TWAS
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Traits
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Traits
:
Lung FEV1/FVC ratio
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chr6:73,090,786-74,157,617
Best TWAS P=2.62e-07 · Best GWAS P=1.27e-44 conditioned to 2.03e-39
73.2M
73.4M
73.6M
73.8M
74M
74.2M
0
10
20
30
40
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Prostate Adenocarcinoma
KCNQ5
0.1
0
blup
291
0.02
0.0027
3.2
-5.2
2.6e-07
-0.25
0.07
0.34
TRUE