.1	-0.3	0.1	-0.3	-0.1	-0.7	0.1	0.4	-0.9	-0.2	-0.3	0.1	0.2	0.8	0.9	0.4	0.2	0.3
Trunk fat percentage	0.1	0.2	1.2	0.7	0.0	0.2	-0.3	-0.0	0.9	-1.1	-0.0	-0.0	-1.1	0.0	0.1	-0.3	-0.0	-0.2	0.6	1.1	0.0	0.3	-0.3	-0.4	0.4	-0.2	-0.1
Townsend deprivation index at recruitment	0.1	0.1	0.6	-0.2	0.0	0.0	0.0	0.3	-0.3	0.6	0.5	0.2	0.5	0.2	-0.6	0.2	0.2	0.0	-0.8	-0.2	0.2	0.3	0.5	0.1	0.1	0.3	0.2
Fed-up feelings	0.1	0.2	1.4	1.0	0.1	0.0	0.4	0.1	0.2	-0.1	-0.1	0.0	0.1	-0.0	1.2	0.1	0.1	0.2	0.3	0.4	0.2	0.0	-0.8	0.2	-0.0	0.2	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.7	-0.1	0.6	0.4	-0.1	0.6	-0.7	-0.8	0.4	0.7	0.9	0.7	0.5	0.7	0.4	-0.3	-0.0	-0.2	0.7	0.7	0.5	0.4	0.7	0.6	0.4
Hayfever, allergic rhinitis or eczema	0.1	0.3	2.2	-0.7	0.0	-0.4	-1.1	-0.3	0.3	-0.9	-0.6	-0.2	0.0	-0.3	-0.5	-0.1	-0.2	-1.5	1.0	0.6	-0.2	-0.3	0.4	-0.0	-0.2	-0.3	-0.4
Sitting height	0.1	0.9	6.2	-0.5	0.4	0.1	0.6	0.3	0.9	-1.1	0.6	0.2	0.0	0.1	2.1	0.4	0.4	-2.5	1.7	1.8	0.5	-0.2	-0.5	-0.8	0.7	0.2	0.3
Body mass index (BMI)	0.1	0.3	2.0	-0.0	-0.6	-0.3	-0.3	-0.4	-0.8	0.4	-1.0	-0.4	-1.4	-0.6	-1.2	-0.6	-0.3	0.3	-0.8	-0.4	-0.5	-0.2	0.2	0.2	-0.3	-0.5	-0.5
Leg predicted mass (left)	0.1	0.3	1.6	-0.4	0.0	0.2	0.6	0.2	-1.1	1.2	-0.3	0.1	-0.4	-0.1	-0.8	0.1	0.5	-0.8	-0.4	-0.5	0.2	0.3	0.9	1.0	0.4	0.2	0.3
Trunk fat mass	0.1	0.3	1.6	0.4	-0.1	0.0	-0.3	-0.2	0.7	-1.0	-0.2	-0.2	-1.0	-0.2	0.2	-0.5	-0.1	-0.9	0.8	1.3	-0.1	-0.0	-0.3	-0.4	0.3	-0.3	-0.3
Past tobacco smoking	0.1	0.1	1.5	0.3	-0.0	0.5	-0.0	-0.1	0.8	-0.4	-0.4	-0.1	-1.2	-0.0	-0.6	-0.3	0.1	0.4	-0.0	0.2	-0.1	-0.5	-0.2	0.1	-0.0	-0.3	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.7	-0.1	-0.4	-0.3	-0.7	-0.3	0.5	0.8	-0.7	-0.4	-0.1	-0.6	-0.1	-0.1	-0.4	0.6	-0.6	-0.4	-0.3	-0.3	0.0	0.4	-0.5	-0.2	-0.2
Had menopause	0.1	0.1	0.8	-0.2	0.5	0.2	0.2	0.2	0.3	0.3	-0.5	0.3	-0.7	0.3	-0.9	-0.1	0.3	0.5	0.5	-0.3	0.1	0.6	0.1	-0.4	0.1	0.1	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.1	1.1	0.2	0.3	0.0	-0.1	0.3	-0.1	-0.8	0.5	0.4	0.2	0.4	1.1	0.4	0.2	0.1	0.1	0.3	0.4	0.4	-0.3	0.1	0.3	0.3	0.1
Arm fat percentage (right)	0.1	0.4	3.4	0.2	-0.6	-0.4	-0.7	-0.5	0.0	-0.5	-0.9	-0.5	-1.9	-0.6	-0.5	-0.8	-0.5	-0.0	0.0	0.6	-0.5	-0.2	-0.4	-0.4	-0.3	-0.6	-0.6
Birth weight of first child	0.1	0.1	0.9	-0.5	-0.5	-0.3	0.4	-0.1	-0.1	-0.4	0.5	-0.2	-0.8	-0.0	0.2	-0.3	0.0	-1.0	-0.6	-0.0	-0.1	-0.3	0.3	-0.2	-0.3	-0.2	-0.3
Blood clot in the leg (DVT)	0.1	0.2	0.9	0.6	0.5	0.3	-0.1	0.3	-0.1	0.3	0.6	0.2	0.2	0.2	0.5	0.3	0.3	-0.3	0.9	0.5	0.3	0.4	-0.1	0.4	0.4	0.3	0.4
Body fat percentage	0.1	0.4	2.1	0.3	-0.3	-0.2	-0.7	-0.4	0.7	-1.2	-0.5	-0.4	-1.4	-0.4	0.1	-0.7	-0.4	-0.4	0.7	1.2	-0.4	-0.2	-0.6	-0.9	-0.0	-0.6	-0.6
Leg fat percentage (right)	0.1	0.5	2.8	-0.1	-0.3	-0.4	-1.0	-0.5	0.3	-1.7	-0.7	-0.5	-1.3	-0.4	-0.0	-0.8	-0.5	-0.6	1.0	1.1	-0.5	-0.2	-0.7	-1.0	-0.3	-0.7	-0.8
Health satisfaction	0.1	0.1	1.1	0.8	-0.2	0.2	0.1	-0.1	0.2	0.2	0.3	-0.2	1.1	-0.2	-0.6	-0.2	-0.2	0.8	-0.2	0.4	-0.2	-0.1	0.1	-0.0	0.3	-0.1	0.2
Qualifications: College or University degree	0.1	0.3	1.0	-0.2	0.6	0.3	1.0	0.6	0.7	-0.2	-0.1	0.3	-0.8	0.5	-0.3	0.5	0.5	-0.7	0.3	-0.2	0.6	0.7	0.9	0.7	0.5	0.8	0.6
Whole body fat mass	0.1	0.3	1.6	-0.0	-0.4	-0.3	-0.6	-0.5	0.3	-0.9	-0.6	-0.5	-1.3	-0.5	0.0	-0.7	-0.4	-0.8	0.6	1.1	-0.4	-0.3	-0.5	-0.7	-0.1	-0.6	-0.6
Leg fat mass (right)	0.1	0.4	1.5	-0.4	-0.5	-0.5	-0.8	-0.6	-0.3	-0.9	-1.0	-0.6	-1.2	-0.7	-0.2	-0.8	-0.5	-0.9	0.7	0.8	-0.6	-0.4	-0.4	-0.7	-0.4	-0.7	-0.8
Pulse rate, automated reading	0.1	0.4	2.4	0.5	-0.7	-0.5	0.6	-0.5	0.9	1.1	-0.2	-0.6	-1.6	-0.6	0.6	-0.6	-0.5	0.6	-0.5	0.2	-0.5	-0.7	-1.0	-0.3	-0.2	-0.5	-0.2
Comparative height size at age 10	0.1	0.6	6.7	-1.9	0.2	-0.1	-0.5	-0.1	0.9	0.1	-0.0	-0.2	0.1	-0.2	0.6	0.1	-0.0	-2.6	1.1	0.7	0.0	-0.3	0.5	-0.2	-0.2	-0.2	-0.4
Family relationship satisfaction	0.1	0.2	0.7	0.5	-0.0	-0.2	0.1	-0.1	0.8	-0.6	0.5	0.1	-0.3	-0.0	0.6	-0.0	-0.2	-0.2	0.4	0.7	0.0	-0.2	-0.5	-0.9	-0.0	-0.2	-0.3
Leg fat-free mass (right)	0.1	0.3	1.8	-0.5	-0.1	0.2	0.7	0.1	-1.0	1.3	-0.3	0.0	-0.2	-0.2	-0.9	0.1	0.4	-0.9	-0.6	-0.6	0.1	0.1	1.1	1.0	0.4	0.1	0.3
Arm fat percentage (left)	0.1	0.2	2.4	0.4	-0.3	-0.1	-0.5	-0.2	0.3	-0.7	-0.6	-0.3	-1.5	-0.3	-0.3	-0.5	-0.2	-0.1	0.3	0.8	-0.3	0.0	-0.2	-0.3	0.0	-0.3	-0.3
Average weekly red wine intake	0.1	0.2	1.5	-0.2	0.3	-0.2	0.5	0.2	-0.0	-0.2	-0.1	0.2	-0.2	0.1	1.2	0.3	0.2	0.1	0.9	-0.3	0.3	0.3	-0.6	-0.2	-0.1	0.2	0.0
Loneliness, isolation	0.1	0.2	1.7	1.3	-0.1	0.3	0.4	-0.2	-0.2	0.4	-0.4	0.0	0.1	-0.1	0.8	-0.2	0.1	0.9	-0.2	-0.3	-0.1	-0.1	-0.4	0.1	0.5	-0.1	0.4
Diabetes diagnosed by doctor	0.1	0.2	1.3	0.3	-0.2	0.2	0.1	-0.1	0.3	-0.5	-0.7	-0.0	-1.1	-0.2	-0.3	-0.1	-0.1	-0.8	-0.3	-0.4	-0.1	-0.1	0.4	0.1	0.7	-0.1	0.0
Eye problems/disorders: Cataract	0.1	0.2	0.9	0.4	0.3	0.4	0.6	0.3	0.0	-0.3	-0.0	0.2	-0.0	0.1	0.9	0.2	0.3	-0.3	0.8	0.5	0.3	0.4	0.1	0.4	0.5	0.3	0.6
Leg predicted mass (right)	0.1	0.4	1.9	-0.4	-0.0	0.3	0.7	0.2	-1.0	1.4	-0.2	0.1	-0.2	-0.1	-0.9	0.2	0.5	-0.7	-0.6	-0.7	0.2	0.2	1.1	1.1	0.5	0.3	0.4
Pain type(s) experienced in last month: Hip pain	0.1	0.1	1.0	0.6	0.0	-0.1	0.1	-0.1	-0.5	-1.0	0.2	-0.0	0.8	0.1	-0.0	-0.4	0.3	0.2	0.6	0.4	-0.1	-0.0	-0.1	-0.4	-0.0	-0.2	-0.2
Medication: Paracetamol	0.1	0.2	1.0	-0.0	-0.0	-0.3	-0.7	0.0	0.9	-0.7	0.9	0.0	-0.7	0.1	0.4	-0.2	-0.0	-0.0	0.1	1.0	0.0	-0.1	-0.5	-0.2	-0.6	-0.1	-0.7
Ever smoked	0.1	0.2	1.1	-0.4	-0.3	-0.6	-0.2	-0.2	-0.5	1.0	-0.2	-0.2	1.0	-0.3	0.0	0.1	-0.4	-0.1	-0.5	-1.0	-0.2	0.2	0.6	0.0	-0.1	0.1	-0.0
Number of operations (self-reported)	0.1	0.2	0.9	0.2	-0.2	-0.1	-0.5	-0.3	0.4	0.5	-0.6	-0.3	-0.9	-0.4	-0.9	-0.4	-0.4	-0.3	-0.1	-0.3	-0.4	-0.1	0.3	-0.3	0.3	-0.4	-0.1
Ever depressed for a whole week	0.1	0.2	0.8	-0.6	-0.2	-0.4	-0.9	-0.2	0.7	0.5	-0.1	-0.3	-0.3	-0.5	0.3	-0.2	-0.5	-0.6	0.3	0.3	-0.3	-0.1	0.1	-0.3	-0.3	-0.2	-0.4
Unable to work because of sickness or disability	0.1	0.1	0.6	0.2	-0.2	-0.3	-0.7	-0.0	-0.3	0.4	-0.2	0.0	-0.8	-0.2	0.1	0.0	-0.2	0.5	-0.3	-0.1	-0.0	0.1	-0.4	0.1	-0.3	-0.0	-0.5
Pack years of smoking	0.1	0.2	0.8	-0.0	-0.5	-0.2	0.3	-0.5	-0.8	-0.0	0.4	-0.4	0.1	-0.3	0.4	-0.5	-0.3	0.1	0.0	0.3	-0.5	-0.7	-0.3	-0.9	0.1	-0.5	-0.1
Leg fat mass (left)	0.1	0.5	1.9	-0.4	-0.6	-0.5	-0.8	-0.6	-0.2	-0.8	-0.9	-0.6	-1.4	-0.7	-0.3	-0.9	-0.5	-0.8	0.5	0.7	-0.6	-0.5	-0.3	-0.7	-0.4	-0.8	-0.8
Heel T-Score	0.0	0.1	1.8	0.3	-0.0	-0.1	-0.1	0.2	0.3	-0.4	-0.5	-0.1	1.3	-0.2	0.7	0.6	-0.0	0.0	-0.1	-0.2	0.1	-0.0	-0.3	0.1	-0.1	0.1	-0.2
Hair Pigment	0.0	0.8	5.2	0.1	-0.4	-0.1	-0.2	-0.1	-1.3	1.3	-0.5	-0.1	-0.7	-0.1	-1.5	-0.1	0.1	2.3	-1.8	-1.8	-0.2	0.2	0.4	1.0	-0.2	0.1	-0.2
Weight	0.0	0.2	1.5	-0.3	-0.3	-0.2	-0.0	-0.3	0.1	-0.2	-0.6	-0.4	-1.0	-0.5	-0.2	-0.5	-0.1	-1.2	0.5	0.7	-0.3	-0.3	0.0	-0.2	0.1	-0.4	-0.3
Trunk fat-free mass	0.0	0.2	3.3	-0.7	0.2	0.1	0.5	0.1	-0.4	0.5	-0.1	-0.0	0.2	-0.2	0.1	0.1	0.4	-1.8	0.8	0.5	0.1	-0.1	0.4	0.2	0.4	0.0	0.1
Arm fat mass (right)	0.0	0.2	2.4	-0.1	-0.2	-0.1	-0.3	-0.2	-0.0	-0.2	-0.6	-0.2	-1.6	-0.4	-0.5	-0.4	-0.0	-0.6	0.2	0.5	-0.2	-0.0	0.1	0.1	0.0	-0.3	-0.3
Trunk predicted mass	0.0	0.3	3.7	-0.8	0.1	-0.0	0.5	-0.0	-0.3	0.4	-0.1	-0.1	0.1	-0.3	0.1	-0.0	0.3	-1.9	0.9	0.6	0.0	-0.2	0.3	0.1	0.3	-0.1	0.0
Arm fat-free mass (right)	0.0	0.2	2.1	-0.4	0.3	0.3	0.6	0.2	-0.2	0.6	0.1	0.2	0.5	0.0	-0.2	0.2	0.5	-1.4	0.5	0.2	0.3	0.1	0.8	0.5	0.6	0.2	0.3
Arm predicted mass (right)	0.0	0.2	1.7	-0.9	-0.2	-0.2	0.2	-0.2	-0.4	0.8	-0.4	-0.2	0.3	-0.4	-0.4	-0.2	0.1	-1.3	0.4	0.1	-0.2	-0.3	0.5	0.1	0.1	-0.2	-0.2
Whole body fat-free mass	0.0	0.2	2.0	-0.5	0.2	0.2	0.7	0.2	-0.6	0.8	-0.1	0.1	0.1	-0.1	-0.2	0.2	0.5	-1.4	0.4	0.1	0.2	0.1	0.7	0.6	0.5	0.2	0.3
Whole body water mass	0.0	0.2	1.8	-0.5	0.1	0.2	0.6	0.1	-0.5	0.8	-0.0	0.0	0.1	-0.1	-0.2	0.1	0.5	-1.3	0.4	0.2	0.2	0.0	0.6	0.6	0.5	0.1	0.2
Arm fat mass (left)	0.0	0.2	2.1	-0.1	-0.3	-0.2	-0.3	-0.3	0.1	-0.1	-0.6	-0.3	-1.4	-0.4	-0.5	-0.5	-0.1	-0.5	0.1	0.5	-0.3	-0.1	0.1	0.0	-0.0	-0.3	-0.4
Basal metabolic rate	0.0	0.2	2.2	-0.5	0.0	0.1	0.4	0.1	-0.5	0.6	-0.2	-0.0	-0.1	-0.2	-0.3	0.0	0.4	-1.5	0.4	0.3	0.1	-0.0	0.6	0.4	0.4	0.0	0.1
Arm fat-free mass (left)	0.0	0.2	1.3	-0.5	0.2	0.2	0.6	0.2	-0.2	0.8	-0.1	0.1	0.3	-0.0	-0.4	0.2	0.5	-1.1	0.4	0.1	0.2	0.1	0.7	0.5	0.3	0.1	0.2
Arm predicted mass (left)	0.0	0.1	1.2	-0.6	-0.0	-0.0	0.6	-0.1	-0.5	0.8	-0.1	-0.1	0.2	-0.2	-0.3	-0.2	0.3	-1.1	0.5	0.3	-0.1	-0.2	0.4	0.2	0.1	-0.1	-0.1

Hub : Genes

FANCG

Models

Trait associations