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chr15:84,151,637-86,990,983

Best TWAS P=1.67e-10 · Best GWAS P=8.89e-15 conditioned to 2e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	UBE2Q2P1	0.08	0.04	blup	382	0.05	2.3e-06	3.8	-5.6	2.6e-08	0.12	0.94	0.01	FALSE
2	CommonMind	Brain Pre-frontal Cortex	ZSCAN2	0.03	0.02	enet	5	0.02	9.7e-04	-6.3	5.7	1.0e-08	-0.08	0.01	0.99	FALSE
3	GTEx	Adipose Subcutaneous	WDR73	0.19	0.13	enet	13	0.16	3.5e-13	-6.3	6.0	1.5e-09	-0.01	0.00	1.00	FALSE
4	GTEx	Adipose Subcutaneous	RP11-182J1.16	0.23	0.03	enet	32	0.10	9.1e-09	-6.3	5.7	1.5e-08	-0.01	0.01	0.99	FALSE
5	GTEx	Adipose Visceral Omentum	CSPG4P11	0.14	0.07	enet	15	0.09	2.9e-05	-4.2	5.3	1.2e-07	-0.07	0.02	0.98	FALSE
6	GTEx	Artery Aorta	WDR73	0.16	0.12	lasso	5	0.12	2.9e-07	-6.3	6.2	5.4e-10	-0.07	0.01	0.99	FALSE
7	GTEx	Artery Tibial	WDR73	0.18	0.17	lasso	3	0.17	4.2e-13	-6.3	6.1	8.2e-10	-0.07	0.01	0.99	FALSE
8	GTEx	Artery Tibial	RP11-182J1.16	0.11	0.09	enet	14	0.08	4.1e-07	-4.2	5.4	8.3e-08	-0.06	0.06	0.93	FALSE
9	GTEx	Brain Cortex	WDR73	0.25	0.17	lasso	11	0.16	3.4e-05	-6.3	6.2	4.7e-10	-0.04	0.01	0.97	FALSE
10	GTEx	Brain Hippocampus	AC103965.1	0.26	0.12	lasso	11	0.20	2.1e-05	-6.3	5.7	9.4e-09	-0.11	0.03	0.92	FALSE
11	GTEx	Brain Hypothalamus	WDR73	0.24	0.04	lasso	8	0.00	4.0e-01	-6.3	5.3	9.9e-08	-0.01	0.02	0.79	FALSE
12	GTEx	Breast Mammary Tissue	WDR73	0.12	0.12	lasso	3	0.10	1.0e-05	-6.3	6.3	3.0e-10	-0.07	0.00	0.99	FALSE
13	GTEx	Breast Mammary Tissue	CSPG4P11	0.08	0.08	lasso	2	0.05	1.3e-03	-6.4	6.0	1.6e-09	-0.07	0.01	0.97	FALSE
14	GTEx	Breast Mammary Tissue (Male)	WDR73	0.02	0.00	enet	3	-0.01	5.9e-01	-6.3	6.3	3.2e-10	-0.03	0.02	0.40	FALSE
15	GTEx	Breast Mammary Tissue (Female)	CSPG4P11	0.17	0.15	enet	7	0.10	5.1e-04	-6.3	6.3	3.5e-10	-0.07	0.01	0.97	FALSE
16	GTEx	Cells Transformed fibroblasts	WDR73	0.26	0.20	lasso	8	0.18	1.4e-13	-6.3	5.3	9.0e-08	-0.04	0.01	0.99	FALSE
17	GTEx	Colon Sigmoid	WDR73	0.19	0.28	lasso	4	0.21	4.7e-08	-6.3	6.3	3.3e-10	-0.07	0.01	0.99	FALSE
18	GTEx	Colon Transverse	WDR73	0.18	0.15	enet	13	0.14	4.7e-07	-6.3	5.7	9.7e-09	-0.04	0.01	0.99	FALSE
19	GTEx	Esophagus Gastroesophageal Junction	WDR73	0.16	0.00	enet	8	0.05	5.8e-03	-6.3	5.2	2.2e-07	0.00	0.01	0.92	FALSE
20	GTEx	Esophagus Mucosa	RP11-182J1.16	0.20	0.05	lasso	5	0.10	1.8e-07	-4.4	5.2	1.8e-07	0.00	0.48	0.48	FALSE
21	GTEx	Esophagus Muscularis	RP11-182J1.16	0.12	0.10	lasso	8	0.11	4.5e-07	-4.2	5.6	2.4e-08	-0.06	0.02	0.98	FALSE
22	GTEx	Heart Atrial Appendage	AC103965.1	0.24	0.12	enet	24	0.14	7.2e-07	-5.2	6.4	1.7e-10	-0.05	0.08	0.92	TRUE
23	GTEx	Heart Atrial Appendage	RP11-182J1.16	0.24	0.20	lasso	8	0.13	2.6e-06	-6.3	6.0	2.0e-09	-0.05	0.01	0.99	FALSE
24	GTEx	Heart Atrial Appendage	CSPG4P11	0.12	0.08	lasso	5	0.10	4.3e-05	-4.2	5.4	7.4e-08	-0.05	0.05	0.94	FALSE
25	GTEx	Heart Left Ventricle	WDR73	0.11	0.07	lasso	5	0.06	2.4e-04	-6.3	6.0	1.6e-09	-0.05	0.01	0.97	FALSE
26	GTEx	Heart Left Ventricle	AC103965.1	0.16	0.13	enet	14	0.12	7.0e-07	-4.4	5.4	8.5e-08	-0.05	0.08	0.92	FALSE
27	GTEx	Lung	WDR73	0.12	0.08	lasso	8	0.08	1.3e-06	-6.3	5.2	2.4e-07	-0.05	0.01	0.99	FALSE
28	GTEx	Muscle Skeletal	WDR73	0.08	0.05	enet	11	0.07	1.5e-07	-6.3	6.3	2.4e-10	-0.08	0.00	1.00	FALSE
29	GTEx	Muscle Skeletal	RP11-182J1.16	0.10	0.03	enet	15	0.05	5.4e-06	-6.3	5.1	3.1e-07	0.00	0.01	0.98	FALSE
30	GTEx	Muscle Skeletal	RP11-182J1.14	0.10	0.05	lasso	5	0.04	4.4e-05	-4.4	-5.2	2.3e-07	0.08	0.92	0.04	FALSE
31	GTEx	Muscle Skeletal	CSPG4P11	0.14	0.07	lasso	5	0.08	1.4e-08	-6.3	5.7	1.5e-08	-0.03	0.01	0.99	FALSE
32	GTEx	Nerve Tibial	WDR73	0.34	0.29	lasso	7	0.29	1.7e-20	-6.3	5.9	2.9e-09	-0.07	0.01	0.99	FALSE
33	GTEx	Ovary	WDR73	0.36	0.23	lasso	7	0.30	5.4e-08	-6.3	5.5	3.4e-08	-0.02	0.01	0.98	FALSE
34	GTEx	Ovary	RP11-182J1.16	0.20	0.08	enet	14	0.15	1.4e-04	-5.2	5.5	3.4e-08	-0.04	0.02	0.94	FALSE
35	GTEx	Ovary	CSPG4P11	0.21	0.17	lasso	4	0.18	3.1e-05	-5.2	5.6	1.9e-08	-0.07	0.03	0.93	FALSE
36	GTEx	Pituitary	WDR73	0.19	0.07	lasso	8	0.07	7.9e-03	-6.3	6.1	1.0e-09	-0.06	0.01	0.94	FALSE
37	GTEx	Prostate	WDR73	0.29	0.25	enet	17	0.21	5.4e-06	-6.3	5.2	2.2e-07	-0.03	0.01	0.97	FALSE
38	GTEx	Skin Not Sun Exposed Suprapubic	AC103965.1	0.23	0.15	lasso	8	0.19	1.9e-10	-4.2	5.7	1.2e-08	-0.03	0.04	0.96	FALSE
39	GTEx	Skin Not Sun Exposed Suprapubic	RP11-182J1.16	0.10	0.01	enet	13	0.04	3.1e-03	-6.3	5.8	6.3e-09	-0.06	0.03	0.93	FALSE
40	GTEx	Skin Not Sun Exposed Suprapubic	CSPG4P11	0.29	0.07	enet	29	0.13	9.6e-08	-4.2	5.9	3.5e-09	-0.02	0.05	0.95	FALSE
41	GTEx	Skin Sun Exposed Lower leg	ZSCAN2	0.08	0.02	enet	13	0.03	1.4e-03	3.8	-5.2	2.0e-07	0.01	0.08	0.81	FALSE
42	GTEx	Skin Sun Exposed Lower leg	WDR73	0.08	0.04	lasso	8	0.05	3.4e-05	-6.3	5.3	9.2e-08	-0.04	0.01	0.99	FALSE
43	GTEx	Skin Sun Exposed Lower leg	RP11-182J1.16	0.09	0.04	enet	18	0.04	1.4e-04	-4.2	5.4	6.2e-08	-0.03	0.02	0.97	FALSE
44	GTEx	Skin Sun Exposed Lower leg	CSPG4P11	0.18	0.07	lasso	11	0.19	9.1e-16	-6.3	6.2	6.3e-10	-0.03	0.01	0.99	FALSE
45	GTEx	Testis	GOLGA6L4	0.49	0.21	enet	31	0.39	3.1e-18	-6.3	5.3	1.1e-07	0.03	0.00	1.00	FALSE
46	GTEx	Testis	RN7SL417P	0.09	0.08	lasso	3	0.08	3.1e-04	-4.2	-5.7	1.5e-08	0.06	0.01	0.96	FALSE
47	GTEx	Testis	RP11-158M2.3	0.20	0.22	lasso	5	0.20	2.1e-09	-5.8	5.4	6.2e-08	-0.64	0.89	0.11	TRUE
48	GTEx	Thyroid	ZSCAN2	0.06	0.03	lasso	2	0.03	2.9e-03	-5.0	-5.3	9.5e-08	0.10	0.15	0.51	FALSE
49	GTEx	Thyroid	WDR73	0.28	0.26	lasso	8	0.28	1.1e-21	-6.3	6.3	2.9e-10	-0.06	0.00	1.00	FALSE
50	The Cancer Genome Atlas	Breast Invasive Carcinoma	WDR73	0.07	0.02	enet	10	0.05	4.5e-11	-2.4	6.1	1.3e-09	-0.13	0.01	0.99	FALSE
51	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	WDR73	0.09	0.07	lasso	5	0.07	9.8e-09	-6.3	5.6	1.8e-08	-0.06	0.00	1.00	FALSE
52	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	WDR73	0.10	0.05	blup	40	0.07	7.0e-05	-6.3	5.4	8.2e-08	-0.07	0.01	0.98	FALSE
53	The Cancer Genome Atlas	Brain Lower Grade Glioma	AKAP13	0.06	0.00	blup	265	0.04	2.6e-05	-7.0	5.3	1.5e-07	-0.61	0.05	0.90	FALSE
54	The Cancer Genome Atlas	Brain Lower Grade Glioma	WDR73	0.20	0.20	lasso	7	0.26	1.8e-29	-6.3	5.2	1.6e-07	-0.04	0.01	0.99	FALSE
55	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ZSCAN2	0.05	0.01	blup	46	0.02	2.7e-02	-5.0	-5.9	3.5e-09	0.09	0.01	0.70	FALSE
56	The Cancer Genome Atlas	Lung Adenocarcinoma	WDR73	0.05	0.03	lasso	4	0.04	1.6e-05	-6.3	6.1	1.3e-09	-0.06	0.00	1.00	FALSE
57	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	WDR73	0.16	0.17	blup	40	0.19	4.3e-08	-6.3	6.2	5.0e-10	-0.08	0.01	0.99	FALSE
58	The Cancer Genome Atlas	Prostate Adenocarcinoma	WDR73	0.13	0.12	blup	40	0.14	4.7e-14	-6.3	5.8	6.0e-09	-0.11	0.00	1.00	FALSE