Best TWAS P=4.03e-21 · Best GWAS P=1.3e-24 conditioned to 3.85e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ZNF259 | 0.08 | 0.03 | enet | 6 | 0.03 | 1.2e-04 | -7.58 | 9.1 | 1.4e-19 | 0.01 | 0.91 | 0.00 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | SIDT2 | 0.11 | 0.00 | enet | 13 | 0.01 | 9.0e-02 | -2.79 | 9.1 | 7.8e-20 | 0.57 | 0.05 | 0.65 | FALSE |
| 3 | GTEx | Thyroid | PCSK7 | 0.12 | 0.03 | enet | 18 | 0.06 | 2.9e-05 | 9.07 | 5.5 | 4.5e-08 | 0.72 | 0.06 | 0.94 | FALSE |
| 4 | METSIM | Adipose | PAFAH1B2 | 0.07 | 0.02 | bslmm | 563 | 0.02 | 1.2e-04 | 2.68 | -7.8 | 6.4e-15 | -0.70 | 0.08 | 0.90 | FALSE |
| 5 | METSIM | Adipose | PCSK7 | 0.10 | 0.02 | bslmm | 541 | 0.06 | 7.5e-09 | -0.55 | 6.6 | 4.6e-11 | 0.66 | 0.06 | 0.92 | FALSE |
| 6 | YFS | Blood | SIK3 | 0.03 | 0.01 | enet | 20 | 0.02 | 4.7e-06 | 9.73 | -6.8 | 1.3e-11 | -0.78 | 0.02 | 0.98 | FALSE |
| 7 | The Cancer Genome Atlas | Colon Adenocarcinoma | SIDT2 | 0.11 | 0.00 | blup | 46 | 0.05 | 8.2e-04 | -2.85 | 6.2 | 4.4e-10 | 0.43 | 0.02 | 0.12 | FALSE |
| 8 | The Cancer Genome Atlas | Brain Lower Grade Glioma | SIDT2 | 0.08 | 0.01 | blup | 46 | 0.05 | 2.4e-06 | -3.09 | 6.4 | 2.0e-10 | 0.55 | 0.02 | 0.84 | FALSE |
| 9 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | ZNF259 | 0.04 | 0.03 | lasso | 3 | 0.02 | 8.4e-04 | -7.15 | 8.1 | 6.0e-16 | 0.09 | 0.19 | 0.09 | FALSE |
| 10 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | BUD13 | 0.08 | 0.00 | blup | 76 | 0.01 | 9.2e-02 | -0.18 | 5.2 | 1.5e-07 | 0.11 | 0.02 | 0.04 | FALSE |
| 11 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | SIDT2 | 0.16 | 0.08 | enet | 10 | 0.04 | 1.2e-02 | 9.59 | 9.4 | 4.0e-21 | 0.84 | 0.00 | 0.88 | TRUE |