TWAS hub - MIIP

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0810	0.0280	5.5e-04	0.080	0.025	0.066	0.061	0.071	5.4e-10	4.8e-04	1.6e-08	6.8e-08	5.6e-09
2	GTEx	Thyroid	0.1170	0.0450	8.4e-03	0.031	NA	0.046	NA	0.031	1.8e-03	NA	1.8e-04	NA	2.0e-03
3	GTEx	Whole Blood	0.2170	0.0430	8.1e-12	0.192	NA	0.186	NA	0.191	2.0e-17	NA	5.9e-17	NA	2.5e-17
4	METSIM	Adipose	0.0775	0.0269	5.0e-04	0.000	0.013	0.003	0.013	0.002	2.9e-01	4.3e-03	1.2e-01	3.7e-03	1.7e-01
5	ROSMAP	Brain Pre-frontal Cortex	0.1013	0.0326	2.4e-04	0.072	0.032	0.090	0.078	0.078	1.5e-09	5.3e-05	1.2e-11	3.0e-10	3.1e-10
6	TCGA	Bladder Urothelial Carcinoma	0.0660	0.0380	6.3e-03	0.012	0.013	0.015	NA	0.008	2.8e-02	2.8e-02	1.8e-02	NA	6.4e-02
7	TCGA	Breast Invasive Carcinoma	0.0329	0.0153	6.5e-06	0.029	0.020	0.017	NA	0.023	1.2e-06	5.4e-05	1.7e-04	NA	1.1e-05
8	TCGA	Colon Adenocarcinoma	0.0550	0.0330	6.6e-03	0.043	0.033	0.038	NA	0.037	1.7e-03	5.3e-03	2.8e-03	NA	3.2e-03
9	TCGA	Glioblastoma Multiforme	0.1500	0.0780	1.9e-03	0.106	0.078	0.059	NA	0.080	4.0e-04	2.2e-03	7.0e-03	NA	2.0e-03
10	TCGA	Brain Lower Grade Glioma	0.0692	0.0306	1.8e-06	0.071	0.061	0.068	NA	0.068	1.7e-08	2.0e-07	3.6e-08	NA	3.9e-08
11	TCGA	Prostate Adenocarcinoma	0.0946	0.0414	6.5e-07	0.080	0.081	0.084	NA	0.080	1.0e-08	7.4e-09	4.2e-09	NA	9.9e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Blood Eosinophil Count	13.0	100.3	153.8	-11.5	1.3	8.3	-3.3	-11.0	-9.8	-12.2	-8.8	-11.8	-12.4	-12.3
Wears glasses or contact lenses	4.9	5.7	9.9	2.5	1.1	-2.5	0.5	3.1	2.8	2.7	2.4	2.5	2.6	2.1
Angina	4.8	6.3	12.5	-3.0	-2.3	1.0	-3.5	-2.3	-0.6	-2.8	-1.7	-2.9	-2.6	-3.3
Blood Platelet Count	4.7	54.3	222.0	-5.1	-0.0	14.9	0.4	-6.9	-4.0	-8.5	-9.2	-6.4	-7.8	-5.2
High cholesterol (Self-reported)	4.7	8.3	14.2	-2.9	-0.9	3.8	-0.5	-3.1	-2.5	-3.7	-2.8	-3.3	-2.9	-3.2
Hearing difficulty/problems: Yes	4.6	7.0	12.7	3.3	0.9	-2.1	1.5	3.6	2.3	3.1	1.6	3.2	2.9	3.2
Medication: Ventolin 100micrograms inhaler	4.1	5.3	9.4	-2.8	0.5	1.7	-0.5	-1.6	-2.9	-3.1	-1.3	-3.0	-3.0	-2.7
Angina (self-reported)	4.1	5.4	11.6	-2.7	-2.3	0.9	-3.4	-2.0	-0.3	-2.5	-1.6	-2.6	-2.3	-3.0
Asthma	3.9	7.7	14.7	-3.4	1.0	0.8	-3.0	-2.2	-2.0	-3.5	-1.7	-3.5	-3.8	-3.3
Asthma (self-reported)	3.9	7.7	14.7	-3.4	1.1	0.9	-3.0	-2.3	-2.1	-3.5	-1.7	-3.5	-3.8	-3.3
Alcohol intake versus 10 years previously	3.7	5.5	14.8	-2.1	0.1	3.9	-0.8	-2.8	-2.4	-2.6	-2.3	-2.2	-2.3	-2.3
Osteoarthritis (self-reported)	3.7	4.8	10.7	-3.3	-1.5	0.5	-0.6	-2.3	-0.9	-2.7	-0.3	-3.1	-2.8	-3.0
Medication: Cholesterol lowering	3.5	5.5	9.5	-2.3	-3.1	2.1	-1.6	-2.6	-0.8	-2.8	-2.5	-2.7	-1.9	-2.5
Medication: Seretide 50 evohaler	3.3	3.8	7.1	-2.4	1.5	1.5	-1.1	-1.1	-1.4	-2.7	-2.1	-2.5	-2.6	-1.8
Smoking status: Current	3.3	5.2	9.9	-2.9	-0.6	1.7	-1.9	-1.3	-3.1	-2.7	-0.8	-2.8	-2.4	-2.9
Medication: Lansoprazole	3.2	3.7	5.9	-2.1	-1.6	1.9	-2.1	-2.4	-1.7	-1.9	-0.6	-2.0	-1.9	-2.3
Wheeze or whistling in the chest in last year	3.2	5.8	13.0	-2.7	-0.4	2.5	-1.9	-2.1	-3.6	-2.7	0.3	-2.6	-2.9	-2.5
Family relationship satisfaction	3.2	3.9	9.1	2.4	0.8	-1.0	3.0	2.5	0.7	2.1	0.6	2.3	1.8	2.5
Alcohol drinker status: Previous	3.1	3.5	5.6	2.1	0.6	-1.8	0.1	2.1	1.5	2.4	1.6	2.2	2.3	2.3
Townsend deprivation index at recruitment	2.9	4.1	5.5	-2.1	2.2	2.2	-2.0	-1.6	-1.7	-2.4	-1.5	-2.2	-2.0	-1.9
Current tobacco smoking	2.9	4.8	10.6	-2.8	-0.5	1.8	-1.8	-1.2	-3.2	-2.5	-0.6	-2.7	-2.2	-2.7
Taking other prescription medications	2.9	4.5	7.4	-2.7	-0.4	0.9	-2.7	-1.5	-1.0	-2.6	-1.9	-2.7	-2.3	-2.7
Medication: Simvastatin	2.8	4.0	6.7	-2.2	-1.0	1.6	-0.4	-2.5	-1.4	-2.6	-2.3	-2.4	-2.0	-2.6
Supplements: Calcium	2.8	3.1	4.8	2.1	2.2	-1.6	0.9	2.0	1.6	1.9	1.2	2.0	1.7	1.8
Hearing difficulty/problems with background noise	2.7	4.3	8.4	2.4	-0.7	-1.9	0.8	2.9	2.1	2.4	1.4	2.4	2.1	2.5
Noisy workplace	2.7	3.3	6.1	1.8	-0.5	-2.1	0.8	1.3	1.7	2.2	2.4	1.9	2.5	1.8
Financial difficulties in last 2 years	2.6	3.5	7.8	-2.4	-0.2	1.5	-0.6	-2.8	-1.9	-2.2	-0.5	-2.3	-1.6	-2.3
Respiratory disease	2.5	5.7	12.3	-2.7	1.2	0.5	-3.5	-1.8	-1.8	-2.7	-0.7	-2.8	-3.3	-2.8
Had major operations	2.5	3.0	4.9	1.8	0.3	-1.8	0.5	2.2	0.8	2.2	2.2	2.0	1.9	1.8
Commuting to job workplace: Walk	2.5	2.7	7.9	1.8	-0.2	-1.4	0.4	1.5	2.8	1.8	1.0	1.8	1.8	1.8
Forced expiratory volume in 1-second (FEV1), Best measure	2.4	7.7	14.0	3.7	-0.3	-1.5	2.2	2.5	1.0	3.6	2.4	3.7	3.4	3.4
Birth weight of first child	2.4	4.3	7.6	2.2	0.1	-2.2	0.0	1.0	2.8	2.7	1.9	2.6	2.2	2.7
Bipolar Disorder (2018)	2.3	3.6	8.6	-1.5	-0.5	2.4	0.5	-2.1	-2.1	-2.1	-2.9	-1.8	-1.7	-1.8
Medication: Ramipril	2.3	3.0	8.2	-1.8	-1.6	0.0	-2.9	-1.7	0.1	-1.6	-2.4	-1.9	-1.3	-1.6
Hair/balding pattern: Pattern 2	2.2	2.8	5.3	-2.3	-1.4	0.9	-0.3	-1.6	-1.8	-1.8	-1.1	-2.1	-1.9	-2.2
Serious illness, injury or assault of a close relative in last 2 years	2.2	2.6	4.9	1.7	-1.2	-2.2	1.0	0.0	1.0	2.0	1.8	1.8	2.2	1.3
Mouth/teeth dental problems: Bleeding gums	2.2	2.9	5.3	1.9	-1.2	-1.7	0.3	1.8	2.2	1.8	0.9	1.8	2.3	1.9
Handedness (chirality/laterality): Left-handed	2.2	2.6	7.3	1.3	0.1	-1.4	2.0	2.1	0.6	1.6	2.7	1.4	1.5	1.3
Smoking Status	2.1	5.1	10.4	-2.8	0.6	2.9	-0.4	-0.6	-3.2	-2.8	-0.9	-2.8	-2.3	-2.7
Eye problems/disorders: None of the above	2.1	2.5	3.6	-1.8	-0.4	1.8	-0.1	-1.4	-1.9	-1.7	-1.4	-1.7	-1.9	-1.7
Age at First Birth	2.0	2.9	6.8	-1.5	-1.3	2.6	-1.3	-1.7	-1.0	-2.0	-1.6	-1.8	-1.7	-1.7
Ulcerative Colitis (UC)	1.9	3.5	5.9	-2.3	-1.9	0.6	-1.1	-2.3	0.9	-2.2	-1.8	-2.4	-1.8	-2.2
Illness, injury, bereavement, stress in last 2 years	1.9	2.3	6.4	-1.9	1.3	1.1	-1.2	-0.3	-0.1	-1.8	-1.5	-1.8	-2.5	-1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.9	4.0	7.1	2.5	-0.8	-1.3	2.7	1.9	1.4	2.3	1.4	2.4	2.2	2.3
Tinnitus: Yes, now most or all of the time	1.9	2.2	4.8	1.3	-1.2	-1.7	1.4	1.9	2.2	1.2	0.9	1.1	1.5	1.5
Irritable Bowel Disease (IBD)	1.8	4.4	7.1	-2.5	-0.9	1.3	-1.6	-2.5	1.4	-2.5	-2.6	-2.7	-2.0	-2.1
Supplements: Zinc	1.8	1.9	5.9	1.6	0.3	-0.1	0.5	2.4	-0.2	1.7	1.5	1.8	1.1	1.7
Forced vital capacity (FVC), Best measure	1.8	6.5	12.9	3.6	-0.2	-1.1	1.5	2.4	0.6	3.3	2.4	3.5	3.1	3.2
Friendships satisfaction	1.8	2.2	5.2	1.8	-0.4	-1.0	2.3	1.9	0.8	1.5	0.9	1.6	1.2	1.9
Illnesses of father: High blood pressure	1.8	2.2	8.8	1.6	-3.0	-1.4	-0.4	1.1	1.8	1.1	0.1	1.2	1.7	1.0
Ever depressed for a whole week	1.8	2.2	6.6	0.9	0.5	-2.6	-1.1	1.3	1.4	1.5	1.7	1.2	1.8	1.3
Ulcerative Colitis	1.7	2.5	5.8	-1.4	-2.0	1.0	-2.1	-2.4	0.7	-1.4	-1.4	-1.5	-1.4	-1.2
Average weekly fortified wine intake	1.7	2.0	4.5	-1.7	-0.3	0.8	-0.8	-1.1	-1.5	-1.8	-0.6	-1.8	-2.1	-1.8
Reason for reducing amount of alcohol drunk: Health precaution	1.7	1.9	3.7	1.6	-0.8	-1.7	-0.4	1.2	0.9	1.7	1.9	1.6	1.3	1.3
Eye problems/disorders: Diabetes related eye disease	1.6	1.8	4.3	1.4	-0.8	-1.9	0.3	1.2	2.1	1.3	1.0	1.2	1.4	1.1
Medication: Paracetamol	1.6	2.6	4.2	-1.9	0.3	1.4	-1.1	-1.2	-1.7	-1.9	-1.4	-1.9	-2.0	-2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.9	4.7	-1.4	0.3	1.6	-2.2	-1.2	-0.5	-1.3	-1.7	-1.3	-1.2	-1.4
Fractured/broken bones in last 5 years	1.6	2.1	7.7	-1.3	-0.6	2.8	0.5	-1.6	-1.6	-1.6	-0.7	-1.3	-1.4	-1.1
Alzheimer’s Disease (in father)	1.5	1.6	6.2	0.7	1.9	0.0	2.5	2.2	-1.0	0.7	0.5	0.7	0.4	0.7
Alzheimer’s Disease (including proxy)	1.5	2.1	4.3	1.5	2.1	-0.6	1.8	1.2	-0.2	1.5	2.0	1.6	1.1	1.5
Chronic bronchitis/emphysema (mother)	1.5	1.7	3.7	-1.1	-0.3	1.4	-1.2	-1.9	-0.3	-1.7	-0.8	-1.4	-1.8	-1.3
Heart disease (mother)	1.5	1.8	3.1	-1.6	-1.2	1.2	-0.2	-0.7	-1.1	-1.6	-1.4	-1.5	-1.8	-1.7
Chest pain or discomfort	1.5	2.1	3.3	-1.6	-1.8	0.3	-1.8	-1.3	-1.5	-1.5	0.8	-1.6	-1.3	-1.6
Illnesses of siblings: Diabetes	1.5	1.8	3.9	1.0	-1.9	-1.9	-0.7	0.6	2.0	1.1	1.9	0.9	0.7	1.0
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	3.2	-1.5	-0.8	0.8	0.4	-1.3	-1.5	-1.3	-0.6	-1.5	-1.6	-1.8
Diastolic blood pressure, automated reading	1.5	4.6	11.4	-2.0	-3.4	1.6	0.8	-2.1	-1.6	-2.4	-2.9	-2.3	-1.4	-1.8
Frequency of depressed mood in last 2 weeks	1.4	2.0	7.7	0.6	-2.8	-2.1	-0.8	0.5	1.4	1.1	1.3	0.8	1.4	0.7
Other serious medical condition/disability diagnosed by doctor	1.4	1.9	4.8	0.7	-1.5	-2.2	-1.1	0.3	1.8	1.4	1.4	1.0	1.7	0.5
Maternal smoking around birth	1.4	2.0	4.8	1.1	-0.3	-1.5	-2.2	0.5	2.1	1.3	0.7	1.2	1.3	1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.4	1.9	5.2	0.6	-2.3	-2.1	0.3	0.0	2.1	1.0	1.7	0.7	1.3	0.5
Lung cancer (father)	1.4	1.7	3.5	-0.9	0.3	1.8	-1.6	-1.4	-1.2	-1.4	-1.9	-1.1	-1.0	-0.9
Loud music exposure frequency	1.4	1.6	6.0	-1.4	0.1	0.2	0.0	-0.7	-2.4	-1.2	0.3	-1.3	-1.5	-1.8
Hypothyroidism/myxoedema (self-reported)	1.4	2.6	5.4	-1.6	1.9	1.3	-1.1	-1.8	-0.6	-1.6	-2.0	-1.6	-2.3	-1.3
Health satisfaction	1.4	1.8	9.2	1.0	-0.3	-1.1	0.3	0.9	0.1	1.4	3.0	1.2	1.5	0.9
Qualifications: College or University degree	1.4	4.4	7.7	2.5	0.0	-1.7	0.7	2.8	2.3	2.5	1.2	2.5	2.0	2.7
Medication: Allopurinol	1.4	1.9	4.0	-2.0	0.4	1.2	-0.7	-0.5	-1.0	-1.8	-0.9	-1.8	-1.8	-1.7
Crohns Disease (2017)	1.3	2.9	7.6	-1.8	0.5	1.3	-1.4	-1.8	1.6	-2.0	-2.8	-2.0	-1.6	-1.3
Medication for cholesterol, blood pressure or diabetes	1.3	2.2	8.9	1.1	3.0	-1.3	1.7	1.7	0.6	1.4	0.5	1.3	0.5	1.4
Average weekly red wine intake	1.3	1.9	5.1	1.1	1.3	-1.2	0.9	2.2	0.9	1.3	2.1	1.3	1.0	1.1
Eye problems/disorders: Glaucoma	1.3	1.5	3.0	1.3	-1.2	-1.4	0.1	0.5	1.7	1.1	1.3	1.2	1.5	1.4
Cholesterol lowering medication	1.3	1.8	3.7	-1.5	0.3	1.3	-0.5	-1.1	-1.5	-1.6	-1.2	-1.5	-1.7	-1.9
Depression (Nagel 2018)	1.2	1.8	4.2	0.8	-1.5	-2.0	0.3	0.5	1.9	1.2	2.0	0.9	1.3	0.6
Lupus	1.2	1.9	8.6	-0.8	-0.7	1.8	-0.0	-1.6	-2.9	-1.1	1.0	-0.9	-1.3	-0.8
Primary Biliary Cirrhosis	1.2	1.6	5.1	-0.9	-0.8	2.3	-0.6	-1.9	-1.8	-1.2	-0.7	-1.0	-0.8	-0.9
Time employed in main current job	1.2	1.3	3.8	-1.3	-1.6	-0.6	-1.4	-0.4	0.9	-1.0	-1.9	-1.3	-0.3	-0.7
Gout (self-reported)	1.2	1.7	5.4	-1.1	1.3	2.3	0.1	-0.3	-1.8	-1.4	-1.0	-1.2	-1.4	-0.8
Mood swings	1.2	2.1	5.1	1.5	-0.8	-1.5	-0.6	0.8	0.3	2.0	1.6	1.8	2.3	1.3
Number of self-reported non-cancer illnesses	1.2	2.1	3.1	-1.7	-1.6	0.2	-1.5	-1.8	-1.2	-1.5	-0.8	-1.6	-1.6	-1.7
Ever smoked	1.2	2.1	3.8	-1.9	0.1	2.0	-0.1	-0.9	-1.9	-1.6	0.1	-1.7	-1.5	-1.9
Alcohol usually taken with meals	1.1	1.8	4.8	1.1	-1.1	-1.3	1.6	1.6	-0.4	1.4	2.2	1.2	0.9	1.0
Pulse wave reflection index	1.1	1.4	7.3	-0.3	-1.8	1.7	-0.0	0.2	-0.5	-1.0	-2.7	-0.6	-0.2	-0.1
Illnesses of father: Heart disease	1.1	1.5	6.1	-1.0	-2.0	0.9	-0.8	-1.1	-0.1	-1.2	-2.5	-1.1	-0.4	-0.6
Qualifications: nursing, teaching	1.1	1.7	4.4	1.1	0.5	-1.0	2.1	1.8	0.6	1.4	1.5	1.3	0.8	1.2
Average weekly beer plus cider intake	1.1	1.6	7.2	-0.8	-0.1	2.7	-0.3	-1.7	-1.4	-1.3	-0.7	-1.0	-1.1	-1.0
Alzheimer’s Disease (in mother)	1.0	1.2	5.0	1.0	-0.1	-1.2	-0.4	-0.7	1.1	1.2	2.2	1.1	0.8	0.7
Major Depression (MDD)	1.0	1.2	3.5	0.9	0.0	-1.9	0.1	1.2	0.5	1.3	1.5	1.0	1.3	0.9
Breast Cancer	1.0	2.4	6.0	-1.3	-0.5	1.7	1.5	-0.9	-2.4	-1.5	-1.9	-1.3	-1.9	-1.1
Fasting Glucose	1.0	1.2	3.1	0.5	-0.3	-1.6	-0.3	1.4	1.4	1.0	1.8	0.9	0.8	0.9
LDL Cholesterol	1.0	1.6	4.2	-1.2	-0.9	0.3	-2.1	-1.4	0.5	-1.3	-1.6	-1.3	-1.2	-1.2
Medication: Levothyroxine sodium	1.0	1.7	3.5	-1.5	1.2	0.8	-1.3	-1.1	-0.6	-1.4	-1.8	-1.4	-1.9	-1.0
Chronic bronchitis/emphysema (father)	1.0	1.2	2.4	-1.2	0.3	1.4	-1.0	-1.1	-1.6	-1.0	0.0	-1.0	-1.3	-1.1
Past tobacco smoking	1.0	1.8	5.3	1.5	-0.6	-2.3	0.4	0.3	2.1	1.4	-0.2	1.3	1.3	1.5
Allergy	1.0	2.3	5.8	1.8	-0.7	-0.3	1.5	1.2	0.6	1.8	0.9	1.9	2.4	2.0
Suffer from ‘nerves’	1.0	1.6	8.0	0.8	-0.2	-2.8	0.8	0.3	1.6	1.3	1.2	1.0	1.1	0.8
Medication: Aspirin	1.0	1.3	2.7	-1.0	-1.6	1.1	0.0	-1.2	-1.3	-1.1	-1.0	-1.0	-0.8	-1.4
Ever had bowel cancer screening	1.0	1.2	3.3	-0.9	-1.8	0.2	-1.1	-1.8	1.0	-0.8	0.6	-0.9	-0.7	-1.1
Prostate Cancer	0.9	1.3	5.2	-0.5	-0.4	2.3	-0.4	1.1	-2.2	-0.8	-1.1	-0.5	-0.4	-0.5
Type 2 Diabetes (T2D) (2018)	0.9	1.7	3.2	-1.8	-1.0	-0.0	-0.9	-1.5	-0.4	-1.6	-1.1	-1.8	-1.2	-1.7
Lung FVC	0.9	4.4	8.0	2.8	-0.4	-0.4	1.1	2.4	0.7	2.7	1.9	2.8	2.5	2.7
Severe depression (siblings)	0.9	1.0	7.2	0.1	-1.1	-0.9	-2.7	0.3	0.4	0.6	0.8	0.3	0.1	0.1
Had other major operations	0.9	1.0	4.9	-1.0	-0.0	1.0	-1.2	-0.3	-2.2	-1.0	-0.1	-0.9	-1.0	-0.7
Forced vital capacity (FVC)	0.9	3.5	7.5	2.7	0.3	-0.0	1.7	1.2	-0.0	2.4	1.7	2.7	2.1	2.4
Mouth/teeth dental problems	0.9	1.4	4.3	-0.9	-1.6	0.9	-0.3	-2.1	-1.2	-1.1	-0.5	-1.1	-1.3	-1.3
Forced expiratory volume in 1-second (FEV1)	0.9	2.9	6.0	2.5	-0.4	-0.3	1.7	1.0	0.2	2.2	1.4	2.5	1.9	2.2
Happiness	0.9	1.1	2.3	1.3	1.1	-0.2	0.7	1.2	-0.2	1.1	1.5	1.2	0.5	1.3
Emphysema/chronic bronchitis	0.9	1.0	7.8	-0.5	-0.2	0.7	-2.8	0.0	-0.3	-0.5	1.2	-0.5	-0.8	-0.3
Supplements: Vitamin C	0.9	1.1	4.6	0.7	-0.2	-0.2	-1.3	1.2	-0.5	0.9	2.1	0.9	0.9	0.9
Pain type(s) experienced in last month: Hip pain	0.9	1.1	2.5	-1.1	-0.6	1.0	-0.4	-1.3	-1.6	-1.3	-0.5	-1.2	-0.8	-1.2
Commuting to job workplace: Cycle	0.9	1.1	3.8	0.6	0.4	-1.6	-2.0	0.7	1.4	0.9	0.9	0.7	0.5	0.8
Relative age of first facial hair	0.8	1.7	10.0	-1.0	-3.2	0.7	-1.2	-1.2	0.5	-1.2	-0.5	-1.2	-0.8	-0.9
Medication: Metformin	0.8	1.2	2.9	-1.4	-1.1	-0.9	-0.6	-1.0	0.3	-1.1	-0.5	-1.4	-1.0	-1.7
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	2.1	-0.8	1.4	0.5	-0.9	-1.2	0.4	-0.8	-0.6	-0.8	-0.8	-1.1
Fluid intelligence score	0.8	1.6	5.8	1.5	0.7	0.0	0.7	2.4	0.5	1.4	-0.6	1.5	1.4	1.4
Birth weight	0.8	1.7	3.6	1.0	-0.1	-1.4	-0.7	0.8	1.9	1.6	1.7	1.4	1.3	1.3
Medication: Blood pressure	0.8	1.3	2.6	-1.3	-1.6	0.7	-0.8	-1.6	-0.7	-1.3	-0.5	-1.4	-0.5	-1.4
Illnesses of father: None of the above (group 1)	0.8	1.0	8.9	0.2	3.0	0.1	0.4	-0.1	-0.1	0.2	1.0	0.3	-0.5	0.3
Bipolar Disorder or Schizophrenia	0.7	1.7	7.6	-0.3	0.9	1.9	1.7	-0.7	-2.8	-0.9	-0.4	-0.6	-0.9	-1.1
Hypothyroidism (self reported)	0.7	1.7	4.6	-1.1	1.7	0.7	-2.1	-1.6	0.0	-1.1	-1.4	-1.0	-1.5	-0.8
Number of treatments/medications taken	0.7	1.2	3.0	-1.3	-0.3	0.5	-1.7	-0.7	-1.2	-1.2	-0.7	-1.3	-0.9	-1.3
Systolic blood pressure, automated reading	0.7	2.1	5.4	-1.5	-2.3	0.5	0.7	-1.3	-0.6	-1.7	-1.7	-1.7	-1.2	-1.6
Diabetes (mother)	0.7	0.9	3.4	-0.2	1.8	1.2	0.4	-0.9	-1.3	-0.6	-0.9	-0.3	-0.9	-0.6
Relative age voice broke	0.7	1.1	5.6	-0.7	-2.4	1.0	-0.1	-1.2	0.4	-1.0	-0.3	-0.9	-0.7	-0.8
Qualifications: CSEs or equivalent	0.7	0.9	3.0	-0.7	0.6	0.9	1.4	-1.7	-0.1	-0.9	-1.1	-0.8	-0.7	-0.6
Sitting height	0.7	4.7	8.5	2.8	0.2	-0.5	2.3	2.8	0.7	2.5	1.7	2.7	2.3	2.9
High blood pressure (mother)	0.7	0.9	2.0	0.8	-1.4	-1.2	0.9	0.6	0.8	0.7	-1.1	0.6	1.3	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	4.4	-0.3	-1.6	-2.1	-1.2	-0.7	1.5	0.4	0.6	0.0	0.6	0.1
Had menopause	0.7	0.8	6.9	-0.3	2.6	-0.7	0.7	-0.1	1.0	-0.1	-0.2	-0.1	-0.2	-0.0
Pain all over the body in last month	0.7	0.7	4.1	-0.1	1.1	0.5	0.7	-0.5	-2.0	-0.1	1.4	-0.0	0.1	0.0
Comparative body size at age 10	0.7	1.9	3.6	-1.9	-0.8	0.7	0.1	-1.7	-0.9	-1.8	-0.2	-1.9	-1.8	-1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	6.1	0.1	-0.6	-1.0	-2.5	-0.7	0.8	0.5	0.9	0.3	0.7	0.0
Pulse wave peak to peak time	0.7	0.8	4.7	0.4	1.0	-1.2	-0.2	0.2	0.6	0.7	2.2	0.5	-0.1	0.2
Smoking status: Previous	0.7	1.0	4.6	-0.8	1.1	2.1	0.3	0.3	-1.4	-1.0	0.1	-0.7	-0.6	-0.8
Diabetes diagnosed by doctor	0.7	1.2	2.9	-1.2	-1.7	0.4	-1.6	-0.6	-0.0	-1.2	-0.2	-1.2	-0.8	-1.4
Guilty feelings	0.7	1.0	5.2	-0.6	-2.3	-0.8	-0.8	-1.1	1.3	-0.3	-0.1	-0.6	-0.1	-1.0
Mother’s age at death	0.7	0.9	3.0	0.8	1.7	-0.9	0.2	1.5	0.9	0.9	0.6	0.9	0.1	0.8
Medication: Lisinopril	0.7	0.9	5.6	0.7	2.4	1.0	-0.2	0.9	-0.8	0.4	-0.2	0.7	0.0	0.9
Age started oral contraceptive pill	0.7	0.9	3.2	0.8	1.0	-1.2	-0.1	-0.0	1.8	1.0	0.5	0.9	0.6	0.9
Basal cell carcinoma (self-reported)	0.7	0.8	2.0	-1.0	-1.4	-0.1	-0.1	-1.0	0.1	-1.1	-0.4	-1.1	-0.9	-1.2
Schizophrenia (2018)	0.6	1.2	3.6	0.8	1.1	0.5	1.7	0.7	-1.8	0.5	1.9	0.6	0.3	0.1
Schizophrenia vs Biploar Disorder	0.6	0.8	3.3	0.3	0.0	0.8	-0.4	1.2	-1.8	0.3	1.6	0.5	0.1	0.2
Verbal and Numeric Reasoning (VNR)	0.6	1.5	5.2	1.6	0.5	0.2	0.5	2.3	0.5	1.4	-0.6	1.6	1.3	1.4
Body Mass Index (BMI) (2010)	0.6	0.8	2.8	0.6	-0.8	-1.7	1.2	-0.1	1.0	0.9	0.4	0.6	0.9	0.3
Waist Hip Ratio (WHR)	0.6	2.8	4.6	-1.8	-2.1	1.8	-1.0	-1.6	-0.9	-1.9	-0.8	-1.9	-1.7	-1.9
Systolic Blood Pressure	0.6	3.2	14.8	-1.3	-3.9	-0.2	-0.5	-1.9	-0.1	-1.9	-2.2	-1.9	-0.8	-1.5
Allergy or Eczema	0.6	1.6	3.3	-1.4	-1.0	-0.1	-1.5	-1.1	0.2	-1.5	-1.0	-1.5	-1.8	-1.7
Chronotype (morning person)	0.6	1.3	2.5	1.5	0.6	-0.9	1.6	0.5	0.3	1.2	1.2	1.3	1.1	1.6
Sensitivity / hurt feelings	0.6	1.0	3.1	1.1	-1.8	-0.3	0.4	0.5	0.6	0.9	-0.3	1.0	1.4	1.3
Ever had hysterectomy (womb removed)	0.6	0.7	3.1	0.1	-0.4	1.8	0.8	-0.7	-1.5	-0.2	-0.2	0.0	-0.6	0.2
Serious illness, injury or assault to yourself	0.6	0.7	2.6	0.9	-0.7	0.6	0.6	0.3	-0.1	0.7	-0.4	0.9	1.6	1.2
Waist circumference	0.6	2.0	3.6	-1.9	-1.9	1.3	-0.3	-0.9	-1.5	-1.1	1.9	-1.4	-0.8	-1.8
Nervous feelings	0.6	1.1	3.8	-1.2	-0.7	-1.9	-1.3	-1.1	0.9	-0.5	0.3	-1.0	-0.4	-1.0
Hair/balding pattern: Pattern 3	0.6	0.9	2.9	0.3	1.7	-0.1	-1.7	1.6	1.1	0.3	0.2	0.4	-0.1	0.6
Pulse wave Arterial Stiffness index	0.6	0.7	4.3	-0.3	-0.7	1.2	0.3	-0.2	-0.7	-0.7	-2.1	-0.5	0.1	-0.1
Leg fat percentage (right)	0.6	2.2	5.4	-2.0	-1.2	1.3	0.4	-1.2	-2.3	-1.4	1.4	-1.6	-1.0	-1.7
Number of full brothers	0.6	0.8	2.2	0.9	-1.0	-0.6	1.3	0.7	0.4	0.8	-0.2	0.8	1.5	0.8
Migraine (self-reported)	0.6	0.7	3.6	0.3	0.6	1.9	-0.4	0.6	-0.9	-0.1	-1.6	0.2	0.3	0.4
Age at last live birth	0.6	0.8	2.6	-0.7	-1.3	0.2	-1.2	-1.6	0.2	-0.6	-0.9	-0.7	-0.8	-0.9
Knee pain experienced in last month	0.6	0.9	2.3	-1.5	-0.4	-0.5	-1.2	-0.8	0.3	-0.9	-0.3	-1.3	-0.5	-1.3
Loneliness, isolation	0.6	0.8	5.1	-0.3	-2.2	-1.4	-1.1	-0.5	0.7	-0.0	-0.2	-0.2	0.2	-0.1
Medication: Aspirin	0.6	0.8	4.0	-0.6	-2.0	0.7	0.2	-0.9	-0.6	-0.7	-0.9	-0.7	-0.4	-0.9
Average weekly champagne plus white wine intake	0.6	0.8	1.5	1.1	-0.1	-1.0	0.8	0.7	0.4	1.2	0.3	1.1	1.2	1.1
Commuting to job workplace: Public transport	0.6	0.7	2.6	0.5	1.0	-1.2	0.4	0.7	0.6	0.7	1.6	0.6	0.7	0.3
Supplements: Fish oil (including cod liver oil)	0.6	0.8	2.2	-0.4	1.5	1.4	-0.5	0.3	-1.4	-0.5	0.7	-0.3	-0.9	-0.7
Medication: Bendroflumethiazide	0.6	0.9	1.6	-1.2	1.0	-0.5	0.5	-1.1	-0.5	-1.0	-1.3	-1.2	-0.6	-1.2
Medication: Paracetamol	0.6	0.9	1.8	-1.2	0.1	0.6	-0.8	-0.4	-1.3	-1.1	-0.2	-1.1	-1.2	-1.3
Leg fat percentage (left)	0.6	2.3	6.9	-1.8	-1.0	1.4	0.6	-1.2	-2.6	-1.2	1.7	-1.4	-1.0	-1.5
Unable to work because of sickness or disability	0.6	0.8	2.4	-1.1	-0.2	-0.3	-1.2	-0.8	-1.6	-0.9	-0.1	-1.0	-0.5	-0.8
Depressed Affect (Nagel 2018)	0.5	1.1	3.5	0.4	-1.9	-1.2	-1.3	0.1	0.2	1.0	1.5	0.7	1.1	0.5
Neuroticism (2016)	0.5	0.8	3.1	-0.7	-1.7	-1.8	-0.4	-0.4	0.6	-0.0	0.9	-0.5	0.0	-0.6
Rheumatoid Arthritis	0.5	0.7	3.3	0.4	-0.6	-1.8	-0.6	0.4	-0.1	0.9	1.1	0.6	0.9	0.2
Blood White Count	0.5	3.8	7.0	-2.2	-0.5	2.6	-0.1	-2.0	-2.4	-2.2	-1.6	-2.1	-1.7	-2.2
Cardiovascular Disease	0.5	1.7	13.0	-0.4	-3.6	-0.5	-1.6	-1.0	-0.3	-0.6	-0.3	-0.7	0.5	-0.9
Hand grip strength (left)	0.5	1.4	4.5	1.2	-1.5	0.1	2.1	0.9	-0.7	1.1	0.8	1.2	1.2	1.0
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.2	-0.6	0.8	0.8	0.3	-0.9	-0.8	-0.9	-1.1	-0.7	-0.9	-0.5
Qualifications: None of the above	0.5	1.0	2.0	-0.9	-1.1	1.1	-1.4	-0.8	-0.9	-1.1	-0.6	-1.0	-0.5	-1.0
Impedance of arm (right)	0.5	2.5	4.9	1.9	1.4	-2.2	0.4	1.1	1.7	1.9	0.6	1.8	1.3	1.9
Mouth/teeth dental problems: Dentures	0.5	0.9	4.0	0.5	1.7	-0.5	0.6	2.0	0.3	0.6	0.4	0.6	0.6	0.5
Hair/balding pattern: Pattern 4	0.5	1.1	4.5	1.1	0.7	0.1	2.1	1.0	-0.6	0.8	1.2	1.1	0.7	0.8
Blood clot in the leg (DVT)	0.5	0.6	2.6	-0.4	-1.6	-1.2	0.4	-0.9	1.1	0.1	-0.3	-0.2	0.2	-0.2
Glaucoma (self-reported)	0.5	0.6	1.6	0.8	0.0	-0.4	-0.3	0.7	0.4	0.7	1.3	0.8	1.0	0.9
Shortness of breath walking on level ground	0.5	0.6	1.7	0.7	-0.9	-0.3	-0.0	0.6	1.3	0.7	0.4	0.7	1.0	0.9
Neck or shoulder pain in last month	0.5	0.7	4.4	-0.5	-2.1	-0.1	-0.8	-1.3	0.4	-0.6	0.0	-0.6	-0.3	-0.4
Number of full sisters	0.5	0.7	6.5	-0.4	0.1	0.5	-2.6	-0.4	0.2	-0.2	0.1	-0.2	-0.3	-0.2
Breast cancer (self-reported)	0.5	0.6	1.8	0.6	1.1	-0.7	-0.6	0.3	1.4	0.4	-1.0	0.5	0.7	0.7
Osteoporosis (self-reported)	0.5	0.6	1.0	0.9	0.5	-0.7	1.0	-0.9	0.6	0.9	0.8	1.0	0.5	0.8
Medication: Atorvastatin	0.5	0.6	2.8	-0.5	-1.7	0.9	-1.1	-0.2	0.1	-0.6	-0.8	-0.6	-0.3	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	2.1	-0.5	-1.4	-1.4	0.4	-1.0	1.0	0.0	-0.2	-0.3	0.1	-0.3
Mean Putamen Volume	0.4	0.4	1.0	0.9	-0.6	0.2	0.6	1.0	0.4	0.6	-0.2	0.8	0.5	1.0
Fed-up feelings	0.4	0.8	3.7	0.6	-1.9	-0.5	-1.3	-0.4	-0.4	0.5	0.7	0.6	0.9	0.3
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.6	-0.4	-0.6	0.5	0.5	-1.3	-1.1	-0.3	-0.5	-0.4	-0.4	-0.3
Multivitamins +/- minerals	0.4	0.5	1.5	0.7	0.8	0.6	0.4	0.3	-0.5	0.5	1.2	0.7	0.6	0.6
Stomach or abdominal pain in last month	0.4	0.6	1.2	-0.9	-1.1	-0.3	-1.0	-0.2	-0.6	-0.7	0.2	-0.9	-0.8	-0.8
Supplements: Glucosamine	0.4	0.6	3.5	0.0	1.9	0.0	1.1	-0.4	-0.7	0.1	0.6	0.1	-0.6	0.4
Body mass index (BMI)	0.4	1.6	4.2	-1.4	-1.7	1.0	0.4	-0.7	-2.0	-0.6	2.0	-0.9	-0.3	-1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.8	2.8	-0.8	-0.6	1.2	-0.8	-0.8	0.0	-1.1	-1.7	-0.9	-0.6	-0.4
Heart attack	0.4	0.5	3.5	-0.3	-1.9	-0.4	-0.7	-0.6	0.3	-0.1	0.6	-0.2	-0.1	-0.8
Neuroticism score	0.4	0.7	2.0	0.4	-1.4	-1.2	-0.7	-0.3	0.1	0.9	1.1	0.7	0.9	0.6
Arm fat percentage (right)	0.4	1.5	4.5	-1.4	-1.6	0.7	0.6	-0.5	-2.0	-0.6	2.1	-0.9	-0.5	-1.1
Father’s age at death	0.4	0.5	3.6	-0.3	0.2	-1.9	-0.8	0.5	1.0	0.2	0.1	0.0	-0.3	0.3
Number of live births	0.4	0.6	1.4	-0.7	0.1	-1.1	-0.6	-0.6	1.2	-0.5	0.5	-0.6	-0.7	-1.1
Tense / ‘highly strung’	0.4	0.6	2.0	0.0	-1.1	-1.3	-1.4	0.3	-0.4	0.6	0.8	0.3	0.6	0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	3.2	-0.7	-0.1	-0.7	-1.8	-0.6	-0.7	-0.1	0.8	-0.4	-0.1	-0.8
Ever highly irritable/argumentative for 2 days	0.4	0.4	2.5	-0.5	-0.5	-0.7	-1.6	-0.7	-0.1	-0.3	-0.1	-0.4	-0.2	-0.6
Age at first live birth	0.4	0.7	2.2	-0.1	-1.3	1.5	-0.6	-1.0	-0.2	-0.4	-1.3	-0.2	-0.3	-0.1
Overall health rating	0.4	0.8	3.0	-1.0	-1.7	-0.4	-0.3	-1.2	-0.1	-0.5	1.2	-0.8	-0.2	-1.0
Leg pain on walking	0.4	0.5	2.2	0.5	0.2	0.3	0.4	-0.0	-0.8	0.7	1.5	0.8	0.5	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.1	0.8	1.1	-0.4	0.8	0.6	0.1	0.7	0.2	0.8	0.6	0.7
Arm fat percentage (left)	0.4	1.7	4.5	-1.6	-1.6	1.0	0.8	-0.7	-2.1	-0.9	1.7	-1.1	-0.7	-1.4
Mineral and other dietary supplements	0.4	0.5	3.1	0.0	-1.8	-0.6	-0.3	-0.0	0.8	-0.0	-1.1	-0.1	0.5	0.1
Miserableness	0.4	0.7	1.3	0.4	-1.2	-1.1	-0.7	-0.4	0.8	0.8	1.0	0.6	0.9	0.7
Number of operations (self-reported)	0.4	0.5	2.3	0.4	0.4	-0.6	-0.2	1.0	-0.8	0.7	1.5	0.6	0.5	0.3
Irritability	0.4	0.6	4.0	0.1	-0.9	0.4	-2.0	-0.3	-0.7	0.3	1.0	0.3	0.0	-0.3
Heart attack/myocardial infarction (self-reported)	0.4	0.5	3.5	-0.4	-1.9	-0.2	-0.6	-0.7	0.3	-0.3	0.3	-0.3	-0.2	-0.9
Heart disease (siblings)	0.4	0.4	1.1	-0.7	0.0	-0.2	-0.9	-0.3	0.5	-0.8	-1.0	-0.9	-0.4	-0.7
Leg fat mass (left)	0.4	1.4	4.0	-1.3	-1.4	1.2	0.7	-0.5	-1.9	-0.6	2.0	-0.8	-0.3	-1.0
Intelligence (Savage-Jansen 2018)	0.3	1.1	4.5	1.1	1.3	-0.3	0.6	2.1	0.6	1.0	0.5	1.1	0.6	0.9
Neuroticism (Nagel 2018)	0.3	0.8	2.5	0.2	-1.4	-1.2	-1.6	0.1	0.6	0.7	0.8	0.4	1.0	0.3
Crohns Disease (2012)	0.3	0.5	2.4	-0.4	0.0	0.3	-0.5	-0.4	1.3	-0.5	-1.5	-0.4	-0.4	0.1
HDL Cholesterol	0.3	0.6	1.5	0.2	1.2	-0.3	-1.2	0.7	-0.7	0.5	1.2	0.5	0.0	0.5
Schizophrenia (2014)	0.3	0.7	2.5	-0.3	0.3	1.3	0.7	-0.7	-1.6	-0.7	0.2	-0.5	-0.9	-0.9
Neuroticism	0.3	0.6	2.4	0.3	-1.6	-0.7	-0.8	0.1	-0.2	0.6	1.3	0.4	0.8	0.4
Hand grip strength (right)	0.3	0.9	4.5	1.0	-0.7	0.4	2.1	0.8	-0.6	0.6	0.1	0.8	0.6	1.1
Hayfever, allergic rhinitis or eczema	0.3	0.6	2.2	-0.7	-0.2	0.6	-0.3	-0.5	-0.8	-0.9	-0.4	-0.8	-1.5	-1.1
Number of incorrect matches in round	0.3	0.5	1.4	-0.2	-1.1	0.8	-1.2	0.1	0.0	-0.7	-1.2	-0.3	-0.5	-0.6
Diabetes (self-reported)	0.3	0.5	3.2	-0.4	-1.8	-0.3	-0.7	-0.2	0.4	-0.5	0.3	-0.5	-0.4	-0.6
Illnesses of siblings	0.3	0.4	1.3	-0.4	0.9	1.1	0.2	-0.8	-0.6	-0.4	-1.0	-0.3	-0.1	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	1.3	-1.1	-0.5	-0.4	-1.1	-0.8	-0.4	-0.4	-0.2	-0.7	-0.3	-0.7
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.9	0.0	-1.4	0.8	-1.1	-0.3	-0.8	-0.2	-0.4	-0.0	0.0	-0.0
Depression (self-reported)	0.3	0.3	1.2	-0.1	0.5	-1.1	-0.8	-0.3	0.1	0.5	0.8	0.2	0.7	0.1
Prospective memory result	0.3	0.4	3.5	-0.3	0.5	0.6	0.4	-1.9	0.5	-0.2	0.3	-0.2	-0.1	-0.0
Impedance of arm (left)	0.3	1.5	3.2	1.5	1.4	-1.8	0.7	0.8	1.2	1.4	0.3	1.3	0.8	1.4
Arm fat mass (right)	0.3	1.3	5.3	-1.1	-1.5	0.9	0.6	-0.2	-1.9	-0.4	2.3	-0.6	-0.1	-0.9
Standing height	0.3	2.9	5.2	2.3	0.9	-0.6	1.5	2.2	1.3	1.9	0.2	2.1	2.1	2.1
Peak expiratory flow (PEF)	0.3	0.6	2.9	0.4	-1.3	0.3	1.7	0.1	-1.0	0.3	0.7	0.4	-0.1	-0.0
Medication: Amlodipine	0.3	0.4	1.3	-0.7	-1.1	0.0	-0.1	-1.1	0.2	-0.8	-0.0	-1.0	-0.1	-0.4
Body fat percentage	0.3	1.3	5.0	-1.2	-1.4	0.7	0.5	-0.4	-1.9	-0.5	2.2	-0.7	-0.2	-0.9
Exposure to tobacco smoke outside home	0.3	0.3	1.7	-0.0	0.3	1.3	-0.6	-0.1	-1.0	-0.2	-0.8	0.0	0.0	-0.0
Number of children fathered	0.3	0.3	0.9	0.1	0.6	-0.6	1.0	0.9	0.6	0.1	0.5	0.1	0.1	0.5
Medication for pain relief, constipation, heartburn	0.3	0.4	1.8	0.3	0.9	-0.9	0.6	0.0	1.3	0.3	0.3	0.3	0.2	0.7
Whole body fat mass	0.3	1.1	5.0	-1.0	-1.6	0.5	0.4	-0.1	-1.4	-0.2	2.2	-0.5	0.2	-0.7
Leg fat mass (right)	0.3	1.3	3.4	-1.4	-1.4	1.0	0.6	-0.6	-1.6	-0.7	1.8	-0.9	-0.2	-1.1
Long-standing illness, disability or infirmity	0.3	0.5	2.3	-0.6	-1.5	-0.8	0.0	-0.6	-0.3	-0.3	1.2	-0.5	0.2	-0.5
Back pain experienced in last month	0.3	0.4	1.0	-0.1	-0.8	1.0	0.5	-0.8	-0.9	0.0	0.9	0.1	0.2	-0.3
Arm fat mass (left)	0.3	1.3	4.8	-1.0	-1.6	0.8	0.9	-0.2	-1.8	-0.3	2.2	-0.5	0.1	-0.8
Medication: Blood pressure	0.3	0.5	1.8	-0.7	-0.6	-0.8	-1.2	-0.2	-0.3	-0.6	-1.3	-0.7	-0.1	-0.6
Alcohol drinker status: Never	0.3	0.3	1.6	-0.4	-1.3	0.3	-0.3	0.2	-0.1	-0.5	-0.7	-0.4	-0.6	-0.6
Risk taking	0.3	0.4	1.4	0.7	0.0	0.4	0.7	-0.2	0.2	0.7	0.5	0.7	1.2	0.6
Vascular/heart problems diagnosed by doctor	0.3	0.8	5.2	0.3	2.3	0.3	1.4	-0.0	0.5	0.3	0.4	0.4	-0.6	0.5
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.1	0.1	1.1	-0.6	0.6	1.0	0.3	0.4	0.4	0.2	0.3	-0.2
Pain experienced in last month	0.3	0.6	1.6	-0.5	1.2	0.1	0.5	-0.3	0.5	-0.9	-1.3	-0.8	-0.8	-0.6
Pack years of smoking	0.3	0.4	1.2	0.7	0.2	-0.3	0.0	-0.2	0.6	0.6	-0.7	0.6	1.1	1.0
Worry (Nagel 2018)	0.2	0.4	2.1	-0.6	0.0	-1.4	-1.4	-0.4	0.3	0.0	0.1	-0.3	0.1	-0.3
Ovarian Cancer	0.2	0.3	0.8	-0.2	0.3	0.4	-0.9	-0.8	-0.2	-0.2	-0.7	-0.2	-0.6	-0.3
HbA1C	0.2	0.3	0.8	0.1	0.9	0.6	0.9	-0.5	-0.4	-0.3	0.6	-0.2	-0.3	-0.2
BMI	0.2	1.2	6.7	-1.2	-1.2	0.4	-0.4	-1.0	-1.3	-0.2	2.6	-0.6	0.0	-1.0
Medication for hormone replacement therapy	0.2	0.2	1.1	0.2	-1.1	-0.2	0.8	-0.4	-0.0	0.1	0.2	0.1	-0.1	0.4
Vitamin and mineral supplements	0.2	0.3	1.8	-0.5	-0.2	0.1	0.4	-0.4	0.4	-0.5	-1.3	-0.5	-0.5	-0.3
Medication: Co-codamol	0.2	0.2	0.9	-0.0	-0.5	0.8	0.4	0.8	-0.9	0.1	0.2	0.0	-0.0	-0.3
Pack years adult smoking proportion	0.2	0.3	0.8	0.5	0.3	-0.1	0.5	-0.3	-0.1	0.4	-0.7	0.4	0.8	0.9
Trunk fat percentage	0.2	1.0	5.5	-0.7	-1.0	0.4	0.7	-0.1	-1.6	-0.1	2.3	-0.3	0.2	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.8	-0.2	-0.3	1.1	-0.4	-0.3	-0.4	-0.6	-1.3	-0.3	-0.1	0.1
High blood pressure	0.2	0.5	2.8	-0.4	-1.7	-0.4	-1.3	-0.1	-0.4	-0.3	-0.4	-0.5	0.5	-0.4
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.5	0.3	-0.2	-0.1	0.7	0.7	-0.5	0.4	0.5	0.4	0.6	0.2
Medication: Atenolol	0.2	0.2	0.9	-0.3	-0.9	0.5	-0.5	-0.2	-0.3	-0.3	-0.8	-0.3	0.5	-0.2
Trunk fat mass	0.2	1.0	5.6	-0.6	-1.3	0.6	0.8	0.1	-1.5	0.0	2.4	-0.2	0.4	-0.4
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	1.4	-0.2	-0.8	-0.3	-1.2	-0.1	0.1	0.0	-0.1	-0.1	0.4	-0.1
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	1.3	-0.0	0.4	-0.0	0.8	-0.1	-1.2	-0.0	-0.5	-0.0	-0.4	-0.5
Weight	0.2	0.9	4.4	-0.3	-1.4	0.7	0.9	0.3	-1.3	0.3	2.1	0.1	0.6	-0.1
Hip circumference	0.2	1.0	8.6	-0.3	-0.6	-0.3	0.4	0.4	-0.9	0.6	2.9	0.3	0.7	-0.1
Worrier / anxious feelings	0.2	0.4	1.6	-0.2	-0.1	-1.1	-1.3	-1.1	0.7	0.0	0.3	-0.1	0.1	-0.1
Falls in the last year	0.2	0.2	1.0	-0.1	0.2	-0.1	-0.4	-0.8	0.3	0.4	1.0	0.2	0.4	-0.2
Pulse rate	0.2	0.3	1.1	0.2	-0.5	1.0	0.3	-0.8	-1.0	-0.0	0.1	0.1	0.2	0.3
Qualifications: A levels/AS levels or equivalent	0.2	0.4	2.1	-0.1	0.5	0.8	1.0	1.5	-0.5	-0.1	-0.3	-0.1	-0.7	-0.0
Length of working week for main job	0.2	0.2	0.6	-0.8	-0.7	-0.3	-0.1	-0.6	0.2	-0.4	0.5	-0.6	-0.2	-0.5
Exposure to tobacco smoke at home	0.2	0.2	1.1	-0.1	-0.7	1.1	0.4	-0.7	0.4	-0.3	-0.1	-0.2	0.1	-0.4
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	1.0	-0.7	1.0	-0.7	0.4	0.7	0.7	-0.2	-0.5	-0.5	-0.7	-0.4
High blood pressure (siblings)	0.2	0.3	1.1	-0.3	0.2	-1.1	0.1	0.0	0.0	-0.3	0.8	-0.4	-0.6	-0.6
Worry too long after embarrassment	0.2	0.3	0.7	-0.4	-0.8	-0.4	0.2	-0.8	0.3	-0.4	-0.6	-0.5	0.2	-0.6
Medication: Ibuprofen	0.2	0.2	0.6	0.6	-0.7	0.4	-0.3	0.2	-0.2	0.4	0.1	0.6	0.6	0.4
Medication: Omeprazole	0.2	0.3	0.6	-0.8	0.5	0.2	0.1	0.6	-0.6	-0.4	0.0	-0.5	-0.5	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.6	-0.3	-0.6	-0.3	-0.4	0.5	0.6	-0.1	0.8	-0.2	-0.6	-0.6
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.9	-0.2	-0.9	0.2	-0.0	-0.7	-0.6	0.1	-0.2	-0.1	0.4	0.0
Hypertension (Self-reported)	0.2	0.5	2.8	-0.3	-1.7	-0.6	-1.0	-0.1	-0.3	-0.2	-0.3	-0.4	0.6	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.5	-0.3	1.2	0.0	-0.5	0.1	-1.1	-0.3	-1.1	-0.3	-0.2	-0.5
Medication for cholesterol	0.2	0.3	0.5	0.6	0.5	0.5	0.0	0.5	0.7	0.5	0.2	0.6	0.4	0.7
Medication: Gliclazide	0.2	0.2	1.0	-0.3	0.3	-1.0	-0.5	0.2	0.8	0.0	-0.2	-0.1	0.2	-0.6
Ever taken oral contraceptive pill	0.2	0.2	1.3	0.3	-1.1	0.3	-0.4	-0.2	0.8	-0.2	0.2	-0.1	-0.0	0.1
Financial situation satisfaction	0.2	0.2	1.0	-0.1	-0.4	1.0	-0.6	0.1	-0.9	-0.1	0.4	-0.0	0.3	0.1
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.9	0.0	0.1	0.6	0.7	0.4	-0.8	-0.1	-0.9	-0.0	-0.4	0.2
Myopia	0.2	0.3	1.1	-0.7	-0.6	-0.2	-1.1	-0.5	0.2	-0.3	0.1	-0.6	-0.5	-1.0
Impedance of whole body	0.2	1.0	2.8	1.2	1.7	-1.4	0.2	0.4	0.9	1.0	-0.2	1.0	0.7	1.1
Reaction Time	0.1	0.2	0.4	0.3	-0.4	-0.3	-0.7	0.5	-0.6	0.3	0.1	0.3	0.4	0.5
Triglycerides	0.1	0.2	0.8	-0.1	-0.9	-0.6	-0.2	0.0	0.4	-0.1	0.6	-0.3	-0.5	-0.4
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.5	-0.6	-0.3	0.7	-0.5	0.3	0.0	0.0	0.0	0.0	0.0	0.0
Blood Red Count	0.1	0.9	4.7	-0.7	2.2	-1.7	0.6	-0.2	0.7	0.2	0.9	-0.2	-0.5	0.2
Lung FEV1/FVC ratio	0.1	0.5	3.5	0.1	0.0	-0.9	1.9	0.4	0.5	0.4	-0.1	0.2	0.4	0.6
Average weekly spirits intake	0.1	0.1	0.6	-0.3	0.8	-0.3	0.0	-0.1	0.6	-0.1	0.3	-0.2	-0.1	-0.3
Diabetes (father)	0.1	0.1	0.3	0.0	0.3	0.1	0.3	0.5	-0.3	-0.0	-0.4	-0.0	-0.2	0.1
Impedance of leg (right)	0.1	0.5	1.8	-0.3	1.3	-0.3	-1.3	-0.7	-0.0	-0.5	-0.9	-0.6	-0.5	-0.3
Leg fat-free mass (left)	0.1	0.6	1.8	0.1	-1.2	0.6	1.2	0.6	-0.3	0.5	1.3	0.4	0.7	0.2
Age when periods started (menarche)	0.1	0.2	0.8	0.5	0.4	0.4	0.1	0.0	-0.9	0.3	-0.0	0.4	0.4	0.5
Impedance of leg (left)	0.1	0.4	3.1	0.0	1.8	-0.3	-0.6	-0.6	-0.4	-0.2	-0.5	-0.2	-0.3	0.0
Leg predicted mass (left)	0.1	0.5	1.7	0.0	-1.1	0.6	1.1	0.6	-0.3	0.4	1.3	0.3	0.6	0.2
Trunk fat-free mass	0.1	0.3	1.1	0.1	-1.0	0.7	0.3	0.7	-0.3	0.3	0.9	0.3	0.7	0.1
Illnesses of mother	0.1	0.1	1.0	-0.5	-0.0	-0.3	0.1	-0.3	-0.2	-0.0	1.0	-0.3	0.1	-0.2
Trunk predicted mass	0.1	0.3	1.0	0.1	-1.0	0.7	0.3	0.7	-0.3	0.3	0.9	0.3	0.6	0.1
Breastfed as a baby	0.1	0.2	0.7	0.6	0.1	-0.3	0.4	-0.2	0.2	0.4	-0.9	0.4	0.5	0.2
Headache pain in last month	0.1	0.1	0.4	-0.2	0.7	0.3	-0.3	-0.4	-0.2	-0.1	-0.2	-0.1	-0.4	-0.2
Arm fat-free mass (right)	0.1	0.5	1.7	-0.5	-0.8	1.3	0.9	0.1	-0.8	-0.4	0.8	-0.3	0.2	-0.5
Mean time to correctly identify matches	0.1	0.2	0.7	-0.5	-0.1	0.0	-0.8	0.3	-0.3	-0.5	-0.8	-0.6	-0.5	-0.2
Arm predicted mass (right)	0.1	0.4	1.5	-0.3	-0.9	1.2	0.9	0.2	-0.7	-0.2	0.9	-0.1	0.3	-0.4
Pulse rate, automated reading	0.1	0.2	1.4	-0.2	-1.2	0.0	0.5	-0.2	-0.6	-0.1	-0.2	-0.1	-0.1	0.2
Alcohol intake frequency.	0.1	0.2	0.6	-0.3	0.3	0.1	0.5	-0.3	-0.8	-0.1	-0.7	-0.2	-0.3	-0.3
Comparative height size at age 10	0.1	0.6	1.2	0.9	1.0	-0.2	0.7	0.8	0.8	0.7	-0.3	0.9	1.1	0.7
Whole body fat-free mass	0.1	0.5	1.3	0.2	-0.9	0.7	0.8	0.7	-0.4	0.4	1.2	0.4	0.8	0.2
Leg fat-free mass (right)	0.1	0.8	2.2	0.4	-1.1	0.4	1.5	0.8	-0.3	0.7	1.5	0.7	0.9	0.5
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.4	-0.1	0.4	0.6	0.7	0.0	0.5	0.2	0.1	0.2	-0.0	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.4	0.2	0.5	-0.1	-0.3	-0.2	-0.3	0.2	0.6	0.2	0.0	0.4
Whole body water mass	0.1	0.5	1.4	0.2	-1.0	0.7	0.8	0.7	-0.4	0.4	1.2	0.4	0.8	0.2
Leg predicted mass (right)	0.1	0.8	2.3	0.4	-1.0	0.4	1.5	0.7	-0.3	0.7	1.5	0.7	0.9	0.4
Hearing aid user	0.1	0.1	0.5	0.1	0.1	-0.3	-0.7	0.4	0.3	0.3	0.7	0.2	0.3	-0.0
Basal metabolic rate	0.1	0.6	2.2	-0.0	-1.3	0.7	0.7	0.6	-0.7	0.3	1.5	0.3	0.7	0.0
Arm fat-free mass (left)	0.1	0.6	1.9	-0.0	-1.1	0.8	0.9	0.6	-0.7	0.2	1.4	0.2	0.7	0.1
Arm predicted mass (left)	0.1	0.6	2.1	0.0	-1.1	0.8	1.1	0.6	-0.8	0.3	1.4	0.3	0.8	0.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.2	0.1	0.0	-0.4	-0.5	-0.2	0.0	0.0	0.0	0.0	0.0	0.0
Heel T-Score	0.0	0.2	0.9	-0.1	-1.0	0.2	-0.4	-0.2	0.6	-0.2	-0.8	-0.2	0.1	0.5
Height	0.0	0.9	2.3	1.2	0.3	-0.5	0.2	-0.4	1.5	0.9	-0.9	1.0	1.3	1.0
Hair Pigment	0.0	1.1	4.4	-0.1	-0.3	2.1	-1.2	-0.9	-1.8	-0.6	-0.9	-0.3	-0.8	-0.1
Tanning	0.0	0.4	2.3	-0.4	-0.1	-0.2	-0.7	-1.5	0.6	-0.2	-1.0	-0.3	0.3	-0.2
Mouth/teeth dental problems: Loose teeth	0.0	0.0	0.1	0.1	0.3	-0.1	-0.0	0.0	0.3	0.2	0.2	0.1	0.2	0.2
Eye problems/disorders: Cataract	0.0	0.1	0.2	0.4	0.4	-0.1	0.3	0.0	0.0	0.2	-0.0	0.2	0.1	0.2

Hub : Genes

MIIP

Models

Trait associations