TWAS hub - SH3GL1P3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.077	0.027	2.5e-04	0.060	NA	0.035	NA	0.041	1.2e-05	NA	6.7e-04	NA	2.5e-04
2	GTEx	Cells Transformed fibroblasts	0.263	0.053	1.1e-16	0.308	NA	0.303	NA	0.308	1.5e-23	NA	4.4e-23	NA	1.5e-23
3	GTEx	Thyroid	0.081	0.041	7.9e-03	0.001	NA	-0.001	NA	0.001	2.6e-01	NA	3.7e-01	NA	2.8e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Trunk fat percentage	17.3	69.2	92.5	8.6	9.6	6.5
Trunk fat mass	16.6	71.3	97.9	8.8	9.9	6.3
Body fat percentage	16.0	63.3	84.5	8.2	9.2	6.2
Blood Eosinophil Count	15.7	120.6	161.3	11.6	12.7	8.1
Whole body fat mass	15.0	62.8	85.8	8.3	9.3	5.8
Waist circumference	14.4	52.9	67.8	7.6	8.2	5.7
Overall health rating	13.0	27.9	32.1	5.7	5.6	4.4
Leg fat mass (left)	12.7	49.5	67.5	7.4	8.2	5.1
Leg fat mass (right)	12.5	48.4	64.9	7.2	8.1	5.3
Arm fat percentage (left)	12.5	49.9	65.9	7.3	8.1	5.5
Leg fat percentage (right)	11.9	43.2	55.7	6.6	7.5	5.5
Arm fat mass (left)	11.9	48.8	65.8	7.3	8.1	5.3
Arm fat percentage (right)	11.8	46.7	60.1	7.1	7.7	5.5
Arm fat mass (right)	11.8	48.6	64.6	7.2	8.0	5.4
Leg fat percentage (left)	11.8	42.6	55.9	6.7	7.5	5.2
Number of treatments/medications taken	11.3	20.3	26.8	4.5	5.2	3.6
Loneliness, isolation	11.3	15.6	20.2	4.5	4.3	2.9
Health satisfaction	10.8	14.0	14.3	3.6	3.8	3.8
Type 2 Diabetes (T2D) (2012)	10.2	11.8	18.6	2.6	3.2	4.3
Taking other prescription medications	10.0	15.5	20.6	4.0	4.5	3.1
Lung FEV1/FVC ratio	9.6	48.9	67.2	6.8	8.2	5.8
Weight	9.5	46.5	66.6	7.2	8.2	4.6
Smoking status: Current	9.5	15.1	19.1	4.0	4.4	3.2
Alcohol drinker status: Previous	9.2	10.4	14.4	2.8	3.0	3.8
Current tobacco smoking	8.9	14.6	18.2	4.1	4.3	3.0
Fractured/broken bones in last 5 years	8.8	11.3	14.9	2.8	3.9	3.3
Long-standing illness, disability or infirmity	8.5	12.9	17.9	4.2	3.9	2.5
Medication: Gliclazide	8.5	9.6	12.2	3.1	3.5	2.7
Frequency of unenthusiasm / disinterest in last 2 weeks	8.2	10.9	13.0	3.6	3.2	3.0
Wheeze or whistling in the chest in last year	8.1	14.5	22.8	4.8	4.4	1.3
Multivitamins +/- minerals	8.0	10.1	10.9	3.3	3.0	3.2
Ever depressed for a whole week	7.8	9.7	13.3	3.6	3.5	1.9
Triglycerides	7.7	12.7	15.8	3.7	4.0	2.9
Neck or shoulder pain in last month	7.7	11.0	13.4	2.7	3.5	3.7
Ever used hormone-replacement therapy (HRT)	7.5	9.5	15.1	2.8	3.9	2.4
Pain experienced in last month	7.5	12.5	19.4	-3.3	-4.4	-2.7
Medication: Metformin	7.2	10.2	12.9	3.2	3.6	2.7
Serious illness, injury or assault to yourself	7.1	8.6	15.4	2.0	2.6	3.9
Hip circumference	7.0	30.1	42.1	5.3	6.5	4.5
Age at last live birth	7.0	10.2	14.0	-3.2	-3.7	-2.6
BMI	6.9	39.8	52.3	6.8	7.2	4.6
Body mass index (BMI)	6.9	29.4	38.4	5.5	6.2	4.4
Frequency of tiredness / lethargy in last 2 weeks	6.8	11.1	14.6	3.8	3.3	2.8
Myopia	6.8	9.8	15.8	-3.3	-4.0	-1.7
Type 2 Diabetes (T2D) (2018)	6.7	12.5	13.0	3.6	3.6	3.4
Medication for pain relief, constipation, heartburn	6.5	11.1	14.0	-3.1	-3.7	-3.1
Financial situation satisfaction	6.5	8.0	9.6	3.1	2.9	2.5
Medication: Atorvastatin	6.5	8.0	8.7	2.7	3.0	2.9
Fed-up feelings	6.4	11.7	13.7	3.7	3.5	3.1
Family relationship satisfaction	6.4	7.9	11.7	3.0	3.4	1.6
Prospective memory result	6.3	7.7	12.5	3.1	3.5	1.1
Medication: Omeprazole (e.g. Zanprol)	6.3	7.7	9.5	2.6	3.1	2.6
Townsend deprivation index at recruitment	6.2	8.8	11.8	3.4	3.2	2.0
Diabetes diagnosed by doctor	6.2	10.2	10.9	3.2	3.3	3.1
Vitamin and mineral supplements	6.0	8.1	9.0	-3.0	-2.7	-2.8
Medication: Omeprazole	5.9	7.0	8.3	2.3	2.9	2.7
Number of self-reported non-cancer illnesses	5.9	10.2	12.6	3.4	3.5	2.5
Medication for hormone replacement therapy	5.7	6.3	8.0	2.4	2.8	2.3
Frequency of tenseness / restlessness in last 2 weeks	5.3	8.3	11.0	3.3	3.0	2.2
Depression (Nagel 2018)	5.2	7.8	10.5	3.2	2.8	2.2
Age at first live birth	5.2	9.2	11.8	-2.9	-3.4	-2.7
Shortness of breath walking on level ground	5.2	6.2	6.8	2.3	2.6	2.5
Age at First Birth	5.0	7.2	9.3	-3.0	-3.0	-1.9
Hand grip strength (right)	4.7	12.9	17.0	-4.1	-4.1	-2.2
Ulcerative Colitis (UC)	4.6	8.7	12.6	-3.6	-3.5	-1.1
Neuroticism	4.5	10.9	14.1	3.8	3.6	2.4
Diabetes (self-reported)	4.5	6.9	8.2	2.8	2.9	2.2
Exposure to tobacco smoke outside home	4.5	6.0	8.0	2.7	2.8	1.6
Eye problems/disorders: None of the above	4.5	5.2	9.3	-1.0	-2.3	-3.0
Alcohol usually taken with meals	4.4	7.1	9.9	-3.1	-2.8	-1.8
Hand grip strength (left)	4.2	11.1	14.9	-3.8	-3.9	-2.1
Eye problems/disorders: Diabetes related eye disease	4.2	4.6	7.0	1.8	1.9	2.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	4.2	5.0	7.3	2.7	2.7	0.7
Headache pain in last month	4.1	7.1	8.7	2.5	2.9	2.5
Depressed Affect (Nagel 2018)	4.0	8.4	11.5	3.4	3.1	2.0
Sensitivity / hurt feelings	4.0	6.8	8.3	2.2	2.7	2.9
Cholesterol lowering medication	4.0	6.0	8.0	2.1	2.8	2.3
Falls in the last year	3.9	5.3	7.0	1.9	2.6	2.3
High blood pressure (siblings)	3.9	5.6	7.4	2.0	2.7	2.3
Medication for cholesterol	3.9	5.9	7.0	-1.9	-2.6	-2.6
Unable to work because of sickness or disability	3.9	5.0	6.4	2.1	2.1	2.5
Medication: Paracetamol	3.8	5.9	7.6	2.0	2.5	2.8
Risk taking	3.8	5.6	7.0	1.9	2.6	2.5
LDL Cholesterol	3.7	5.8	8.1	2.4	2.8	1.9
Illnesses of siblings	3.7	5.3	9.2	-1.2	-2.3	-3.0
Happiness	3.7	4.5	6.7	2.6	2.3	1.1
Illnesses of father: High blood pressure	3.7	4.6	6.6	-1.9	-2.6	-1.9
Ever unenthusiastic/disinterested for a whole week	3.6	4.4	6.6	2.6	2.4	0.8
Alzheimer’s Disease (including proxy)	3.4	4.9	5.7	-2.4	-2.2	-2.0
Pulse rate	3.4	5.8	6.9	2.0	2.5	2.6
Medication: Seretide 50 evohaler	3.4	3.9	5.6	2.2	2.4	1.1
Body Mass Index (BMI) (2010)	3.3	4.6	6.4	1.9	2.5	1.9
Systolic Blood Pressure	3.3	16.5	23.2	-4.6	-4.8	-2.3
Leg pain on walking	3.3	4.1	6.5	1.6	2.5	1.8
Basal metabolic rate	3.3	18.4	28.5	4.6	5.3	2.3
Pack years of smoking	3.3	4.8	8.5	1.5	2.0	2.9
Pulse rate, automated reading	3.2	10.3	10.8	3.1	3.2	3.3
Leg fat-free mass (left)	3.1	16.3	25.0	4.4	5.0	2.1
Leg predicted mass (left)	3.1	16.2	24.7	4.4	5.0	2.1
Comparative height size at age 10	3.1	16.9	22.9	4.6	4.8	2.5
Irritability	3.1	5.3	7.2	2.7	2.3	1.8
Number of incorrect matches in round	3.0	5.0	7.3	2.7	2.4	1.4
Serious illness, injury or assault of a close relative in last 2 years	3.0	3.4	5.2	-2.3	-2.2	-0.5
Breastfed as a baby	3.0	3.7	5.8	-2.4	-2.0	1.1
Pain type(s) experienced in last month: Hip pain	3.0	3.8	7.7	0.8	1.7	2.8
Arm fat-free mass (left)	3.0	15.3	23.4	4.2	4.8	2.2
Other serious medical condition/disability diagnosed by doctor	2.9	3.7	6.7	1.2	1.7	2.6
Knee pain experienced in last month	2.9	4.5	6.3	2.0	2.5	1.8
Heart disease (siblings)	2.9	3.5	4.8	1.1	2.1	2.2
Neuroticism (Nagel 2018)	2.8	6.7	8.0	2.8	2.7	2.2
Alzheimer’s Disease (in mother)	2.8	3.3	3.4	-1.8	-1.8	-1.8
Reaction Time	2.8	5.3	7.9	2.8	2.8	0.7
Lung FVC	2.8	14.1	17.3	-4.1	-4.2	-2.9
Had menopause	2.8	3.5	4.7	2.2	2.0	1.4
Medication: Allopurinol	2.8	3.8	5.4	2.2	2.3	1.1
High cholesterol (Self-reported)	2.8	4.9	5.9	1.7	2.4	2.4
Major Depression (MDD)	2.7	3.2	4.9	2.2	2.2	0.2
Hayfever, allergic rhinitis or eczema	2.7	5.8	6.1	2.5	2.5	2.3
Hayfever/allergic rhinitis (self-reported)	2.7	3.6	5.1	2.1	2.3	1.1
Neuroticism score	2.7	5.7	6.9	2.6	2.3	2.2
Mean time to correctly identify matches	2.7	5.2	7.7	2.3	2.8	1.6
Guilty feelings	2.7	4.1	6.2	2.5	2.3	0.9
Arm predicted mass (left)	2.7	13.8	21.1	4.1	4.6	1.9
Schizophrenia vs Biploar Disorder	2.6	3.4	5.0	1.7	1.5	2.2
Arm predicted mass (right)	2.6	13.4	21.4	4.1	4.6	1.4
Mood swings	2.6	4.6	6.6	1.7	2.1	2.6
Alcohol drinker status: Never	2.6	3.1	4.1	1.6	1.6	2.0
Waist Hip Ratio (WHR)	2.5	11.3	16.6	4.1	3.2	2.7
Frequency of depressed mood in last 2 weeks	2.5	3.5	5.8	2.4	1.8	1.3
Medication: Ventolin 100micrograms inhaler	2.5	3.2	3.9	2.0	1.6	1.8
Pack years adult smoking proportion	2.4	3.7	7.6	1.1	1.5	2.8
Bilateral oophorectomy (both ovaries removed)	2.4	2.8	4.6	1.9	2.1	0.4
Exposure to tobacco smoke at home	2.4	2.7	4.8	2.2	1.8	-0.2
Eye problems/disorders: Glaucoma	2.4	2.8	3.5	1.2	1.9	1.9
Hearing difficulty/problems: Yes	2.3	3.5	5.2	-1.7	-2.3	-1.6
Maternal smoking around birth	2.3	3.3	5.7	2.4	2.1	0.1
High blood pressure (mother)	2.3	3.2	6.6	-2.6	-1.7	0.1
Arm fat-free mass (right)	2.3	11.9	19.3	3.8	4.4	1.4
Leg fat-free mass (right)	2.3	12.3	19.5	3.9	4.4	1.6
Leg predicted mass (right)	2.3	12.2	19.3	3.9	4.4	1.5
Hearing aid user	2.3	2.6	3.8	-1.8	-2.0	-0.9
Allergy or Eczema	2.2	5.9	6.2	2.3	2.5	2.5
Ever highly irritable/argumentative for 2 days	2.2	2.7	3.3	1.8	1.6	1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	2.2	2.8	3.3	1.8	1.6	1.6
Friendships satisfaction	2.2	2.7	4.0	2.0	1.6	1.2
Back pain experienced in last month	2.2	3.2	5.3	1.6	2.3	1.4
Number of operations (self-reported)	2.2	3.2	3.6	1.9	1.9	1.6
Medication: Co-codamol	2.1	2.4	3.1	1.5	1.7	1.4
Average weekly fortified wine intake	2.1	2.5	3.3	-1.2	-1.7	-1.8
Father’s age at death	2.1	2.8	4.7	-2.2	-1.3	1.4
Glaucoma (self-reported)	2.1	2.5	4.2	0.7	1.7	2.0
Gout (self-reported)	2.0	2.8	4.2	1.4	2.0	1.5
Whole body fat-free mass	2.0	11.3	18.2	3.7	4.3	1.4
Ever had stillbirth, spontaneous miscarriage or termination	2.0	2.2	4.1	1.5	2.0	0.5
Whole body water mass	2.0	11.4	18.4	3.7	4.3	1.4
Commuting to job workplace: Cycle	2.0	2.4	3.3	1.8	1.7	0.9
Qualifications: A levels/AS levels or equivalent	1.9	4.3	8.9	-2.0	-3.0	-0.5
Comparative body size at age 10	1.9	5.4	9.3	3.0	2.2	1.5
Number of children fathered	1.9	2.2	2.6	-1.4	-1.6	-1.5
Coronary Artery Disease (CAD)	1.8	2.1	3.6	1.6	1.9	0.0
Height	1.8	35.3	58.5	6.3	7.7	2.9
Allergy	1.8	4.0	5.3	-2.3	-2.1	-1.6
Medication: Simvastatin	1.8	2.6	3.6	1.4	1.9	1.5
Loud music exposure frequency	1.8	2.0	3.3	1.0	1.8	1.3
Qualifications: O levels/GCSEs or equivalent	1.8	2.9	4.8	-2.2	-2.0	0.1
Irritable Bowel Disease (IBD)	1.7	4.0	6.4	-2.5	-2.3	-0.3
Heel T-Score	1.7	13.6	16.8	-3.4	-4.1	-3.5
Angina	1.7	2.2	3.0	1.3	1.7	1.3
Had other major operations	1.7	2.1	3.3	1.7	1.8	0.4
Pulse wave Arterial Stiffness index	1.7	2.0	3.2	0.9	1.4	1.8
Medication: Paracetamol	1.7	2.9	3.6	1.4	1.8	1.9
Angina (self-reported)	1.7	2.3	3.2	1.3	1.8	1.4
HDL Cholesterol	1.6	2.6	3.1	-1.4	-1.8	-1.7
Qualifications: CSEs or equivalent	1.6	2.1	3.7	-1.4	-1.9	-0.7
Birth weight	1.6	3.4	6.0	2.0	2.5	0.6
Worry too long after embarrassment	1.6	2.7	3.5	1.5	1.5	1.9
Pulse wave peak to peak time	1.6	1.9	3.5	-0.8	-1.2	-1.9
Smoking Status	1.5	3.5	5.5	2.4	2.2	0.3
Relative age of first facial hair	1.5	3.0	4.2	-2.1	-1.8	-1.3
Stomach or abdominal pain in last month	1.5	1.8	5.4	0.1	0.4	2.3
Medication: Cholesterol lowering	1.5	2.4	3.1	1.4	1.8	1.4
Standing height	1.5	15.3	26.0	4.3	5.1	1.0
Blood clot in the leg (DVT)	1.5	1.9	4.3	0.7	1.1	2.1
Osteoarthritis (self-reported)	1.5	1.9	3.1	1.6	1.8	0.5
Chronic bronchitis/emphysema (father)	1.4	1.6	2.6	1.2	0.8	1.6
Illnesses of mother	1.4	1.7	3.2	1.8	1.4	0.1
Length of working week for main job	1.4	1.5	2.6	1.6	1.4	-0.0
Deep venous thrombosis (DVT) (self-reported)	1.4	1.7	4.3	0.5	0.8	2.1
Pulse wave reflection index	1.3	1.6	2.2	-0.9	-1.5	-1.3
Mouth/teeth dental problems: Loose teeth	1.3	1.6	1.8	1.2	1.4	1.2
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.6	2.4	-1.6	-1.0	-1.2
Medication: Ramipril	1.2	1.5	4.1	-0.6	0.2	2.0
Trunk fat-free mass	1.2	6.8	11.4	2.9	3.4	0.8
Medication for cholesterol, blood pressure or diabetes	1.2	2.1	2.9	-1.4	-1.7	-1.2
HbA1C	1.1	1.2	2.3	0.6	1.5	1.0
Rheumatoid Arthritis	1.1	1.5	3.6	-0.5	-0.9	-1.9
Chronotype (morning person)	1.1	2.6	4.6	0.5	1.7	2.1
Forced vital capacity (FVC)	1.1	4.1	7.6	-1.5	-1.6	-2.8
Trunk predicted mass	1.1	6.5	10.9	2.8	3.3	0.8
Forced vital capacity (FVC), Best measure	1.1	4.0	7.9	-1.2	-1.6	-2.8
Suffer from ‘nerves’	1.1	1.8	2.8	1.7	1.4	0.7
Chest pain or discomfort	1.1	1.6	2.4	1.6	1.3	0.8
Smoking status: Previous	1.1	1.7	2.4	-1.0	-1.3	-1.6
Neuroticism (2016)	1.0	1.4	2.0	0.9	1.1	1.4
Financial difficulties in last 2 years	1.0	1.3	3.1	1.8	0.8	0.6
Medication: Ibuprofen	1.0	1.2	2.4	0.6	0.9	1.5
Medication: Aspirin	1.0	1.4	1.8	0.8	1.3	1.3
Illnesses of siblings: Diabetes	1.0	1.3	1.8	0.8	1.2	1.3
Asthma (self-reported)	1.0	2.0	3.5	1.9	1.6	0.0
Tinnitus: Yes, now most or all of the time	1.0	1.2	2.1	0.9	1.4	0.8
Medication: Bendroflumethiazide	1.0	1.5	2.1	1.0	1.2	1.5
Alzheimer’s Disease (in father)	0.9	1.0	1.5	-0.8	-0.9	-1.2
Average weekly spirits intake	0.9	1.1	1.5	0.9	1.2	1.0
Age when periods started (menarche)	0.9	2.2	3.7	-1.9	-1.3	-1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.0	2.8	-1.3	-1.2	-1.7
Alcohol intake versus 10 years previously	0.9	1.4	1.6	1.1	1.3	1.2
Asthma	0.9	1.8	3.3	1.8	1.4	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	2.2	1.5	0.9	-0.5
Handedness (chirality/laterality): Left-handed	0.9	1.0	2.7	-0.2	-0.6	-1.6
Osteoporosis (self-reported)	0.9	1.1	1.5	1.0	1.2	1.0
Ulcerative Colitis	0.8	1.2	1.6	-1.2	-0.8	1.2
Blood Platelet Count	0.8	9.5	20.2	-4.5	-2.9	-0.1
Systolic blood pressure, automated reading	0.8	2.4	3.6	-1.4	-1.9	-1.3
Diabetes (mother)	0.8	1.0	2.0	0.6	0.9	1.4
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.7	3.0	-1.0	-1.1	-1.7
Lung cancer (father)	0.8	0.9	1.4	1.2	0.9	0.7
Tense / ‘highly strung’	0.8	1.2	1.7	1.3	0.8	1.2
Medication: Amlodipine	0.8	1.1	1.8	-1.3	-1.2	-0.2
Emphysema/chronic bronchitis	0.8	0.9	2.4	0.3	0.2	1.6
Had major operations	0.8	1.0	1.5	1.2	0.8	0.8
Qualifications: nursing, teaching	0.8	1.2	2.2	-1.5	-1.1	0.5
Medication: Aspirin	0.8	1.1	1.5	0.7	1.2	1.2
Miserableness	0.8	1.5	2.1	1.4	1.3	0.8
Supplements: Calcium	0.8	0.9	1.6	1.3	1.0	-0.3
Mean Putamen Volume	0.7	0.8	1.5	-1.2	-0.9	0.2
Hypothyroidism (self reported)	0.7	1.6	3.0	1.7	1.4	0.2
Supplements: Glucosamine	0.7	0.9	1.4	-1.1	-0.4	-1.2
Qualifications: None of the above	0.7	1.5	3.0	1.1	1.7	0.4
Heart attack	0.7	0.9	1.6	1.2	0.9	0.6
Hair/balding pattern: Pattern 3	0.7	1.0	2.3	-0.8	-1.5	-0.0
Mouth/teeth dental problems: Dentures	0.7	1.2	2.4	0.4	1.0	1.6
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	1.2	0.7	1.1	1.0
Depression (self-reported)	0.7	0.8	1.4	1.1	0.1	-1.2
Illnesses of father: Heart disease	0.7	1.0	1.8	1.4	1.0	-0.4
Ever had bowel cancer screening	0.7	0.9	1.6	0.9	0.4	1.3
Prostate Cancer	0.6	0.9	1.7	-1.3	-0.7	0.7
Respiratory disease	0.6	1.4	2.1	1.5	1.4	-0.1
Ever had hysterectomy (womb removed)	0.6	0.6	1.4	0.7	1.2	-0.1
Sitting height	0.6	4.1	6.0	2.3	2.4	-1.1
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	2.2	1.5	1.0	0.1
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.3	1.1	0.7	0.5
Qualifications: College or University degree	0.6	1.9	3.9	0.4	-1.3	-2.0
Alcohol intake frequency.	0.6	1.3	3.2	0.5	0.7	1.8
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	3.3	0.7	0.1	-1.8
Mother’s age at death	0.6	0.7	1.2	-1.1	-1.0	-0.4
Heart attack/myocardial infarction (self-reported)	0.6	0.8	1.3	1.1	0.8	0.7
Ovarian Cancer	0.5	0.6	1.0	0.4	0.9	1.0
Lupus	0.5	0.7	1.4	-0.8	-1.2	-0.4
Schizophrenia (2014)	0.5	1.1	2.8	0.8	0.2	1.7
Blood White Count	0.5	3.7	5.8	1.4	2.4	1.8
Hearing difficulty/problems with background noise	0.5	0.7	1.2	-0.5	-0.9	-1.1
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	1.7	0.6	0.1	-1.3
Commuting to job workplace: Walk	0.5	0.6	0.8	-0.6	-0.8	-0.9
Average weekly champagne plus white wine intake	0.5	0.6	1.1	0.8	1.1	0.4
Supplements: Fish oil (including cod liver oil)	0.5	0.6	0.7	-0.8	-0.8	0.7
Cardiovascular Disease	0.4	1.4	3.1	0.3	1.0	1.8
Hair Pigment	0.4	10.9	15.8	3.9	4.0	1.3
Relative age voice broke	0.4	0.7	0.8	-0.9	-0.8	-0.8
Mouth/teeth dental problems	0.4	0.6	0.9	-0.9	-0.9	-0.3
Pain all over the body in last month	0.4	0.4	0.7	0.8	0.6	-0.5
Time employed in main current job	0.4	0.5	0.7	0.9	0.9	0.3
Number of live births	0.4	0.5	0.9	-0.9	-0.9	-0.1
Hair/balding pattern: Pattern 4	0.4	0.9	2.6	-0.4	-0.2	-1.6
Birth weight of first child	0.4	0.8	1.0	-1.0	-0.7	-1.0
Heart disease (mother)	0.4	0.5	0.7	0.8	0.6	0.7
Medication: Lisinopril	0.4	0.5	0.7	-0.9	-0.8	-0.4
Tanning	0.3	3.7	7.6	0.7	1.7	2.8
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	0.9	0.1	-0.3	1.0
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	0.9	-0.9	-0.5	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.8	1.7	-0.7	-0.6	-1.3
Impedance of arm (left)	0.3	1.3	1.6	1.1	1.3	1.0
Peak expiratory flow (PEF)	0.3	0.8	1.6	-1.2	-0.7	-0.5
Number of full brothers	0.3	0.4	0.5	0.6	0.7	0.7
Medication: Blood pressure	0.3	0.5	0.8	0.3	0.7	0.9
Eye problems/disorders: Cataract	0.3	0.3	0.8	-0.1	0.4	0.9
Bipolar Disorder (2018)	0.2	0.3	0.6	-0.8	-0.4	-0.1
Schizophrenia (2018)	0.2	0.5	1.2	1.1	0.3	0.4
Breast Cancer	0.2	0.5	0.6	-0.6	-0.7	-0.7
Fasting Glucose	0.2	0.2	0.3	-0.1	-0.6	-0.5
Supplements: Zinc	0.2	0.2	0.6	0.1	0.3	0.8
Diabetes (father)	0.2	0.3	0.4	-0.5	-0.7	0.2
High blood pressure	0.2	0.6	1.5	-0.1	0.5	1.2
Medication: Atenolol	0.2	0.3	0.4	-0.7	0.0	0.6
Nervous feelings	0.2	0.4	0.8	-0.6	-0.4	-0.9
Hair/balding pattern: Pattern 2	0.2	0.2	0.6	-0.2	0.3	0.7
Medication: Lansoprazole	0.2	0.2	0.5	0.2	0.2	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.6	0.8	0.3	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.5	-0.7	0.1	0.4
Number of full sisters	0.2	0.3	0.3	0.6	0.5	0.5
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.4	-0.7	-0.3	-0.5
Supplements: Vitamin C	0.2	0.3	0.8	0.9	0.2	-0.2
Hypertension (Self-reported)	0.2	0.7	1.6	-0.1	0.7	1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	0.6	0.3	0.3	0.8
Ever taken oral contraceptive pill	0.2	0.2	0.5	0.3	0.7	-0.3
Commuting to job workplace: Public transport	0.2	0.3	0.4	0.6	0.3	0.5
Ever had prostate specific antigen (PSA) test	0.2	0.3	0.6	-0.5	-0.0	0.8
Age started oral contraceptive pill	0.2	0.2	0.5	-0.4	-0.2	-0.7
Vascular/heart problems diagnosed by doctor	0.2	0.6	1.6	0.0	-0.5	-1.3
Basal cell carcinoma (self-reported)	0.2	0.3	0.4	0.6	0.5	-0.4
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.8	-0.4	-0.9	0.3
Worry (Nagel 2018)	0.1	0.2	0.3	-0.3	-0.6	-0.4
Crohns Disease (2012)	0.1	0.2	0.5	-0.7	-0.2	0.4
Primary Biliary Cirrhosis	0.1	0.2	0.3	0.5	0.5	-0.3
Severe depression (siblings)	0.1	0.1	0.4	0.1	-0.1	0.6
Medication: Levothyroxine sodium	0.1	0.2	0.5	0.7	0.2	-0.0
Past tobacco smoking	0.1	0.1	0.2	-0.5	-0.3	0.2
Impedance of arm (right)	0.1	0.6	0.8	0.7	0.7	0.9
Forced expiratory volume in 1-second (FEV1)	0.1	0.5	1.0	-0.6	-0.2	-1.0
Noisy workplace	0.1	0.1	0.1	-0.3	0.4	0.0
Migraine (self-reported)	0.1	0.1	0.3	0.5	0.1	0.1
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.3	0.4	0.3	-0.5
Mineral and other dietary supplements	0.1	0.1	0.2	-0.2	-0.2	-0.5
Illnesses of father: None of the above (group 1)	0.1	0.1	0.3	-0.5	-0.0	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.4	-0.6	-0.4	-0.3
Medication: Blood pressure	0.1	0.1	0.2	0.2	0.5	0.4
Ever smoked	0.1	0.1	0.1	0.4	0.3	0.3
Average weekly beer plus cider intake	0.1	0.2	0.6	-0.2	0.1	0.8
Impedance of whole body	0.1	0.6	0.7	0.8	0.8	0.6
Bipolar Disorder or Schizophrenia	0.0	0.1	0.2	0.4	0.0	0.2
Crohns Disease (2017)	0.0	0.1	0.2	-0.4	-0.2	-0.1
Verbal and Numeric Reasoning (VNR)	0.0	0.1	0.3	-0.0	-0.5	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0
Blood Red Count	0.0	0.5	1.2	0.4	0.2	-1.1
Impedance of leg (right)	0.0	0.1	0.3	-0.0	-0.1	0.5
Impedance of leg (left)	0.0	0.0	0.1	-0.0	-0.1	0.3
Fluid intelligence score	0.0	0.1	0.2	0.1	-0.2	0.4
Worrier / anxious feelings	0.0	0.1	0.1	-0.3	-0.3	0.2
Commuting to job workplace: Car/motor vehicle	0.0	0.0	0.1	-0.1	-0.0	0.3
Average weekly red wine intake	0.0	0.0	0.1	-0.3	0.1	-0.0
Breast cancer (self-reported)	0.0	0.1	0.1	0.2	-0.0	-0.3
Wears glasses or contact lenses	0.0	0.0	0.0	0.1	0.0	0.1
Diastolic blood pressure, automated reading	0.0	0.1	0.2	-0.5	-0.3	-0.2

Hub : Genes

SH3GL1P3

Models

Trait associations