TWAS hub - ACTR2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0600	0.0210	9.5e-04	0.044	0.027	0.040	0.029	0.043	3.9e-06	2.8e-04	1.1e-05	1.4e-04	5.3e-06
2	GTEx	Adipose Subcutaneous	0.1660	0.0460	1.7e-05	0.087	NA	0.068	NA	0.088	1.4e-07	NA	3.2e-06	NA	1.1e-07
3	GTEx	Artery Aorta	0.1740	0.0620	4.1e-03	0.130	NA	0.112	NA	0.108	1.2e-07	NA	1.0e-06	NA	1.5e-06
4	GTEx	Artery Tibial	0.1659	0.0578	1.5e-03	0.069	NA	0.072	NA	0.068	4.5e-06	NA	2.9e-06	NA	5.0e-06
5	GTEx	Cells Transformed fibroblasts	0.1940	0.0540	7.0e-05	0.050	NA	0.057	NA	0.075	1.1e-04	NA	4.2e-05	NA	2.7e-06
6	GTEx	Heart Atrial Appendage	0.1460	0.0630	7.0e-03	0.016	NA	0.022	NA	0.052	6.3e-02	NA	3.6e-02	NA	2.4e-03
7	GTEx	Nerve Tibial	0.1238	0.0496	3.4e-03	0.059	NA	0.059	NA	0.064	5.2e-05	NA	4.9e-05	NA	2.5e-05
8	GTEx	Skin Not Sun Exposed Suprapubic	0.2070	0.0640	3.9e-04	0.098	NA	0.067	NA	0.081	5.2e-06	NA	1.6e-04	NA	3.5e-05
9	GTEx	Thyroid	0.1030	0.0410	5.3e-03	0.096	NA	0.100	NA	0.102	8.4e-08	NA	4.6e-08	NA	3.5e-08
10	METSIM	Adipose	0.0663	0.0266	2.5e-03	0.043	0.010	0.020	0.018	0.036	4.2e-07	1.1e-02	4.6e-04	9.0e-04	3.8e-06
11	ROSMAP	Brain Pre-frontal Cortex	0.1678	0.0346	3.5e-12	0.136	0.103	0.127	0.135	0.140	4.8e-17	3.7e-13	5.6e-16	6.2e-17	1.4e-17
12	TCGA	Breast Invasive Carcinoma	0.0286	0.0152	1.5e-03	0.007	0.014	0.013	NA	0.011	1.3e-02	5.2e-04	6.8e-04	NA	1.7e-03
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.0883	0.0356	4.4e-07	0.083	0.073	0.089	NA	0.085	1.2e-09	1.2e-08	3.1e-10	NA	7.7e-10
14	TCGA	Brain Lower Grade Glioma	0.0278	0.0187	9.9e-03	0.031	0.012	0.011	NA	0.027	1.6e-04	1.3e-02	1.7e-02	NA	4.5e-04
15	TCGA	Lung Adenocarcinoma	0.1104	0.0514	1.5e-06	0.047	0.057	0.059	NA	0.053	3.3e-06	3.0e-07	1.8e-07	NA	7.0e-07
16	TCGA	Thyroid Carcinoma	0.1190	0.0500	4.0e-05	0.028	0.057	0.053	NA	0.047	8.6e-04	3.0e-06	6.9e-06	NA	2.1e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Medication: Co-codamol	6.0	7.0	12.0	-2.9	-3.3	-2.1	-3.0	-2.6	-3.3	-3.0	-3.4	-1.9	-0.5	-3.5	-1.8	-3.1	-2.8	-1.9	-0.8
Ever smoked	5.8	10.1	13.2	3.1	3.6	3.4	3.6	2.9	3.4	3.5	3.5	2.7	3.0	3.6	3.0	3.1	3.0	2.4	2.7
Medication: Bendroflumethiazide	5.0	7.6	13.8	2.0	2.1	3.1	2.6	2.8	2.1	2.6	2.0	3.4	3.5	2.1	3.4	2.3	2.8	2.6	3.7
Reason for reducing amount of alcohol drunk: Health precaution	4.7	5.4	9.1	1.8	2.3	2.1	2.2	2.6	2.6	2.7	1.9	2.1	1.5	2.2	3.0	1.9	3.0	2.1	2.7
Headache pain in last month	4.0	6.8	11.3	-2.0	-2.2	-3.3	-2.4	-2.5	-2.5	-2.4	-2.8	-3.0	-3.4	-2.5	-2.4	-2.8	-2.0	-2.6	-2.6
Heel bone mineral density (BMD) T-score, automated (left)	3.9	8.8	12.3	-3.2	-3.0	-2.6	-3.3	-2.8	-3.5	-3.4	-3.5	-2.7	-2.4	-3.2	-2.6	-3.5	-3.0	-2.0	-2.4
Osteoarthritis (self-reported)	3.8	4.9	8.8	-2.8	-2.6	-2.1	-2.3	-1.9	-2.7	-2.4	-3.0	-1.7	-1.2	-2.8	-1.5	-2.7	-1.9	-1.2	-1.0
Qualifications: College or University degree	3.3	10.3	15.5	2.8	3.5	3.2	3.9	3.9	3.8	3.5	3.3	2.6	1.6	3.5	2.6	3.1	3.4	3.5	1.9
Rheumatoid Arthritis	3.2	4.4	10.2	3.0	2.4	1.8	2.1	0.9	2.1	2.1	3.1	1.9	1.6	3.0	0.6	3.2	1.0	1.3	0.3
Birth weight of first child	3.2	5.8	10.5	-1.8	-2.3	-2.9	-2.0	-1.9	-2.1	-2.3	-2.0	-2.5	-3.0	-1.9	-3.2	-1.9	-2.3	-2.6	-3.0
Pain experienced in last month	3.2	5.4	8.3	1.6	2.5	2.2	2.5	2.6	2.4	2.6	2.2	2.2	1.7	2.4	2.3	2.1	2.6	2.9	1.9
Average weekly spirits intake	2.9	3.6	5.4	-1.7	-1.9	-1.7	-1.5	-2.0	-2.2	-2.3	-2.1	-1.7	-1.0	-2.3	-1.6	-2.0	-2.3	-2.1	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	2.8	6.4	9.3	-2.5	-2.7	-2.3	-2.6	-2.3	-3.0	-2.9	-2.8	-2.2	-2.0	-2.7	-2.5	-2.7	-2.9	-1.3	-2.3
Number of full brothers	2.8	3.5	5.1	1.2	2.0	2.1	2.2	2.0	1.9	2.2	1.6	2.0	1.6	1.6	1.9	1.7	2.2	1.7	1.8
Illnesses of father: Heart disease	2.8	3.9	5.7	1.6	1.7	1.5	2.4	2.3	1.8	2.3	1.7	2.2	1.8	1.8	2.2	1.9	2.2	2.1	2.1
Average weekly fortified wine intake	2.7	3.2	5.8	-2.4	-1.9	-2.0	-1.6	-1.5	-2.4	-2.2	-2.0	-0.7	-0.2	-2.3	-1.7	-1.6	-2.2	-1.2	-0.8
Length of working week for main job	2.7	3.0	3.9	1.9	1.7	1.9	2.0	1.9	1.7	1.9	1.8	1.8	1.0	1.7	1.7	2.0	1.8	1.2	1.3
Hypothyroidism/myxoedema (self-reported)	2.7	5.3	7.8	2.5	2.8	1.9	1.6	2.5	2.8	2.8	2.4	1.8	0.9	2.7	2.5	2.2	2.8	1.8	2.0
Angina (self-reported)	2.7	3.6	11.2	0.6	1.0	2.7	1.6	1.7	1.0	1.4	1.0	2.4	3.3	0.9	2.4	1.4	1.4	1.4	3.1
Angina	2.6	3.4	10.5	0.5	0.9	2.6	1.4	1.7	1.0	1.3	0.9	2.3	3.2	0.8	2.5	1.2	1.5	1.3	3.1
Illnesses of siblings	2.6	3.6	5.5	-2.1	-2.2	-1.8	-2.4	-1.4	-1.9	-2.1	-2.1	-1.7	-1.6	-1.8	-2.0	-2.0	-1.9	-1.0	-1.9
Medication: Paracetamol	2.5	4.2	7.9	-1.3	-1.1	-2.5	-1.9	-1.9	-1.6	-1.7	-1.5	-2.7	-2.8	-1.4	-2.6	-1.8	-1.8	-2.5	-2.6
Commuting to job workplace: Public transport	2.5	2.9	6.4	1.9	2.5	1.8	1.6	1.9	1.8	2.1	2.1	0.8	0.3	2.3	0.9	2.0	1.7	1.2	0.3
Age started oral contraceptive pill	2.5	3.1	5.2	-2.0	-2.2	-1.4	-1.7	-1.4	-1.8	-2.0	-2.3	-1.8	-1.3	-2.1	-1.1	-2.3	-1.2	-1.9	-0.8
Heart disease (siblings)	2.5	3.0	4.5	1.6	1.7	1.9	2.0	1.5	1.7	1.6	1.6	1.8	1.8	1.6	2.1	1.6	1.6	1.8	1.9
Allergy or Eczema	2.4	6.4	13.6	2.0	2.2	3.0	1.7	2.9	2.3	2.5	2.4	3.3	2.3	2.3	2.2	2.7	2.3	3.7	1.8
Hypothyroidism (self reported)	2.4	5.6	9.1	2.8	3.0	1.6	1.5	2.5	2.9	2.9	2.7	1.7	0.7	3.0	2.4	2.3	2.9	1.8	1.6
Depression (self-reported)	2.4	2.9	6.0	2.4	2.1	1.1	1.1	2.0	2.3	2.2	1.7	0.0	-1.0	2.1	1.7	1.2	2.4	0.6	0.5
Leg pain on walking	2.4	3.0	6.6	-2.4	-2.2	-0.3	-2.0	-1.2	-2.3	-2.1	-2.5	-0.5	0.3	-2.6	-0.4	-2.4	-1.4	-0.8	0.5
Past tobacco smoking	2.3	4.3	7.6	-1.7	-2.2	-2.0	-2.8	-1.8	-2.2	-2.2	-2.3	-1.8	-2.3	-2.3	-1.9	-1.9	-1.9	-1.5	-2.0
Back pain experienced in last month	2.2	3.3	6.2	-2.2	-2.0	-1.2	-2.5	-1.8	-2.2	-2.1	-2.3	-1.3	-0.5	-2.2	-1.0	-2.1	-1.7	-1.8	-0.2
Hand grip strength (left)	2.1	5.6	11.2	-2.8	-2.4	-2.3	-1.9	-1.9	-2.3	-2.4	-3.3	-2.6	-2.2	-2.7	-1.4	-3.3	-1.6	-2.2	-1.2
Tinnitus: Yes, but not now, but have in the past	2.1	2.2	8.3	2.9	1.9	0.7	2.0	1.0	1.8	1.6	1.9	0.3	-0.5	1.9	0.9	1.6	1.2	-0.1	-0.3
Neck or shoulder pain in last month	2.1	3.0	6.5	-1.9	-2.1	-2.2	-2.6	-1.2	-1.6	-1.7	-2.2	-1.4	-1.3	-2.0	-0.5	-2.2	-0.9	-1.7	-0.1
Blood Eosinophil Count	2.0	15.2	30.5	4.6	4.4	3.9	3.7	3.4	4.6	4.2	5.5	3.0	3.2	5.2	2.6	4.5	3.2	2.5	1.8
Heel T-Score	2.0	15.8	30.0	-5.5	-5.2	-2.0	-5.2	-3.0	-5.0	-4.6	-5.4	-2.5	-0.3	-5.3	-1.4	-5.4	-3.2	-2.2	0.3
Medication: Simvastatin	2.0	2.9	5.6	1.3	1.7	1.8	1.6	1.6	1.4	1.7	1.5	2.4	1.8	1.5	1.8	2.0	1.4	1.6	2.0
Blood clot in the leg (DVT)	2.0	2.6	5.0	-2.0	-1.9	-0.7	-2.0	-1.7	-2.2	-1.8	-2.1	-0.8	0.7	-2.1	-0.3	-1.9	-1.5	-1.5	0.6
Osteoporosis (self-reported)	2.0	2.5	4.1	1.6	1.9	1.3	1.9	1.4	2.0	1.8	1.8	1.0	0.7	1.7	1.4	1.6	1.9	1.2	1.0
Asthma	1.9	3.7	6.0	2.2	1.6	2.0	2.4	1.7	1.7	1.7	2.2	2.2	2.4	1.9	1.6	2.2	1.1	2.1	1.5
Medication: Levothyroxine sodium	1.8	3.1	5.0	2.2	2.2	1.8	1.5	1.4	1.9	2.0	2.1	1.4	1.3	2.0	1.9	1.8	1.6	1.2	1.5
Medication: Aspirin	1.8	2.4	8.1	0.7	1.1	1.7	1.3	1.3	0.8	1.1	0.7	2.0	2.8	0.7	2.0	0.9	1.3	1.5	2.5
Alcohol drinker status: Never	1.8	2.1	4.8	-1.0	-1.4	-1.4	-1.1	-1.5	-1.5	-1.6	-1.1	-1.0	-1.2	-1.5	-2.2	-0.6	-2.0	-1.2	-1.9
Hair/balding pattern: Pattern 4	1.7	4.1	8.6	1.3	1.5	1.8	2.0	2.2	1.7	2.0	1.8	2.9	2.3	1.8	1.8	2.2	1.7	2.8	2.0
Medication: Ibuprofen	1.7	2.0	4.1	-1.0	-1.1	-1.0	-2.0	-1.7	-1.4	-1.6	-1.0	-1.6	-1.0	-1.2	-1.8	-1.2	-1.7	-1.3	-1.4
Overall health rating	1.7	3.6	8.4	-1.8	-1.9	-1.3	-2.9	-2.3	-2.4	-2.0	-2.2	-1.7	-0.3	-2.1	-0.8	-2.4	-1.6	-2.3	-0.0
Medication: Gliclazide	1.7	1.9	4.0	-1.5	-1.3	-1.1	-1.5	-1.6	-1.7	-1.4	-1.8	-1.5	-0.8	-1.6	-0.4	-2.0	-0.8	-1.5	-0.2
Type 2 Diabetes (T2D) (2018)	1.6	3.0	6.2	-0.8	-1.4	-2.2	-1.4	-1.7	-2.0	-1.6	-2.2	-2.0	-2.5	-1.8	-0.8	-2.1	-1.3	-1.8	-1.2
Qualifications: O levels/GCSEs or equivalent	1.6	2.5	6.3	-1.4	-2.1	-1.1	-2.5	-1.1	-1.8	-1.9	-1.5	-1.0	-1.2	-1.8	-1.6	-1.1	-2.1	-1.0	-1.2
Smoking status: Previous	1.6	2.4	6.2	1.0	1.5	1.7	2.5	1.3	1.6	1.5	1.8	1.5	1.8	1.7	1.0	1.6	1.1	1.4	1.2
Asthma (self-reported)	1.6	3.2	5.4	2.0	1.5	1.7	2.3	1.5	1.5	1.6	2.1	2.1	2.2	1.8	1.3	2.1	1.0	1.9	1.2
Medication: Paracetamol	1.6	2.5	5.7	-1.1	-0.8	-1.8	-1.7	-1.3	-1.2	-1.2	-1.2	-2.1	-2.4	-1.1	-2.1	-1.5	-1.2	-1.5	-2.2
Cholesterol lowering medication	1.6	2.4	3.7	1.1	1.6	1.5	1.7	1.7	1.2	1.7	1.2	1.9	1.5	1.2	1.7	1.6	1.7	1.4	1.8
Crohns Disease (2012)	1.5	2.4	5.6	-2.2	-2.2	-1.1	-1.7	-1.4	-1.9	-1.8	-2.2	-0.2	0.1	-2.4	-0.4	-1.8	-1.4	-0.7	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.8	3.5	1.4	1.9	1.3	1.6	1.1	1.7	1.6	1.5	0.9	0.2	1.7	0.5	1.5	1.4	1.4	-0.1
Medication: Aspirin	1.5	2.0	6.4	0.4	0.7	1.2	0.9	1.4	0.6	1.0	0.3	2.0	2.5	0.4	2.0	0.7	1.3	1.5	2.5
Hand grip strength (right)	1.4	3.7	7.5	-2.0	-1.9	-2.3	-1.5	-1.2	-1.7	-1.9	-2.7	-2.2	-2.5	-2.0	-1.2	-2.6	-1.2	-1.7	-1.2
Allergy	1.4	3.3	7.1	-1.4	-1.2	-2.2	-1.4	-1.8	-1.3	-1.5	-1.6	-2.5	-2.7	-1.3	-1.9	-1.8	-1.1	-2.3	-1.9
Time employed in main current job	1.4	1.6	3.0	-1.2	-1.7	-0.4	0.2	-1.3	-1.5	-1.4	-1.5	-1.1	-1.1	-1.5	-1.3	-1.1	-1.6	-1.0	-1.1
Mouth/teeth dental problems: Dentures	1.4	2.3	5.0	0.4	1.1	1.6	1.7	1.4	1.2	1.2	0.7	2.0	2.2	0.6	1.9	0.8	1.5	2.1	2.0
Number of self-reported non-cancer illnesses	1.4	2.4	10.0	0.1	0.3	2.3	0.9	1.2	0.1	0.6	0.3	2.3	3.2	0.1	1.8	0.7	0.6	2.1	2.6
Miserableness	1.4	2.4	3.9	1.9	1.9	1.6	1.2	1.7	1.7	1.6	1.4	1.2	1.0	1.5	2.0	1.2	1.7	1.4	1.4
Neuroticism (Nagel 2018)	1.3	3.0	5.2	-0.6	-1.4	-2.2	-1.8	-1.6	-1.4	-1.5	-1.3	-2.2	-1.9	-0.9	-2.3	-1.2	-1.9	-2.0	-2.2
Coronary Artery Disease (CAD)	1.3	1.6	3.1	1.3	1.3	1.5	0.9	1.3	1.8	1.6	1.4	0.8	0.9	1.5	1.1	1.2	1.6	0.8	0.7
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.0	5.6	-1.1	-1.4	-1.0	-2.0	-1.2	-1.4	-1.3	-1.6	-1.7	-1.3	-1.4	-0.6	-1.8	-1.0	-2.4	-0.4
Happiness	1.3	1.5	2.6	-1.0	-0.9	-1.1	-1.6	-1.3	-1.6	-1.2	-1.2	-1.4	-0.9	-1.0	-1.4	-1.2	-1.2	-1.3	-1.2
Noisy workplace	1.3	1.6	3.8	-1.1	-1.5	-0.1	-1.4	-2.0	-1.5	-1.6	-1.1	-0.9	0.3	-1.5	-0.9	-1.3	-1.6	-1.2	-0.4
Medication: Cholesterol lowering	1.3	2.0	6.9	0.1	0.6	1.7	0.7	1.3	0.9	0.9	0.4	1.9	2.5	0.5	2.1	0.6	1.1	1.4	2.6
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	7.3	-1.0	-1.3	-1.1	-2.7	-1.4	-1.1	-1.2	-1.2	-1.2	-0.6	-1.1	-0.9	-1.4	-1.1	-1.3	-0.6
Fractured/broken bones in last 5 years	1.3	1.6	4.6	1.4	1.3	1.1	2.1	1.0	1.3	1.3	1.5	1.3	0.7	1.4	0.9	1.5	1.2	1.0	0.7
Heart attack/myocardial infarction (self-reported)	1.3	1.6	6.9	0.4	0.2	1.7	0.0	1.0	0.7	0.8	0.4	1.2	2.4	0.5	2.3	0.3	1.0	0.5	2.6
Blood Red Count	1.2	11.1	31.0	1.3	2.1	4.1	2.8	3.3	2.4	2.6	2.7	4.7	5.6	2.2	3.4	3.2	2.7	2.8	4.6
Respiratory disease	1.2	2.6	4.8	1.9	1.4	1.2	2.2	1.1	1.6	1.6	2.1	1.8	1.9	1.8	1.1	2.1	0.9	1.4	1.0
Vitamin and mineral supplements	1.2	1.6	3.3	1.5	1.1	1.2	1.8	1.0	1.5	1.4	1.6	1.1	1.0	1.5	0.8	1.4	1.1	1.3	0.2
Heart attack	1.2	1.5	6.4	0.2	-0.1	1.6	-0.2	0.8	0.5	0.6	0.2	1.2	2.4	0.2	2.2	0.1	0.9	0.7	2.5
Heart disease (mother)	1.2	1.4	3.0	1.5	0.8	1.7	1.0	0.6	1.1	1.0	1.1	1.1	1.6	1.1	1.7	1.0	0.8	0.3	1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.6	6.3	2.5	1.8	-0.4	1.3	0.9	2.2	1.9	2.0	-0.2	-1.9	2.4	-0.1	1.8	1.6	0.6	-1.4
Eye problems/disorders: Glaucoma	1.2	1.4	7.2	-1.1	-0.7	1.3	0.1	0.4	-0.7	-0.4	-0.7	1.1	2.7	-1.1	1.2	-0.6	-0.1	1.2	2.1
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	3.1	-1.6	-1.4	-0.3	-1.6	-1.1	-1.8	-1.3	-1.8	-0.2	1.0	-1.7	0.1	-1.4	-1.0	-0.8	0.9
Other serious medical condition/disability diagnosed by doctor	1.1	1.5	3.4	-1.4	-1.3	-0.3	-1.8	-1.1	-1.5	-1.3	-1.6	-0.6	0.4	-1.7	0.0	-1.6	-1.0	-1.0	0.7
Ever used hormone-replacement therapy (HRT)	1.1	1.4	3.8	1.9	1.5	1.0	0.8	0.6	1.5	1.4	1.9	0.6	0.4	1.6	0.6	1.7	0.8	-0.2	0.3
Medication: Metformin	1.1	1.6	4.4	-0.0	-0.8	-1.6	-0.8	-1.4	-1.0	-0.9	-1.0	-1.8	-2.1	-0.8	-0.9	-1.1	-1.0	-1.9	-1.4
Fed-up feelings	1.1	1.9	5.0	-1.7	-1.6	-1.2	-1.4	-1.3	-1.5	-1.6	-1.9	-1.4	-0.4	-1.7	-0.2	-2.2	-0.9	-1.2	0.1
Stomach or abdominal pain in last month	1.1	1.4	2.9	-0.8	-1.2	-0.6	-1.7	-1.3	-0.9	-1.0	-0.9	-1.6	-1.3	-0.7	-1.4	-1.1	-1.1	-1.3	-1.4
Ever highly irritable/argumentative for 2 days	1.1	1.3	4.1	-1.1	-1.3	-1.0	-1.0	-1.4	-1.0	-1.1	-0.9	-1.6	-0.3	-0.9	-0.9	-1.4	-1.0	-2.0	-0.3
Supplements: Vitamin C	1.1	1.3	3.2	1.0	1.1	1.8	0.5	1.3	0.9	0.9	1.0	1.4	1.4	0.9	1.2	1.0	0.9	1.1	1.4
Medication for cholesterol	1.1	1.7	5.3	-1.9	-1.1	-2.2	-0.5	-0.2	-0.7	-0.9	-1.7	-1.2	-2.3	-1.1	-1.1	-1.6	-0.2	-0.3	-1.2
Illnesses of father: None of the above (group 1)	1.1	1.3	2.5	-1.1	-1.6	-1.0	-0.7	-1.4	-1.3	-1.4	-1.2	-0.8	-0.4	-1.3	-1.3	-0.9	-1.6	-0.9	-1.0
Irritability	1.1	1.8	4.5	-1.9	-1.6	-1.4	-1.6	-0.7	-1.7	-1.6	-1.8	-0.8	0.2	-1.6	-0.5	-2.1	-1.0	-0.5	0.1
Alzheimer’s Disease (in father)	1.0	1.1	3.2	-0.9	-0.8	-0.9	-1.8	-1.2	-1.1	-1.2	-0.6	-1.2	-0.5	-0.8	-1.2	-0.9	-1.2	-0.7	-0.9
Crohns Disease (2017)	1.0	2.3	6.5	-2.5	-2.1	-0.3	-1.9	-0.2	-1.5	-1.4	-2.3	0.4	0.7	-2.3	0.6	-1.7	-0.5	-0.5	1.5
Blood White Count	1.0	7.5	21.5	1.6	1.8	3.8	2.8	1.9	2.0	2.0	3.1	3.9	4.6	2.5	0.8	3.5	1.2	3.1	1.7
Relative age of first facial hair	1.0	2.0	4.3	1.8	1.3	1.6	2.1	0.8	1.6	1.4	2.0	1.1	1.2	1.7	0.3	2.0	0.6	0.8	0.0
Diabetes (self-reported)	1.0	1.6	4.7	-0.3	-0.9	-2.2	-0.3	-1.5	-1.1	-1.1	-1.2	-1.6	-1.7	-1.1	-0.6	-1.3	-1.1	-1.9	-0.8
Pulse rate	1.0	1.7	4.6	2.1	1.5	0.9	1.2	0.9	1.8	1.5	2.0	-0.2	-0.4	1.9	0.2	1.6	0.8	-0.5	-0.5
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	2.8	-0.8	-0.7	-0.7	-1.7	-1.5	-1.0	-1.2	-0.7	-1.4	-0.8	-0.8	-1.6	-0.9	-1.3	-1.5	-1.1
Lung cancer (father)	1.0	1.1	3.0	-0.4	-1.2	-0.2	-1.0	-1.7	-1.2	-1.2	-0.5	-1.0	-0.0	-0.9	-1.2	-0.6	-1.7	-1.3	-1.1
Illnesses of mother	1.0	1.2	4.2	-0.8	-1.0	-1.5	-0.4	-1.2	-1.0	-1.1	-0.2	-0.9	-0.9	-0.6	-2.0	-0.2	-1.6	-0.7	-1.7
Exposure to tobacco smoke at home	1.0	1.1	4.4	-0.5	-0.7	-0.7	-1.5	-1.4	-1.0	-1.0	-0.7	-1.3	-0.3	-0.8	-0.6	-0.9	-1.1	-2.1	-0.3
Glaucoma (self-reported)	1.0	1.2	4.1	-1.1	-0.2	1.5	0.5	0.9	-0.1	0.1	-0.4	1.1	2.0	-0.6	1.3	-0.4	0.5	1.9	1.8
Worry too long after embarrassment	1.0	1.7	6.0	-0.3	-1.0	-1.4	-1.3	-1.2	-0.6	-0.9	-0.6	-1.6	-1.9	-0.5	-1.9	-0.7	-1.3	-0.8	-2.4
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	2.7	0.4	0.9	1.4	0.3	1.1	0.8	0.8	0.6	1.2	1.2	0.6	1.4	0.6	1.0	1.6	1.4
High cholesterol (Self-reported)	1.0	1.8	6.2	-0.2	0.8	1.1	1.0	1.8	0.7	1.0	-0.1	1.8	1.4	0.2	2.1	0.3	1.6	1.5	2.5
Depression (Nagel 2018)	0.9	1.3	2.3	-0.8	-1.2	-1.0	-1.4	-1.3	-1.4	-1.3	-1.3	-1.1	-0.1	-1.5	-0.2	-1.4	-1.2	-1.5	0.1
Alzheimer’s Disease (in mother)	0.9	1.1	2.9	1.2	0.8	0.6	0.5	1.2	1.4	1.4	0.7	0.5	-0.3	1.1	1.7	0.3	1.7	0.8	0.8
Serious illness, injury or assault to yourself	0.9	1.1	2.7	-1.6	-1.1	-0.4	-0.7	-0.6	-1.2	-1.1	-1.6	-0.1	0.6	-1.7	0.4	-1.5	-0.4	-0.7	1.3
Father’s age at death	0.9	1.2	2.5	-0.5	-0.8	-1.4	-1.3	-1.0	-0.8	-1.1	-0.9	-1.4	-1.6	-0.8	-1.2	-0.9	-1.0	-1.1	-1.6
Migraine (self-reported)	0.9	1.1	3.5	-0.9	-0.5	-1.7	0.2	-0.7	-0.7	-0.7	-1.0	-1.2	-1.9	-0.8	-1.4	-0.8	-0.6	-0.4	-1.7
Knee pain experienced in last month	0.9	1.4	3.8	-1.6	-1.4	-0.1	-1.9	-0.8	-1.5	-1.3	-1.6	-0.7	0.1	-1.5	0.0	-1.8	-0.6	-0.8	0.6
Hearing aid user	0.9	1.1	3.5	-0.4	0.7	-0.5	1.3	1.9	1.0	1.0	-0.0	1.0	-0.1	0.5	1.0	0.1	1.7	1.7	1.0
Intelligence (Savage-Jansen 2018)	0.8	2.6	4.9	1.6	2.0	1.3	0.9	2.1	1.9	2.1	1.4	1.3	-0.4	1.7	1.4	1.7	2.2	1.8	0.6
Body Mass Index (BMI) (2010)	0.8	1.1	2.8	0.1	0.8	0.5	0.3	1.6	0.7	0.9	0.2	1.0	0.5	0.7	1.7	0.1	1.7	1.5	1.7
Systolic Blood Pressure	0.8	4.1	12.1	-3.2	-2.1	-2.4	-1.9	-0.4	-2.4	-1.6	-3.5	-0.5	-0.1	-2.6	0.9	-3.3	0.1	-0.2	1.6
Systolic blood pressure, automated reading	0.8	2.2	7.9	-2.1	-1.1	-2.8	-0.9	-0.6	-1.7	-1.1	-2.4	-0.8	-1.0	-1.6	0.3	-2.4	0.1	-0.6	0.5
Medication: Ramipril	0.8	1.1	5.0	-0.1	0.2	1.8	0.1	0.6	-0.1	0.4	0.2	1.5	2.2	0.1	1.2	0.4	0.6	0.8	1.9
Wheeze or whistling in the chest in last year	0.8	1.5	7.0	-0.5	0.1	1.2	1.1	1.1	0.3	0.5	-0.3	1.4	2.0	-0.1	1.9	-0.2	1.0	1.2	2.6
Number of children fathered	0.8	0.9	5.7	2.4	0.6	0.0	0.7	-0.6	0.5	0.4	1.2	-0.4	-0.8	1.0	-0.6	1.3	-0.5	-0.4	-1.5
Number of full sisters	0.8	1.0	2.0	0.8	1.2	0.9	1.2	0.7	1.0	1.0	0.8	0.8	0.8	0.8	1.4	0.5	1.1	1.1	1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	3.4	-0.6	-0.2	1.4	0.7	0.9	-0.2	0.2	-0.4	1.4	1.9	-0.2	1.1	0.0	0.4	1.4	1.7
Long-standing illness, disability or infirmity	0.8	1.2	3.0	-1.2	-1.1	0.3	-1.1	-0.8	-1.1	-0.9	-1.1	0.5	1.7	-1.5	0.6	-1.0	-0.8	-0.5	1.7
Ever had bowel cancer screening	0.8	1.0	2.3	0.8	1.1	1.2	0.8	1.2	1.1	1.1	1.2	0.9	0.5	1.3	0.4	1.5	0.8	0.0	0.5
Medication: Blood pressure	0.8	1.5	6.3	1.0	0.6	2.3	0.8	0.6	0.3	0.7	1.0	1.6	2.5	0.6	1.0	1.2	0.2	1.2	1.4
Ever had prostate specific antigen (PSA) test	0.8	0.9	3.0	0.6	0.4	0.9	0.8	1.4	0.7	0.6	0.4	1.7	1.2	0.6	1.1	0.9	0.7	1.4	1.2
Worry (Nagel 2018)	0.7	1.5	4.9	-0.3	-0.7	-2.0	-0.8	-0.6	-0.5	-0.7	-0.5	-1.6	-1.9	-0.3	-2.1	-0.5	-1.1	-1.2	-2.2
Irritable Bowel Disease (IBD)	0.7	1.7	5.1	-2.3	-1.7	0.3	-1.7	0.3	-1.2	-1.0	-1.9	0.9	1.2	-1.8	0.8	-1.1	-0.1	0.2	1.9
Hayfever, allergic rhinitis or eczema	0.7	1.5	3.5	0.9	0.9	1.3	0.9	1.4	1.0	1.2	1.3	1.7	1.4	1.1	1.1	1.4	1.0	1.9	1.0
Chronic bronchitis/emphysema (father)	0.7	0.8	2.2	0.8	1.1	0.5	1.5	0.9	1.4	1.1	0.9	-0.0	-0.1	1.3	0.5	0.6	1.3	0.2	0.0
Hair/balding pattern: Pattern 2	0.7	0.9	3.1	-0.7	-0.6	-1.4	-0.8	-1.1	-0.8	-0.7	-1.0	-1.1	-1.0	-0.9	-0.2	-1.1	-0.3	-1.8	-0.2
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	5.8	0.4	-0.1	-1.2	-0.6	-0.4	-0.2	-0.4	-0.1	-1.3	-2.4	-0.1	-1.3	-0.2	-0.6	-0.8	-2.2
Medication: Amlodipine	0.7	1.0	2.1	0.8	1.1	1.1	0.4	0.7	0.7	0.9	0.9	1.2	1.3	0.9	1.3	0.7	1.1	1.3	1.4
Exposure to tobacco smoke outside home	0.7	1.0	3.1	-0.1	-0.9	-0.2	-1.0	-1.8	-1.0	-0.9	-0.3	-0.9	-0.4	-0.8	-1.1	-0.5	-1.5	-1.4	-1.2
Health satisfaction	0.7	0.9	2.6	-0.5	-0.8	-0.1	-1.6	-1.1	-1.4	-0.9	-1.1	-0.9	-0.1	-1.0	-0.3	-1.1	-0.8	-1.1	-0.0
Mineral and other dietary supplements	0.7	0.9	2.7	0.2	0.5	0.8	0.8	1.1	0.7	0.7	0.4	1.1	1.5	0.4	1.3	0.3	0.9	1.6	1.3
Mother’s age at death	0.7	0.8	2.5	-0.9	-0.6	-1.6	-0.7	-0.3	-0.6	-0.7	-0.9	-1.3	-1.3	-0.7	-0.8	-1.2	-0.4	-0.9	-0.8
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	4.6	-0.9	-0.3	1.1	-0.3	0.7	-0.3	-0.0	-0.7	0.8	1.7	-0.5	1.4	-0.7	0.6	0.4	2.2
Schizophrenia vs Biploar Disorder	0.6	0.8	2.2	-0.1	-0.5	-0.7	-0.9	-1.2	-0.8	-0.7	-0.4	-1.5	-0.8	-0.3	-0.9	-0.9	-0.9	-1.1	-1.2
Major Depression (MDD)	0.6	0.7	2.4	-0.0	-0.4	-1.0	-0.9	-1.5	-0.6	-0.7	0.0	-1.2	-0.2	-0.3	-0.9	-0.4	-1.0	-1.6	-1.0
Reaction Time	0.6	1.2	4.2	1.1	0.9	-1.2	0.0	-0.6	0.9	0.7	1.1	-1.2	-2.0	1.3	-1.0	0.7	0.4	-0.5	-2.1
Lupus	0.6	0.8	2.2	-1.2	-1.3	0.1	-0.4	-0.7	-1.1	-1.2	-0.7	0.3	1.2	-1.2	-1.0	-0.4	-1.5	-0.1	-0.3
Waist Hip Ratio (WHR)	0.6	2.8	7.0	0.4	0.8	2.4	2.5	1.4	1.2	1.2	0.7	2.1	2.6	0.8	1.8	0.9	1.4	2.2	1.9
Frequency of depressed mood in last 2 weeks	0.6	0.8	1.8	-0.4	-0.4	-1.3	-0.9	-0.9	-0.8	-0.6	-1.0	-1.3	-1.1	-0.8	-0.1	-1.3	-0.3	-1.2	-0.3
Supplements: Zinc	0.6	0.7	2.6	0.2	0.2	-0.6	-0.5	-0.4	-0.3	-0.2	0.2	-1.0	-1.6	0.3	-1.5	0.1	-0.6	-1.0	-1.6
Supplements: Glucosamine	0.6	0.8	2.7	-0.3	-0.8	-0.8	-1.0	-0.7	-0.8	-0.7	-0.7	-0.9	-1.6	-0.6	-0.9	-0.6	-0.7	-1.0	-1.2
Impedance of arm (left)	0.6	3.0	5.8	1.3	1.2	1.6	1.6	1.8	2.0	1.9	2.1	2.2	1.6	1.8	0.9	2.4	1.4	2.3	1.0
Tense / ‘highly strung’	0.6	1.0	4.0	0.4	-0.2	-1.9	-0.1	-0.3	0.0	-0.1	-0.2	-1.5	-2.0	0.3	-1.0	-0.4	-0.2	-1.3	-1.5
Comparative body size at age 10	0.6	1.6	4.6	-1.4	-1.4	-0.5	-2.1	-0.4	-1.4	-1.0	-2.1	-0.6	-0.7	-1.5	1.0	-2.0	0.0	-0.3	1.1
Age at first live birth	0.6	1.0	2.3	-1.5	-1.0	-0.9	-1.1	-0.4	-0.7	-1.0	-1.1	-1.2	-1.1	-1.0	-1.1	-1.0	-0.8	-1.1	-0.6
Mean time to correctly identify matches	0.6	1.2	4.6	1.1	1.0	-1.0	0.6	-0.7	1.0	0.7	1.2	-1.0	-1.6	1.4	-1.2	0.9	0.3	-0.3	-2.1
Pulse rate, automated reading	0.6	1.9	4.9	2.2	1.9	0.9	0.9	0.9	2.1	1.5	2.1	0.2	-0.1	2.0	0.3	1.8	0.9	-0.9	-0.1
Diabetes diagnosed by doctor	0.6	0.9	3.5	0.0	-0.5	-1.5	0.1	-1.2	-0.9	-0.8	-0.9	-1.3	-0.9	-0.8	0.0	-1.1	-0.8	-1.9	-0.2
Breast cancer (self-reported)	0.6	0.7	2.5	-0.8	-0.8	-0.2	-0.7	-0.5	-0.8	-0.6	-0.9	0.3	1.2	-1.1	1.0	-0.9	-0.2	-0.1	1.6
Guilty feelings	0.6	0.9	6.2	0.8	0.1	-1.5	-0.5	0.0	-0.1	-0.2	-0.1	-1.2	-2.5	0.2	-0.9	-0.1	-0.3	-0.8	-1.5
Fasting Glucose	0.5	0.6	2.2	-1.1	-0.2	-0.7	-0.6	0.0	-1.0	-0.3	-1.5	0.4	0.3	-0.7	0.9	-0.6	0.1	0.6	1.4
Neuroticism (2016)	0.5	0.7	2.9	0.4	-0.8	-0.5	-0.7	-0.7	-0.4	-0.7	-0.3	-0.9	-0.8	0.1	-1.5	0.0	-1.0	0.0	-1.7
Chronotype (morning person)	0.5	1.1	3.5	-1.2	-1.6	-0.3	-0.4	-0.7	-1.5	-1.1	-0.9	1.0	1.9	-1.3	-0.0	-0.5	-1.2	0.7	0.9
Ever had hysterectomy (womb removed)	0.5	0.6	1.5	-1.0	-1.2	-0.8	-0.2	-0.2	-1.0	-0.9	-1.2	-0.3	0.1	-1.2	-0.2	-1.0	-0.6	-0.5	0.1
Diabetes (mother)	0.5	0.6	1.8	-0.6	-0.5	-0.9	-0.5	-0.1	-0.3	-0.2	-1.3	-0.7	-1.1	-0.7	0.8	-1.3	0.6	-0.9	0.7
Current tobacco smoking	0.5	0.7	2.4	1.0	1.1	1.1	0.1	0.6	0.7	0.8	0.5	0.5	0.8	0.6	1.5	0.3	1.0	0.0	1.4
Qualifications: CSEs or equivalent	0.5	0.7	3.1	-0.5	-0.9	-0.8	-0.4	-0.2	-0.6	-0.6	-0.8	-0.5	-1.8	-0.7	-1.0	-0.5	-0.7	0.3	-1.6
Medication: Atenolol	0.5	0.6	3.0	0.8	0.6	0.7	1.1	0.2	0.1	0.5	0.5	0.8	1.7	0.3	1.1	0.6	0.2	-0.1	1.2
Number of incorrect matches in round	0.5	0.8	3.3	0.7	0.7	-0.7	0.4	-0.1	1.0	0.8	0.4	-1.4	-1.8	0.8	-0.5	0.1	0.9	-1.2	-1.0
Nervous feelings	0.5	0.9	4.0	-0.2	-0.6	-2.0	-0.2	0.2	-0.4	-0.4	-0.7	-0.9	-1.6	-0.3	-1.4	-0.4	-0.5	-0.3	-1.6
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	2.7	-1.0	-0.9	-0.8	-1.1	-0.7	-0.8	-0.8	-0.9	-0.9	-0.4	-0.9	-0.5	-1.1	-0.6	-1.6	0.1
Had menopause	0.5	0.6	2.9	-0.7	-0.5	-1.0	-0.1	-0.6	-0.6	-0.6	-1.0	-1.0	-0.7	-0.9	-0.0	-1.1	-0.3	-1.7	0.0
Mouth/teeth dental problems	0.5	0.7	2.6	1.2	0.9	0.3	1.6	0.8	0.8	0.8	1.1	0.4	-0.4	1.1	0.2	1.1	0.5	0.6	-0.4
Impedance of arm (right)	0.5	2.3	4.9	0.9	1.1	1.4	1.3	1.6	1.8	1.5	1.8	2.0	1.7	1.4	0.5	2.2	1.0	2.0	0.7
Hip circumference	0.5	2.0	3.3	-1.1	-1.0	-1.7	-1.5	-1.4	-1.7	-1.4	-1.7	-1.5	-1.7	-1.4	-0.5	-1.8	-1.0	-1.8	-0.7
Medication: Omeprazole	0.5	0.6	1.9	-1.4	-0.9	0.1	-0.6	-0.0	-0.8	-0.6	-1.1	0.1	0.6	-0.9	0.4	-1.0	-0.1	-0.4	1.3
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.6	-0.1	0.0	-1.4	-0.6	-0.3	-0.4	-0.4	-0.5	-1.2	-1.0	-0.4	-0.6	-0.8	-0.5	-1.6	-0.6
Mood swings	0.5	0.8	2.2	-0.3	-0.5	-1.0	-1.2	-0.8	-0.9	-0.7	-0.9	-1.3	-1.3	-0.6	-0.4	-1.1	-0.6	-1.5	-0.5
Ulcerative Colitis (UC)	0.4	0.8	2.6	-1.1	-0.5	0.9	-1.0	0.7	-0.4	-0.1	-0.6	1.4	1.4	-0.5	0.7	0.1	0.3	0.8	1.6
Ovarian Cancer	0.4	0.6	2.5	-0.3	-0.1	-0.9	-0.9	-0.2	-0.4	-0.3	-0.4	-1.0	-1.6	-0.2	-0.8	-0.4	-0.4	-1.2	-1.0
HbA1C	0.4	0.5	1.9	0.8	0.2	-0.6	-0.4	-0.3	-0.4	-0.3	-0.2	-0.8	-1.4	0.7	-0.8	0.4	-0.3	-0.6	-1.4
Type 2 Diabetes (T2D) (2012)	0.4	0.4	1.1	-0.6	-0.1	-0.3	-0.7	0.8	-0.5	0.1	-0.9	0.5	-0.3	-0.4	1.0	-0.7	0.9	0.8	1.0
Ulcerative Colitis	0.4	0.6	1.1	-0.8	-1.0	-0.3	-0.9	-0.8	-1.0	-0.8	-0.8	-0.2	-0.2	-0.8	-1.0	-0.4	-1.0	-0.5	-0.6
Smoking Status	0.4	1.0	2.9	0.8	1.0	0.9	1.3	0.6	0.8	0.9	0.9	0.7	1.7	0.9	1.4	0.4	0.8	0.1	1.6
Medication for hormone replacement therapy	0.4	0.5	2.2	1.5	0.9	0.5	-0.2	-0.3	0.7	0.5	1.2	-0.0	0.1	0.8	0.3	0.8	-0.2	-0.5	-0.2
Diabetes (father)	0.4	0.5	1.3	1.0	0.9	0.1	0.6	0.5	0.7	0.9	0.5	0.3	-0.2	0.7	1.1	0.4	1.1	0.3	0.4
Multivitamins +/- minerals	0.4	0.6	1.1	-0.7	-0.6	-0.8	-0.7	-0.7	-1.0	-0.8	-0.9	-0.7	-0.9	-0.9	-0.2	-0.8	-0.7	-1.0	-0.1
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.4	0.4	0.8	0.4	0.2	0.6	0.7	0.8	0.4	0.5	0.4	0.5	1.2	0.1	1.0	1.1	1.0
High blood pressure (mother)	0.4	0.5	1.2	-0.7	-0.7	0.1	-1.1	-0.6	-0.8	-0.8	-1.1	-0.4	-0.1	-1.0	0.2	-1.1	-0.5	-0.7	0.3
Financial difficulties in last 2 years	0.4	0.6	1.4	-0.7	-0.4	-1.2	-0.5	-0.6	-0.6	-0.5	-1.0	-0.8	-0.6	-0.9	0.1	-1.2	-0.1	-1.1	0.1
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	3.0	0.0	-0.3	0.9	0.0	0.1	-0.2	-0.3	0.3	1.2	1.7	-0.2	0.3	0.4	-0.6	0.8	0.8
Trunk fat-free mass	0.4	2.1	5.1	-1.8	-1.3	-0.6	-1.0	-0.8	-2.2	-1.8	-2.2	-0.8	-0.8	-2.1	-0.6	-2.0	-1.4	-0.7	-0.4
Worrier / anxious feelings	0.4	0.8	3.8	1.2	0.2	-0.2	0.1	-0.2	0.5	0.3	1.0	-0.9	-1.4	1.0	-1.4	0.8	-0.4	-0.4	-2.0
Trunk predicted mass	0.4	2.1	5.2	-1.8	-1.3	-0.7	-1.0	-0.8	-2.2	-1.8	-2.3	-0.8	-0.8	-2.1	-0.7	-2.0	-1.4	-0.7	-0.4
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.1	-0.9	-0.8	-0.3	-1.0	-1.0	-0.4	-0.5	-0.5	-0.9	0.7	-0.6	-0.4	-0.9	-0.6	-0.3	-0.0
Medication: Blood pressure	0.4	0.7	3.7	-0.8	-0.1	0.5	0.1	0.0	-0.3	-0.0	-0.5	0.8	1.8	-0.3	1.2	-0.5	0.5	0.5	1.9
Chest pain or discomfort	0.4	0.6	1.6	-1.0	-1.0	-0.3	-0.4	-0.4	-0.8	-0.5	-1.0	-0.8	0.5	-0.9	0.1	-1.3	-0.2	-0.9	0.5
Had major operations	0.4	0.5	0.8	-0.9	-0.7	-0.4	-0.5	-0.4	-0.6	-0.7	-0.9	-0.4	-0.4	-0.8	-0.9	-0.6	-0.8	-0.5	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.8	0.6	0.7	0.8	1.4	1.0	0.4	0.5	0.5	0.9	-0.1	0.6	0.2	0.8	0.4	1.1	-0.0
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.0	-0.7	-1.0	-0.1	1.0	0.2	-0.4	-0.4	-0.7	0.9	0.8	-0.7	0.4	-0.2	-0.1	0.9	0.7
Eye problems/disorders: Cataract	0.4	0.4	1.5	-0.2	-0.7	0.2	-0.2	-1.1	-0.5	-0.7	-0.2	-0.4	-0.3	-0.6	-1.1	-0.0	-1.2	-0.5	-1.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	2.0	-0.9	-1.1	-0.9	-1.4	-0.7	-0.7	-0.9	-0.4	-0.9	-0.4	-0.5	-1.0	-0.7	-0.8	-0.8	-0.6
Smoking status: Current	0.4	0.6	1.9	1.0	1.1	0.7	0.0	0.4	0.6	0.7	0.5	0.4	0.8	0.6	1.4	0.3	0.8	-0.1	1.3
Average weekly champagne plus white wine intake	0.4	0.5	1.8	0.1	-0.4	0.2	-0.3	-1.0	-0.2	-0.4	0.4	-0.8	-0.5	0.1	-1.2	0.3	-0.9	-1.4	-1.1
Medication: Atorvastatin	0.4	0.5	2.6	-0.1	-0.0	0.4	-0.2	0.2	0.2	0.1	-0.3	0.1	1.5	-0.2	1.3	-0.5	0.4	-0.2	1.6
Diastolic blood pressure, automated reading	0.4	1.1	2.9	-1.3	-0.8	-1.7	-0.6	-0.9	-1.2	-1.1	-1.4	-0.8	-0.4	-1.2	-0.4	-1.4	-0.7	-1.2	-0.1
Vascular/heart problems diagnosed by doctor	0.4	1.1	7.0	0.3	0.1	-1.5	-0.4	-0.1	0.2	-0.2	0.1	-1.1	-2.6	0.1	-1.4	0.1	-0.4	-0.1	-2.3
Supplements: Calcium	0.4	0.4	1.3	0.9	0.3	-0.5	-0.2	-0.6	0.3	0.0	0.5	-0.5	-0.9	0.4	-0.9	0.6	-0.5	-0.9	-1.1
Impedance of whole body	0.4	2.2	4.5	1.3	1.2	0.5	1.6	1.4	2.1	1.6	2.0	1.5	1.3	1.7	0.5	2.1	1.1	1.6	0.5
Bipolar Disorder or Schizophrenia	0.3	0.7	2.0	-0.9	-1.4	-0.8	0.1	-0.6	-1.0	-0.9	-0.7	-0.1	-0.5	-0.8	-1.3	-0.3	-1.2	0.0	-1.0
Schizophrenia (2018)	0.3	0.5	1.4	-0.7	-1.2	-0.5	-0.3	-0.7	-0.9	-0.8	-0.7	-0.4	-0.6	-0.7	-1.0	-0.5	-1.0	-0.3	-0.9
Verbal and Numeric Reasoning (VNR)	0.3	0.8	1.6	1.0	1.0	1.0	0.4	1.3	0.9	1.1	0.8	0.9	-0.3	0.9	0.5	1.2	0.9	1.0	0.1
LDL Cholesterol	0.3	0.5	1.7	0.3	0.5	0.2	0.8	0.8	0.2	0.4	0.3	1.3	0.7	0.1	0.9	0.7	0.5	0.9	1.1
Primary Biliary Cirrhosis	0.3	0.5	1.4	1.2	1.0	0.7	0.2	0.4	0.8	0.9	0.8	0.0	-0.5	0.8	0.4	0.7	0.6	0.6	-0.4
Cardiovascular Disease	0.3	0.9	4.0	-0.6	-0.3	1.2	0.2	0.4	-0.4	0.2	-0.5	1.0	1.8	-0.1	1.3	-0.3	0.6	1.0	2.0
Lung FEV1/FVC ratio	0.3	1.7	5.2	2.1	0.6	-1.0	-0.1	-1.1	0.3	0.0	1.6	-1.0	-1.5	1.4	-1.6	1.3	-1.2	-1.4	-2.3
Hair Pigment	0.3	9.5	15.8	-3.4	-4.0	-3.0	-2.4	-3.5	-3.6	-3.7	-3.4	-2.3	-1.1	-3.9	-2.5	-3.3	-3.7	-2.3	-1.6
Sensitivity / hurt feelings	0.3	0.5	1.9	1.4	0.4	0.3	0.5	-0.1	0.8	0.6	1.0	0.0	0.1	1.1	-0.3	1.0	-0.1	0.1	-0.9
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.6	-0.5	-0.7	-0.7	-0.2	-0.6	-0.6	-0.6	-0.5	-0.3	0.3	-0.6	-0.5	-0.4	-0.8	-0.6	-0.2
Severe depression (siblings)	0.3	0.4	1.5	-0.3	-0.6	-1.0	0.0	-0.6	-0.8	-0.7	-0.5	-0.6	-0.3	-0.5	-0.3	-0.6	-0.7	-1.2	0.2
Sitting height	0.3	1.8	4.3	-2.1	-1.9	-0.5	-1.0	-0.2	-2.0	-1.8	-1.8	-0.1	-0.1	-2.0	-1.2	-1.2	-1.7	-0.2	-0.4
Impedance of leg (left)	0.3	1.4	4.0	1.3	1.2	-0.5	1.4	1.0	2.0	1.4	1.7	0.7	0.7	1.6	0.2	1.6	0.9	0.7	0.1
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.5	-0.2	-0.5	-0.7	-0.5	-0.6	-0.4	-0.3	-0.6	-1.2	-1.1	-0.3	-0.0	-1.1	0.1	-0.6	-0.4
Pulse wave reflection index	0.3	0.3	1.2	-0.4	-0.1	0.4	0.8	0.3	0.2	-0.1	-0.0	1.1	1.1	-0.1	0.5	0.2	0.1	1.0	0.8
Loud music exposure frequency	0.3	0.3	1.0	0.3	0.6	0.6	-0.1	0.5	0.4	0.5	0.4	-0.1	0.8	0.4	1.0	-0.2	0.7	0.1	0.9
Birth weight	0.3	0.6	3.2	0.5	0.2	-0.7	0.0	-0.6	-0.2	-0.3	0.0	-0.9	-1.5	-0.1	-1.3	0.1	-0.8	-0.5	-1.8
High blood pressure (siblings)	0.3	0.5	0.9	1.0	0.9	0.5	0.8	0.1	0.6	0.7	0.9	0.3	0.4	0.7	0.6	0.8	0.5	-0.6	0.8
Arm fat-free mass (right)	0.3	1.4	3.4	-1.2	-0.9	-0.7	-0.7	-0.7	-1.7	-1.4	-1.8	-1.1	-1.2	-1.5	-0.3	-1.8	-0.9	-1.1	-0.4
Pulse wave peak to peak time	0.3	0.4	1.6	-0.3	-0.1	0.4	-0.6	1.1	0.3	0.4	0.0	0.6	0.6	0.3	0.8	-0.1	0.7	1.3	0.9
Emphysema/chronic bronchitis	0.3	0.4	1.4	0.6	0.7	0.8	0.7	0.3	0.5	0.5	0.3	-0.1	0.6	0.4	1.2	-0.2	0.7	-0.1	1.0
Medication: Seretide 50 evohaler	0.3	0.4	1.1	0.3	-0.6	-0.6	-0.9	-0.3	-0.3	-0.2	-0.5	-0.8	-0.8	-0.1	0.7	-1.1	0.5	-0.7	0.1
Suffer from ‘nerves’	0.3	0.5	3.2	-0.1	-0.1	-1.2	0.4	0.3	-0.1	-0.1	-0.7	-0.7	-1.8	-0.3	-0.7	-0.3	-0.0	-0.3	-1.1
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	2.0	-0.2	-0.3	0.9	-1.4	-0.1	-0.0	-0.3	0.3	-0.4	-0.2	0.2	-1.3	0.2	-0.6	0.1	-1.2
Hypertension (Self-reported)	0.3	0.7	3.5	-0.2	0.2	1.2	0.6	0.3	-0.0	0.4	0.1	1.0	1.9	0.2	1.0	0.1	0.6	0.6	1.7
Illnesses of siblings: Diabetes	0.3	0.3	1.2	0.0	0.7	0.4	0.4	0.7	0.3	0.7	-0.0	-0.2	-0.2	0.1	1.1	-0.3	1.1	0.3	0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	2.1	-1.5	-0.8	-0.2	0.0	1.0	-0.7	-0.4	-1.3	0.6	0.3	-1.0	0.6	-0.9	0.2	0.7	1.1
Commuting to job workplace: Walk	0.3	0.3	0.8	0.8	0.9	0.8	0.0	-0.1	0.4	0.5	0.8	0.4	0.7	0.6	-0.2	0.9	-0.2	0.2	-0.1
Wears glasses or contact lenses	0.3	0.4	3.0	0.1	0.2	1.2	0.7	-0.2	0.2	0.3	0.6	0.5	1.7	0.3	0.1	0.4	-0.0	0.1	0.4
Ever taken oral contraceptive pill	0.3	0.3	1.1	0.9	0.5	0.4	0.1	0.4	0.4	0.6	1.0	0.1	0.4	1.0	0.4	0.7	0.4	-0.1	0.5
Illnesses of father: High blood pressure	0.3	0.3	0.9	-0.5	-0.1	-0.8	-0.0	0.5	-0.2	-0.1	-0.8	0.1	-0.6	-0.6	0.9	-0.9	0.5	0.4	0.9
Arm fat-free mass (left)	0.3	1.3	2.9	-1.1	-0.7	-0.8	-0.8	-0.8	-1.6	-1.3	-1.7	-1.1	-1.1	-1.4	-0.4	-1.7	-0.9	-1.1	-0.4
Average weekly beer plus cider intake	0.3	0.4	0.8	0.7	0.5	0.5	0.7	0.8	0.6	0.7	0.6	0.5	-0.1	0.8	0.8	0.5	0.9	0.5	0.6
Ever depressed for a whole week	0.3	0.3	0.7	0.9	0.5	0.2	0.6	0.7	0.8	0.7	0.5	-0.4	-0.7	0.8	0.6	0.1	0.8	-0.1	0.0
Basal cell carcinoma (self-reported)	0.3	0.3	1.1	-1.1	-0.3	-0.4	-0.2	-0.0	-0.7	-0.6	-0.9	-0.2	-0.3	-0.8	-0.6	-0.7	-0.4	0.4	-0.4
Alcohol drinker status: Previous	0.3	0.3	1.7	0.8	0.1	-0.9	0.3	-0.0	0.4	0.4	0.3	-0.2	-1.3	0.5	0.1	0.2	0.4	-0.7	-0.6
Arm predicted mass (left)	0.3	1.5	3.5	-1.3	-0.9	-0.8	-0.8	-0.9	-1.8	-1.5	-1.9	-1.1	-1.1	-1.6	-0.4	-1.8	-1.1	-1.2	-0.4
Bipolar Disorder (2018)	0.2	0.3	0.9	-0.6	-0.8	-0.5	0.4	-0.1	-0.4	-0.5	-0.3	0.4	-0.1	-0.4	-0.9	0.2	-0.7	0.4	-0.4
Prostate Cancer	0.2	0.3	0.8	0.8	0.6	-0.1	0.6	0.5	0.8	0.3	0.9	0.1	-0.2	0.7	0.2	0.6	0.1	-0.6	-0.0
Mean Putamen Volume	0.2	0.2	0.7	0.1	0.7	-0.2	0.2	-0.0	0.4	0.2	0.6	-0.4	-0.2	0.6	-0.6	0.5	0.0	-0.2	-0.8
Triglycerides	0.2	0.4	1.4	0.3	0.5	0.2	-0.4	0.6	0.1	0.6	-0.0	0.4	0.0	0.2	1.2	-0.0	1.0	1.0	1.0
Lung FVC	0.2	0.9	2.7	-0.7	-0.9	-1.1	-1.0	-0.8	-0.2	-0.6	-0.3	-1.6	-1.1	-0.2	-1.6	-0.6	-0.4	-0.9	-1.4
Number of treatments/medications taken	0.2	0.3	2.5	0.2	0.1	1.0	-0.4	-0.2	-0.2	0.0	0.3	0.6	1.6	0.1	0.2	0.4	-0.3	0.2	0.8
Hearing difficulty/problems: Yes	0.2	0.3	1.3	0.6	1.1	0.3	-0.1	0.4	0.5	0.9	0.4	0.1	0.1	0.7	0.7	0.1	1.0	0.2	0.5
Trunk fat percentage	0.2	0.8	2.2	1.0	0.9	1.0	0.9	0.6	0.8	0.9	0.8	0.5	0.5	1.1	1.5	0.5	1.1	0.1	1.0
Taking other prescription medications	0.2	0.3	1.0	-0.1	-0.4	-0.3	-1.0	-0.5	-0.5	-0.5	-0.5	-0.3	0.7	-0.6	0.4	-0.8	-0.5	-0.6	0.6
Age when periods started (menarche)	0.2	0.4	1.8	-1.3	-0.5	-0.4	-0.4	0.4	-0.3	-0.1	-0.7	0.6	-0.2	-0.8	-0.7	-0.0	0.1	1.4	-0.5
High blood pressure	0.2	0.7	3.2	-0.0	0.2	1.3	0.6	0.2	0.0	0.4	0.1	0.8	1.8	0.2	1.1	0.1	0.5	0.2	1.7
Alcohol usually taken with meals	0.2	0.3	1.4	-0.2	-0.1	-0.4	0.4	0.4	-0.3	-0.1	-0.1	-0.2	-0.9	-0.0	-1.2	0.5	-0.4	-0.4	-1.0
Prospective memory result	0.2	0.2	1.0	-1.0	-0.4	0.6	-0.5	0.1	-0.2	-0.0	-0.4	0.2	0.4	-0.2	0.3	-0.4	0.3	0.3	0.7
Pulse wave Arterial Stiffness index	0.2	0.3	1.1	0.2	0.1	-0.3	0.7	-0.8	-0.3	-0.3	-0.1	-0.3	-0.5	-0.3	-0.6	0.1	-0.5	-1.1	-0.7
Breastfed as a baby	0.2	0.2	0.9	0.1	0.2	0.7	0.5	-0.5	-0.4	-0.4	0.0	-0.2	-0.1	-0.2	-0.9	0.1	-0.6	0.2	-1.0
Gout (self-reported)	0.2	0.3	1.0	-0.3	0.0	-0.3	-0.6	-0.6	-0.5	-0.4	-0.7	-0.7	-0.6	-0.5	0.4	-1.0	0.0	-0.7	0.2
Eye problems/disorders: None of the above	0.2	0.2	0.6	-0.4	-0.1	-0.1	-0.6	0.3	0.1	0.0	-0.4	-0.3	-0.6	0.1	0.5	-0.6	0.8	-0.2	0.5
Medication: Allopurinol	0.2	0.2	1.2	-0.1	-0.1	-0.5	-0.4	-0.8	-0.4	-0.3	-0.4	-0.4	-0.1	-0.3	0.4	-0.7	0.0	-1.1	0.5
Arm predicted mass (right)	0.2	1.1	2.9	-1.0	-0.7	-0.6	-0.5	-0.5	-1.5	-1.2	-1.7	-1.0	-1.3	-1.3	-0.1	-1.7	-0.7	-0.9	-0.3
Family relationship satisfaction	0.2	0.3	1.3	0.4	0.6	-0.3	-0.4	-0.1	0.3	0.2	0.1	-0.9	-1.1	0.3	-0.0	-0.3	0.5	-0.7	-0.6
Whole body fat-free mass	0.2	1.4	3.7	-1.4	-1.0	-0.3	-0.9	-0.6	-1.9	-1.4	-1.9	-0.7	-0.8	-1.7	-0.3	-1.8	-1.0	-0.7	-0.2
Whole body water mass	0.2	1.4	3.5	-1.3	-1.0	-0.3	-0.9	-0.6	-1.8	-1.4	-1.9	-0.8	-0.9	-1.6	-0.3	-1.7	-1.0	-0.8	-0.3
Pain type(s) experienced in last month: Hip pain	0.2	0.3	1.3	-1.1	-0.4	-0.3	-0.3	0.2	-0.4	-0.4	-0.8	-0.4	-0.0	-0.7	0.1	-0.9	0.0	-0.5	0.5
Medication: Lisinopril	0.2	0.3	1.0	-0.8	-0.4	-1.0	-0.5	0.1	-0.3	-0.2	-1.0	0.3	-0.1	-0.7	0.5	-0.7	0.3	0.4	0.6
Basal metabolic rate	0.2	1.0	2.7	-1.1	-0.8	-0.1	-0.7	-0.4	-1.6	-1.2	-1.6	-0.6	-0.7	-1.4	0.0	-1.5	-0.8	-0.7	0.0
Number of operations (self-reported)	0.2	0.3	1.0	-0.4	-0.5	0.7	-0.2	-0.5	-0.4	-0.5	-0.2	0.0	0.4	-0.3	-1.0	0.2	-0.9	0.1	-0.6
Risk taking	0.2	0.3	0.8	0.7	-0.1	-0.7	0.3	-0.9	-0.2	-0.4	0.2	-0.4	-0.9	0.2	-0.4	0.0	-0.5	-0.8	-0.6
Myopia	0.2	0.4	1.3	-0.1	0.5	0.6	0.5	1.0	0.2	0.5	-0.0	0.4	0.5	0.2	1.1	-0.0	0.8	0.2	1.1
Depressed Affect (Nagel 2018)	0.1	0.2	0.7	0.2	-0.1	-0.2	-0.7	-0.6	-0.5	-0.4	-0.2	-0.7	-0.0	-0.2	0.0	-0.5	-0.4	-0.8	0.0
Alzheimer’s Disease (including proxy)	0.1	0.2	0.9	0.1	-0.1	-0.0	-1.0	-0.1	0.1	0.1	0.0	-0.3	0.1	0.2	0.9	-0.5	0.5	0.0	0.7
Age at First Birth	0.1	0.1	0.6	-0.4	-0.2	-0.1	0.8	0.0	-0.4	-0.3	-0.2	0.2	0.4	-0.4	-0.2	-0.1	-0.3	0.6	0.1
Bipolar Disorder (2011)	0.1	0.1	0.4	-0.1	-0.3	0.2	0.6	0.5	0.1	0.1	-0.1	0.2	-0.1	-0.1	-0.2	0.2	0.0	0.2	-0.2
HDL Cholesterol	0.1	0.2	0.6	0.4	-0.0	-0.6	0.2	-0.5	0.2	-0.1	0.2	-0.5	-0.7	0.1	-0.7	0.2	-0.3	-0.8	-0.7
Schizophrenia (2014)	0.1	0.3	1.0	0.4	-0.3	-0.1	0.1	-0.6	-0.2	-0.2	0.2	-0.5	-0.9	0.2	-0.8	0.2	-0.6	-0.5	-1.0
BMI	0.1	0.7	2.4	0.8	1.0	1.1	0.8	0.8	0.7	0.9	0.5	0.2	-0.2	0.9	1.5	0.0	1.3	0.5	0.8
Height	0.1	1.4	4.5	-1.9	-1.2	-0.3	-0.1	0.0	-1.6	-1.4	-1.9	0.5	0.7	-2.1	-0.9	-0.9	-1.5	0.2	-0.3
Neuroticism	0.1	0.1	0.4	0.6	0.1	-0.3	0.4	0.2	0.2	0.1	0.3	-0.1	-0.3	0.4	-0.5	0.3	-0.3	0.3	-0.7
Pack years adult smoking proportion	0.1	0.2	1.0	0.7	0.2	1.0	-0.3	-0.1	-0.4	-0.2	0.1	-0.1	0.4	0.0	0.4	-0.2	-0.3	-0.5	0.4
Impedance of leg (right)	0.1	0.7	2.1	0.9	0.6	-0.8	0.7	0.4	1.4	0.8	1.3	0.3	0.4	1.1	-0.5	1.3	0.2	0.4	-0.5
Leg fat-free mass (left)	0.1	0.6	1.8	-0.9	-0.6	0.3	-0.7	-0.2	-1.3	-0.9	-1.3	-0.3	-0.7	-1.1	0.2	-1.2	-0.6	-0.4	0.1
Townsend deprivation index at recruitment	0.1	0.1	0.4	0.1	0.3	0.1	-0.2	-0.6	-0.1	-0.1	0.3	-0.4	0.6	0.3	-0.1	-0.0	-0.1	-0.6	0.2
Maternal smoking around birth	0.1	0.2	0.8	-0.1	-0.4	0.2	-0.4	-0.8	-0.4	-0.3	0.1	-0.1	0.6	-0.3	-0.4	-0.0	-0.6	-0.9	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.9	0.3	0.5	0.5	-0.2	0.1	0.1	0.2	-0.1	-0.2	0.1	0.0	1.0	-0.4	0.5	-0.3	0.9
Relative age voice broke	0.1	0.1	0.5	-0.3	-0.2	-0.3	-0.0	-0.3	-0.2	-0.2	-0.0	-0.2	0.0	-0.3	-0.7	0.1	-0.5	-0.7	-0.5
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.7	-0.1	0.1	-0.2	-0.8	-0.2	-0.3	-0.2	-0.3	0.2	-0.2	-0.2	-0.1	0.0	-0.1	-0.2	-0.1
Body mass index (BMI)	0.1	0.4	1.2	0.1	0.1	0.2	-0.3	-0.4	-0.4	-0.1	-0.5	-0.8	-0.7	-0.1	1.0	-1.0	0.4	-1.1	0.5
Leg predicted mass (left)	0.1	0.6	1.8	-0.9	-0.6	0.3	-0.7	-0.2	-1.3	-0.9	-1.3	-0.4	-0.8	-1.1	0.1	-1.2	-0.6	-0.4	0.0
Trunk fat mass	0.1	0.3	1.6	0.5	0.5	0.9	0.7	0.4	0.2	0.4	0.2	0.3	0.3	0.4	1.3	-0.0	0.7	-0.1	0.9
Waist circumference	0.1	0.2	1.1	-0.2	-0.1	0.5	0.3	-0.1	-0.5	-0.2	-0.6	-0.0	0.2	-0.3	1.1	-0.8	0.3	-0.4	0.8
Hearing difficulty/problems with background noise	0.1	0.2	0.6	0.8	0.5	0.3	-0.4	0.1	0.5	0.4	0.6	-0.1	0.6	0.7	0.2	0.2	0.2	-0.0	0.3
Had other major operations	0.1	0.1	0.4	-0.3	-0.4	0.4	-0.4	0.0	-0.1	-0.1	-0.4	0.4	-0.0	-0.3	0.0	-0.0	-0.1	0.6	0.0
Qualifications: None of the above	0.1	0.2	0.9	-0.2	0.1	0.0	0.1	-0.6	-0.1	0.1	-0.2	0.2	0.7	-0.2	0.7	-0.4	0.3	-0.5	0.9
Pain all over the body in last month	0.1	0.1	0.6	0.1	-0.1	0.2	0.5	-0.3	0.0	-0.2	0.3	0.4	0.7	0.0	0.0	0.4	-0.4	-0.5	0.4
Fluid intelligence score	0.1	0.2	1.2	0.0	0.2	-0.5	0.1	1.1	0.2	0.2	-0.2	0.3	-0.7	0.1	0.1	0.2	0.4	0.3	-0.1
Neuroticism score	0.1	0.2	0.4	0.6	0.3	-0.5	0.3	0.6	0.3	0.4	0.2	-0.1	-0.5	0.4	0.2	0.0	0.4	0.5	-0.2
Weight	0.1	0.2	1.2	-0.2	0.1	0.6	0.3	0.3	-0.5	-0.1	-0.6	0.0	-0.2	-0.3	1.1	-0.7	0.3	-0.3	0.8
Arm fat percentage (right)	0.1	0.3	1.6	0.6	0.5	0.8	0.1	-0.0	0.2	0.4	0.3	-0.0	0.2	0.6	1.3	-0.1	0.6	-0.5	0.8
Alcohol intake versus 10 years previously	0.1	0.1	0.5	0.2	0.2	0.2	-0.0	-0.3	-0.2	0.1	0.2	0.2	0.5	0.0	0.4	0.3	-0.2	-0.7	0.6
Falls in the last year	0.1	0.2	0.9	-0.2	-0.7	0.7	0.0	-0.1	-0.1	-0.1	-0.1	0.4	1.0	-0.2	0.4	-0.1	-0.3	-0.0	0.7
Hair/balding pattern: Pattern 3	0.1	0.1	0.4	-0.2	0.1	0.6	-0.1	0.3	0.2	0.2	0.2	-0.4	-0.3	0.3	-0.1	-0.1	0.4	-0.2	0.2
Number of live births	0.1	0.1	0.3	-0.1	0.4	-0.1	0.0	0.1	0.5	0.4	0.3	-0.3	-0.4	0.4	-0.3	0.2	0.3	-0.5	-0.3
Forced expiratory volume in 1-second (FEV1)	0.1	0.5	1.3	1.0	0.4	-0.0	0.7	0.6	0.7	0.5	1.0	0.3	-0.6	1.0	-0.6	1.2	0.0	0.6	-0.9
Qualifications: A levels/AS levels or equivalent	0.1	0.2	1.2	0.6	0.1	0.3	-1.1	-0.3	-0.3	-0.4	0.1	-0.2	0.3	-0.1	-0.2	0.3	-0.8	-0.4	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.7	0.6	0.2	-0.3	0.9	-0.1	-0.0	0.2	-0.0	0.2	-0.3	0.1	0.6	0.2	0.2	0.3	0.1
Medication: Lansoprazole	0.1	0.1	0.7	-0.2	0.0	0.7	0.2	-0.1	-0.1	-0.1	-0.2	0.2	0.9	-0.2	0.4	-0.1	-0.1	0.2	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	0.8	0.4	0.2	0.1	0.2	0.6	0.4	0.4	0.6	0.5	-0.3	0.6	-0.4	0.9	0.1	0.8	-0.4
Arm fat mass (right)	0.1	0.2	0.9	0.0	0.1	0.3	-0.1	-0.3	-0.4	-0.1	-0.4	-0.5	-0.4	-0.1	0.9	-0.8	0.3	-0.8	0.5
Standing height	0.1	0.9	2.9	-1.2	-0.3	0.8	0.9	1.4	-0.6	-0.3	-0.8	1.6	1.1	-1.0	0.2	0.1	-0.2	1.7	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.5	-0.4	-0.4	0.4	-0.6	0.0	-0.2	-0.2	-0.4	-0.5	0.1	-0.3	0.1	-0.4	-0.1	-0.7	0.5
Peak expiratory flow (PEF)	0.1	0.3	0.9	0.6	-0.4	-0.1	-0.8	-0.1	-0.2	-0.2	0.4	-0.5	-0.8	0.5	-0.8	0.4	-0.7	-0.6	-0.9
Forced vital capacity (FVC), Best measure	0.1	0.3	2.2	-0.6	-0.4	0.3	0.1	0.8	0.0	0.1	-0.1	0.8	0.4	-0.1	-0.1	0.2	0.2	1.5	0.2
Body fat percentage	0.1	0.5	1.8	0.9	0.8	0.8	0.7	0.2	0.6	0.7	0.7	0.1	0.3	0.9	1.4	0.2	0.9	-0.4	0.9
Leg fat percentage (right)	0.1	0.4	1.4	1.1	0.6	-0.1	0.5	-0.4	0.4	0.3	0.6	-0.7	-0.5	0.9	0.6	-0.0	0.3	-1.2	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	1.0	0.4	-0.1	-0.7	-0.4	-0.3	-0.2	-0.2	-0.0	-0.5	-0.1	0.1	-0.2	-0.1	-0.3	-1.0	-0.1
Shortness of breath walking on level ground	0.1	0.1	0.5	-0.1	-0.0	0.4	0.2	-0.3	-0.2	-0.2	-0.1	-0.5	0.0	-0.1	-0.1	-0.4	-0.3	-0.7	-0.0
Medication for pain relief, constipation, heartburn	0.1	0.2	0.6	-0.7	-0.7	0.2	0.0	0.4	-0.0	-0.1	-0.4	0.5	0.1	-0.4	0.6	-0.2	0.3	0.5	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.7	0.0	0.0	-0.2	-0.8	0.7	0.0	0.2	-0.0	-0.2	-0.8	0.1	0.3	-0.1	0.5	0.2	-0.0
Alcohol intake frequency.	0.1	0.1	0.5	-0.1	-0.1	-0.4	-0.4	-0.1	-0.7	-0.2	-0.5	0.6	-0.6	-0.6	-0.0	0.1	-0.3	-0.1	-0.0
Comparative height size at age 10	0.1	0.7	2.7	0.1	0.1	1.6	1.4	0.8	-0.1	0.0	0.2	1.3	1.1	-0.1	0.2	0.6	-0.2	1.2	0.6
Age at last live birth	0.1	0.2	0.6	-0.1	0.4	0.5	0.5	0.8	0.8	0.5	0.3	-0.2	-0.2	0.4	0.2	0.2	0.6	-0.3	0.4
Leg fat-free mass (right)	0.1	0.5	1.8	-0.8	-0.4	0.4	-0.5	-0.0	-1.2	-0.7	-1.3	-0.2	-0.6	-1.0	0.4	-1.1	-0.3	-0.3	0.4
Arm fat percentage (left)	0.1	0.5	2.4	0.7	0.6	1.0	0.3	0.2	0.3	0.5	0.4	0.0	0.2	0.7	1.6	-0.1	0.9	-0.4	1.1
Average weekly red wine intake	0.1	0.2	0.6	-0.0	0.2	0.8	0.2	0.5	-0.0	-0.0	0.3	0.5	0.1	0.2	-0.8	0.8	-0.3	0.4	-0.4
Loneliness, isolation	0.1	0.1	0.2	0.0	-0.1	-0.2	-0.5	-0.2	-0.3	-0.3	-0.2	-0.4	-0.4	-0.1	0.1	-0.4	-0.1	0.0	0.1
Friendships satisfaction	0.1	0.2	1.0	0.6	0.4	0.4	-0.3	-0.4	-0.2	-0.1	0.1	-0.7	-0.6	0.2	-0.0	-0.1	-0.0	-1.0	-0.2
Qualifications: nursing, teaching	0.1	0.2	1.0	-0.2	-0.6	-0.8	-0.2	0.3	-0.2	-0.4	-0.4	-0.4	-1.0	-0.2	-0.0	-0.3	-0.1	0.1	-0.3
Leg predicted mass (right)	0.1	0.5	1.7	-0.8	-0.4	0.4	-0.5	0.0	-1.2	-0.7	-1.3	-0.2	-0.5	-1.0	0.5	-1.1	-0.3	-0.3	0.4
Financial situation satisfaction	0.1	0.1	0.6	0.2	0.0	0.2	-0.7	-0.2	-0.2	0.1	0.1	-0.2	-0.2	0.2	-0.2	0.2	0.1	-0.5	0.0
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.2	-0.4	-0.1	-0.1	-0.5	-0.4	0.0	0.0	-0.0	-0.1	0.5	0.1	-0.2	-0.1	0.1	0.4	0.2
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.3	-0.4	-0.3	0.3	-0.3	-0.4	-0.5	-0.3	-0.1	-0.3	0.4	-0.2	-0.5	-0.3	-0.3	-0.4	-0.1
Leg fat percentage (left)	0.1	0.5	1.3	1.1	0.8	-0.1	0.8	-0.2	0.6	0.6	0.7	-0.5	-0.4	1.0	0.9	0.0	0.7	-1.1	0.3
Unable to work because of sickness or disability	0.1	0.1	0.3	0.1	0.2	0.4	-0.5	-0.2	0.3	0.2	0.5	-0.4	0.4	0.4	0.1	0.0	0.2	-0.1	0.1
Commuting to job workplace: Cycle	0.1	0.2	0.8	-0.7	-0.1	0.2	-0.1	0.9	0.0	0.0	-0.3	0.6	0.4	-0.3	0.3	-0.1	0.5	0.3	0.6
Pack years of smoking	0.1	0.2	1.0	0.5	0.1	1.0	-0.2	-0.2	-0.5	-0.3	-0.0	-0.1	0.5	-0.1	0.3	-0.3	-0.4	-0.7	0.4
Leg fat mass (left)	0.1	0.2	0.9	0.6	0.5	0.1	0.4	-0.1	0.1	0.2	0.0	-0.5	-0.5	0.4	0.9	-0.4	0.5	-0.8	0.3
Breast Cancer	0.0	0.1	0.3	0.3	-0.0	-0.1	0.2	0.4	-0.2	0.2	-0.1	0.6	-0.2	0.1	0.1	0.4	-0.0	0.4	-0.1
Blood Platelet Count	0.0	0.4	1.7	0.3	0.6	0.1	0.2	0.8	0.8	0.4	0.6	-0.4	-0.6	0.8	-1.1	0.0	0.8	0.2	-1.3
Tanning	0.0	0.5	2.2	0.0	0.4	0.6	0.1	1.5	0.6	0.6	-0.1	0.1	0.9	0.2	0.9	-0.6	1.3	0.9	0.4
Forced vital capacity (FVC)	0.0	0.2	1.0	0.1	-0.2	0.1	0.3	0.6	0.2	0.1	0.3	0.4	0.2	0.3	-0.5	0.5	-0.1	1.0	-0.4
Medication: Ventolin 100micrograms inhaler	0.0	0.1	0.2	0.3	-0.1	-0.3	0.5	0.1	0.1	0.1	0.1	0.4	0.1	0.1	0.1	0.2	-0.1	0.5	-0.1
Chronic bronchitis/emphysema (mother)	0.0	0.1	0.2	-0.1	0.2	0.3	0.0	-0.2	-0.4	-0.1	-0.3	0.1	0.2	-0.4	0.2	-0.3	0.1	0.2	0.1
Whole body fat mass	0.0	0.2	0.8	0.1	0.1	0.4	0.2	-0.2	-0.2	-0.0	-0.2	-0.4	-0.2	0.1	0.9	-0.6	0.3	-0.8	0.5
Leg fat mass (right)	0.0	0.2	0.9	0.4	0.4	0.1	0.2	-0.2	-0.0	0.0	-0.1	-0.6	-0.5	0.3	0.7	-0.5	0.2	-1.0	0.2
Arm fat mass (left)	0.0	0.2	1.1	0.1	0.2	0.5	0.0	-0.1	-0.3	0.0	-0.3	-0.4	-0.3	0.0	1.0	-0.7	0.4	-0.6	0.6

Hub : Genes

ACTR2

Models

Trait associations