TWAS hub - RPS6KB1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0380	0.0190	1.8e-03	-0.001	0.009	-0.001	0.010	0.001	4.7e-01	0.0230	0.39000	0.0170	0.26000
2	GTEx	Cells Transformed fibroblasts	0.1110	0.0450	6.2e-05	0.069	NA	0.049	NA	0.062	7.3e-06	NA	0.00014	NA	0.00002
3	GTEx	Nerve Tibial	0.0474	0.0261	8.6e-03	0.013	NA	-0.002	NA	0.004	4.0e-02	NA	0.45000	NA	0.16000
4	GTEx	Thyroid	0.1390	0.0620	1.4e-03	0.003	NA	0.020	NA	0.020	1.7e-01	NA	0.01100	NA	0.01100
5	METSIM	Adipose	0.0281	0.0151	2.5e-03	0.019	0.014	0.020	0.017	0.022	5.6e-04	0.0027	0.00042	0.0012	0.00024
6	YFS	Blood	0.0119	0.0062	1.8e-03	0.011	0.008	0.003	0.006	0.006	1.5e-04	0.0011	0.02400	0.0026	0.00460
7	TCGA	Breast Invasive Carcinoma	0.0176	0.0118	5.7e-04	0.020	0.010	0.011	NA	0.012	5.0e-05	0.0036	0.00180	NA	0.00120
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.0238	0.0162	5.2e-03	0.020	0.016	0.014	NA	0.013	2.2e-03	0.0063	0.00990	NA	0.01200
9	TCGA	Brain Lower Grade Glioma	0.0321	0.0215	4.2e-03	0.024	0.022	0.024	NA	0.020	7.7e-04	0.0013	0.00080	NA	0.00230
10	TCGA	Prostate Adenocarcinoma	0.0314	0.0204	1.6e-03	0.029	0.025	0.029	NA	0.026	4.9e-04	0.0010	0.00052	NA	0.00094

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Blood White Count	11.8	87.2	234.1	0.4	13.2	15.3	5.0	-8.9	9.2	-7.8	-8.2	8.8	-8.2
Mouth/teeth dental problems: Dentures	6.5	11.0	24.3	1.7	-4.9	-4.6	-1.0	3.3	-4.3	2.8	3.7	0.6	3.2
Qualifications: O levels/GCSEs or equivalent	6.3	10.1	22.8	-0.5	4.8	4.8	0.8	-3.5	2.7	-3.0	-3.7	0.2	-3.4
Long-standing illness, disability or infirmity	5.7	8.7	13.5	2.7	-3.5	-3.5	-0.1	3.5	-2.1	3.4	3.7	-0.4	3.6
Crohns Disease (2012)	5.6	9.0	15.3	1.0	-3.9	-3.5	-2.0	3.6	-2.7	3.2	3.4	-2.0	3.4
HbA1C	5.6	6.2	10.7	1.2	-2.7	-3.0	-0.9	3.2	-1.2	3.2	3.3	-0.7	3.2
Taking other prescription medications	5.1	7.9	15.5	3.7	-1.8	-1.6	0.6	3.8	0.0	3.7	3.9	0.5	3.9
Mouth/teeth dental problems	5.1	7.8	17.4	-1.2	4.2	3.9	1.0	-2.8	3.4	-2.5	-3.0	0.9	-2.7
Crohns Disease (2017)	4.4	9.6	14.5	0.7	-3.8	-3.8	-1.6	3.6	-2.8	3.3	3.1	-3.2	3.4
Irritable Bowel Disease (IBD)	4.1	9.7	14.6	1.3	-3.7	-3.8	-0.9	3.8	-2.6	3.8	3.5	-2.2	3.7
Systolic blood pressure, automated reading	4.1	11.8	28.5	0.3	-4.7	-5.3	-1.0	4.0	-2.4	3.5	4.1	-0.8	3.9
Past tobacco smoking	3.8	7.0	11.3	1.7	-3.1	-2.6	-2.2	3.0	-2.4	3.0	3.4	0.5	3.1
Alcohol intake frequency.	3.7	8.5	23.7	-0.4	-4.8	-4.9	-2.3	2.0	-4.1	1.5	2.1	-1.5	1.9
Ever smoked	3.6	6.3	9.6	-2.3	3.1	2.0	2.4	-2.6	2.7	-2.4	-3.1	-1.5	-2.6
Miserableness	3.4	5.9	11.6	3.0	-0.9	-1.0	0.6	3.4	1.0	3.4	2.8	-2.3	3.3
Financial situation satisfaction	3.4	4.2	10.4	-2.9	2.4	1.3	1.7	-1.5	3.2	-1.4	-1.9	-1.8	-1.4
Blood Red Count	3.3	31.8	55.5	-3.0	5.3	6.5	0.5	-7.5	3.2	-7.4	-7.1	3.5	-7.4
Overall health rating	3.3	7.1	13.2	2.4	-3.0	-2.8	-1.5	3.3	-1.4	3.0	3.6	0.7	3.4
Ever had hysterectomy (womb removed)	3.2	3.6	5.7	1.9	-2.3	-2.4	-0.2	2.2	-1.7	1.9	2.4	0.1	2.2
Medication: Atenolol	3.2	4.0	6.4	2.5	-2.1	-1.4	-0.7	1.9	-2.2	1.7	2.5	2.3	2.0
Hearing difficulty/problems with background noise	3.2	5.0	20.3	4.5	1.5	1.7	2.6	1.5	1.4	1.8	1.7	2.3	1.6
Qualifications: None of the above	3.2	6.9	12.4	2.2	-3.1	-2.7	-0.1	3.2	-2.3	2.8	3.5	1.2	3.2
Medication for cholesterol	3.2	4.8	8.2	-2.5	2.5	2.3	-1.0	-2.4	1.2	-2.1	-2.9	-1.9	-2.4
Medication: Paracetamol	3.1	5.2	9.1	2.8	-1.9	-2.1	0.4	2.9	-1.2	2.9	2.8	-0.9	3.0
Chronic bronchitis/emphysema (mother)	3.1	3.6	12.7	-0.1	-2.4	-3.6	0.7	1.7	-1.2	1.6	1.5	-2.3	1.7
Ever had bowel cancer screening	3.1	3.6	6.4	1.7	-2.2	-2.5	-0.3	2.1	-1.6	2.1	2.4	0.5	2.2
Medication: Paracetamol	3.1	4.8	8.4	2.5	-1.8	-2.1	0.9	2.8	-1.0	2.7	2.7	-1.2	2.9
Coronary Artery Disease (CAD)	3.0	3.6	7.0	2.6	-0.4	-0.6	2.2	2.3	0.0	2.4	2.4	1.0	2.4
Ulcerative Colitis	3.0	4.4	6.9	2.4	-2.2	-2.0	0.3	2.5	-1.5	2.5	2.6	0.3	2.5
Systolic Blood Pressure	3.0	14.8	30.8	0.2	-4.9	-5.5	-1.4	4.8	-2.2	4.3	4.8	-0.7	4.6
Other serious medical condition/disability diagnosed by doctor	3.0	3.9	7.2	2.5	-1.5	-1.7	-0.3	2.7	-0.5	2.5	2.7	-0.6	2.6
Impedance of leg (right)	3.0	14.6	30.5	-1.0	5.5	5.5	2.0	-4.0	4.6	-3.4	-4.2	0.7	-3.8
Mean time to correctly identify matches	3.0	5.7	9.2	1.4	-2.9	-2.6	-1.2	2.9	-2.0	2.9	3.0	-0.2	2.9
Average weekly champagne plus white wine intake	2.9	4.0	11.1	-0.4	3.2	3.3	0.8	-1.6	2.7	-1.4	-1.8	0.6	-1.7
Impedance of arm (right)	2.8	13.1	25.5	-1.3	5.0	4.6	1.6	-4.2	3.9	-3.6	-4.3	0.7	-4.0
Number of self-reported non-cancer illnesses	2.8	4.9	9.5	2.6	-1.2	-1.1	0.6	2.9	1.5	3.0	3.1	0.8	3.1
Ever taken oral contraceptive pill	2.8	3.1	5.0	-1.8	2.2	2.2	-0.1	-1.9	1.8	-1.8	-2.1	-0.1	-2.0
Intelligence (Savage-Jansen 2018)	2.7	8.3	15.7	-1.4	3.6	3.4	-0.1	-3.6	1.9	-3.2	-4.0	-0.9	-3.6
Impedance of leg (left)	2.6	12.5	24.0	-1.2	4.9	4.9	1.5	-3.9	3.8	-3.5	-4.1	0.7	-3.8
Mother’s age at death	2.6	3.3	7.7	0.6	2.8	2.6	1.9	-1.6	2.4	-1.0	-1.6	0.8	-1.4
Primary Biliary Cirrhosis	2.5	3.6	5.9	2.2	-1.9	-2.1	-0.4	2.3	-1.0	2.3	2.4	-0.2	2.4
Number of treatments/medications taken	2.5	4.5	9.0	2.4	-0.7	-0.6	1.2	2.9	1.4	3.0	2.9	0.6	3.0
High blood pressure (mother)	2.5	3.5	5.9	0.8	-0.7	-2.1	1.6	2.3	1.1	2.4	1.8	-2.4	2.3
Loud music exposure frequency	2.5	2.8	6.2	1.4	-1.4	-1.2	-0.6	2.5	-1.0	2.1	2.3	-0.8	2.3
Impedance of whole body	2.5	12.6	22.6	-1.3	4.8	4.7	1.4	-4.1	3.8	-3.6	-4.2	0.6	-3.9
Breast Cancer	2.4	5.8	11.2	2.8	0.1	-1.0	2.4	3.1	1.9	3.4	2.7	-1.5	3.1
Neuroticism	2.4	5.7	10.0	2.4	-2.1	-2.2	-0.2	3.2	-1.3	3.0	2.8	-1.9	3.1
Seen doctor (GP) for nerves, anxiety, tension or depression	2.4	3.6	6.9	1.6	-1.4	-2.0	-0.2	2.6	0.0	2.6	2.2	-1.9	2.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.4	2.8	10.0	3.2	-1.0	-0.0	-0.8	0.8	-2.3	0.9	1.4	2.7	0.9
Reaction Time	2.3	4.4	7.5	1.6	-2.2	-2.2	-0.4	2.7	-1.4	2.7	2.7	-0.5	2.7
Diabetes (father)	2.3	2.8	10.6	0.6	2.1	2.4	3.3	-0.3	2.4	0.1	-0.3	1.1	-0.1
Impedance of arm (left)	2.3	10.6	18.8	-1.2	4.3	4.2	1.5	-3.8	3.7	-3.3	-3.9	0.5	-3.6
Reason for reducing amount of alcohol drunk: Health precaution	2.3	2.7	5.0	0.4	2.1	1.9	2.2	-1.3	2.2	-1.0	-1.1	2.0	-1.1
Medication: Blood pressure	2.3	4.5	7.8	2.6	-2.0	-2.4	0.7	2.6	-0.1	2.4	2.8	0.6	2.6
Alcohol drinker status: Never	2.3	2.8	5.1	0.6	-2.3	-2.0	-1.6	1.9	-1.3	1.6	1.7	-1.4	1.8
Chronotype (morning person)	2.2	5.0	10.7	2.4	-1.3	-1.2	0.0	2.8	-1.1	2.7	3.3	2.4	2.8
Sensitivity / hurt feelings	2.2	3.8	12.4	0.4	-2.0	-3.5	0.5	1.8	-1.5	1.7	1.4	-2.9	1.7
Headache pain in last month	2.2	3.7	7.7	2.2	-0.0	-0.2	1.6	2.7	0.5	2.8	2.4	-1.0	2.8
Seen a psychiatrist for nerves, anxiety, tension or depression	2.2	2.9	6.2	0.9	-0.3	-1.0	0.6	2.4	1.0	2.5	1.9	-2.1	2.3
Unable to work because of sickness or disability	2.2	2.8	6.0	0.5	-2.4	-2.5	-1.1	1.8	-1.7	1.6	1.8	-0.9	1.6
Pain experienced in last month	2.2	3.7	9.4	-3.1	0.1	0.3	-1.9	-2.3	-0.7	-2.5	-2.2	0.5	-2.5
Alzheimer’s Disease (in father)	2.1	2.3	6.2	-0.5	2.0	1.8	2.2	-1.0	2.5	-0.6	-1.3	-0.2	-1.0
Heart attack	2.1	2.6	6.4	2.5	-0.3	0.0	1.4	1.8	0.4	1.9	2.1	1.6	2.0
Emphysema/chronic bronchitis	2.1	2.4	6.2	0.4	-2.2	-1.9	-2.5	1.0	-2.0	0.7	1.4	1.0	0.9
Medication for pain relief, constipation, heartburn	2.1	3.6	9.1	-3.0	-0.1	-0.0	-1.1	-2.5	-0.9	-2.5	-2.4	-0.5	-2.5
Illnesses of father: Heart disease	2.1	3.0	9.1	1.6	2.1	2.1	2.8	-0.1	3.0	0.3	0.0	1.3	0.2
Smoking status: Previous	2.1	3.2	5.5	-1.0	1.8	1.9	1.2	-2.2	1.4	-2.3	-2.3	0.2	-2.3
Heart attack/myocardial infarction (self-reported)	2.1	2.7	6.6	2.6	-0.4	-0.1	1.2	1.9	0.3	2.0	2.2	1.5	2.1
Ulcerative Colitis (UC)	2.0	3.7	7.3	1.9	-1.6	-1.8	0.8	2.5	-0.7	2.7	2.5	-0.3	2.5
Blood Eosinophil Count	2.0	15.1	57.5	7.6	2.6	3.9	1.9	2.7	2.0	3.4	3.3	5.0	3.1
Blood Platelet Count	2.0	23.1	80.1	-2.1	7.3	8.9	0.9	-4.0	5.6	-3.1	-4.3	1.3	-3.9
Ever used hormone-replacement therapy (HRT)	2.0	2.6	5.2	0.9	-2.0	-2.3	1.6	1.7	-0.7	1.4	2.0	0.8	1.8
Handedness (chirality/laterality): Left-handed	2.0	2.5	5.6	-1.5	0.7	0.2	-0.6	-2.2	-0.2	-2.2	-2.4	-1.0	-2.2
Major Depression (MDD)	1.9	2.3	10.1	0.1	2.2	1.3	3.2	-0.3	2.3	-0.2	-0.7	-0.6	-0.4
Lung FEV1/FVC ratio	1.9	9.6	16.2	2.7	-3.4	-3.1	-0.5	4.0	-2.1	3.9	4.0	-0.5	3.9
Hand grip strength (right)	1.9	5.1	10.5	-2.1	1.8	2.4	-0.2	-2.9	0.3	-2.9	-3.2	-0.8	-3.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.9	2.6	5.2	0.7	-1.4	-2.0	0.0	2.0	-0.3	1.9	1.7	-2.3	1.9
Hair/balding pattern: Pattern 2	1.9	2.4	5.0	-0.6	1.5	2.2	-1.7	-1.8	1.1	-1.7	-1.7	0.6	-1.7
Fluid intelligence score	1.9	3.8	7.3	-1.7	2.0	1.9	-1.2	-2.4	1.3	-2.0	-2.7	-1.6	-2.3
Schizophrenia vs Biploar Disorder	1.8	2.4	4.5	-2.1	1.4	1.1	0.6	-1.6	1.6	-1.5	-1.9	-1.7	-1.6
Ovarian Cancer	1.8	2.3	4.1	-1.5	0.4	1.6	-0.9	-2.0	0.3	-2.0	-1.7	1.5	-2.0
Severe depression (siblings)	1.8	2.0	5.9	-2.2	1.1	0.5	-0.1	-1.0	1.6	-1.1	-1.5	-2.4	-1.1
Townsend deprivation index at recruitment	1.8	2.6	5.2	1.5	-2.1	-2.3	-0.7	1.4	-2.2	1.1	1.7	0.5	1.4
Relative age voice broke	1.8	2.7	9.8	0.6	3.1	2.7	1.4	-0.7	2.3	-0.3	-1.0	-0.2	-0.7
Nervous feelings	1.8	3.4	5.2	1.4	-2.0	-2.2	-0.5	2.3	-2.0	2.0	2.0	-1.3	2.1
Time employed in main current job	1.8	2.1	6.2	-0.1	-2.5	-2.0	-1.2	1.3	-1.6	0.9	1.3	-0.8	1.2
Medication: Ibuprofen (e.g. Nurofen)	1.8	2.3	7.4	0.8	1.9	1.0	2.7	0.9	2.7	1.0	0.6	0.1	0.9
Forced vital capacity (FVC), Best measure	1.8	6.5	11.5	0.2	2.5	3.0	0.3	-3.4	0.3	-3.4	-3.0	2.5	-3.4
Back pain experienced in last month	1.8	2.7	8.7	2.9	-0.7	-0.3	1.1	1.7	-0.4	1.6	2.1	1.8	1.8
Hearing aid user	1.8	2.0	5.0	2.2	-0.7	-0.2	1.0	1.4	-0.8	1.4	1.8	2.0	1.4
Medication: Lisinopril	1.8	2.3	4.2	1.4	0.2	0.4	0.9	2.0	1.8	2.0	2.0	0.7	2.0
Irritability	1.8	3.0	5.3	2.2	-0.9	-1.4	0.5	2.3	-0.9	2.2	2.0	-1.5	2.2
Heart disease (siblings)	1.8	2.2	6.5	2.5	-0.5	-0.6	1.2	1.7	0.0	1.9	1.8	0.6	1.8
Lupus	1.7	2.6	4.3	1.8	-1.9	-1.7	-0.4	1.9	-0.9	1.9	2.0	0.2	2.1
Chronic bronchitis/emphysema (father)	1.7	1.9	9.5	-1.0	-1.1	-2.4	-0.1	0.9	0.0	0.8	0.3	-3.1	0.7
Alcohol usually taken with meals	1.7	2.8	6.5	-1.2	2.5	2.1	1.0	-1.3	2.5	-0.9	-1.7	-1.2	-1.3
Forced vital capacity (FVC)	1.7	6.7	13.4	-0.6	2.0	2.7	-0.4	-3.7	-0.5	-3.7	-3.2	2.2	-3.6
Medication: Seretide 50 evohaler	1.7	2.0	6.3	-0.8	-2.5	-2.3	-1.3	1.1	-1.1	0.8	1.1	-0.9	1.0
Heart disease (mother)	1.7	2.1	6.7	1.3	2.0	1.4	1.9	0.3	2.6	0.7	0.4	1.4	0.5
Medication: Aspirin	1.7	2.3	6.0	2.4	0.3	1.5	-0.6	1.2	1.0	1.4	1.6	2.3	1.3
Fractured/broken bones in last 5 years	1.7	2.2	4.5	-0.8	1.4	1.4	-0.1	-2.0	0.4	-2.0	-2.1	-0.4	-2.0
Pack years of smoking	1.7	2.5	9.9	0.1	-2.6	-1.2	-3.1	0.6	-2.2	0.4	0.9	0.3	0.6
Smoking Status	1.6	3.9	8.0	-1.9	1.7	1.4	0.5	-2.4	1.0	-2.6	-2.8	-1.5	-2.5
Hand grip strength (left)	1.6	4.1	8.9	-2.0	1.2	1.5	-0.1	-2.7	-0.4	-2.7	-3.0	-0.9	-2.9
Hearing difficulty/problems: Yes	1.6	2.4	8.1	2.8	-0.2	0.0	2.3	1.2	-0.2	1.3	1.6	1.8	1.3
Relative age of first facial hair	1.6	3.2	9.1	0.1	2.9	3.0	0.1	-1.3	2.8	-1.0	-1.4	0.6	-1.3
Average weekly fortified wine intake	1.6	1.9	3.4	-1.7	1.0	1.3	0.4	-1.7	0.7	-1.8	-1.7	0.4	-1.8
Neuroticism score	1.6	3.3	6.3	1.7	-1.6	-1.9	0.2	2.3	-0.8	2.0	1.8	-2.5	2.1
Peak expiratory flow (PEF)	1.6	3.8	11.3	0.7	2.4	3.4	0.7	-1.9	1.3	-1.8	-1.8	2.1	-1.9
Commuting to job workplace: Walk	1.6	1.8	3.8	1.4	1.1	-0.1	1.9	1.2	1.7	1.6	0.9	-1.2	1.3
Mouth/teeth dental problems: Mouth ulcers	1.6	2.5	11.3	-1.3	-2.0	-2.3	-0.6	0.8	-1.1	0.6	0.3	-3.4	0.6
Medication: Aspirin	1.6	2.0	7.1	2.3	0.4	1.5	-0.5	0.9	0.9	1.0	1.3	2.7	1.0
Illnesses of father: None of the above (group 1)	1.6	2.0	7.7	-0.8	-1.7	-1.2	-2.6	-0.3	-2.8	-0.6	-0.2	-0.5	-0.3
Depressed Affect (Nagel 2018)	1.5	3.2	7.5	2.7	-1.1	-0.8	0.3	2.3	0.5	2.3	2.1	-1.2	2.4
Verbal and Numeric Reasoning (VNR)	1.5	3.5	6.8	-0.9	2.1	1.9	-1.0	-2.5	1.2	-2.1	-2.6	-0.6	-2.4
Pack years adult smoking proportion	1.5	2.3	11.2	-0.1	-2.5	-1.0	-3.3	0.5	-2.0	0.3	0.7	-0.0	0.4
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.3	3.2	1.2	-1.6	-1.4	-1.3	1.8	-1.0	1.7	1.5	-1.6	1.7
Medication: Ibuprofen	1.5	1.8	7.2	0.1	2.0	1.2	2.3	0.3	2.7	0.4	0.1	0.4	0.3
Eye problems/disorders: Diabetes related eye disease	1.4	1.5	3.9	0.5	1.6	2.0	1.2	-1.0	1.8	-0.7	-0.9	1.1	-0.8
Number of incorrect matches in round	1.4	2.3	4.8	2.2	-0.1	-0.4	1.7	1.8	0.2	1.9	1.9	0.7	2.0
Number of live births	1.4	2.0	3.3	1.4	-1.6	-1.8	0.5	1.4	-1.2	1.3	1.8	1.3	1.6
Birth weight of first child	1.4	2.5	4.0	-0.1	-1.7	-2.0	-1.3	1.7	-1.8	1.8	1.7	-1.0	1.7
Neck or shoulder pain in last month	1.4	2.0	6.0	1.8	2.1	2.4	1.3	0.1	1.9	0.3	-0.0	0.4	0.3
Average weekly red wine intake	1.4	2.0	3.7	1.3	1.0	0.7	1.9	1.5	1.5	1.9	1.5	0.7	1.6
Age started oral contraceptive pill	1.4	1.8	5.0	2.2	-0.9	-0.4	-0.1	1.1	-0.5	1.1	1.6	2.2	1.3
Diastolic blood pressure, automated reading	1.4	4.3	10.3	-0.4	-2.9	-3.2	-1.4	2.3	-1.7	1.8	2.4	-0.6	2.2
Vascular/heart problems diagnosed by doctor	1.4	3.9	7.1	-1.5	1.0	1.6	-1.7	-2.6	-1.4	-2.6	-2.6	-0.2	-2.7
Type 2 Diabetes (T2D) (2012)	1.3	1.5	5.4	0.4	1.6	1.4	2.3	-0.5	1.8	-0.2	-0.5	1.1	-0.4
High blood pressure	1.3	3.5	5.9	1.2	-1.4	-2.3	1.7	2.4	1.1	2.3	2.4	-0.1	2.4
Exposure to tobacco smoke at home	1.3	1.4	4.3	-2.1	-0.3	-0.3	-1.7	-1.1	-0.9	-1.4	-1.0	-0.2	-1.2
Angina (self-reported)	1.3	1.7	3.3	1.4	1.2	1.7	1.6	1.0	1.8	1.1	1.0	0.6	1.1
Ever had stillbirth, spontaneous miscarriage or termination	1.3	1.4	4.5	-0.3	2.1	1.4	0.9	-1.0	1.6	-0.8	-1.2	-0.2	-1.0
Osteoporosis (self-reported)	1.3	1.7	4.7	-0.7	-1.5	-1.3	-2.2	1.3	-0.6	1.2	1.1	-1.2	1.2
Medication: Gliclazide	1.3	1.5	7.3	1.6	1.4	0.5	2.7	0.5	1.1	0.8	0.4	0.4	0.7
Tinnitus: Yes, now most or all of the time	1.3	1.6	5.7	0.2	1.4	1.8	2.4	-0.6	1.7	-0.6	-0.7	0.5	-0.6
Ever depressed for a whole week	1.3	1.6	7.0	-1.0	-1.1	-2.0	1.1	0.9	-0.1	0.6	0.3	-2.6	0.7
Neuroticism (Nagel 2018)	1.2	2.8	6.9	2.6	-0.7	-1.1	0.9	2.1	-0.1	2.1	1.8	-1.2	2.2
Alzheimer’s Disease (in mother)	1.2	1.5	2.4	-1.1	0.4	1.2	-1.1	-1.6	-0.4	-1.6	-1.3	1.3	-1.5
Lung FVC	1.2	6.3	14.7	-1.3	1.6	1.9	-0.1	-3.7	0.2	-3.8	-3.4	1.4	-3.7
Supplements: Glucosamine	1.2	1.5	5.3	1.0	2.0	2.1	0.3	-0.4	2.3	-0.3	-0.5	0.4	-0.4
Medication: Levothyroxine sodium	1.2	2.1	3.8	1.2	-1.8	-1.3	-1.1	1.6	-0.6	1.4	1.9	1.3	1.6
Ever unenthusiastic/disinterested for a whole week	1.2	1.4	3.4	-0.8	-0.3	-1.1	1.8	1.2	1.1	1.1	0.7	-1.9	1.1
Medication: Ramipril	1.2	1.5	5.5	2.3	-0.6	-0.0	-0.3	1.2	0.5	1.4	1.5	1.3	1.4
Hair/balding pattern: Pattern 3	1.2	1.7	3.3	1.0	-1.2	-1.8	1.0	1.3	-1.3	1.5	1.6	0.5	1.3
Medication: Cholesterol lowering	1.2	1.8	3.5	1.1	1.3	1.4	1.9	1.1	1.6	1.2	1.1	1.4	1.1
Depression (self-reported)	1.2	1.4	6.6	0.3	-0.9	-1.4	0.6	1.1	-0.3	1.1	0.7	-2.6	1.0
Length of working week for main job	1.2	1.3	2.4	-0.8	1.5	1.4	0.9	-1.2	1.2	-1.1	-1.2	-0.0	-1.2
Tense / ‘highly strung’	1.2	2.0	4.4	0.8	-1.0	-1.2	0.4	2.1	-0.5	1.9	1.9	-0.9	1.9
Exposure to tobacco smoke outside home	1.2	1.6	7.1	-1.3	-1.3	-2.1	-0.7	0.5	-0.4	0.1	0.1	-2.7	0.2
Osteoarthritis (self-reported)	1.2	1.5	2.9	1.4	-0.8	-0.8	0.6	1.7	0.8	1.6	1.6	-0.4	1.7
Depression (Nagel 2018)	1.1	1.6	2.9	1.1	-0.4	-0.8	0.6	1.7	1.0	1.7	1.3	-1.7	1.7
Angina	1.1	1.4	3.3	1.3	1.1	1.8	1.3	0.8	1.7	0.8	0.8	1.0	0.8
Illnesses of mother	1.1	1.4	8.8	-0.2	-1.4	-0.6	-1.4	-0.3	-3.0	-0.7	-0.1	0.6	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.4	5.7	1.1	1.7	2.4	0.2	-2.2	-0.2	-2.3	-1.9	2.4	-2.2
Gout (self-reported)	1.1	1.5	4.5	-0.9	-2.1	-1.8	-1.0	0.6	-1.9	0.4	0.6	-0.5	0.5
Age at last live birth	1.1	1.6	3.3	1.6	-0.8	0.3	-1.2	1.2	-0.9	1.2	1.6	1.8	1.3
Qualifications: nursing, teaching	1.1	1.7	3.1	-1.4	1.5	1.7	-0.9	-1.1	1.7	-1.0	-1.4	-0.6	-1.2
Medication: Atorvastatin	1.1	1.3	7.2	0.4	0.9	2.0	-0.1	-0.4	0.7	-0.4	0.0	2.7	-0.4
Basal cell carcinoma (self-reported)	1.1	1.4	3.2	-0.5	0.8	0.1	0.8	-1.7	-0.1	-1.8	-1.6	0.6	-1.7
Triglycerides	1.0	1.6	3.4	1.6	-0.3	-0.9	0.6	1.7	-0.2	1.8	1.7	0.1	1.8
BMI	1.0	5.5	14.2	-0.8	-3.8	-3.5	-2.1	2.3	-2.3	1.7	2.2	-1.1	2.0
Forced expiratory volume in 1-second (FEV1)	1.0	3.2	6.3	0.2	1.1	1.9	-0.2	-2.5	-0.7	-2.5	-2.2	1.6	-2.5
Pulse rate	1.0	1.8	3.4	-1.0	0.9	1.1	-0.8	-1.9	1.0	-1.7	-1.8	0.4	-1.8
Shortness of breath walking on level ground	1.0	1.2	2.4	1.5	-1.4	-0.3	-0.5	1.0	-1.6	0.7	1.2	1.2	0.9
Comparative height size at age 10	1.0	5.6	17.9	4.1	-1.7	0.1	-1.6	1.5	-1.9	1.5	2.4	4.2	1.7
Suffer from ‘nerves’	1.0	1.6	3.9	2.0	-0.9	-0.5	-0.6	1.4	-1.7	1.3	1.3	-0.7	1.4
Hypertension (Self-reported)	1.0	2.7	4.5	1.1	-0.9	-1.6	1.7	2.1	1.4	2.0	2.1	-0.0	2.1
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.2	3.7	-0.1	0.8	1.5	-0.5	-1.9	-1.4	-1.8	-1.6	1.9	-1.9
Guilty feelings	1.0	1.5	3.2	-0.8	1.4	1.2	-0.3	-1.2	1.8	-1.2	-1.5	-1.3	-1.2
Bipolar Disorder (2018)	0.9	1.4	2.4	1.2	-1.0	-0.9	-0.7	1.5	-1.2	1.3	1.6	0.6	1.4
Worry (Nagel 2018)	0.9	1.9	2.8	1.4	-1.4	-1.5	0.6	1.7	-1.4	1.5	1.6	-0.6	1.7
Prostate Cancer	0.9	1.3	2.4	-1.6	-0.6	-1.3	-0.3	-1.2	-1.2	-1.4	-1.2	-0.8	-1.2
Bipolar Disorder (2011)	0.9	0.9	2.8	0.9	1.3	0.8	1.7	0.4	1.2	0.6	0.3	0.3	0.5
Respiratory disease	0.9	1.9	3.9	2.0	-1.5	-1.1	-1.1	1.5	-1.1	1.4	1.6	0.2	1.6
Frequency of depressed mood in last 2 weeks	0.9	1.3	9.8	0.0	-0.1	-0.7	-0.3	0.9	0.8	0.8	0.2	-3.1	0.8
Supplements: Zinc	0.9	1.0	4.0	2.0	-0.5	-0.1	0.2	1.1	0.3	1.3	1.1	0.2	1.1
Number of full sisters	0.9	1.1	6.4	-0.8	0.4	-0.9	2.5	-0.5	0.9	-0.5	-0.6	-1.1	-0.4
Commuting to job workplace: Public transport	0.9	1.1	2.3	0.3	-0.6	-1.5	-0.1	1.1	-0.5	1.5	0.9	-1.5	1.2
Alzheimer’s Disease (including proxy)	0.8	1.1	2.5	-0.8	0.9	1.6	0.0	-1.2	1.0	-1.1	-1.1	1.0	-1.2
Allergy or Eczema	0.8	2.1	7.8	2.8	0.9	1.1	1.7	0.5	0.5	0.9	0.9	2.5	0.7
Type 2 Diabetes (T2D) (2018)	0.8	1.6	4.4	-0.4	1.9	1.7	1.6	-0.7	2.1	-0.6	-0.8	0.2	-0.6
Medication: Co-codamol	0.8	1.0	1.7	1.2	-1.1	-1.3	-0.6	1.0	-0.4	1.2	1.1	-0.0	1.1
Qualifications: A levels/AS levels or equivalent	0.8	1.8	3.1	-1.3	1.8	1.3	-1.3	-1.4	1.0	-1.0	-1.7	-1.0	-1.4
Hair/balding pattern: Pattern 4	0.8	1.9	3.5	1.2	-1.9	-1.8	0.0	1.3	-1.4	1.1	1.7	1.3	1.3
Hypothyroidism/myxoedema (self-reported)	0.8	1.6	3.3	1.4	-1.8	-1.2	-1.0	1.2	-0.7	1.1	1.5	1.1	1.3
Qualifications: College or University degree	0.8	2.4	6.6	-1.1	2.6	2.4	-0.5	-1.2	1.8	-0.7	-1.5	-1.2	-1.2
Chest pain or discomfort	0.8	1.2	4.8	0.4	1.5	1.1	0.9	0.6	2.2	0.8	0.3	-1.1	0.7
Loneliness, isolation	0.8	1.2	3.1	1.7	0.1	0.4	0.2	1.3	1.2	1.4	1.2	-0.0	1.4
Leg predicted mass (right)	0.8	4.0	10.7	0.9	-3.0	-2.5	-1.7	1.7	-3.3	1.3	1.9	0.7	1.5
Commuting to job workplace: Cycle	0.8	0.9	3.7	0.2	-0.5	-0.9	-1.2	0.9	-0.6	0.9	0.5	-1.9	0.8
Bipolar Disorder or Schizophrenia	0.7	1.7	2.9	1.0	-0.7	-1.7	1.7	1.5	-0.2	1.5	1.6	0.3	1.5
LDL Cholesterol	0.7	1.1	3.4	0.8	1.6	1.3	1.3	0.2	1.8	0.5	0.0	-0.4	0.3
Schizophrenia (2014)	0.7	1.6	9.3	0.4	0.3	-1.4	3.0	0.8	0.9	1.0	0.8	-0.6	0.9
Bilateral oophorectomy (both ovaries removed)	0.7	0.9	1.6	0.5	-0.4	-1.0	0.1	1.2	0.8	1.2	1.0	-1.0	1.2
Stomach or abdominal pain in last month	0.7	0.8	1.6	1.1	0.0	0.6	-0.8	1.2	0.3	1.2	1.3	0.1	1.3
Illnesses of siblings	0.7	1.0	1.4	-1.2	1.0	1.1	-1.2	-1.1	0.4	-1.1	-1.2	-0.2	-1.1
Asthma	0.7	1.5	4.5	2.1	-1.1	-0.8	-1.1	1.0	-0.8	0.9	1.3	1.1	1.1
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	1.9	-0.6	-0.3	-0.6	-0.7	-1.3	-1.1	-1.4	-1.4	-1.2	-1.3
Leg fat-free mass (right)	0.7	3.7	10.0	0.9	-2.8	-2.4	-1.6	1.6	-3.2	1.2	1.9	0.8	1.4
Mood swings	0.7	1.2	4.4	0.9	-1.4	-1.3	-0.5	1.0	-0.2	0.9	0.7	-2.1	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	2.6	-0.2	1.6	1.3	1.0	-1.4	0.9	-1.3	-1.3	1.3	-1.4
Pain type(s) experienced in last month: Hip pain	0.7	0.8	1.9	1.1	0.8	1.0	1.0	0.8	1.4	0.8	0.5	-0.6	0.8
Schizophrenia (2018)	0.6	1.2	6.9	0.3	-0.1	-1.4	2.6	0.7	0.8	0.9	0.9	-0.1	0.9
Body Mass Index (BMI) (2010)	0.6	0.8	2.8	-1.6	-0.7	-0.6	-1.7	-0.3	-0.3	-0.4	-0.4	-1.0	-0.4
Hypothyroidism (self reported)	0.6	1.4	4.8	-0.3	-2.2	-1.9	-1.7	0.4	-1.3	0.2	0.6	0.2	0.4
Vitamin and mineral supplements	0.6	0.8	4.1	0.5	-1.1	-0.7	-0.2	-0.1	-2.0	-0.2	0.3	1.2	-0.0
Current tobacco smoking	0.6	0.9	5.5	-1.2	-0.2	-1.3	0.4	0.0	-0.2	-0.1	-0.4	-2.4	-0.0
Hayfever, allergic rhinitis or eczema	0.6	1.3	4.5	2.1	1.4	1.2	1.2	-0.1	0.9	0.3	0.2	1.7	0.1
Multivitamins +/- minerals	0.6	0.8	1.8	-0.9	0.9	0.6	0.8	-0.6	1.3	-0.4	-0.9	-1.4	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	4.1	-0.2	1.2	0.9	0.0	-0.1	2.0	-0.0	-0.6	-1.7	-0.1
Prospective memory result	0.6	0.8	3.1	0.2	0.2	0.0	1.8	0.8	0.6	0.6	0.9	1.3	0.7
Lung cancer (father)	0.6	0.7	2.7	-0.1	-1.0	-1.6	0.5	-0.0	-1.6	-0.4	-0.0	-0.7	-0.1
Breastfed as a baby	0.6	0.7	3.5	-1.4	0.7	-0.1	0.3	-0.2	0.8	-0.1	-0.6	-1.9	-0.3
Blood clot in the leg (DVT)	0.6	0.8	2.4	0.4	0.8	1.6	-0.6	-0.9	0.4	-0.9	-0.7	1.1	-0.8
Arm fat-free mass (right)	0.6	3.3	6.2	1.1	-2.5	-2.0	-1.2	1.9	-2.4	1.6	2.1	0.7	1.8
Wheeze or whistling in the chest in last year	0.6	1.1	3.0	1.4	-1.1	-1.0	-1.1	0.7	-1.7	0.3	1.0	0.6	0.8
Age at first live birth	0.6	1.1	2.5	1.2	-0.0	1.4	-1.6	0.5	-0.4	0.8	0.8	1.6	0.7
Medication: Allopurinol	0.6	0.8	2.7	0.1	-1.6	-1.2	-0.0	0.7	-1.4	0.6	0.8	0.6	0.7
Arm predicted mass (right)	0.6	3.1	5.8	0.9	-2.4	-2.1	-1.1	1.9	-2.3	1.6	2.0	0.2	1.7
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.0	0.1	0.7	1.4	-0.1	-0.7	0.8	-0.9	-0.5	1.2	-0.7
Knee pain experienced in last month	0.6	0.9	3.7	-0.2	0.6	0.1	0.6	0.8	1.5	0.8	0.3	-1.9	0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	3.8	1.1	0.5	0.8	0.5	0.1	0.4	0.3	0.5	1.9	0.3
Asthma (self-reported)	0.6	1.1	3.7	1.9	-0.9	-0.6	-1.3	0.8	-0.6	0.7	1.1	1.1	0.9
Wears glasses or contact lenses	0.6	0.7	2.8	0.6	1.3	1.3	0.3	0.3	1.7	0.5	0.2	0.0	0.4
Supplements: Fish oil (including cod liver oil)	0.6	0.8	2.4	0.6	0.6	-0.1	0.4	1.1	1.6	1.1	1.0	-0.2	1.1
Average weekly beer plus cider intake	0.6	0.9	3.8	0.3	-1.0	-0.9	-0.3	-0.5	-1.3	-0.8	0.1	2.0	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	2.4	0.7	0.7	1.5	-0.6	-0.8	0.2	-0.8	-0.6	1.3	-0.7
Age at First Birth	0.5	0.8	2.0	0.5	1.3	0.7	1.4	-0.7	1.1	-0.6	-0.6	0.6	-0.5
Neuroticism (2016)	0.5	0.7	1.7	0.9	-0.2	-0.7	-0.1	1.2	0.1	0.9	0.8	-1.3	1.0
Rheumatoid Arthritis	0.5	0.7	2.9	-1.7	-0.8	-0.3	-1.3	-0.4	-0.9	-0.5	-0.4	-0.2	-0.5
Tanning	0.5	5.8	10.3	2.0	-2.7	-2.5	-0.1	3.0	-1.8	2.8	3.2	0.4	3.0
Medication: Metformin	0.5	0.7	2.3	1.5	0.8	1.0	0.5	0.0	0.8	0.3	0.3	1.5	0.2
Leg fat-free mass (left)	0.5	2.8	6.2	1.1	-2.4	-1.9	-1.2	1.6	-2.5	1.3	1.8	0.8	1.4
Maternal smoking around birth	0.5	0.7	3.0	-0.3	-1.1	-1.7	0.8	0.5	-0.8	0.4	0.6	-0.4	0.5
Age when periods started (menarche)	0.5	1.2	2.3	-0.3	1.0	1.5	-0.6	-1.4	-0.9	-1.5	-1.3	0.4	-1.3
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	3.4	0.9	0.6	0.7	1.8	-0.2	0.9	0.1	-0.1	0.5	-0.0
Body mass index (BMI)	0.5	2.2	5.3	-0.2	-2.2	-2.3	-0.6	1.7	-0.9	1.3	1.7	-0.7	1.6
Leg predicted mass (left)	0.5	2.8	5.7	1.0	-2.3	-1.9	-1.2	1.6	-2.4	1.3	1.9	0.7	1.5
Had menopause	0.5	0.6	1.6	0.4	-1.2	-1.3	-0.6	0.4	-0.4	0.1	0.6	1.2	0.4
Had other major operations	0.5	0.6	1.7	0.2	0.7	0.6	-0.5	-1.0	0.3	-1.0	-0.7	1.3	-0.9
Allergy	0.5	1.2	5.5	-2.4	-0.7	-0.9	-0.2	-0.5	-0.9	-0.8	-0.8	-1.5	-0.7
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	2.7	0.1	1.6	1.2	0.3	-0.3	1.5	-0.1	-0.4	0.4	-0.2
Pulse wave reflection index	0.5	0.6	1.8	1.3	0.7	1.1	0.7	0.3	0.5	0.5	0.5	1.0	0.5
Glaucoma (self-reported)	0.5	0.6	1.3	1.1	0.4	0.8	-0.6	0.7	0.1	0.7	0.9	1.0	0.8
Medication: Amlodipine	0.5	0.7	1.3	-0.2	-1.1	-1.2	-0.8	0.9	0.3	0.8	0.9	-0.2	0.9
Worry too long after embarrassment	0.5	0.8	2.5	0.5	1.4	0.6	0.4	-0.4	1.6	-0.4	-0.8	-1.4	-0.4
Medication: Blood pressure	0.5	0.9	2.2	-0.0	-0.7	-0.5	0.2	1.4	0.5	1.3	1.5	1.0	1.3
Migraine (self-reported)	0.5	0.7	3.8	-1.0	0.2	-0.4	-0.0	-0.4	0.8	-0.2	-0.7	-1.9	-0.4
Had major operations	0.5	0.5	2.2	-0.7	0.4	-0.6	1.5	-0.8	0.6	-0.7	-0.7	0.1	-0.6
Leg pain on walking	0.5	0.6	1.8	-0.6	1.1	0.7	0.4	-0.6	1.4	-0.5	-0.8	-0.6	-0.6
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	0.9	0.8	-0.3	-0.2	1.0	0.7	-0.8	0.9	0.9	0.8	0.8
Supplements: Vitamin C	0.5	0.6	4.1	0.1	1.1	0.9	0.1	-0.1	2.0	0.2	-0.2	0.1	0.0
Friendships satisfaction	0.5	0.6	1.5	0.6	0.8	-0.4	1.2	0.6	1.2	0.5	0.3	-1.0	0.6
Smoking status: Current	0.5	0.8	4.9	-1.3	0.2	-0.9	0.4	-0.3	-0.0	-0.4	-0.7	-2.2	-0.3
Whole body water mass	0.5	2.7	5.9	0.9	-2.2	-1.8	-1.4	1.6	-2.4	1.3	1.8	0.7	1.4
Eye problems/disorders: Glaucoma	0.5	0.6	2.3	0.5	0.8	1.5	-0.1	0.2	0.3	0.2	0.4	1.4	0.3
Risk taking	0.5	0.7	2.2	-0.9	-1.5	-1.4	-0.6	0.2	-1.2	0.1	0.3	-0.4	0.1
Supplements: Calcium	0.5	0.6	1.4	1.0	0.6	1.0	0.5	0.7	1.2	0.6	0.5	-0.4	0.6
Arm predicted mass (left)	0.5	2.3	5.3	0.8	-2.1	-1.7	-1.5	1.4	-2.3	1.1	1.6	0.7	1.2
Mean Putamen Volume	0.4	0.4	0.7	-0.6	-0.8	-0.2	-0.7	-0.7	-0.8	-0.7	-0.7	-0.3	-0.7
Fasting Glucose	0.4	0.5	3.3	-0.9	0.7	0.1	0.1	0.2	0.7	-0.0	-0.2	-1.8	0.0
Cardiovascular Disease	0.4	1.2	2.5	-0.6	-0.5	-1.4	1.3	1.1	1.6	1.0	0.9	-1.1	1.2
Qualifications: CSEs or equivalent	0.4	0.5	1.0	-0.7	0.4	-0.0	1.0	-0.8	-0.5	-0.9	-0.9	-0.4	-0.8
Serious illness, injury or assault to yourself	0.4	0.5	2.1	0.3	-0.4	0.4	-1.5	-0.4	-0.3	-0.7	-0.2	1.2	-0.5
Sitting height	0.4	2.8	13.8	-0.5	-2.5	-2.2	-1.7	-0.1	-3.7	-0.4	0.2	0.0	-0.2
Financial difficulties in last 2 years	0.4	0.5	1.3	-1.0	0.4	0.4	-0.3	-0.4	1.1	-0.5	-0.7	-1.1	-0.5
Father’s age at death	0.4	0.6	1.0	-0.2	0.9	0.9	0.9	-1.0	-0.1	-0.7	-1.0	0.2	-0.9
Worrier / anxious feelings	0.4	0.8	3.2	-0.6	-0.9	-1.8	0.3	0.2	-0.9	0.1	0.0	-1.6	0.2
Happiness	0.4	0.5	2.2	-0.0	-0.4	-0.9	0.1	0.7	0.2	0.7	0.5	-1.5	0.7
Pulse wave Arterial Stiffness index	0.4	0.5	1.1	0.9	-0.2	0.3	-0.4	0.8	0.2	0.8	0.9	1.0	0.8
Comparative body size at age 10	0.4	1.2	3.0	0.8	-0.7	-0.1	-0.1	1.7	0.5	1.7	1.6	-0.1	1.6
Number of children fathered	0.4	0.5	2.2	-0.2	0.4	1.5	-0.1	-0.7	0.3	-0.7	-0.6	0.8	-0.7
Pulse wave peak to peak time	0.4	0.5	1.1	-0.7	0.2	-0.1	0.2	-0.9	-0.3	-0.9	-1.0	-0.8	-1.0
Pulse rate, automated reading	0.4	1.4	4.2	-2.0	0.0	-0.5	-1.0	-1.4	-0.3	-1.4	-1.5	-0.5	-1.4
Whole body fat-free mass	0.4	2.5	5.6	1.0	-2.1	-1.7	-1.3	1.5	-2.4	1.2	1.7	0.7	1.4
Eye problems/disorders: Cataract	0.4	0.5	1.4	-1.2	-0.9	-0.3	-0.6	-0.4	-0.8	-0.8	-0.4	0.3	-0.6
Mineral and other dietary supplements	0.4	0.5	2.5	-0.2	-0.9	-0.5	0.7	-0.4	-1.6	-0.4	-0.2	0.5	-0.3
Basal metabolic rate	0.4	2.0	4.5	0.8	-2.0	-1.6	-1.2	1.3	-2.1	1.1	1.5	0.6	1.2
Arm fat-free mass (left)	0.4	2.2	4.2	1.0	-2.0	-1.6	-1.3	1.5	-2.1	1.2	1.7	0.8	1.3
Cholesterol lowering medication	0.4	0.5	4.0	0.7	-0.4	0.5	-0.1	-0.1	-0.6	-0.0	0.3	2.0	-0.0
Alcohol drinker status: Previous	0.4	0.5	1.3	0.5	-0.2	-0.7	1.1	0.8	0.1	0.8	0.8	-0.4	0.9
HDL Cholesterol	0.3	0.5	1.4	-0.8	-0.2	-0.1	0.0	-0.6	-0.5	-0.8	-0.8	-1.2	-0.7
Height	0.3	5.3	21.3	3.1	-1.1	0.6	-1.8	-1.2	-3.6	-1.2	-0.1	4.6	-1.1
Medication for hormone replacement therapy	0.3	0.3	1.4	-1.2	-0.5	-0.7	0.6	-0.3	-0.1	-0.4	-0.3	-0.4	-0.3
Fed-up feelings	0.3	0.6	1.2	0.9	0.9	0.7	1.0	-0.2	1.1	-0.1	-0.5	-1.1	-0.2
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	1.8	-0.4	-0.7	-1.3	-0.2	-0.4	-0.5	-0.5	-0.2	0.4	-0.4
Medication: Simvastatin	0.3	0.5	2.7	0.6	0.3	0.5	1.6	0.1	0.3	0.2	0.2	0.9	0.3
Alcohol intake versus 10 years previously	0.3	0.4	0.9	0.8	-0.2	-0.6	0.1	0.9	-0.1	0.9	0.9	-0.2	0.9
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.6	-0.6	0.4	0.1	0.1	-0.7	0.7	-0.8	-0.7	-0.4	-0.7
Standing height	0.3	2.6	5.3	0.7	1.2	2.2	-1.4	-1.8	-0.9	-1.7	-1.4	2.3	-1.8
Ever highly irritable/argumentative for 2 days	0.3	0.4	0.8	0.4	-0.6	-0.9	0.8	0.6	-0.7	0.3	0.7	0.7	0.5
Medication: Omeprazole	0.3	0.3	1.6	0.5	-0.2	0.2	-0.3	0.5	0.2	0.5	0.7	1.3	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.9	-0.5	0.8	0.0	1.4	-0.2	0.7	-0.1	-0.4	-0.4	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	1.4	0.1	-0.2	-0.8	1.2	-0.3	-1.1	0.0	-0.1	0.5	-0.2
Diabetes diagnosed by doctor	0.3	0.4	2.2	0.0	0.8	1.1	-0.1	-0.2	0.4	-0.1	0.0	1.5	-0.1
High cholesterol (Self-reported)	0.3	0.5	1.4	-0.6	1.2	1.0	0.9	0.1	1.2	0.4	-0.0	-0.0	0.2
Ever had prostate specific antigen (PSA) test	0.3	0.4	2.6	0.4	0.3	-0.1	1.6	0.3	0.5	0.7	0.2	-0.0	0.4
Myopia	0.3	0.5	1.5	-0.3	1.0	1.2	-0.2	-0.5	0.8	-0.3	-0.7	-0.5	-0.5
Waist Hip Ratio (WHR)	0.2	1.1	2.5	-0.2	1.4	1.6	1.0	-0.7	1.4	-0.7	-0.6	1.3	-0.7
Average weekly spirits intake	0.2	0.3	0.8	-0.7	0.6	0.9	-0.6	-0.2	0.7	-0.3	-0.4	-0.1	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	2.3	-0.9	-0.3	0.0	-1.5	-0.5	-0.2	-0.4	-0.6	-0.6	-0.5
Pain all over the body in last month	0.2	0.2	0.7	0.2	-0.8	-0.4	-0.7	-0.3	-0.4	-0.3	-0.2	0.2	-0.2
Diabetes (self-reported)	0.2	0.4	0.7	0.4	0.7	0.8	-0.1	0.5	0.7	0.5	0.5	0.9	0.5
Trunk fat-free mass	0.2	1.3	3.1	0.8	-1.4	-1.1	-1.1	1.1	-1.8	1.0	1.3	0.7	1.0
Falls in the last year	0.2	0.3	0.9	0.3	0.6	0.6	-0.9	0.2	0.9	0.2	0.0	-0.4	0.2
Trunk predicted mass	0.2	1.2	2.8	0.9	-1.3	-1.0	-0.9	1.1	-1.7	1.0	1.3	0.7	1.0
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	0.8	0.6	-0.1	0.3	-0.9	-0.2	-0.8	-0.2	-0.1	0.4	-0.2
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.2	-0.4	-1.0	-1.1	0.1	0.2	-0.4	0.0	0.1	-0.7	0.2
High blood pressure (siblings)	0.2	0.3	1.5	0.9	0.3	-0.2	1.2	0.0	0.4	0.3	0.1	0.2	0.1
Health satisfaction	0.2	0.2	1.0	-1.0	-0.1	-0.3	-0.2	0.4	0.5	0.3	0.2	-0.7	0.3
Eye problems/disorders: None of the above	0.2	0.2	1.0	-0.5	0.4	-0.1	-0.4	-0.5	0.2	-0.2	-0.6	-1.0	-0.4
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.5	0.4	-0.3	-0.6	-0.1	0.5	-0.3	0.4	0.4	-0.7	0.4
Family relationship satisfaction	0.2	0.2	0.6	-0.8	0.4	0.1	-0.1	-0.5	0.5	-0.8	-0.6	-0.2	-0.5
Illnesses of siblings: Diabetes	0.2	0.3	0.7	0.7	-0.9	-0.5	0.8	0.3	-0.5	0.4	0.4	0.5	0.3
Breast cancer (self-reported)	0.2	0.3	0.6	-0.2	0.7	0.8	-0.4	-0.3	0.5	-0.5	-0.5	-0.1	-0.5
Arm fat mass (left)	0.2	0.8	1.8	0.3	-1.4	-1.3	-0.3	1.1	-0.5	0.8	1.2	0.3	1.0
Illnesses of father: High blood pressure	0.2	0.3	0.6	0.6	0.4	0.6	0.2	0.3	0.7	0.5	0.4	0.8	0.3
Number of operations (self-reported)	0.2	0.4	1.6	-0.2	0.6	-0.1	1.0	-0.3	1.3	-0.3	-0.1	0.5	-0.2
Heel T-Score	0.1	0.8	1.7	1.0	0.2	0.1	0.4	1.0	-0.1	1.2	1.2	1.3	1.1
Diabetes (mother)	0.1	0.1	0.3	-0.2	0.3	0.2	0.5	-0.3	0.4	-0.2	-0.3	-0.2	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.3	-0.5	-0.1	0.2	-0.6	-0.4	0.4	-0.1	-0.6	-0.6	-0.4
Weight	0.1	0.7	2.0	-0.0	-1.4	-1.1	-1.1	0.6	-1.1	0.3	0.7	0.4	0.5
Hip circumference	0.1	0.5	1.4	-0.6	0.3	0.4	-0.4	-1.0	0.2	-1.2	-0.9	0.4	-1.0
Noisy workplace	0.1	0.1	0.6	-0.5	-0.1	0.3	0.1	0.1	0.8	0.2	0.0	-0.3	0.1
Medication: Lansoprazole	0.1	0.1	0.3	0.2	0.2	0.2	0.2	-0.4	0.1	-0.3	-0.2	0.5	-0.3
Arm fat mass (right)	0.1	0.6	1.5	-0.2	-1.2	-1.2	-0.6	0.8	-0.5	0.5	0.9	0.2	0.7
Birth weight	0.1	0.2	0.6	-0.2	0.8	0.6	-0.5	-0.5	-0.1	-0.4	-0.5	0.1	-0.6
Leg fat percentage (right)	0.1	0.5	2.4	-0.4	0.6	0.6	0.5	-0.5	1.5	-0.6	-0.4	0.5	-0.5
Number of full brothers	0.1	0.2	0.4	0.2	0.5	0.3	0.3	-0.6	0.2	-0.5	-0.6	-0.1	-0.5
Whole body fat mass	0.1	0.3	0.7	0.1	-0.8	-0.7	-0.4	0.5	-0.1	0.3	0.7	0.6	0.4
Medication: Bendroflumethiazide	0.1	0.2	1.0	-0.2	-0.7	-0.5	-1.0	-0.1	-0.0	-0.2	-0.1	-0.4	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.5	0.1	0.3	0.6	-0.2	0.1	0.7	0.1	0.2	0.7	0.1
Hair Pigment	0.0	1.3	3.0	-0.3	0.4	1.1	-0.5	-1.5	-0.3	-1.7	-1.1	1.6	-1.5
Trunk fat percentage	0.0	0.1	0.3	-0.3	-0.3	-0.2	-0.4	-0.1	0.5	-0.3	0.0	0.5	-0.2
Trunk fat mass	0.0	0.2	0.6	0.1	-0.7	-0.4	-0.6	0.3	-0.1	0.0	0.4	0.8	0.2
Waist circumference	0.0	0.1	0.4	-0.1	-0.1	-0.2	-0.2	0.3	0.6	0.0	0.2	0.2	0.2
Arm fat percentage (right)	0.0	0.1	0.3	-0.3	-0.2	-0.4	-0.1	0.1	0.6	-0.1	0.1	0.1	0.1
Body fat percentage	0.0	0.1	0.8	-0.4	-0.1	-0.0	-0.1	-0.2	0.9	-0.4	-0.1	0.4	-0.2
Leg fat mass (right)	0.0	0.1	0.3	0.1	-0.4	-0.2	0.0	0.4	0.3	0.2	0.5	0.5	0.3
Arm fat percentage (left)	0.0	0.1	0.4	-0.2	-0.6	-0.6	0.1	0.4	0.5	0.2	0.4	0.1	0.3
Leg fat percentage (left)	0.0	0.2	0.6	-0.4	0.0	0.1	0.1	-0.3	0.8	-0.5	-0.2	0.6	-0.3
Leg fat mass (left)	0.0	0.1	0.4	0.1	-0.6	-0.4	-0.1	0.4	-0.1	0.1	0.5	0.6	0.3

Hub : Genes

RPS6KB1

Models

Trait associations