[Hub]/) : Traits : Blood Eosinophil Count :

chr17:55,730,637-58,837,937

Best TWAS P=3.52e-14 · Best GWAS P=3.14e-15 conditioned to 9.44e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RPS6KB1 0.04 0.00 bslmm 275 0.01 1.7e-02 3.2 7.6 3.5e-14 -0.67 0.03 0.82 TRUE
2 GTEx Adipose Subcutaneous SUPT4H1 0.07 0.08 lasso 2 0.07 2.5e-06 5.3 -5.3 1.1e-07 0.01 0.03 0.96 FALSE
3 GTEx Adipose Visceral Omentum SUPT4H1 0.10 0.04 lasso 6 0.04 3.7e-03 4.4 -5.2 1.9e-07 0.07 0.03 0.83 FALSE
4 GTEx Artery Tibial SUPT4H1 0.13 0.14 lasso 4 0.12 4.9e-10 5.2 -5.4 6.3e-08 0.02 0.02 0.98 FALSE
5 GTEx Brain Cerebellum SUPT4H1 0.26 0.10 enet 30 0.16 1.4e-05 5.6 -5.8 6.3e-09 0.06 0.06 0.83 FALSE
6 GTEx Colon Transverse SUPT4H1 0.24 0.17 lasso 4 0.14 5.8e-07 5.3 -5.3 1.1e-07 0.01 0.03 0.97 FALSE
7 GTEx Esophagus Mucosa SUPT4H1 0.07 0.04 lasso 3 0.04 6.1e-04 5.6 -5.5 3.7e-08 0.01 0.02 0.97 FALSE
8 GTEx Esophagus Muscularis SUPT4H1 0.14 0.15 lasso 2 0.13 2.3e-08 5.3 -5.3 1.1e-07 0.01 0.03 0.97 FALSE
9 GTEx Heart Atrial Appendage RAD51C 0.14 0.06 lasso 6 0.07 4.5e-04 5.2 -5.3 1.1e-07 -0.01 0.06 0.69 FALSE
10 GTEx Muscle Skeletal SUPT4H1 0.14 0.12 enet 24 0.12 1.2e-11 5.2 -5.9 3.5e-09 0.01 0.02 0.98 FALSE
11 GTEx Nerve Tibial SUPT4H1 0.21 0.10 lasso 4 0.07 6.8e-06 5.2 -5.2 2.6e-07 0.00 0.03 0.96 FALSE
12 GTEx Testis SUPT4H1 0.17 0.10 lasso 7 0.07 6.4e-04 5.2 -6.0 2.2e-09 -0.02 0.03 0.93 TRUE
13 GTEx Thyroid SUPT4H1 0.07 0.05 lasso 2 0.08 1.5e-06 5.1 -6.0 2.4e-09 0.01 0.04 0.93 FALSE
14 GTEx Vagina HEATR6 0.28 0.02 lasso 10 0.01 1.8e-01 -7.6 -6.3 2.2e-10 0.91 0.02 0.71 FALSE
15 NTR Blood MIR21 0.01 0.02 lasso 2 0.02 9.0e-06 -4.2 -5.5 3.3e-08 0.81 0.14 0.86 FALSE
16 The Cancer Genome Atlas Soft Tissue Sarcoma CLTC 0.07 0.03 lasso 3 0.02 1.5e-02 -7.0 -7.1 1.6e-12 0.88 0.00 0.94 FALSE
17 The Cancer Genome Atlas Thyroid Carcinoma BZRAP1 0.05 0.04 blup 59 0.03 2.7e-04 -3.2 5.9 2.8e-09 0.00 0.02 0.67 FALSE
18 The Cancer Genome Atlas Thyroid Carcinoma SUPT4H1 0.05 0.04 lasso 3 0.03 9.5e-04 5.2 -5.3 1.3e-07 -0.02 0.01 0.98 FALSE