TWAS
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Traits
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Lung FEV1/FVC ratio
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chr6:89,941,356-91,704,536
Best TWAS P=2.36e-10 · Best GWAS P=5.37e-16 conditioned to 4.52e-07
90M
90.2M
90.4M
90.6M
90.8M
91M
91.2M
91.4M
91.6M
91.8M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
YFS
Blood
BACH2
0.03
0.01
lasso
4
0.01
0.00069
7.9
-6.3
2.4e-10
-0.78
0.01
0.98
TRUE