Best TWAS P=4.66e-10 · Best GWAS P=5.19e-18 conditioned to 1.65e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | ACTR2 | 0.21 | 0.10 | lasso | 6 | 0.08 | 3.4e-05 | -4.9 | 5.5 | 3.3e-08 | -0.36 | 0.68 | 0.21 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | ACTR2 | 0.17 | 0.14 | lasso | 5 | 0.14 | 1.4e-17 | -4.8 | 5.2 | 2.7e-07 | -0.35 | 1.00 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Soft Tissue Sarcoma | SPRED2 | 0.06 | 0.01 | blup | 93 | 0.02 | 1.3e-02 | -7.5 | -6.2 | 4.7e-10 | 0.67 | 0.07 | 0.29 | TRUE |