[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr6:108,183,628-110,710,018

Best TWAS P=2.1e-16 · Best GWAS P=2.77e-82 conditioned to 6.91e-56

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Artery Coronary	RP11-425D10.10	0.31	0.00	enet	20	0.01	1.3e-01	7.3	-8.2	2.1e-16	0.15	0.04	0.05	TRUE
12	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ARMC2	0.04	0.05	lasso	1	0.04	3.4e-04	7.3	-7.3	3.4e-13	0.04	0.22	0.02	TRUE
10	YFS	Blood	FOXO3	0.03	0.01	lasso	3	0.02	3.2e-07	-7.6	7.2	4.6e-13	-0.08	1.00	0.00	TRUE
7	METSIM	Adipose	SMPD2	0.06	0.08	enet	14	0.08	2.0e-12	-3.1	-6.6	3.2e-11	0.31	1.00	0.00	TRUE
3	GTEx	Brain Cerebellar Hemisphere	ARMC2	0.57	0.30	enet	22	0.32	7.0e-09	1.5	6.4	1.3e-10	-0.37	0.84	0.11	TRUE
5	GTEx	Pancreas	FOXO3	0.12	0.00	enet	17	0.05	3.0e-03	-0.4	-5.7	1.6e-08	0.01	0.07	0.04	TRUE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	SESN1	0.02	0.04	lasso	4	0.04	1.1e-04	6.3	6.3	2.4e-10	-0.01	0.52	0.01	FALSE
8	NTR	Blood	SESN1	0.03	0.04	lasso	3	0.03	5.4e-11	6.3	6.3	2.6e-10	-0.01	1.00	0.00	FALSE
11	YFS	Blood	SESN1	0.10	0.12	lasso	15	0.12	1.4e-36	6.4	6.3	3.8e-10	-0.02	1.00	0.00	FALSE
9	YFS	Blood	CD164	0.03	0.01	blup	382	0.02	1.9e-07	2.0	-5.4	7.2e-08	0.03	1.00	0.00	FALSE
1	GTEx	Artery Aorta	AK9	0.16	0.14	enet	32	0.14	3.7e-08	4.7	5.3	1.5e-07	-0.12	1.00	0.00	FALSE
4	GTEx	Lung	ARMC2	0.12	0.01	lasso	5	0.03	1.6e-03	1.6	5.2	1.6e-07	-0.35	0.06	0.16	FALSE
6	GTEx	Spleen	RP11-425D10.10	0.17	0.04	enet	26	0.12	4.7e-04	-3.0	-5.2	2.5e-07	0.13	0.27	0.06	FALSE