[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr17:65,123,352-66,885,526

Best TWAS P=1.06e-38 · Best GWAS P=6.21e-39 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	LINC00674	0.12	0.13	enet	6	0.14	9.9e-12	11.7	12.3	6.8e-35	0.79	0.97	0.03	TRUE
2	GTEx	Adipose Subcutaneous	LRRC37A16P	0.10	0.10	enet	10	0.14	2.9e-11	11.9	8.4	3.7e-17	0.60	0.96	0.03	TRUE
3	GTEx	Adipose Subcutaneous	SH3GL1P3	0.08	0.06	lasso	5	0.04	2.5e-04	11.7	11.6	3.2e-31	0.80	0.08	0.87	FALSE
4	GTEx	Adipose Subcutaneous	RP11-147L13.8	0.28	0.09	enet	27	0.23	9.7e-19	7.1	7.1	9.2e-13	0.46	1.00	0.00	FALSE
5	GTEx	Adipose Visceral Omentum	LINC00674	0.29	0.03	enet	40	0.03	6.9e-03	10.6	8.2	2.9e-16	0.63	0.08	0.52	FALSE
6	GTEx	Artery Aorta	LINC00674	0.12	0.00	lasso	5	0.01	1.5e-01	7.1	9.2	3.6e-20	0.58	0.08	0.33	FALSE
7	GTEx	Artery Aorta	RP11-147L13.8	0.17	0.10	lasso	6	0.06	4.1e-04	7.1	7.0	3.3e-12	0.46	0.43	0.02	FALSE
8	GTEx	Brain Cerebellum	BPTF	0.22	-0.01	lasso	10	-0.01	6.9e-01	9.3	-10.3	5.3e-25	-0.85	0.03	0.48	FALSE
9	GTEx	Brain Cortex	C17orf58	0.34	0.09	lasso	6	0.13	2.4e-04	12.9	12.6	3.1e-36	0.95	0.03	0.96	FALSE
10	GTEx	Cells Transformed fibroblasts	LINC00674	0.30	0.31	enet	10	0.32	1.5e-24	11.7	11.9	7.6e-33	0.86	1.00	0.00	FALSE
11	GTEx	Cells Transformed fibroblasts	LRRC37A16P	0.50	0.46	lasso	8	0.47	1.1e-38	11.7	11.9	7.4e-33	0.84	1.00	0.00	FALSE
12	GTEx	Cells Transformed fibroblasts	SH3GL1P3	0.26	0.31	lasso	7	0.31	1.5e-23	11.7	12.7	1.0e-36	0.90	0.98	0.02	FALSE
13	GTEx	Colon Sigmoid	LINC00674	0.42	0.09	lasso	8	0.12	5.5e-05	10.6	10.9	7.8e-28	0.80	0.16	0.64	FALSE
14	GTEx	Colon Sigmoid	RP11-147L13.8	0.12	0.20	lasso	3	0.15	4.4e-06	7.1	7.6	2.5e-14	0.51	0.32	0.51	FALSE
15	GTEx	Esophagus Mucosa	LRRC37A16P	0.11	0.06	enet	13	0.08	7.5e-06	7.9	-8.4	4.7e-17	-0.67	0.13	0.81	FALSE
16	GTEx	Esophagus Muscularis	LINC00674	0.11	0.04	lasso	6	0.07	7.9e-05	7.1	10.2	1.8e-24	0.77	0.14	0.83	FALSE
17	GTEx	Esophagus Muscularis	LRRC37A16P	0.12	0.03	enet	21	0.02	3.2e-02	13.0	9.5	1.6e-21	0.64	0.02	0.82	TRUE
18	GTEx	Heart Atrial Appendage	LINC00674	0.14	0.08	lasso	17	0.09	1.1e-04	7.0	10.2	1.3e-24	0.73	0.05	0.88	FALSE
19	GTEx	Lung	LINC00674	0.14	0.03	enet	22	0.08	2.1e-06	12.9	9.5	2.0e-21	0.80	0.11	0.89	TRUE
20	GTEx	Muscle Skeletal	LRRC37A16P	0.14	0.04	lasso	5	0.08	3.3e-08	7.1	-8.0	1.0e-15	-0.59	0.99	0.00	FALSE
21	GTEx	Nerve Tibial	LINC00674	0.09	0.01	enet	13	0.03	2.2e-03	7.1	9.0	2.2e-19	0.65	0.21	0.20	FALSE
22	GTEx	Nerve Tibial	LRRC37A16P	0.09	0.08	lasso	4	0.06	2.7e-05	11.9	12.0	3.6e-33	0.84	0.09	0.81	FALSE
23	GTEx	Skin Sun Exposed Lower leg	BPTF	0.10	0.01	enet	14	0.03	2.7e-03	10.5	-9.9	6.2e-23	-0.69	0.06	0.75	FALSE
24	GTEx	Spleen	C17orf58	0.30	-0.01	lasso	8	-0.01	4.6e-01	8.5	12.5	9.3e-36	0.81	0.03	0.34	TRUE
25	GTEx	Stomach	RP11-147L13.8	0.23	-0.01	enet	9	0.01	8.1e-02	5.3	9.4	5.6e-21	0.57	0.04	0.20	FALSE
26	GTEx	Thyroid	LINC00674	0.09	0.10	enet	16	0.12	4.0e-09	7.1	7.9	2.3e-15	0.61	0.53	0.43	FALSE
27	GTEx	Thyroid	SH3GL1P3	0.08	0.00	lasso	3	0.00	2.8e-01	7.1	8.1	4.3e-16	0.56	0.05	0.47	FALSE
28	GTEx	Thyroid	RP11-147L13.8	0.23	0.17	lasso	3	0.16	3.5e-12	7.1	7.3	2.4e-13	0.49	1.00	0.00	FALSE
29	YFS	Blood	KPNA2	0.01	0.01	blup	312	0.01	2.8e-04	10.6	-11.3	1.2e-29	-0.86	0.05	0.93	FALSE
30	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	LOC651250	0.02	0.02	blup	2	0.03	1.9e-03	6.0	-7.6	2.2e-14	-0.51	0.00	0.64	FALSE
31	The Cancer Genome Atlas	Breast Invasive Carcinoma	LOC651250	0.01	0.01	lasso	1	0.01	1.5e-03	6.0	-6.0	1.7e-09	-0.54	0.00	0.80	FALSE
32	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	LOC651250	0.07	0.05	lasso	1	0.05	1.8e-03	6.0	-6.0	1.7e-09	-0.54	0.00	0.77	FALSE
33	The Cancer Genome Atlas	Colon Adenocarcinoma	LOC440461	0.22	0.10	blup	10	0.12	2.8e-07	5.3	5.8	5.3e-09	0.17	0.00	1.00	TRUE
34	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LOC440461	0.11	0.05	lasso	2	0.05	5.1e-04	5.3	5.8	5.7e-09	0.17	0.00	0.84	FALSE
35	The Cancer Genome Atlas	Brain Lower Grade Glioma	LOC440461	0.22	0.14	lasso	2	0.14	1.1e-15	5.3	5.2	1.8e-07	0.16	0.00	1.00	TRUE
36	The Cancer Genome Atlas	Prostate Adenocarcinoma	LOC440461	0.06	0.01	blup	10	0.02	2.9e-03	5.3	6.3	3.3e-10	0.19	0.00	0.79	TRUE
37	The Cancer Genome Atlas	Prostate Adenocarcinoma	LOC651250	0.03	0.02	enet	2	0.02	2.0e-03	6.0	-7.3	2.3e-13	-0.55	0.00	0.77	FALSE
38	The Cancer Genome Atlas	Stomach Adenocarcinoma	LOC440461	0.10	0.00	blup	10	0.05	2.9e-04	5.3	5.5	3.0e-08	0.20	0.00	0.47	FALSE
39	The Cancer Genome Atlas	Thyroid Carcinoma	C17orf58	0.02	0.02	lasso	2	0.01	1.8e-02	13.0	13.0	1.1e-38	1.00	0.00	0.76	TRUE