[Hub]/) : Traits : Blood Eosinophil Count : ← →

chr22:36,191,428-38,258,810

Best TWAS P=7.69e-33 · Best GWAS P=5.75e-30 conditioned to 3.66e-17

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum TST 0.22 0.01 lasso 7 0.01 1.5e-01 8.2 -6.4 1.9e-10 0.08 0.09 0.04 TRUE
2 GTEx Breast Mammary Tissue (Female) FOXRED2 0.41 -0.01 enet 32 0.02 6.2e-02 3.2 5.8 6.8e-09 0.03 0.08 0.06 TRUE
3 GTEx Skin Not Sun Exposed Suprapubic IL2RB 0.35 0.32 lasso 2 0.30 1.0e-16 -6.1 6.1 9.8e-10 -0.57 1.00 0.00 FALSE
4 GTEx Skin Sun Exposed Lower leg IL2RB 0.34 0.28 lasso 2 0.28 1.6e-23 -6.1 6.3 3.6e-10 -0.56 1.00 0.00 TRUE
5 NTR Blood PVALB 0.09 0.08 bslmm 674 0.07 6.8e-23 10.8 -10.8 2.4e-27 0.10 0.32 0.68 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma NCF4 0.06 0.05 lasso 3 0.04 1.7e-09 10.8 -11.2 3.9e-29 0.06 0.06 0.94 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NCF4 0.08 0.06 enet 4 0.05 1.4e-06 11.2 -11.9 7.7e-33 0.03 0.00 1.00 TRUE
8 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma NCF4 0.08 0.02 blup 87 0.04 2.2e-03 10.8 -10.3 6.6e-25 -0.03 0.01 0.75 FALSE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SSTR3 0.04 0.00 blup 101 0.02 6.6e-03 -1.8 5.9 3.9e-09 -0.05 0.06 0.04 TRUE
10 The Cancer Genome Atlas Prostate Adenocarcinoma NCF4 0.05 0.02 lasso 4 0.04 1.9e-05 10.8 -10.9 1.4e-27 0.01 0.02 0.94 FALSE
11 The Cancer Genome Atlas Skin Cutaneous Melanoma NCF4 0.32 0.03 blup 86 0.10 1.2e-03 -2.1 -5.3 1.1e-07 -0.03 0.02 0.09 FALSE
12 The Cancer Genome Atlas Testicular Germ Cell Tumors NCF4 0.18 0.03 blup 87 0.02 5.4e-02 -7.8 -7.3 2.5e-13 -0.06 0.02 0.50 FALSE