TWAS
hub
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Usage
Models
Genes
Traits
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Traits
:
Lung FEV1/FVC ratio
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chr6:121,058,929-122,457,698
Best TWAS P=3.26e-10 · Best GWAS P=2.2e-15 conditioned to 6.38e-08
121M
121.2M
121.4M
121.6M
121.8M
122M
122.2M
122.4M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
METSIM
Adipose
GJA1
0.06
0.01
bslmm
348
0.03
4.0e-05
5.5
6.3
3.3e-10
0.53
0.01
0.97
TRUE
1
GTEx
Cells Transformed fibroblasts
GJA1
0.13
0.07
enet
14
0.13
2.9e-10
4.5
6.0
2.5e-09
0.13
0.96
0.00
FALSE