[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr16:511,080-1,976,867

Best TWAS P=1.87e-13 · Best GWAS P=1.46e-12 conditioned to 0.00988

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Mucosa TPSB2 0.41 0.24 enet 20 0.28 2.8e-19 4.8 -5.6 1.8e-08 -0.41 1.00 0.00 FALSE
2 GTEx Lung TPSB2 0.28 0.13 lasso 5 0.16 1.2e-12 5.2 -5.3 1.2e-07 -0.37 0.99 0.01 FALSE
3 GTEx Skin Not Sun Exposed Suprapubic CACNA1H 0.23 0.16 lasso 5 0.16 4.2e-09 7.1 -6.8 8.3e-12 -0.98 0.00 1.00 FALSE
4 GTEx Skin Sun Exposed Lower leg CACNA1H 0.22 0.21 lasso 1 0.20 8.8e-17 7.1 -7.1 1.5e-12 -1.00 0.00 1.00 FALSE
5 GTEx Skin Sun Exposed Lower leg TPSB2 0.16 0.14 enet 6 0.16 2.8e-13 5.2 -5.5 3.4e-08 -0.37 0.99 0.01 FALSE
6 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma TPSAB1 0.14 0.01 enet 11 0.10 1.6e-05 7.1 -5.5 4.4e-08 -0.72 0.00 0.95 FALSE
7 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma TPSB2 0.17 0.08 lasso 3 0.06 5.3e-04 7.1 -7.3 4.0e-13 -0.96 0.00 0.98 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma TPSB2 0.09 0.06 lasso 2 0.02 1.7e-02 5.2 -5.2 1.7e-07 -0.31 0.03 0.18 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma TPSB2 0.08 0.06 lasso 5 0.07 1.2e-08 5.2 -5.3 9.5e-08 -0.24 0.97 0.02 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TPSB2 0.10 0.09 lasso 3 0.09 8.6e-11 5.2 -5.5 3.4e-08 -0.28 0.99 0.01 FALSE
11 The Cancer Genome Atlas Pancreatic Adenocarcinoma TPSB2 0.12 0.01 enet 5 0.03 2.7e-02 5.2 -7.4 1.9e-13 -0.72 0.00 0.74 TRUE
12 The Cancer Genome Atlas Pancreatic Adenocarcinoma TPSD1 0.35 0.16 enet 23 0.17 1.1e-07 2.3 -5.8 5.3e-09 -0.18 0.03 0.95 FALSE
13 The Cancer Genome Atlas Soft Tissue Sarcoma TPSD1 0.11 0.07 lasso 3 0.09 3.2e-06 5.2 -5.3 8.7e-08 -0.30 0.01 0.97 FALSE