Best TWAS P=3.05e-12 · Best GWAS P=2.06e-18 conditioned to 2.97e-08
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Caudate basal ganglia | FURIN | 0.39 | 0.09 | enet | 10 | 0.02 | 0.0660 | -6.8 | -6 | 1.7e-09 | 0.74 | 0.05 | 0.62 | FALSE |
2 | The Cancer Genome Atlas | Colon Adenocarcinoma | CRTC3 | 0.07 | 0.02 | blup | 78 | 0.03 | 0.0099 | 2.0 | -7 | 3.1e-12 | 0.65 | 0.02 | 0.48 | TRUE |