[Hub]/) : Traits : Blood Eosinophil Count :

chr2:70,596,291-72,348,725

Best TWAS P=1.68e-12 · Best GWAS P=2.75e-12 conditioned to 5.94e-11

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ZNF638 0.06 0.01 bslmm 559 0.02 1.8e-03 -3.2 -5.7 1.6e-08 -0.21 0.33 0.03 FALSE
2 GTEx Esophagus Mucosa NAGK 0.53 0.34 lasso 8 0.51 1.7e-38 -4.9 6.5 7.1e-11 0.06 0.06 0.94 FALSE
3 GTEx Esophagus Mucosa MCEE 0.14 0.07 lasso 7 0.06 1.0e-04 -6.7 6.5 5.6e-11 0.11 0.00 1.00 FALSE
4 GTEx Nerve Tibial NAGK 0.13 0.10 lasso 4 0.08 4.7e-06 -6.8 6.9 6.0e-12 0.06 0.00 1.00 FALSE
5 GTEx Spleen NAGK 0.38 0.14 lasso 11 0.14 1.7e-04 -5.5 6.3 2.3e-10 0.06 0.01 0.93 FALSE
6 GTEx Spleen PAIP2B 0.36 -0.01 enet 28 0.07 7.4e-03 2.7 5.3 1.5e-07 -0.01 0.05 0.44 FALSE
7 METSIM Adipose NAGK 0.15 0.04 enet 30 0.11 2.5e-16 -4.9 7.1 1.7e-12 0.06 0.13 0.87 TRUE
8 YFS Blood NAGK 0.43 0.45 enet 15 0.49 4.3e-186 -4.9 5.6 2.6e-08 0.05 0.99 0.01 FALSE
9 The Cancer Genome Atlas Bladder Urothelial Carcinoma NAGK 0.06 0.02 blup 54 0.04 2.0e-04 -6.2 5.4 5.9e-08 0.09 0.02 0.85 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma NAGK 0.03 0.04 lasso 5 0.04 4.2e-08 -6.7 6.8 1.3e-11 0.08 0.00 1.00 FALSE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NAGK 0.19 0.12 blup 55 0.16 1.6e-17 -6.2 6.8 1.4e-11 0.07 0.03 0.97 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NAGK 0.06 0.03 blup 55 0.06 4.6e-07 -6.1 6.7 2.0e-11 0.08 0.01 0.99 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma NAGK 0.06 0.03 blup 55 0.05 2.2e-06 -6.2 6.7 2.5e-11 0.08 0.01 0.99 FALSE
14 The Cancer Genome Atlas Lung Adenocarcinoma NAGK 0.06 0.05 blup 55 0.05 7.8e-07 -4.9 5.4 5.8e-08 0.03 0.54 0.45 FALSE
15 The Cancer Genome Atlas Lung Squamous Cell Carcinoma NAGK 0.15 0.09 blup 55 0.11 1.1e-12 -6.4 6.7 2.8e-11 0.05 0.01 0.99 FALSE
16 The Cancer Genome Atlas Lung Squamous Cell Carcinoma OR7E91P 0.05 0.02 enet 12 0.05 4.5e-06 -3.4 5.7 1.2e-08 0.10 0.02 0.93 FALSE
17 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma NAGK 0.05 0.05 lasso 1 0.02 2.6e-02 -6.2 6.2 5.0e-10 0.06 0.03 0.75 FALSE
18 The Cancer Genome Atlas Thyroid Carcinoma NAGK 0.11 0.06 lasso 3 0.05 6.2e-06 -4.9 5.4 5.9e-08 0.05 0.64 0.13 FALSE