TWAS hub - SUPT4H1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0680	0.0360	6.9e-03	0.083	NA	0.057	NA	0.069	2.8e-07	NA	2.0e-05	NA	2.5e-06
2	GTEx	Adipose Visceral Omentum	0.1000	0.0450	2.9e-03	0.043	NA	0.029	NA	0.040	2.7e-03	NA	1.2e-02	NA	3.7e-03
3	GTEx	Artery Tibial	0.1270	0.0473	1.5e-05	0.137	NA	0.108	NA	0.125	7.1e-11	NA	8.3e-09	NA	4.9e-10
4	GTEx	Brain Cerebellum	0.2620	0.0880	1.3e-04	0.104	NA	0.164	NA	0.151	5.7e-04	NA	1.4e-05	NA	3.2e-05
5	GTEx	Brain Putamen basal ganglia	0.2950	0.0940	1.2e-04	0.303	NA	0.254	NA	0.261	6.0e-08	NA	9.4e-07	NA	6.5e-07
6	GTEx	Colon Transverse	0.2370	0.0660	1.4e-07	0.171	NA	0.116	NA	0.135	1.5e-08	NA	3.6e-06	NA	5.8e-07
7	GTEx	Esophagus Mucosa	0.0670	0.0300	2.1e-03	0.042	NA	0.035	NA	0.044	8.8e-04	NA	2.0e-03	NA	6.1e-04
8	GTEx	Esophagus Muscularis	0.1360	0.0480	4.6e-05	0.148	NA	0.118	NA	0.131	2.9e-09	NA	1.3e-07	NA	2.3e-08
9	GTEx	Heart Atrial Appendage	0.1690	0.0780	6.9e-03	0.006	NA	0.010	NA	0.022	1.7e-01	NA	1.1e-01	NA	3.6e-02
10	GTEx	Muscle Skeletal	0.1446	0.0420	4.6e-08	0.119	NA	0.118	NA	0.116	1.0e-11	NA	1.1e-11	NA	2.0e-11
11	GTEx	Nerve Tibial	0.2059	0.0561	6.7e-07	0.102	NA	0.073	NA	0.073	1.1e-07	NA	6.8e-06	NA	6.8e-06
12	GTEx	Pituitary	0.3410	0.1490	5.9e-03	0.089	NA	0.038	NA	0.050	3.1e-03	NA	4.1e-02	NA	2.2e-02
13	GTEx	Skin Sun Exposed Lower leg	0.1310	0.0370	1.9e-08	0.146	NA	0.145	NA	0.144	4.4e-12	NA	4.8e-12	NA	6.2e-12
14	GTEx	Testis	0.1720	0.0600	2.1e-04	0.098	NA	0.049	NA	0.067	3.9e-05	NA	3.1e-03	NA	6.4e-04
15	GTEx	Thyroid	0.0730	0.0340	3.1e-03	0.049	NA	0.074	NA	0.078	1.3e-04	NA	2.6e-06	NA	1.5e-06
16	NTR	Blood	0.0775	0.0207	9.2e-13	0.048	0.051	0.070	0.060	0.069	2.4e-15	5.8e-16	1.4e-21	1.5e-18	2.7e-21
17	YFS	Blood	0.3316	0.0378	0.0e+00	0.197	0.220	0.234	0.237	0.211	3.7e-62	2.5e-70	2.4e-75	2.9e-76	4.5e-67
18	TCGA	Thyroid Carcinoma	0.0490	0.0240	4.2e-04	0.041	0.021	0.014	NA	0.028	7.3e-05	3.6e-03	1.3e-02	NA	9.5e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Loneliness, isolation	7.6	10.4	13.5	-3.3	-3.2	-3.4	-2.3	-1.6	-3.7	-3.4	-3.3	-3.4	-3.7	-3.4	-3.1	-3.2	-3.1	-3.3	-3.6	-3.0	-3.3
Rheumatoid Arthritis	7.1	9.7	15.2	3.4	2.9	3.4	2.5	1.1	3.6	3.4	3.4	3.3	3.9	3.4	2.5	2.7	3.2	3.7	2.9	2.6	3.3
Supplements: Calcium	7.0	7.7	10.3	-3.0	-2.3	-2.9	-2.4	-3.0	-2.8	-2.8	-3.0	-2.9	-2.7	-3.0	-2.1	-2.7	-3.2	-2.8	-2.5	-2.5	-3.0
Prostate Cancer	6.8	9.6	13.8	3.2	3.2	3.2	3.0	3.6	3.2	3.2	3.2	3.4	3.7	3.2	3.2	3.0	2.7	3.2	1.5	2.2	3.3
Supplements: Glucosamine	6.0	7.8	14.1	-2.8	-3.2	-2.7	-2.3	-3.8	-2.6	-2.6	-2.8	-2.8	-2.7	-3.0	-2.2	-3.1	-2.8	-3.3	-1.9	-2.2	-3.0
Seen doctor (GP) for nerves, anxiety, tension or depression	5.4	8.2	14.4	-2.8	-3.1	-2.9	-3.8	-2.2	-2.9	-3.0	-2.8	-3.1	-2.9	-3.0	-2.3	-2.5	-3.1	-3.1	-2.5	-2.2	-3.0
Pulse rate	4.8	8.0	15.9	3.2	1.7	3.2	1.2	2.1	3.1	3.2	3.2	2.6	2.1	3.2	2.9	4.0	2.8	2.1	3.6	2.0	3.2
Serious illness, injury or assault to yourself	4.7	5.7	8.5	-2.5	-2.2	-2.5	-1.7	-1.9	-2.4	-2.6	-2.5	-2.5	-2.5	-2.5	-2.5	-2.7	-2.5	-1.9	-2.9	-1.4	-2.7
Relative age of first facial hair	4.6	9.4	12.5	-3.3	-2.2	-3.4	-2.4	-3.1	-3.2	-3.4	-3.3	-2.8	-3.5	-3.2	-3.2	-3.2	-3.4	-3.1	-2.7	-2.2	-3.1
Vitamin and mineral supplements	4.4	6.0	9.1	2.5	1.9	2.4	3.0	2.2	2.4	2.4	2.5	2.7	2.9	2.7	1.9	2.4	2.6	1.9	1.9	2.4	2.7
Pulse rate, automated reading	4.3	14.0	22.8	4.3	1.4	4.1	2.1	1.7	4.5	4.1	4.3	3.9	2.8	4.2	3.7	4.8	4.0	3.0	4.2	3.6	4.3
Crohns Disease (2012)	4.2	6.8	9.8	-2.9	-1.7	-3.1	-2.4	-1.6	-3.0	-3.1	-2.9	-2.6	-2.1	-3.0	-2.1	-2.7	-2.3	-2.1	-2.7	-3.0	-2.7
Verbal and Numeric Reasoning (VNR)	4.1	9.9	26.0	-2.8	-3.1	-3.0	-3.7	-5.1	-2.2	-2.9	-2.8	-2.3	-3.2	-2.9	-2.6	-3.8	-3.5	-3.5	-2.3	-2.6	-3.0
Mineral and other dietary supplements	3.9	5.3	12.6	2.0	3.1	2.1	2.6	3.5	1.8	2.2	2.0	2.3	2.3	2.3	1.6	1.8	2.8	2.0	1.4	2.0	2.4
Diabetes diagnosed by doctor	3.8	6.3	10.1	2.6	2.2	2.7	3.2	1.8	2.6	2.7	2.6	2.7	2.9	2.6	2.6	1.9	2.4	2.1	1.4	2.8	2.6
Blood Eosinophil Count	3.7	28.3	35.8	-5.3	-5.2	-5.4	-5.8	-4.3	-5.3	-5.5	-5.3	-5.1	-5.9	-5.2	-5.0	-5.1	-6.0	-6.0	-5.0	-4.9	-5.3
Type 2 Diabetes (T2D) (2018)	3.5	6.5	14.7	2.6	2.2	2.7	3.8	2.3	2.5	2.7	2.6	2.6	2.9	2.6	2.3	1.8	2.4	2.8	0.5	2.8	2.4
Ever had bowel cancer screening	3.4	4.0	10.0	-1.9	-2.3	-1.8	-2.5	-3.2	-1.7	-1.8	-1.9	-1.9	-1.9	-2.0	-2.0	-1.9	-2.4	-1.0	-1.4	-1.7	-2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.3	3.9	8.2	2.0	1.5	2.1	2.9	2.5	1.9	2.1	2.0	1.7	2.1	2.0	1.9	1.4	2.1	1.6	1.1	2.1	1.8
HbA1C	3.2	3.5	7.0	-1.9	-2.2	-2.0	-0.8	-1.7	-2.0	-2.3	-1.9	-1.9	-1.1	-1.7	-2.6	-2.0	-2.3	-1.5	-2.1	-0.5	-1.8
Qualifications: College or University degree	3.2	10.0	12.4	-3.5	-2.3	-3.3	-3.1	-3.5	-3.4	-3.3	-3.5	-2.1	-3.5	-3.1	-3.4	-3.4	-3.3	-3.3	-2.9	-3.0	-2.8
Medication: Metformin	3.1	4.4	6.0	2.3	2.3	2.4	2.3	1.6	2.3	2.4	2.3	2.5	2.4	2.3	1.4	1.5	2.1	1.6	1.5	1.8	2.2
Diastolic blood pressure, automated reading	3.1	9.6	17.3	3.2	4.2	3.2	3.3	2.9	3.6	3.1	3.2	3.9	3.2	3.3	2.0	2.0	2.8	3.3	1.7	2.1	3.3
Noisy workplace	3.0	3.7	6.9	2.1	1.6	2.0	1.7	2.6	1.8	1.9	2.1	1.9	2.3	2.0	1.3	1.4	1.8	2.6	0.8	1.3	2.1
Suffer from ‘nerves’	3.0	4.8	7.3	-2.1	-2.4	-2.2	-2.7	-2.0	-2.0	-2.2	-2.1	-2.7	-2.2	-2.4	-1.9	-1.4	-2.7	-1.7	-1.4	-2.3	-2.4
Multivitamins +/- minerals	2.9	3.7	6.1	-1.9	-1.6	-1.8	-2.2	-1.5	-2.0	-1.8	-1.9	-2.2	-2.5	-2.1	-1.4	-1.8	-2.2	-1.9	-1.6	-2.0	-2.1
Intelligence (Savage-Jansen 2018)	2.8	8.5	32.5	-2.4	-3.5	-2.5	-3.0	-5.7	-1.7	-2.4	-2.4	-1.5	-2.3	-2.4	-2.8	-3.6	-3.4	-3.6	-2.3	-1.6	-2.4
Fluid intelligence score	2.8	5.8	14.8	-2.1	-2.7	-2.3	-2.5	-3.8	-1.6	-2.3	-2.1	-1.6	-2.2	-2.2	-2.4	-3.0	-2.9	-2.4	-2.3	-1.5	-2.3
Supplements: Fish oil (including cod liver oil)	2.8	3.6	5.8	-1.8	-2.4	-1.9	-2.3	-2.2	-1.5	-2.0	-1.8	-2.1	-1.8	-1.9	-2.1	-1.4	-2.4	-1.4	-1.2	-1.5	-2.0
Unable to work because of sickness or disability	2.8	3.6	6.8	-1.9	-1.7	-2.1	-0.5	-1.8	-1.8	-2.1	-1.9	-1.9	-1.7	-2.0	-2.3	-2.0	-2.1	-1.6	-2.6	-1.2	-2.1
Type 2 Diabetes (T2D) (2012)	2.7	3.1	11.3	-1.8	-0.8	-1.9	0.5	-0.6	-1.8	-1.7	-1.8	-1.6	-1.0	-2.0	-0.7	-2.8	-1.8	-1.4	-3.4	-1.0	-2.1
Lung FEV1/FVC ratio	2.7	13.5	20.8	-3.9	-4.1	-4.0	-3.8	-3.7	-3.8	-3.9	-3.9	-4.6	-4.3	-4.0	-3.3	-2.9	-3.2	-2.9	-2.2	-2.9	-4.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.7	3.2	4.9	-1.8	-1.5	-1.9	-2.0	-2.0	-1.7	-1.9	-1.8	-1.3	-1.5	-1.9	-2.1	-2.2	-1.7	-1.8	-1.6	-1.5	-1.7
High cholesterol (Self-reported)	2.6	4.6	8.1	2.4	2.3	2.4	2.4	1.0	2.4	2.5	2.4	2.1	2.4	2.2	2.1	1.4	1.2	2.8	1.5	2.3	2.0
Alzheimer’s Disease (including proxy)	2.5	3.7	9.9	2.0	2.5	2.0	0.8	0.6	2.2	1.9	2.0	1.5	1.1	2.0	1.4	2.6	1.3	1.4	3.2	2.3	1.8
Birth weight of first child	2.5	4.5	11.4	-2.3	-1.8	-2.2	-1.7	-1.8	-2.2	-2.2	-2.3	-2.0	-1.4	-2.1	-3.4	-2.1	-2.4	-1.9	-1.6	-1.4	-2.2
Nervous feelings	2.4	4.4	5.8	-2.2	-1.9	-2.2	-2.3	-1.9	-2.1	-2.1	-2.2	-2.4	-2.3	-2.3	-2.3	-1.7	-2.2	-2.0	-1.2	-2.0	-2.3
Tinnitus: Yes, but not now, but have in the past	2.3	2.4	4.6	-2.0	-0.7	-1.8	-1.2	-0.7	-2.1	-1.7	-2.0	-1.3	-1.8	-1.8	-1.2	-1.7	-1.5	-1.9	-1.2	-1.0	-1.5
Qualifications: CSEs or equivalent	2.3	3.0	7.9	1.6	2.8	1.6	1.6	2.6	1.4	1.5	1.6	1.0	1.9	1.6	1.6	2.0	1.8	2.0	1.1	0.5	1.4
Leg fat percentage (right)	2.3	8.2	12.7	3.4	1.2	3.2	3.2	1.1	3.3	3.3	3.4	2.6	2.8	3.2	2.8	2.4	2.7	3.6	2.1	2.9	2.9
Financial situation satisfaction	2.3	2.9	4.3	1.9	1.2	1.8	-0.9	2.0	1.9	1.7	1.9	1.7	1.0	1.9	0.9	2.0	2.1	1.7	2.0	0.8	2.0
Leg fat percentage (left)	2.3	8.2	12.3	3.5	1.2	3.3	3.1	1.1	3.3	3.4	3.5	2.6	2.7	3.2	2.8	2.5	2.6	3.5	2.1	2.8	2.9
Systolic blood pressure, automated reading	2.2	6.5	11.1	2.5	3.3	2.5	2.8	3.3	2.8	2.4	2.5	2.9	3.1	2.6	2.0	1.9	2.0	2.3	1.4	1.9	2.6
Diabetes (father)	2.2	2.7	5.4	1.7	0.4	1.7	2.3	1.4	1.6	1.8	1.7	1.5	1.3	1.7	2.1	1.6	1.6	0.3	1.7	1.9	1.8
Medication: Simvastatin	2.2	3.2	5.4	2.0	1.1	2.0	1.8	0.2	2.0	2.1	2.0	1.6	2.3	1.8	2.2	1.4	1.5	2.2	1.5	1.8	1.6
Prospective memory result	2.2	2.7	9.8	1.3	3.1	1.5	0.2	2.7	1.4	1.4	1.3	1.0	2.0	1.3	1.4	1.9	1.6	1.9	1.4	0.1	1.4
Age at first live birth	2.2	3.9	9.5	-2.0	-1.3	-2.0	-3.1	-3.0	-1.4	-1.9	-2.0	-1.4	-2.5	-1.9	-2.2	-1.4	-2.1	-1.0	-0.4	-2.4	-1.8
Supplements: Vitamin C	2.2	2.6	4.0	-1.8	-1.4	-1.8	-1.5	-1.8	-1.5	-1.8	-1.8	-1.6	-1.6	-1.7	-2.0	-1.2	-1.8	-1.2	-1.6	-1.2	-1.7
Age started oral contraceptive pill	2.2	2.8	6.4	-1.6	-2.5	-1.6	-0.9	-2.5	-1.4	-1.6	-1.6	-1.2	-1.8	-1.5	-1.9	-1.7	-1.5	-1.9	-1.6	0.1	-1.5
Vascular/heart problems diagnosed by doctor	2.2	6.0	9.2	-2.8	-2.3	-2.8	-2.8	-1.3	-2.9	-2.8	-2.8	-3.0	-2.9	-2.8	-2.2	-1.6	-2.2	-2.3	-1.0	-2.0	-2.6
Townsend deprivation index at recruitment	2.1	3.0	6.1	-1.7	-1.6	-1.7	-2.1	-0.6	-1.7	-1.7	-1.7	-1.5	-2.2	-1.6	-1.9	-1.7	-1.6	-2.5	-1.8	-1.1	-1.7
Qualifications: A levels/AS levels or equivalent	2.1	4.6	9.6	-2.1	-1.9	-2.1	-2.8	-3.1	-2.1	-2.1	-2.1	-1.6	-2.3	-2.0	-2.1	-2.0	-2.2	-1.8	-1.9	-2.2	-2.0
Family relationship satisfaction	2.1	2.6	5.9	-1.3	-2.4	-1.5	-2.1	-2.0	-1.5	-1.4	-1.3	-1.8	-2.0	-1.5	-1.0	-1.0	-1.5	-1.5	-1.0	-1.6	-1.5
Deep venous thrombosis (DVT) (self-reported)	2.1	2.7	4.4	1.6	0.8	1.6	1.7	0.3	1.6	1.6	1.6	2.1	1.7	1.7	1.8	1.5	1.8	1.8	1.4	1.9	2.0
HDL Cholesterol	2.0	3.3	7.1	1.6	2.7	1.9	1.2	1.5	1.6	1.8	1.6	1.8	2.1	1.7	1.9	1.1	2.0	2.6	1.8	1.6	1.7
Pain all over the body in last month	2.0	2.1	3.1	1.5	1.4	1.4	1.2	1.0	1.5	1.4	1.5	1.6	0.8	1.6	1.6	1.8	1.7	0.9	1.7	1.5	1.7
Illnesses of father: None of the above (group 1)	2.0	2.4	6.5	-1.6	-1.1	-1.8	-1.3	-1.0	-1.8	-1.9	-1.6	-1.4	-1.0	-1.5	-2.6	-1.7	-1.2	-0.4	-2.2	-1.2	-1.5
Blood Platelet Count	1.9	21.7	57.9	-4.5	-7.6	-4.8	-3.1	-3.2	-4.9	-5.0	-4.5	-4.5	-4.7	-4.5	-3.8	-4.5	-4.9	-5.7	-4.6	-2.1	-4.5
Other serious medical condition/disability diagnosed by doctor	1.9	2.5	5.9	-1.4	-2.4	-1.6	-1.8	-2.1	-1.2	-1.7	-1.4	-1.1	-2.0	-1.3	-1.6	-1.2	-1.3	-1.8	-1.2	-1.0	-1.2
Body mass index (BMI)	1.9	8.3	11.6	3.4	1.9	3.3	3.0	2.3	3.3	3.3	3.4	3.0	2.7	3.2	2.7	2.2	2.8	3.1	1.4	2.8	3.0
Neuroticism score	1.9	4.0	6.9	-1.9	-2.5	-1.9	-2.4	-2.3	-2.1	-1.9	-1.9	-2.2	-2.6	-2.0	-1.8	-1.6	-2.1	-0.9	-1.6	-1.6	-2.0
Commuting to job workplace: Car/motor vehicle	1.9	2.2	4.2	1.6	1.5	1.6	0.1	0.6	1.6	1.7	1.6	1.4	1.2	1.6	1.5	1.7	1.5	2.1	1.8	0.5	1.5
Ever depressed for a whole week	1.9	2.4	4.7	-1.4	-1.1	-1.5	-1.6	-1.9	-1.3	-1.5	-1.4	-1.3	-1.8	-1.5	-1.0	-2.2	-2.1	-1.1	-1.7	-1.2	-1.6
Hypothyroidism (self reported)	1.8	4.1	7.2	2.0	2.7	2.1	1.7	2.0	2.0	2.0	2.0	2.0	2.3	2.0	2.2	1.6	2.0	2.6	1.2	1.2	2.0
Financial difficulties in last 2 years	1.8	2.4	5.5	-1.5	-1.6	-1.6	-1.0	-0.8	-1.6	-1.6	-1.5	-1.2	-1.1	-1.6	-1.4	-2.1	-1.2	-2.0	-2.3	-1.3	-1.5
Diabetes (self-reported)	1.8	2.8	6.6	1.7	1.2	1.8	2.6	1.3	1.7	1.8	1.7	2.0	1.8	1.7	1.6	1.1	1.6	1.0	0.7	2.3	1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.8	2.4	6.1	-1.4	-1.9	-1.5	-1.8	-1.8	-1.6	-1.6	-1.4	-1.9	-2.5	-1.6	-0.7	-0.5	-1.9	-1.1	-0.9	-0.9	-1.5
Heart disease (mother)	1.8	2.2	4.2	1.7	0.8	1.5	1.1	0.4	1.9	1.5	1.7	1.6	1.7	1.5	1.2	1.1	1.6	1.8	0.9	2.1	1.4
Leg fat mass (left)	1.8	7.0	10.7	3.3	1.1	3.1	2.6	0.6	3.3	3.2	3.3	2.7	2.4	3.0	2.3	2.2	2.5	3.2	1.9	2.5	2.8
Breast Cancer	1.7	4.0	7.0	-2.1	-1.2	-2.2	-2.0	-2.6	-1.7	-2.3	-2.1	-1.2	-2.0	-2.0	-2.5	-2.1	-2.0	-1.3	-2.0	-2.2	-1.8
BMI	1.7	9.7	14.5	3.8	2.0	3.6	3.0	2.1	3.7	3.6	3.8	3.4	2.3	3.6	3.5	2.5	2.7	2.9	1.8	3.3	3.4
Eye problems/disorders: Diabetes related eye disease	1.7	1.9	3.7	1.4	0.8	1.4	1.9	1.2	1.3	1.4	1.4	1.3	1.6	1.3	1.6	0.8	1.6	1.2	0.3	1.9	1.3
Relative age voice broke	1.7	2.7	5.1	-1.6	-1.8	-1.7	-1.6	-2.3	-1.5	-1.6	-1.6	-1.5	-2.2	-1.6	-0.9	-1.5	-2.0	-2.0	-0.8	-0.9	-1.5
Leg fat mass (right)	1.7	6.5	9.9	3.2	1.0	3.0	2.6	0.6	3.1	3.0	3.2	2.5	2.3	2.9	2.1	2.0	2.4	3.2	1.8	2.6	2.6
Age at last live birth	1.7	2.5	5.0	-1.6	-0.9	-1.7	-2.2	-2.2	-1.4	-1.6	-1.6	-1.0	-1.6	-1.6	-1.7	-1.7	-1.6	-0.5	-0.9	-1.8	-1.5
Age at First Birth	1.6	2.3	11.5	-1.1	-2.7	-1.0	-1.2	-3.4	-0.8	-1.1	-1.1	-1.2	-1.5	-1.0	-2.0	-1.2	-1.0	-1.1	-0.5	-0.8	-1.2
Systolic Blood Pressure	1.6	8.2	14.9	2.8	3.6	2.9	3.8	3.1	3.0	2.8	2.8	3.5	3.9	3.0	2.5	1.6	2.0	2.8	0.9	2.1	2.9
Cardiovascular Disease	1.6	5.4	13.8	2.4	2.7	2.4	3.7	1.8	2.2	2.4	2.4	2.5	3.1	2.3	2.6	0.5	1.3	2.5	-0.5	1.9	2.1
Sensitivity / hurt feelings	1.6	2.8	6.9	-1.6	-2.0	-1.6	-2.3	-1.8	-1.8	-1.5	-1.6	-2.6	-2.1	-1.9	-0.7	-1.1	-1.6	-0.4	-0.3	-1.0	-2.0
Illness, injury, bereavement, stress in last 2 years	1.6	2.0	6.4	1.4	1.1	1.4	1.0	0.0	1.4	1.4	1.4	1.3	0.9	1.5	0.8	2.0	1.4	1.4	2.5	1.1	1.6
Bipolar Disorder (2018)	1.5	2.4	4.7	-1.7	-1.1	-1.9	-1.7	-0.9	-1.6	-2.0	-1.7	-1.3	-1.2	-1.6	-2.2	-1.5	-1.2	-1.0	-1.4	-1.6	-1.5
Irritable Bowel Disease (IBD)	1.5	3.5	6.2	-2.2	-1.4	-2.3	-1.9	-1.0	-2.1	-2.3	-2.2	-2.5	-1.1	-2.4	-1.5	-1.5	-1.7	-1.3	-1.1	-2.0	-2.3
Body Mass Index (BMI) (2010)	1.5	2.1	3.2	1.7	0.7	1.7	1.0	0.8	1.7	1.8	1.7	1.4	1.4	1.6	1.5	1.5	1.5	0.9	1.6	1.3	1.6
Waist circumference	1.5	5.4	9.1	2.9	1.1	2.7	2.6	0.5	3.0	2.8	2.9	2.5	2.2	2.7	1.4	1.5	2.1	2.4	1.5	2.8	2.3
Hearing difficulty/problems with background noise	1.5	2.4	5.7	-1.6	-1.9	-1.5	-1.7	-2.4	-1.7	-1.4	-1.6	-1.5	-2.1	-1.5	-0.9	-1.1	-1.3	-1.1	-1.0	-1.3	-1.4
Arm fat percentage (right)	1.5	5.7	8.5	2.9	0.9	2.8	2.4	0.6	2.9	2.9	2.9	2.2	2.2	2.8	1.8	2.3	2.2	2.5	2.2	2.5	2.4
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.7	4.6	-1.2	-0.9	-1.2	-1.5	-0.2	-1.1	-1.3	-1.2	-1.1	-1.5	-1.2	-0.3	-1.7	-1.4	-1.0	-2.1	-1.6	-1.4
Qualifications: O levels/GCSEs or equivalent	1.5	2.5	5.7	-1.4	-2.4	-1.4	-1.7	-2.1	-1.1	-1.5	-1.4	-1.1	-1.8	-1.2	-2.2	-1.1	-1.2	-1.9	-1.1	-1.4	-1.3
Blood clot in the leg (DVT)	1.5	1.9	3.3	1.4	0.4	1.4	1.4	0.0	1.4	1.4	1.4	1.8	1.6	1.5	1.4	1.2	1.6	1.2	1.0	1.7	1.7
Chronic bronchitis/emphysema (mother)	1.5	1.8	4.9	-1.4	-1.9	-1.4	-0.6	-0.3	-1.4	-1.4	-1.4	-1.6	-1.3	-1.4	-0.1	-0.6	-1.2	-1.6	-0.8	-2.2	-1.3
Body fat percentage	1.5	6.0	9.5	3.0	0.8	2.9	2.7	0.1	3.1	3.0	3.0	2.2	2.5	2.8	1.8	2.1	2.2	2.8	2.1	2.7	2.4
Alzheimer’s Disease (in mother)	1.4	1.6	4.0	1.2	1.5	1.3	1.4	-0.3	1.3	1.3	1.2	1.0	1.3	1.3	0.9	1.6	0.4	0.6	1.8	2.0	1.1
Crohns Disease (2017)	1.4	3.1	5.3	-2.2	-0.6	-2.3	-1.3	-0.6	-2.3	-2.2	-2.2	-1.9	-0.9	-2.3	-1.4	-1.7	-1.4	-1.0	-1.3	-2.1	-2.0
Medication: Atenolol	1.4	1.7	3.6	-1.3	-0.3	-1.4	-1.6	-1.3	-1.2	-1.4	-1.3	-0.9	-1.1	-1.2	-1.8	-1.4	-1.5	-0.6	-1.2	-1.9	-1.3
Impedance of arm (left)	1.4	6.5	14.0	-2.7	-2.8	-2.7	-2.3	-3.7	-2.3	-2.6	-2.7	-2.8	-2.0	-2.6	-2.9	-1.6	-2.8	-2.6	-0.4	-1.9	-2.8
Guilty feelings	1.4	2.2	4.7	-1.3	-1.8	-1.4	-1.4	-1.7	-1.4	-1.4	-1.3	-1.1	-2.2	-1.2	-1.8	-1.3	-1.7	-0.8	-1.6	-1.6	-1.2
Pain experienced in last month	1.4	2.3	4.8	1.4	2.2	1.4	0.9	0.6	1.4	1.5	1.4	1.8	1.6	1.4	1.4	1.4	2.1	1.1	2.1	0.6	1.6
Impedance of arm (right)	1.3	5.8	14.4	-2.5	-2.8	-2.5	-2.6	-3.8	-2.1	-2.4	-2.5	-2.6	-2.1	-2.4	-2.9	-1.0	-2.5	-2.3	0.2	-1.9	-2.5
Medication: Cholesterol lowering	1.3	2.0	3.6	1.7	1.0	1.7	0.8	0.1	1.8	1.8	1.7	1.2	1.7	1.5	1.4	1.6	1.2	0.8	1.9	1.2	1.3
Arm fat mass (right)	1.3	5.5	8.2	2.9	1.0	2.8	2.5	0.8	2.8	2.8	2.9	2.4	2.1	2.7	1.9	1.9	2.3	2.6	1.8	2.3	2.4
Whole body fat mass	1.3	5.4	8.9	2.9	1.0	2.8	2.5	0.2	3.0	2.9	2.9	2.3	2.3	2.6	1.6	1.8	2.2	2.6	1.9	2.3	2.3
Osteoporosis (self-reported)	1.3	1.6	2.8	-1.5	-1.0	-1.4	-1.7	-0.7	-1.5	-1.3	-1.5	-0.9	-1.6	-1.3	-0.5	-1.0	-1.4	-1.5	-0.9	-1.2	-1.0
Pain type(s) experienced in last month: Hip pain	1.3	1.6	3.7	-1.4	-1.1	-1.4	-0.4	-0.6	-1.3	-1.4	-1.4	-1.3	-0.5	-1.4	-1.2	-1.9	-1.4	-0.9	-1.9	0.1	-1.5
Alcohol drinker status: Previous	1.3	1.4	3.9	-1.2	-1.0	-1.2	-1.3	-1.4	-1.2	-1.1	-1.2	-1.1	-1.1	-1.2	-1.6	-0.8	-0.9	-2.0	-0.5	-1.0	-1.1
Supplements: Zinc	1.2	1.3	2.2	-1.2	-1.1	-1.2	-1.5	-1.1	-1.2	-1.3	-1.2	-1.0	-0.9	-1.1	-1.0	-0.8	-1.4	-1.0	-1.2	-1.3	-1.0
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	2.4	1.2	1.0	1.2	0.9	1.4	1.4	1.1	1.2	1.3	1.5	1.3	0.2	1.5	1.3	1.6	0.8	0.7	1.1
Medication: Levothyroxine sodium	1.2	2.0	3.4	1.6	1.4	1.6	1.0	0.2	1.7	1.7	1.6	1.6	1.5	1.6	1.3	1.0	1.1	1.8	1.0	1.1	1.5
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	3.2	-1.7	-1.1	-1.7	-1.1	-0.1	-1.8	-1.8	-1.7	-1.5	-1.6	-1.6	-1.1	-1.6	-1.1	-0.6	-1.4	-1.3	-1.5
Gout (self-reported)	1.2	1.6	3.3	1.4	1.3	1.4	1.2	1.0	1.5	1.4	1.4	1.1	1.3	1.4	0.5	1.8	0.9	1.1	1.6	0.8	1.3
Medication: Seretide 50 evohaler	1.2	1.4	2.4	-1.3	-0.5	-1.3	0.0	-1.4	-1.1	-1.3	-1.3	-0.6	-0.9	-1.2	-1.2	-1.6	-1.2	-1.5	-1.4	-1.4	-1.0
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	6.3	1.1	1.3	1.2	2.0	2.5	0.6	1.1	1.1	0.6	1.2	1.0	0.9	0.9	1.3	1.1	0.3	0.2	0.9
Hypertension (Self-reported)	1.2	3.3	5.5	2.0	2.1	2.0	2.2	1.1	2.1	2.1	2.0	2.3	2.2	2.0	1.6	0.8	1.4	1.8	0.1	1.4	1.9
Average weekly red wine intake	1.2	1.7	4.6	-1.3	-0.9	-1.3	-2.1	-1.6	-1.2	-1.4	-1.3	-0.5	-1.3	-1.2	-1.4	-1.6	-1.0	-1.7	-0.8	-1.3	-1.0
Qualifications: nursing, teaching	1.2	1.8	4.2	-1.3	-1.3	-1.2	-1.5	-2.0	-1.1	-1.2	-1.3	-1.2	-1.3	-1.2	-1.6	-1.4	-1.7	-1.4	-1.0	-1.0	-1.4
Medication: Atorvastatin	1.2	1.5	3.6	1.3	1.9	1.2	1.6	1.5	1.3	1.1	1.3	1.1	1.9	1.2	0.5	0.6	0.2	1.2	-0.3	1.2	0.9
Commuting to job workplace: Cycle	1.2	1.5	3.9	-1.4	-0.6	-1.3	-1.7	-2.0	-1.4	-1.2	-1.4	-0.2	-0.9	-1.0	-1.3	-1.1	-0.7	-2.0	-0.4	-1.0	-0.5
Myopia	1.2	1.8	3.6	1.2	1.0	1.4	1.8	-0.7	1.5	1.6	1.2	1.6	1.5	1.3	1.9	0.8	0.6	1.2	1.2	1.5	1.2
Cholesterol lowering medication	1.2	1.8	4.2	1.6	0.4	1.6	1.9	0.0	1.5	1.6	1.6	1.5	1.4	1.5	1.2	0.2	0.3	1.8	-0.1	2.0	1.2
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	3.5	1.3	1.1	1.2	0.8	1.9	1.2	1.2	1.3	1.1	1.2	1.2	1.3	1.1	1.1	0.9	0.5	0.6	1.2
Mouth/teeth dental problems	1.1	1.7	4.5	1.1	2.1	1.2	1.7	1.3	1.1	1.2	1.1	1.6	1.3	1.2	1.4	0.6	1.0	1.8	0.3	0.9	1.3
Number of live births	1.1	1.6	3.1	1.1	1.7	1.2	1.2	1.4	0.9	1.1	1.1	1.7	1.6	1.4	1.3	0.1	1.8	0.9	0.1	0.9	1.4
Glaucoma (self-reported)	1.1	1.3	3.1	1.3	0.4	1.3	0.2	0.7	1.2	1.2	1.3	1.1	0.2	1.3	1.1	1.3	1.8	-0.0	1.7	0.6	1.3
Wheeze or whistling in the chest in last year	1.1	2.0	4.5	1.5	1.5	1.5	1.2	1.7	1.6	1.4	1.5	2.1	1.4	1.7	1.3	0.8	1.4	1.1	0.3	1.1	1.8
Arm fat percentage (left)	1.1	4.4	6.7	2.6	0.7	2.5	2.4	0.4	2.6	2.6	2.6	1.9	1.9	2.4	1.6	1.9	1.8	2.2	1.7	2.3	2.0
Bipolar Disorder or Schizophrenia	1.0	2.4	6.6	-1.6	-0.8	-1.7	-0.8	0.4	-1.7	-1.8	-1.6	-1.6	-0.6	-1.6	-2.6	-1.7	-0.9	-1.5	-1.9	-1.5	-1.6
Ulcerative Colitis (UC)	1.0	1.9	3.5	-1.4	-1.4	-1.5	-1.7	-1.0	-1.3	-1.6	-1.4	-1.9	-1.0	-1.6	-1.0	-1.0	-1.3	-1.2	-0.8	-1.1	-1.7
Schizophrenia (2014)	1.0	2.2	5.4	-1.4	-1.0	-1.4	-0.6	0.6	-1.7	-1.5	-1.4	-1.9	-1.0	-1.5	-2.3	-1.4	-1.2	-1.9	-1.9	-1.3	-1.7
Ulcerative Colitis	1.0	1.5	4.0	-1.1	-1.5	-1.3	-0.9	-1.0	-1.1	-1.4	-1.1	-2.0	-0.8	-1.3	-1.5	-0.6	-1.2	-0.9	-0.5	-1.0	-1.6
Medication: Co-codamol	1.0	1.2	2.7	-1.1	-1.2	-1.1	-1.6	-1.0	-1.2	-1.1	-1.1	-1.2	-1.7	-1.1	-0.0	-0.6	-0.5	-0.4	-0.7	-1.4	-1.0
Trunk fat percentage	1.0	4.2	7.2	2.5	0.6	2.4	2.3	-0.4	2.7	2.5	2.5	1.7	2.2	2.2	1.4	1.7	1.8	2.3	1.9	2.2	1.8
Hand grip strength (right)	1.0	2.7	4.4	1.5	2.1	1.5	1.8	0.6	1.3	1.6	1.5	2.0	2.1	1.6	2.0	0.5	1.6	2.0	0.9	2.1	1.8
High blood pressure	1.0	2.9	5.5	1.9	1.9	1.9	2.3	0.7	2.0	1.9	1.9	2.2	2.1	1.8	1.6	0.7	1.4	1.6	0.1	1.2	1.7
Hair/balding pattern: Pattern 3	1.0	1.5	4.8	-1.4	-0.9	-1.4	0.3	-0.9	-1.5	-1.3	-1.4	-1.4	-0.7	-1.4	-2.2	-1.2	-0.8	-1.0	-0.8	-0.6	-1.5
Medication: Amlodipine	1.0	1.5	3.8	0.9	1.8	1.0	2.0	0.6	1.1	0.9	0.9	1.6	1.9	1.0	0.9	-0.6	1.2	0.2	-0.9	1.6	0.9
Pulse wave peak to peak time	1.0	1.1	3.4	-1.1	-0.3	-1.1	-0.3	-1.0	-1.0	-1.1	-1.1	-1.1	-0.8	-1.2	-1.0	-1.2	-1.2	-0.5	-1.9	-1.1	-1.2
Number of self-reported non-cancer illnesses	1.0	1.7	3.8	1.6	0.6	1.5	1.3	0.6	1.6	1.5	1.6	1.5	1.8	1.5	0.8	0.6	0.9	0.8	0.5	2.0	1.3
Commuting to job workplace: Public transport	1.0	1.2	3.1	-1.0	-1.0	-1.0	-0.1	-1.4	-0.8	-1.0	-1.0	-0.5	-1.3	-1.0	-1.1	-1.6	-0.8	-1.8	-1.4	-0.9	-0.9
Medication: Bendroflumethiazide	1.0	1.5	3.9	1.4	1.0	1.5	1.3	0.1	1.5	1.5	1.4	1.2	2.0	1.4	0.7	1.1	0.9	0.7	0.8	1.4	1.1
Worry (Nagel 2018)	0.9	2.0	7.0	-1.0	-2.0	-1.1	-2.6	-1.9	-1.1	-1.0	-1.0	-1.7	-1.6	-1.2	-1.3	-0.2	-1.7	-0.7	0.1	-1.1	-1.2
Neuroticism	0.9	2.2	5.8	-1.3	-1.6	-1.3	-2.4	-1.7	-1.5	-1.2	-1.3	-1.5	-2.3	-1.4	-1.2	-0.9	-1.4	-0.3	-0.6	-1.8	-1.3
Trunk fat mass	0.9	3.9	6.7	2.4	0.9	2.3	2.2	-0.3	2.6	2.4	2.4	1.9	2.1	2.2	1.2	1.5	1.8	2.3	1.6	2.0	1.9
Had menopause	0.9	1.2	2.4	1.2	-0.2	1.2	0.4	-0.3	1.4	1.2	1.2	1.1	1.6	1.1	1.1	0.9	1.2	0.3	1.5	1.2	1.0
Hair/balding pattern: Pattern 4	0.9	2.3	8.6	-1.4	-1.7	-1.4	-2.1	-2.9	-1.3	-1.4	-1.4	-1.0	-1.1	-1.3	-1.2	-1.6	-1.1	-1.8	-0.9	-0.1	-1.3
Worry too long after embarrassment	0.9	1.5	5.0	-1.0	-1.9	-1.0	-1.4	-2.2	-1.2	-0.9	-1.0	-1.3	-0.7	-1.2	-0.2	-1.2	-1.6	-0.9	-1.2	-0.7	-1.2
Medication: Aspirin	0.9	1.2	4.1	-0.7	-1.3	-0.8	-0.9	-2.0	-0.4	-0.8	-0.7	-0.2	-0.1	-0.7	-1.7	-1.3	-1.4	-1.6	-1.1	-1.0	-0.8
Arm fat mass (left)	0.9	3.9	6.0	2.4	0.8	2.3	2.3	0.6	2.4	2.4	2.4	1.9	1.8	2.2	1.5	1.5	1.9	2.2	1.3	2.0	2.0
Height	0.8	14.7	37.9	-3.8	-3.2	-4.0	-4.7	-6.2	-3.2	-3.8	-3.8	-2.9	-2.9	-3.9	-4.9	-4.0	-3.4	-3.5	-2.0	-3.7	-3.6
Ever had hysterectomy (womb removed)	0.8	0.8	2.6	1.0	0.8	1.0	-0.0	1.6	1.0	0.9	1.0	0.9	0.4	1.0	1.0	1.2	0.8	0.5	1.1	0.4	1.0
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	2.0	-1.0	-0.7	-1.0	-0.4	-0.6	-0.9	-1.0	-1.0	-1.0	-0.9	-1.1	-0.7	-1.3	-1.4	-0.9	-1.4	-0.6	-1.2
Worrier / anxious feelings	0.8	1.6	6.3	-0.7	-2.4	-0.8	-2.1	-2.5	-1.0	-0.6	-0.7	-1.4	-1.8	-0.9	-0.6	-0.6	-1.1	-0.7	0.1	-0.4	-1.0
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.2	2.9	1.2	0.4	1.1	1.0	0.8	1.2	1.2	1.2	1.2	-0.0	1.3	1.6	1.7	0.4	0.8	0.8	1.4	1.3
Mouth/teeth dental problems: Dentures	0.8	1.3	4.9	-1.0	-1.8	-1.0	-2.2	-1.3	-0.8	-1.0	-1.0	-1.3	-1.6	-1.0	-0.5	-0.4	-1.0	-1.3	0.3	-0.7	-1.0
Illnesses of mother	0.8	1.0	2.1	-1.0	-1.2	-0.8	-1.3	-1.4	-1.2	-0.8	-1.0	-1.2	-1.4	-0.9	-1.0	-0.3	-1.0	-0.7	-0.1	-1.2	-0.9
Exposure to tobacco smoke at home	0.8	0.9	1.7	1.0	0.6	1.0	0.9	0.7	1.1	1.0	1.0	1.3	0.7	1.2	1.2	0.4	1.1	0.9	-0.1	1.1	1.2
Tense / ‘highly strung’	0.8	1.3	4.4	-0.9	-1.1	-1.0	-1.2	-0.5	-1.3	-1.0	-0.9	-2.1	-1.2	-1.1	-0.8	-0.4	-1.6	-0.4	-0.9	-1.2	-1.4
Peak expiratory flow (PEF)	0.8	1.8	3.2	-1.8	0.4	-1.6	-1.2	-0.2	-1.8	-1.5	-1.8	-1.4	-0.9	-1.7	-0.5	-1.5	-1.1	-0.6	-1.0	-1.6	-1.5
Number of full brothers	0.8	1.0	6.3	0.9	1.2	0.9	0.7	2.5	0.8	0.7	0.9	1.0	0.7	0.9	1.0	0.7	0.5	1.0	-0.1	0.9	0.9
Medication: Gliclazide	0.8	0.9	2.5	0.9	0.8	0.9	0.3	0.6	0.9	0.8	0.9	1.6	0.3	1.1	1.1	0.6	1.5	0.2	0.9	0.7	1.3
Neuroticism (Nagel 2018)	0.7	1.6	5.4	-1.0	-1.7	-1.0	-2.3	-1.6	-1.3	-1.0	-1.0	-1.3	-1.7	-1.1	-0.6	-0.8	-1.4	0.0	-0.6	-1.3	-1.1
Mean Putamen Volume	0.7	0.8	2.4	0.5	1.5	0.6	0.6	-0.4	0.8	0.6	0.5	1.3	1.0	0.8	0.2	0.7	0.8	1.3	1.5	0.6	1.1
Triglycerides	0.7	1.2	6.3	-0.6	-1.6	-1.0	-0.4	-2.5	-0.5	-0.8	-0.6	-1.0	-0.8	-0.9	-1.8	-0.9	-0.6	-0.4	-1.0	-1.0	-0.9
Blood White Count	0.7	5.3	17.3	2.6	-2.1	2.4	1.7	1.7	2.1	2.4	2.6	1.7	1.2	2.5	2.6	2.7	1.2	1.3	2.1	4.2	2.4
Frequency of depressed mood in last 2 weeks	0.7	1.0	4.6	-0.6	-2.0	-0.8	0.2	-0.7	-0.6	-0.9	-0.6	-0.5	-0.9	-0.7	-1.1	-1.2	-1.4	0.0	-2.1	0.0	-0.7
Fed-up feelings	0.7	1.2	2.6	1.3	0.2	1.3	0.9	0.9	1.1	1.2	1.3	1.1	0.2	1.2	1.6	1.2	0.8	1.3	1.0	0.9	1.3
High blood pressure (mother)	0.7	1.0	2.8	-1.0	0.2	-1.0	-0.2	1.7	-1.0	-1.0	-1.0	-1.4	-0.5	-1.1	0.0	-1.4	-0.5	-0.4	-1.4	-0.8	-1.3
Qualifications: None of the above	0.7	1.4	3.7	1.0	1.4	1.0	1.3	1.5	0.8	0.9	1.0	0.5	1.6	0.8	1.5	0.7	1.2	1.9	0.4	1.8	0.8
Hip circumference	0.7	2.9	5.4	2.1	1.3	1.9	1.9	0.6	2.1	2.0	2.1	2.3	1.6	1.9	1.1	0.6	1.8	1.8	0.5	1.7	1.9
Lung cancer (father)	0.7	0.8	5.5	0.5	0.2	0.5	2.4	0.8	0.4	0.6	0.5	0.5	1.5	0.4	0.0	-0.4	-0.0	-0.1	-1.2	1.5	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	4.1	0.7	1.0	0.8	0.1	0.0	0.9	0.8	0.7	0.5	0.7	0.6	0.4	1.1	1.4	0.5	2.0	0.8	0.6
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	6.4	-0.6	-2.5	-0.7	-1.3	-1.3	-0.7	-0.7	-0.6	-1.1	-1.6	-0.6	-0.9	0.3	-0.4	-1.1	-0.0	-1.1	-0.7
Eye problems/disorders: Glaucoma	0.7	0.9	2.4	1.1	0.6	1.0	0.0	0.9	0.8	1.0	1.1	0.9	0.2	1.0	1.5	0.9	1.5	0.2	1.1	0.3	1.1
Medication: Blood pressure	0.7	1.3	4.0	1.4	0.8	1.3	0.8	0.2	1.4	1.3	1.4	1.6	1.4	1.3	0.7	-0.1	0.5	2.0	-0.6	0.8	1.1
Alcohol drinker status: Never	0.7	0.8	1.3	-0.8	-0.9	-0.7	-1.0	-0.7	-0.9	-0.6	-0.8	-1.1	-0.8	-1.0	-0.7	-0.9	-1.1	-0.9	-0.5	-1.0	-1.2
Impedance of whole body	0.7	3.5	10.6	-2.0	-2.2	-2.0	-1.5	-3.3	-1.7	-1.9	-2.0	-2.3	-1.3	-2.0	-1.8	-1.2	-1.9	-1.6	0.0	-1.3	-2.1
Reaction Time	0.6	1.1	4.4	-0.7	-0.1	-0.7	-2.1	1.8	-0.7	-0.8	-0.7	-1.0	-1.1	-0.6	-1.7	0.7	-0.3	-1.0	0.6	-1.4	-0.6
Ovarian Cancer	0.6	0.8	2.3	-0.8	-0.9	-0.8	-1.1	-0.9	-0.7	-0.8	-0.8	-0.2	-0.8	-0.6	-0.8	-0.8	-1.2	-1.5	-0.9	-1.0	-0.5
Coronary Artery Disease (CAD)	0.6	0.7	2.6	0.8	1.0	0.3	1.6	0.7	1.2	0.7	0.8	0.5	1.2	0.2	0.6	0.5	0.3	0.5	0.4	1.2	0.5
Blood Red Count	0.6	5.8	9.3	2.9	-0.3	2.9	2.7	0.7	2.8	3.0	2.9	1.9	2.4	2.8	2.9	1.9	1.7	2.0	1.7	3.0	2.3
Severe depression (siblings)	0.6	0.7	2.0	-0.9	-0.7	-0.8	0.0	-0.8	-0.9	-0.8	-0.9	-0.8	-1.0	-1.0	-0.2	-1.4	-0.6	-0.5	-1.1	-0.6	-1.0
Had other major operations	0.6	0.7	2.3	-0.8	0.2	-0.9	-0.3	-0.3	-0.4	-1.0	-0.8	-0.3	0.3	-0.8	-1.2	-1.5	-0.5	-1.0	-1.5	-0.5	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	3.8	1.0	1.4	1.1	1.9	0.9	0.9	1.1	1.0	1.1	1.9	1.2	0.0	1.0	1.1	0.9	1.0	1.4	1.1
Forced expiratory volume in 1-second (FEV1)	0.6	1.9	3.6	-1.7	-0.0	-1.7	-1.5	-1.1	-1.6	-1.6	-1.7	-1.5	-1.2	-1.7	-1.0	-1.0	-1.1	-0.4	-0.6	-1.9	-1.5
Standing height	0.6	6.3	17.9	-2.7	-1.4	-2.7	-2.1	-4.2	-2.2	-2.6	-2.7	-1.8	-2.0	-2.7	-3.0	-3.1	-2.0	-1.9	-1.6	-2.5	-2.4
Length of working week for main job	0.6	0.7	1.9	-0.9	0.1	-0.9	-0.5	-0.6	-0.7	-0.9	-0.9	-0.9	-0.3	-1.0	-0.2	-1.2	-0.9	-0.6	-1.4	-0.7	-0.9
Number of children fathered	0.6	0.7	1.8	-1.0	-0.5	-1.0	-1.3	-0.2	-0.9	-0.9	-1.0	-0.5	-0.3	-0.9	-0.9	-0.7	-0.8	-0.9	-0.3	-1.2	-0.7
Medication: Allopurinol	0.6	0.8	1.3	1.1	0.9	1.1	0.7	0.6	1.1	1.0	1.1	0.9	1.2	1.0	0.2	0.9	0.3	0.4	0.9	0.4	0.9
Chest pain or discomfort	0.6	0.9	2.8	-0.7	-1.3	-0.8	-0.2	-1.7	-0.7	-0.7	-0.7	-0.3	-0.5	-0.6	-1.2	-0.8	-1.5	-1.3	-1.4	0.3	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.9	-0.7	-1.4	-0.7	-0.5	-0.8	-0.8	-0.6	-0.7	-0.7	-1.1	-0.6	-0.8	-0.7	-1.0	-1.4	-0.8	0.2	-0.7
Illnesses of father: Heart disease	0.6	0.8	2.8	0.6	1.7	0.8	1.2	1.4	0.7	0.9	0.6	0.4	0.9	0.6	1.6	0.6	0.7	0.5	0.6	0.1	0.5
Irritability	0.6	1.1	3.9	-0.9	-0.3	-0.9	-2.0	-0.8	-1.0	-1.0	-0.9	-0.8	-1.4	-1.0	-0.9	-1.1	-0.9	-0.3	-1.1	-1.3	-0.9
Neuroticism (2016)	0.5	0.7	1.4	-0.9	-1.1	-0.8	-0.7	0.2	-0.9	-0.8	-0.9	-1.1	-1.0	-1.0	-1.2	-0.9	-0.6	-0.6	-0.9	-0.5	-1.0
Allergy or Eczema	0.5	1.4	3.7	-1.2	-1.0	-1.3	-1.5	-1.6	-1.0	-1.3	-1.2	-1.2	-1.9	-1.0	-1.7	-0.5	-0.9	-0.9	-0.3	-0.8	-1.2
Respiratory disease	0.5	1.1	4.2	-0.6	-0.6	-0.7	-1.6	-2.0	-0.2	-0.7	-0.6	-0.2	-0.6	-0.6	-1.4	-1.2	-1.5	-1.3	-0.8	-1.5	-0.6
Number of treatments/medications taken	0.5	0.9	1.9	1.2	-0.4	1.1	0.8	-1.3	1.3	1.2	1.2	1.0	1.1	1.1	0.3	0.3	0.4	0.7	0.6	1.4	0.8
Medication for hormone replacement therapy	0.5	0.5	2.2	0.5	0.1	0.5	0.3	-0.1	0.3	0.7	0.5	0.1	1.2	0.6	-0.0	1.3	0.9	0.6	1.5	0.7	0.4
Diabetes (mother)	0.5	0.6	2.7	0.1	1.6	0.1	1.3	1.0	0.2	0.1	0.1	-0.0	1.3	-0.1	0.3	-1.2	0.1	0.5	-1.2	0.4	-0.3
Taking other prescription medications	0.5	0.8	2.1	-0.8	-1.5	-0.9	-0.9	-1.4	-0.6	-0.9	-0.8	-0.7	-0.9	-0.9	-0.9	-0.9	-0.9	-1.0	-0.6	-0.6	-0.8
Age when periods started (menarche)	0.5	1.3	7.4	-0.7	-2.1	-0.9	-1.2	-2.7	-0.6	-0.9	-0.7	-0.6	-0.7	-0.7	-1.2	-1.0	-1.1	-1.2	-0.3	-0.4	-0.8
Chronic bronchitis/emphysema (father)	0.5	0.5	0.9	0.9	0.7	0.9	0.9	0.4	0.9	0.9	0.9	0.8	0.4	0.8	0.8	0.5	0.7	0.4	0.2	0.9	0.7
Alcohol usually taken with meals	0.5	0.8	2.4	-1.0	0.2	-0.9	0.2	0.8	-1.4	-0.9	-1.0	-0.4	-0.8	-0.9	-0.0	-1.2	-0.5	-1.3	-1.6	-0.6	-0.6
Weight	0.5	2.5	4.1	1.9	1.1	1.8	1.7	0.2	2.0	1.9	1.9	1.9	1.5	1.7	1.1	0.6	1.6	1.9	0.6	1.4	1.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	2.5	-1.6	0.0	-1.6	-1.1	-1.1	-1.4	-1.5	-1.6	-1.4	-1.1	-1.6	-0.9	-1.0	-0.9	-0.4	-0.7	-1.5	-1.4
Pulse wave reflection index	0.5	0.6	1.2	-0.9	-1.1	-0.8	-0.5	-0.1	-1.1	-0.9	-0.9	-0.8	-1.1	-0.8	0.0	-0.9	-0.2	-1.1	-0.0	-0.3	-0.7
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.0	0.5	0.5	0.5	0.9	0.4	0.6	0.6	0.5	1.0	0.6	0.7	0.6	1.2	1.2	-0.0	1.4	0.2	0.9
Osteoarthritis (self-reported)	0.5	0.6	1.1	-0.7	-0.6	-0.8	-1.0	-0.7	-0.6	-0.7	-0.7	-0.5	-0.5	-0.8	-0.8	-1.1	-0.9	-1.0	-0.5	-1.1	-0.7
Medication: Lisinopril	0.5	0.6	2.9	0.9	0.1	0.8	0.1	-0.7	0.9	0.9	0.9	1.0	0.3	1.0	-0.4	0.7	0.3	1.7	0.1	-0.1	0.8
Schizophrenia (2018)	0.4	0.8	2.4	-0.7	-0.1	-0.7	0.2	1.3	-1.0	-0.7	-0.7	-1.1	0.1	-0.8	-1.6	-0.9	-0.2	-1.2	-1.2	-0.5	-0.9
Schizophrenia vs Biploar Disorder	0.4	0.6	1.9	0.9	0.6	0.9	1.1	1.4	0.8	0.9	0.9	0.4	0.8	0.8	0.2	0.5	0.8	-0.3	0.3	0.8	0.6
LDL Cholesterol	0.4	0.6	1.7	-0.3	-0.6	-0.7	-1.1	-0.4	-0.2	-0.5	-0.3	-0.8	-1.0	-0.7	-1.3	-0.8	-0.7	0.1	-1.2	-0.8	-0.9
Chronotype (morning person)	0.4	0.9	4.3	0.4	1.2	0.6	-1.0	1.7	-0.0	0.5	0.4	-0.1	0.3	0.5	1.0	1.7	1.2	0.3	2.1	-0.0	0.6
Average weekly spirits intake	0.4	0.5	2.3	-0.6	-0.6	-0.6	-0.5	-1.5	-0.5	-0.5	-0.6	-0.3	-0.5	-0.7	-0.8	-1.1	-0.3	-0.6	-1.0	-0.8	-0.6
Angina	0.4	0.6	2.1	-0.5	-0.6	-0.5	-0.8	-1.4	-0.3	-0.3	-0.5	-0.9	-0.9	-0.6	-1.2	-0.4	-0.6	-0.7	0.1	-1.0	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.7	-0.5	-1.3	-0.5	0.6	-0.4	-0.6	-0.5	-0.5	-0.4	-0.9	-0.4	-1.2	-0.4	-1.0	-0.2	-1.2	-0.1	-0.3
Stomach or abdominal pain in last month	0.4	0.4	2.9	-0.1	-1.7	-0.1	-1.1	-0.6	-0.2	-0.1	-0.1	-0.4	-1.2	-0.2	-0.0	0.4	-0.5	-0.6	0.6	0.7	-0.1
Sitting height	0.4	2.9	9.2	-1.8	0.3	-1.9	-0.1	-2.5	-1.4	-1.8	-1.8	-0.9	-0.8	-2.0	-1.3	-3.0	-1.6	-1.0	-2.1	-1.7	-1.7
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	3.3	-0.3	-1.8	-0.4	-0.5	-0.4	-0.6	-0.4	-0.3	-0.8	-1.2	-0.5	0.6	-0.4	-1.5	-0.4	-1.5	0.1	-0.6
Hair/balding pattern: Pattern 2	0.4	0.5	2.2	-0.5	0.2	-0.5	-0.5	0.9	-0.5	-0.6	-0.5	-0.8	0.0	-0.7	0.5	-0.8	-0.8	-0.4	-1.5	-1.2	-0.7
Medication: Ramipril	0.4	0.5	2.2	-0.5	-0.7	-0.5	0.1	0.1	-0.3	-0.6	-0.5	-0.4	-0.0	-0.5	-0.6	-0.9	-0.7	-1.3	-1.5	0.2	-0.7
Illnesses of siblings	0.4	0.6	3.7	-0.7	0.5	-0.8	-1.9	-0.7	-0.6	-0.7	-0.7	-0.3	-0.6	-0.6	-0.9	-0.1	-0.2	-0.1	0.2	-1.3	-0.3
Asthma	0.4	0.8	2.1	-0.7	0.0	-0.7	-1.3	-1.1	-0.4	-0.7	-0.7	-0.2	-0.7	-0.6	-1.0	-1.3	-1.1	-1.5	-1.0	-1.1	-0.6
Depression (self-reported)	0.4	0.5	2.9	0.2	-0.7	0.2	-1.2	-1.3	0.3	0.3	0.2	-0.7	-0.3	-0.0	0.6	1.1	-0.5	-0.3	1.7	0.4	-0.2
Pulse wave Arterial Stiffness index	0.4	0.4	2.4	0.6	-0.0	0.6	-0.1	0.4	0.6	0.6	0.6	0.7	0.4	0.8	0.5	0.7	0.8	-0.0	1.5	0.7	0.8
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	3.6	0.9	0.8	0.9	1.0	0.0	1.0	0.9	0.9	0.9	1.1	0.9	1.1	0.3	0.6	1.9	0.2	0.5	0.8
Emphysema/chronic bronchitis	0.4	0.4	2.2	-0.2	-1.5	-0.3	0.4	-1.2	-0.2	-0.3	-0.2	-0.1	-0.4	-0.3	-0.0	-0.9	-0.5	0.3	-1.4	0.4	-0.3
Medication for pain relief, constipation, heartburn	0.4	0.7	3.8	0.5	0.9	0.5	0.4	2.0	0.3	0.5	0.5	0.7	0.2	0.6	1.0	1.1	1.5	0.5	0.2	-0.3	0.8
Had major operations	0.4	0.5	1.7	0.7	0.6	0.7	-0.3	0.9	0.6	0.7	0.7	0.1	0.7	0.6	0.5	1.1	1.0	0.4	1.3	0.1	0.5
Friendships satisfaction	0.4	0.4	1.2	0.7	-0.5	0.5	-1.0	-0.5	0.4	0.6	0.7	0.0	-0.9	0.5	0.8	0.6	1.0	-0.4	1.1	0.0	0.6
Medication: Aspirin	0.4	0.6	3.3	-0.2	-1.2	-0.3	-0.8	-1.8	0.0	-0.4	-0.2	0.2	0.2	-0.3	-0.8	-0.9	-1.0	-1.0	-0.8	-0.5	-0.3
Ever had prostate specific antigen (PSA) test	0.4	0.5	2.6	-0.1	-0.6	-0.2	-1.4	0.4	-0.2	-0.2	-0.1	-1.0	-0.3	-0.3	-1.1	0.3	0.0	-1.6	0.5	-0.1	-0.6
Fractured/broken bones in last 5 years	0.4	0.5	2.2	-0.6	-0.9	-0.6	-0.9	-0.9	-0.7	-0.6	-0.6	-0.1	-1.5	-0.5	-0.1	-1.0	-0.6	-0.6	-0.7	-0.7	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	3.3	-0.5	-0.7	-0.6	-0.6	-1.8	-0.4	-0.5	-0.5	-0.4	-0.3	-0.5	-0.8	-0.6	-0.9	-0.4	-0.2	0.2	-0.5
Alzheimer’s Disease (in father)	0.3	0.3	0.5	0.7	0.0	0.5	-0.7	-0.2	0.6	0.4	0.7	0.7	-0.5	0.6	0.2	0.7	0.5	0.5	0.7	0.4	0.7
Bipolar Disorder (2011)	0.3	0.3	3.1	-0.3	0.8	-0.2	0.7	1.8	-0.5	-0.3	-0.3	0.1	0.0	-0.0	-0.4	0.1	0.3	0.7	0.0	-0.4	-0.0
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.8	-0.6	-1.0	-0.7	-1.0	-0.8	-0.6	-0.8	-0.6	-1.0	-1.4	-0.6	-1.0	-0.1	-0.5	-0.7	-0.2	-0.3	-0.9
Impedance of leg (left)	0.3	1.6	5.3	-1.3	-1.6	-1.4	-0.8	-2.3	-1.2	-1.3	-1.3	-1.7	-1.1	-1.3	-1.0	-0.9	-1.1	-0.6	-0.1	-1.1	-1.4
Falls in the last year	0.3	0.4	1.7	-0.5	0.1	-0.6	0.1	-0.3	-0.1	-0.6	-0.5	0.2	-0.1	-0.5	-0.9	-0.8	-0.5	-0.8	-1.3	-0.9	-0.3
Birth weight	0.3	0.7	1.8	-0.7	-1.2	-0.7	-1.3	-0.2	-1.0	-0.8	-0.7	-1.2	-0.6	-0.8	-1.3	0.5	-0.2	-1.2	-0.0	-1.0	-0.8
Medication: Blood pressure	0.3	0.4	1.0	0.9	-0.1	0.8	0.7	-0.8	1.0	0.9	0.9	0.8	0.7	0.8	0.2	0.6	0.4	-0.1	0.3	0.4	0.6
Medication: Ibuprofen	0.3	0.3	1.2	0.4	0.8	0.5	0.6	0.4	0.4	0.6	0.4	0.3	0.3	0.5	0.4	0.4	0.3	0.4	1.1	1.0	0.4
Mean time to correctly identify matches	0.3	0.6	1.9	-0.5	0.2	-0.5	-1.4	1.4	-0.4	-0.5	-0.5	-0.7	-0.9	-0.4	-0.9	0.8	-0.3	-0.8	1.1	-1.0	-0.3
Alcohol intake frequency.	0.3	0.7	1.8	-0.6	-1.3	-0.6	-1.3	-0.5	-1.0	-0.5	-0.6	-1.2	-0.5	-0.7	-0.4	0.1	-0.5	-1.3	-0.2	-1.1	-0.8
Mood swings	0.3	0.5	1.5	0.9	-0.0	0.9	-0.1	0.2	0.6	0.9	0.9	1.0	-0.3	0.8	1.1	0.6	0.6	1.2	0.3	0.4	0.9
Long-standing illness, disability or infirmity	0.3	0.5	1.8	0.9	-0.4	0.7	0.9	-0.2	1.1	0.6	0.9	0.7	0.9	0.7	-0.2	0.2	0.3	-0.1	0.0	1.4	0.6
Commuting to job workplace: Walk	0.3	0.4	1.3	-0.5	-0.5	-0.6	0.7	0.3	-0.7	-0.6	-0.5	-0.6	-0.4	-0.5	-0.5	-0.5	-0.3	-1.1	-1.1	-0.2	-0.6
Medication for cholesterol	0.3	0.4	1.8	-0.4	0.7	-0.3	-0.5	0.8	-0.3	-0.3	-0.4	-0.5	-0.8	-0.3	0.1	1.1	0.2	-0.9	1.3	-0.9	-0.1
Back pain experienced in last month	0.3	0.4	2.1	-0.3	-1.3	-0.4	0.3	-0.2	-0.3	-0.4	-0.3	-0.8	0.2	-0.5	-0.3	-0.2	-0.2	-0.5	-1.4	0.9	-0.7
Asthma (self-reported)	0.3	0.6	2.0	-0.5	0.0	-0.6	-1.0	-1.2	-0.3	-0.5	-0.5	-0.1	-0.6	-0.5	-0.8	-1.2	-1.1	-1.4	-0.9	-1.0	-0.4
Ever smoked	0.3	0.5	3.2	-0.6	-0.8	-0.7	0.7	0.5	-0.7	-0.8	-0.6	-0.3	-0.5	-0.6	-0.2	-0.9	-0.3	0.1	-1.8	-0.1	-0.5
Average weekly beer plus cider intake	0.3	0.5	4.4	-0.2	0.7	-0.1	0.3	0.7	-0.0	-0.3	-0.2	-0.1	0.5	-0.3	0.2	-1.2	-0.9	-0.3	-2.1	-0.5	-0.4
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.6	-0.3	-1.3	-0.2	-0.7	-0.7	-0.2	-0.2	-0.3	-0.6	0.7	-0.3	-1.1	-0.0	-0.6	-0.7	0.4	-0.5	-0.5
Depression (Nagel 2018)	0.2	0.3	1.5	-0.1	-1.0	-0.2	0.7	-0.5	0.0	-0.2	-0.1	0.0	-0.4	-0.1	-1.2	-0.4	-0.7	0.9	-1.1	-0.2	-0.1
Fasting Glucose	0.2	0.3	1.0	0.0	-0.3	0.8	1.0	-0.1	0.0	-0.1	0.0	0.2	1.0	0.7	-0.1	-0.3	-0.0	0.8	-0.7	0.5	0.1
Primary Biliary Cirrhosis	0.2	0.3	1.7	-0.2	0.6	-0.1	-0.3	1.2	-0.3	-0.1	-0.2	-0.5	-0.2	-0.2	0.0	0.6	0.7	0.3	0.5	-1.3	-0.2
Smoking Status	0.2	0.5	3.5	0.2	0.6	0.1	1.9	1.2	0.2	-0.0	0.2	0.5	0.3	0.2	0.1	-0.2	-0.0	0.7	-1.1	0.7	0.3
Impedance of leg (right)	0.2	1.0	4.7	-0.9	-1.3	-1.1	-0.3	-2.2	-0.9	-1.0	-0.9	-1.3	-0.8	-0.9	-0.5	-0.6	-0.8	-0.2	0.3	-0.6	-1.0
Current tobacco smoking	0.2	0.3	1.2	-0.2	0.6	-0.2	0.8	0.7	-0.3	-0.2	-0.2	-0.0	-0.3	-0.2	-0.5	-0.9	-0.5	0.2	-1.1	-0.2	-0.2
Average weekly fortified wine intake	0.2	0.2	2.0	0.1	-0.4	0.0	1.4	0.2	0.2	0.1	0.1	-0.4	0.3	-0.1	-0.1	-0.0	0.3	0.9	0.2	0.8	-0.3
Maternal smoking around birth	0.2	0.3	0.9	0.7	0.3	0.6	0.3	0.7	1.0	0.6	0.7	0.5	-0.2	0.6	-0.1	0.3	-0.2	0.1	-0.1	0.4	0.5
Forced vital capacity (FVC)	0.2	0.8	1.7	-1.2	0.5	-1.2	-0.9	-0.5	-1.0	-1.1	-1.2	-0.6	-0.6	-1.1	-0.8	-0.8	-0.7	-0.2	-0.6	-1.3	-0.8
Heart attack	0.2	0.2	1.0	-0.0	-1.0	0.0	-0.4	-0.5	0.1	0.1	-0.0	-0.3	1.0	-0.0	-0.9	0.3	-0.3	-0.6	0.7	-0.2	-0.2
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	1.0	-0.3	-0.5	-0.2	-0.3	0.3	-0.2	-0.2	-0.3	-1.0	-0.6	-0.4	-0.6	0.1	-0.3	-0.5	0.1	-0.7	-0.7
Father’s age at death	0.2	0.3	1.4	-0.4	-1.2	-0.4	-0.4	-1.2	-0.7	-0.3	-0.4	-0.6	-0.7	-0.4	0.2	-0.3	-0.3	-0.5	0.2	0.5	-0.5
Breastfed as a baby	0.2	0.2	1.7	-0.0	-0.6	-0.0	1.3	-0.1	-0.0	-0.0	-0.0	0.2	0.5	-0.1	0.2	-0.1	0.8	-0.2	-0.6	0.7	0.0
Loud music exposure frequency	0.2	0.2	0.6	-0.1	-0.5	-0.0	-0.5	0.7	-0.2	-0.0	-0.1	-0.7	-0.8	-0.2	0.3	-0.3	0.2	0.6	-0.2	-0.4	-0.4
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	1.0	-0.2	-0.3	-0.3	0.3	0.2	-0.2	-0.3	-0.2	-0.3	-0.1	-0.3	-0.7	-0.6	-0.9	-0.6	-1.0	0.5	-0.4
Headache pain in last month	0.2	0.4	1.5	0.5	0.2	0.5	-0.5	0.6	0.3	0.6	0.5	-0.3	-0.4	0.5	0.8	1.2	-0.1	1.2	0.9	-0.3	0.4
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.8	-0.5	0.2	-0.5	-0.0	-0.8	-0.5	-0.4	-0.5	-0.6	-0.1	-0.7	-0.5	-0.9	-0.7	-0.4	-0.2	-0.3	-0.6
Forced vital capacity (FVC), Best measure	0.2	0.7	1.2	-1.1	0.5	-1.1	-0.7	-0.8	-0.9	-1.0	-1.1	-0.6	-0.5	-1.0	-0.5	-0.9	-0.7	-0.2	-0.6	-0.9	-0.8
Arm fat-free mass (right)	0.2	0.8	2.0	1.0	1.4	0.9	1.1	0.4	1.0	0.9	1.0	1.3	0.7	0.8	0.6	-0.6	1.0	1.0	-0.8	0.3	0.9
Exposure to tobacco smoke outside home	0.2	0.3	0.9	-0.2	-0.4	-0.2	-0.8	0.3	-0.4	-0.3	-0.2	-0.6	-0.4	-0.4	0.8	-0.1	-1.0	-0.2	-0.3	-0.8	-0.5
Comparative body size at age 10	0.2	0.5	2.8	0.5	1.3	0.6	0.6	1.7	0.3	0.6	0.5	0.4	0.8	0.5	0.3	0.5	1.1	0.1	0.5	0.7	0.5
Health satisfaction	0.2	0.3	0.7	0.7	0.0	0.6	0.1	0.3	0.7	0.6	0.7	0.8	0.1	0.7	0.7	0.3	0.3	0.1	-0.1	0.8	0.7
Eye problems/disorders: None of the above	0.2	0.2	0.7	-0.6	0.2	-0.4	0.7	-0.0	-0.5	-0.3	-0.6	-0.5	0.2	-0.4	-0.5	-0.8	-0.5	-0.4	-0.1	0.3	-0.6
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.5	0.5	0.5	0.4	0.5	0.4	0.5	0.4	0.5	0.4	0.6	0.5	-0.7	0.1	0.5	-0.1	0.2	0.5	0.4
Angina (self-reported)	0.2	0.3	1.3	-0.1	-0.4	-0.1	-0.4	-1.1	-0.0	-0.0	-0.1	-0.7	-0.6	-0.3	-1.0	-0.1	-0.3	-0.3	0.4	-0.7	-0.6
Arm predicted mass (right)	0.2	0.8	2.2	1.0	1.5	0.9	1.1	0.5	0.9	0.9	1.0	1.3	0.6	0.8	0.7	-0.5	1.0	1.1	-0.8	0.3	0.9
Overall health rating	0.2	0.3	0.6	0.8	-0.1	0.7	0.4	0.4	0.8	0.7	0.8	0.7	-0.3	0.7	0.8	0.3	-0.1	0.3	-0.5	0.7	0.6
Illnesses of siblings: Diabetes	0.2	0.2	1.9	0.1	-0.2	0.2	1.4	0.2	0.0	0.3	0.1	-0.3	0.2	-0.0	0.4	-0.2	-0.8	-0.4	-0.1	0.8	-0.2
Smoking status: Previous	0.2	0.4	1.7	0.3	0.1	0.3	1.3	0.7	0.3	0.2	0.3	0.3	0.8	0.4	0.5	1.0	0.6	0.9	0.3	0.6	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	1.7	0.4	1.3	0.4	1.0	-0.1	0.5	0.4	0.4	0.6	0.7	0.4	0.0	-0.3	0.2	0.8	0.1	0.8	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	0.8	0.7	-0.2	0.5	-0.5	0.0	0.6	0.5	0.7	0.5	-0.4	0.6	-0.3	0.6	0.9	-0.1	0.2	0.5	0.6
Breast cancer (self-reported)	0.2	0.3	0.6	0.5	0.7	0.4	-0.7	0.6	0.4	0.3	0.5	0.7	0.3	0.4	0.2	0.4	0.5	0.7	0.5	0.1	0.6
Smoking status: Current	0.2	0.3	1.2	-0.3	0.4	-0.3	0.5	0.3	-0.3	-0.4	-0.3	-0.0	-0.6	-0.3	-0.9	-0.9	-0.6	0.2	-1.1	-0.4	-0.2
Hearing aid user	0.2	0.3	1.0	0.7	-0.5	0.4	-0.2	-0.4	0.4	0.3	0.7	0.6	-1.0	0.8	-0.2	0.7	0.4	0.2	0.2	0.1	0.8
Mother’s age at death	0.2	0.2	0.8	0.4	0.1	0.4	-0.4	-0.9	0.6	0.6	0.4	0.3	0.2	0.3	-0.2	0.7	-0.1	0.6	0.8	-0.0	0.3
Tinnitus: Yes, now most or all of the time	0.2	0.3	1.8	0.5	-0.6	0.6	0.5	0.1	0.3	0.5	0.5	-0.0	0.0	0.3	1.3	-0.1	-0.2	0.6	-0.5	0.5	0.2
Arm fat-free mass (left)	0.2	1.1	2.5	1.2	1.3	1.2	1.0	0.7	1.2	1.2	1.2	1.6	0.8	1.1	0.9	-0.0	1.3	1.2	-0.3	0.4	1.3
Risk taking	0.2	0.3	1.9	0.5	1.4	0.5	-0.2	0.8	0.5	0.5	0.5	0.5	0.9	0.5	-0.1	0.5	0.2	0.0	0.0	0.1	0.5
Basal cell carcinoma (self-reported)	0.2	0.2	0.9	0.4	0.6	0.5	0.8	0.9	0.3	0.4	0.4	0.1	0.9	0.4	0.3	-0.2	0.2	0.4	-0.3	0.4	0.2
Heart disease (siblings)	0.2	0.2	2.4	0.0	-1.6	-0.0	0.5	-0.4	-0.0	-0.0	0.0	-0.3	-0.1	0.0	0.1	0.1	0.1	-0.2	-0.1	0.9	-0.1
Arm predicted mass (left)	0.2	1.1	2.7	1.2	1.5	1.1	0.9	0.5	1.1	1.1	1.2	1.6	0.7	1.1	0.8	-0.1	1.4	1.2	-0.3	0.4	1.3
Depressed Affect (Nagel 2018)	0.1	0.2	1.8	0.3	-0.2	0.3	-0.5	0.2	0.1	0.3	0.3	0.3	-0.7	0.3	0.7	0.4	0.3	1.4	0.1	-0.5	0.5
Major Depression (MDD)	0.1	0.2	0.8	0.2	-0.1	0.2	-0.0	-0.2	0.2	0.3	0.2	-0.4	0.5	0.1	0.5	0.9	0.0	0.7	0.8	-0.1	-0.0
Lupus	0.1	0.2	0.8	0.3	-0.9	0.1	-0.2	-0.8	0.4	0.1	0.3	0.3	0.3	0.4	-0.1	0.7	-0.1	-0.3	0.9	-0.2	0.4
Heel T-Score	0.1	0.4	2.7	0.1	1.6	0.2	1.1	-0.3	0.4	0.3	0.1	0.5	1.1	0.3	-0.5	-0.8	-0.5	0.1	-0.1	0.7	0.2
Waist Hip Ratio (WHR)	0.1	0.6	2.6	0.6	-0.6	0.6	1.1	-1.4	0.9	0.7	0.6	-0.1	0.2	0.7	-0.4	0.8	-0.0	0.1	1.4	1.6	0.2
Lung FVC	0.1	0.4	2.7	0.1	1.6	0.1	-0.8	1.6	-0.1	0.0	0.1	-0.2	0.1	0.1	0.2	1.1	0.3	0.6	0.4	-0.2	0.0
Hand grip strength (left)	0.1	0.2	1.0	0.0	0.3	0.1	0.2	-0.8	-0.2	0.2	0.0	0.4	0.6	0.1	1.0	-0.3	0.3	0.4	0.4	0.7	0.4
Hearing difficulty/problems: Yes	0.1	0.1	0.5	-0.1	-0.4	-0.1	-0.1	-0.1	-0.5	-0.1	-0.1	-0.4	-0.6	-0.1	0.7	0.3	0.1	0.3	-0.5	-0.2	-0.1
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.9	0.1	-0.7	0.0	-0.7	0.1	-0.2	-0.0	0.1	-0.3	0.2	0.2	-0.1	0.4	0.2	-0.2	0.2	1.0	-0.0
Pack years adult smoking proportion	0.1	0.2	1.0	0.1	-0.4	0.1	-1.0	0.5	0.0	0.1	0.1	-0.4	-0.1	-0.0	-0.6	-0.8	-0.4	0.0	-0.7	0.1	-0.3
Leg fat-free mass (left)	0.1	0.5	1.5	0.7	0.9	0.7	0.6	0.1	0.9	0.7	0.7	1.2	0.5	0.7	-0.1	-0.4	0.7	0.9	-0.5	0.3	0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	1.1	-0.1	0.5	0.0	1.0	0.3	-0.2	0.0	-0.1	-0.2	1.0	-0.0	-0.9	-0.2	-0.2	-0.3	-0.2	0.0	-0.1
Leg predicted mass (left)	0.1	0.5	1.5	0.7	0.9	0.7	0.6	0.1	0.8	0.7	0.7	1.2	0.5	0.7	-0.1	-0.3	0.7	0.8	-0.5	0.3	0.8
Number of incorrect matches in round	0.1	0.2	2.1	-0.0	-0.5	-0.1	-0.6	-1.5	-0.0	-0.1	-0.0	-0.0	-0.2	-0.2	-0.6	-0.2	0.3	-0.3	0.7	0.0	-0.1
Past tobacco smoking	0.1	0.2	1.1	0.3	0.7	0.4	-1.1	-0.2	0.2	0.5	0.3	0.1	0.2	0.3	-0.1	0.1	0.2	-0.2	0.8	-0.2	0.2
Time employed in main current job	0.1	0.1	0.8	-0.1	0.5	0.0	0.6	0.4	-0.1	0.1	-0.1	-0.4	0.9	-0.2	0.4	0.0	-0.3	0.7	-0.0	-0.1	-0.3
Alcohol intake versus 10 years previously	0.1	0.2	0.9	0.5	0.3	0.4	-0.9	0.1	0.6	0.4	0.5	0.2	-0.1	0.4	-0.2	0.4	0.2	0.3	0.5	-0.2	0.2
Happiness	0.1	0.1	0.7	0.0	0.1	-0.0	-0.9	-0.2	-0.0	0.0	0.0	-0.3	-0.2	-0.2	0.4	-0.3	-0.6	-0.2	-0.3	-0.4	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.9	-0.0	0.5	-0.0	0.7	-0.2	-0.1	0.0	-0.0	-0.4	0.1	-0.1	-0.1	-0.5	-0.2	-0.2	0.3	0.9	-0.3
Medication: Lansoprazole	0.1	0.1	0.5	-0.0	-0.7	-0.1	-0.1	-0.5	0.2	-0.1	-0.0	-0.1	0.0	0.1	-0.6	0.4	0.1	0.3	0.4	0.2	0.1
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.5	-0.1	0.3	-0.1	-0.3	0.4	-0.1	-0.1	-0.1	-0.3	-0.1	-0.1	-0.5	-0.1	-0.4	0.0	-0.6	-0.7	-0.2
Medication: Paracetamol	0.1	0.1	0.9	0.2	-0.2	0.2	-0.2	-1.0	0.2	0.2	0.2	0.0	-0.1	0.2	-0.1	-0.1	-0.3	0.9	0.5	0.4	0.0
High blood pressure (siblings)	0.1	0.2	1.3	0.1	-0.6	0.2	1.1	0.5	-0.2	0.2	0.1	-0.5	0.2	-0.0	0.6	-0.3	-0.2	-0.6	-0.4	0.5	-0.4
Neck or shoulder pain in last month	0.1	0.1	0.6	0.2	-0.5	0.2	0.0	0.7	0.1	0.1	0.2	-0.0	-0.3	0.3	0.2	0.8	0.3	0.5	-0.1	0.1	0.3
Migraine (self-reported)	0.1	0.1	0.8	0.1	0.5	0.2	0.5	0.9	0.2	0.2	0.1	-0.1	-0.5	0.0	0.7	0.1	0.2	0.5	0.1	0.0	-0.1
Medication: Omeprazole	0.1	0.1	0.6	-0.0	-0.2	-0.0	0.1	-0.8	-0.1	0.1	-0.0	-0.2	0.1	-0.0	0.2	0.1	-0.4	-0.0	0.4	0.3	-0.1
Comparative height size at age 10	0.1	0.3	1.2	0.4	0.3	0.4	0.7	-0.5	0.5	0.5	0.4	0.3	-0.3	0.4	-0.1	0.7	0.5	1.1	1.0	0.0	0.4
Number of full sisters	0.1	0.2	0.9	0.1	-0.1	0.2	0.9	0.2	0.4	0.1	0.1	0.6	0.2	0.2	0.5	-0.3	0.4	-0.0	-0.7	0.3	0.3
Leg pain on walking	0.1	0.1	0.6	-0.1	0.8	-0.2	0.7	-0.2	-0.1	-0.1	-0.1	-0.1	0.2	-0.2	0.3	-0.6	-0.5	-0.1	-0.6	0.3	-0.1
Knee pain experienced in last month	0.1	0.1	0.5	0.1	-0.1	0.2	0.1	0.2	0.4	0.2	0.1	0.1	-0.1	0.1	-0.4	-0.4	-0.7	0.2	-0.7	0.6	-0.1
Whole body fat-free mass	0.1	0.3	1.1	0.4	1.1	0.4	0.5	0.1	0.5	0.4	0.4	1.0	0.2	0.4	-0.1	-0.7	0.6	0.5	-0.8	-0.1	0.6
Eye problems/disorders: Cataract	0.1	0.1	0.5	0.0	-0.0	0.0	-0.7	-0.5	0.2	-0.0	0.0	-0.3	-0.2	-0.2	-0.4	0.3	-0.4	0.5	0.2	-0.5	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	1.8	0.1	-0.1	0.1	0.3	-0.9	0.3	0.2	0.1	0.1	0.3	0.2	0.7	0.7	0.3	1.3	0.8	0.0	0.2
Whole body water mass	0.1	0.3	1.2	0.5	1.1	0.5	0.5	0.1	0.6	0.5	0.5	1.1	0.2	0.4	0.0	-0.6	0.7	0.5	-0.7	-0.1	0.6
Miserableness	0.1	0.2	0.9	-0.4	-0.6	-0.3	-0.6	-0.7	-0.4	-0.3	-0.4	-0.1	-0.2	-0.3	0.2	0.0	-0.3	0.9	-0.2	-0.9	-0.1
Wears glasses or contact lenses	0.1	0.1	0.9	0.3	-0.5	0.3	0.4	-0.3	0.2	0.3	0.3	-0.0	0.2	0.3	0.2	0.6	0.0	-0.4	0.9	0.4	0.1
Ever taken oral contraceptive pill	0.1	0.2	0.6	0.3	0.1	0.2	0.3	-0.4	0.5	0.2	0.3	0.6	0.8	0.4	-0.1	-0.1	0.0	-0.3	-0.2	0.7	0.4
Medication: Paracetamol	0.1	0.2	0.9	0.3	-0.1	0.4	0.1	-0.5	0.4	0.4	0.3	0.4	0.5	0.4	-0.0	0.0	0.3	1.0	0.7	0.4	0.3
Basal metabolic rate	0.1	0.5	1.5	0.8	1.0	0.7	0.8	0.0	0.8	0.7	0.8	1.2	0.5	0.7	0.2	-0.5	0.8	0.8	-0.5	0.2	0.8
Number of operations (self-reported)	0.1	0.2	0.5	0.4	0.7	0.4	0.3	0.7	0.4	0.4	0.4	-0.2	0.7	0.3	0.6	0.4	0.3	0.4	0.2	0.6	0.1
Pack years of smoking	0.1	0.2	0.9	0.4	-0.7	0.3	-1.0	0.1	0.3	0.3	0.4	-0.0	0.1	0.3	-0.6	-0.5	-0.1	0.2	-0.4	0.4	-0.0
Hair Pigment	0.0	1.0	5.2	0.7	-0.6	0.7	-0.4	-0.4	0.4	0.8	0.7	0.0	-0.6	0.7	1.4	2.0	1.1	-0.7	2.3	0.8	0.8
Tanning	0.0	0.5	0.9	0.8	0.4	0.8	-0.3	0.3	0.7	0.8	0.8	0.5	0.9	0.7	0.7	0.9	0.6	0.9	0.9	0.3	0.8
Allergy	0.0	0.1	0.1	-0.3	-0.0	-0.2	0.0	-0.0	-0.4	-0.2	-0.3	-0.2	0.4	-0.4	0.0	-0.3	-0.1	0.4	0.0	-0.4	-0.2
Trunk fat-free mass	0.0	0.2	1.0	0.1	0.9	0.0	0.4	0.0	0.1	0.0	0.1	0.8	-0.2	0.1	-0.1	-0.9	0.4	0.2	-1.0	-0.5	0.3
Trunk predicted mass	0.0	0.2	1.0	0.0	0.9	-0.0	0.2	0.0	0.0	-0.0	0.0	0.7	-0.3	-0.0	-0.2	-0.9	0.3	0.2	-1.0	-0.6	0.2
Shortness of breath walking on level ground	0.0	0.0	0.3	0.1	0.4	0.1	0.1	0.2	0.2	0.1	0.1	-0.2	0.2	0.0	0.1	0.4	-0.0	0.0	0.5	-0.0	-0.0
Leg fat-free mass (right)	0.0	0.3	0.8	0.4	0.9	0.4	0.3	0.1	0.5	0.4	0.4	0.9	0.3	0.3	-0.5	-0.7	0.4	0.5	-0.9	-0.1	0.4
Leg predicted mass (right)	0.0	0.2	0.9	0.3	0.8	0.3	0.2	0.0	0.4	0.3	0.3	0.8	0.2	0.2	-0.6	-0.8	0.3	0.3	-1.0	-0.2	0.3
Average weekly champagne plus white wine intake	0.0	0.1	0.5	0.2	0.1	0.2	-0.7	-0.2	0.1	0.3	0.2	0.4	-0.1	0.1	0.1	0.3	0.1	-0.2	0.2	0.1	0.2
Illnesses of father: High blood pressure	0.0	0.1	0.1	-0.1	0.0	-0.0	0.1	0.4	-0.2	-0.1	-0.1	0.3	-0.3	0.1	0.3	0.1	-0.2	-0.3	0.3	0.3	0.2

Hub : Genes

SUPT4H1

Models

Trait associations